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Phase separations in graded-indium content InGaN/GaN multiple quantum wells and its function to high quantum efficiency

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Journal of Semiconductors 2012年第5期33卷 13-16页

作者：郭洪英孙元平 Yong-Hoon Cho eun-kyung Suh Hai-Joon Lee Rak-Jun choi Yoon-Bong Hahn Institute of Science and Technology for Opto-Electronic Information Yantai University Department of Physics Korea Advanced Institute of Science and Technology School of Semiconductor and Chemical Engineering Semiconductor Physics Research CenterChonbuk National University School of Chemical Engineering Chonbuk National University

Phase separations have been studied for graded-indium content In_xGa_（1-x）N/GaN multiple quantum wells（MQWs） with different indium contents by means of photoluminescence（PL）,cathodeluminescence（CL） and time-resolved PL（TRPL） *** the main emission peaks,all samples show another 2 peaks at the high and low energy parts of the main peaks in PL when excited at 10 *** images show a clear contrast for 3 samples,which indicates an increasing phase separation with increasing indium *** spectra at 15 K of the main emissions show an increasing delay of rising time with indium content,which means a carrier transferring from low indium content structures to high indium content structures.

关键词： carrier transfer phase separation graded-indium content multiple quantum wells

Effect of trapping vascular endothelial growth factor-A in a murine model of dry eye with inflammatory neovascularization

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International Journal of Ophthalmology(English edition) 2016年第11期9卷 1541-1548页

作者： Jin Woo Kwon Jin A choi eun Young Shin Tae Yoon La Dong Hyun Jee Yeon Woong Chung Yang kyung Cho Department of Ophthalmology St.Vincent's HospitalCollege of Medicinethe Catholic University of Korea Research Institute of Medical Science St.Vincent's Hospitalthe Catholic University of Korea

AIM： To evaluate whether trapping vascular endothelial growth factor-A（VEGF-A） would suppress angiogenesis and inflammation in dry eye corneas in a murine corneal suture ***： We established two groups of animals, one with non-dry eyes and the other with induced dry *** both groups, a corneal suture model was used to induce inflammation and neovascularization. Each of two groups was again divided into three subgroups according to the treatment; subgroup I（aflibercept）,subgroup II（dexamethasone） and subgroup III（phosphate buffered saline, PBS）. Corneas were harvested and immunohistochemical staining was performed to compare the extents of neovascularization and CD11b＋ cell infiltration. Real-time polymerase chain reaction was performed to quantify the expression of inflammatory cytokines and VEGF-A in the ***： Trapping VEGF-A with aflibercept resulted in significantly decreased angiogenesis and inflammation compared with the dexamethasone and PBS treatments in the dry eye corneas（all P 〈0.05）, but with no such effects in non-dry eyes. The anti-inflammatory and antiangiogenic effects of VEGF-A trapping were stronger than those of dexamethasone in both dry eye and non-dry eye corneas（all P 〈0.05）. The levels of RNA expression of VEGF-A, TNF-alpha, and IL-6 in the aflibercept subgroup were significantly decreasedcompared with those in the PBS subgroup in the dry eye ***： Compared with non-dry eye corneas,dry eye corneas have greater amounts of inflammation and neovascularization and also have a more robust response to anti-inflammatory and anti-angiogenic agents after ocular surface surgery. Trapping VEGF-A is effective in decreasing both angiogenesis and inflammation in dry eye corneas after ocular surface surgery.

关键词： dry eye aflibercept neovascularization inflammation dexamethasone

Risk factor analysis for meta plastic gastritis in Koreans

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World Journal of Gastroenterology 2006年第16期12卷 2584-2587页

作者： Soonami choi Yun Jeong Lim Sue kyung Park Center for Health Promotion Samsung Medical CenterSeoulKorea Department of Internal Medicine Dongguk University International HospitalDongguk University College of MedicineGoyangKorea Department of Preventive Medicine Seoul National University College of MedicineSeoulKorea

AIM： To conduct a retrospective study to determine the risk factors for development of metaplastic gastritis in Korean population. METHODS： The database of 113449 subjects who underwent a gastroscopy for the purpose of a regular check-up at center for health promotion, Samsung medical center during 5 years was collected and retrospectively analyzed. Among them, 5847 subjects who had endoscopically diagnosed as a metaplastic gastritis or 10076 normal as well as answered to questionnaire were included for present study. The subjects were divided into 2 groups; Group Ⅰ, normal and Group Ⅱ, metaplastic gastritis. Age, gender, Helicobacter pylori （H pylori） seropositivity, body mass index （BMI）, family history of cancer, smoking, alcohol consumption, total daily calories, folate and salt intake and dietary habit （out-eating, overeating, irregular eating） were retrieved from questionnaire or electronic medical record and compared between group Ⅰ and group Ⅱ. RESULTS： The prevalence of group Ⅱwas 11% （13578/113449） increasing its prevalence with age （P=0.000）. But, there was no significant association between 2 groups in BMI, family history of cancer, alcohol consumption, total daily calories, folate and salt intake and dietary habit （out-eating, overeating, irregular eating）. Old age （P=0.000）, male gender （P=0.000）, H pylori seropositivity （P= 0.010） and current smoker （P=0.000） were significantly more common in group II at multiple logistic regression model. CONCLUSION： Our data suggested that old age, male gender, H pylori seropositivity and smoking were risk factors for metaplastic gastritis, precancerous lesion of gastric cancer.

关键词： Intestinal metaplasia Risk factors

Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials

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Acta Pharmaceutica Sinica B 2016年第4期6卷 297-307页

作者： eun Ji Hong Dae Gun choi Min Suk Shim Division of Bioengineering Incheon National University

Photodynamic therapy(PDT) is an emerging, non-invasive therapeutic strategy that involves photosensitizer(PS) drugs and external light for the treatment of diseases. Despite the great progress in PS-mediated PDT, their clinical applications are still hampered by poor water solubility and tissue/cell specificity of conventional PS drugs. Therefore, great efforts have been made towards the development of nanomaterials that can tackle fundamental challenges in conventional PS drug–mediated PDT for cancer treatment. This review highlights recent advances in the development of nano-platforms, in which various functionalized organic and inorganic nanomaterials are integrated with PS drugs, for significantly enhanced efficacy and tumor-selectivity of PDT.

关键词： Organic nanomaterials Inorganic nanomaterials Nanoparticles Photodynamic therapy Photosensitizer Targeted therapy Cancer therapy Near-infrared light

Comparison of Adsorption Isotherms of Methylxanthines on C_(18) Column

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Chemical Research in Chinese Universities 2010年第5期26卷 729-734页

作者： BI Wen-tao choi Dae Ki ROW kyung Ho Department of Chemical Engineering Inha University lncheon 402-751 Korea Center for Fuel Cell Research Korea Institute of Science and Technology Seoul 136-791 Korea

A comparison of the adsorption isotherms of caffeine, theophylline and theobromine and the competitive adsorption of the three compounds on a C18 column were investigated. The experimental parameters of the equilibrium isotherms were estimated by linear and nonlinear regression analyses. The linear equation as a function of the adsorption concentration of the single compound in its solution and the competitive adsorption of a single compound in a mixed solution were then determined. The adsorption equilibrium data were then correlated to the linear, Langmuir, Freundlich, Langmuir-Freundlich and stoichiometric displacement theory for adsorption（SDT-A） isotherm models. The mixed compounds of the three compounds were competitively adsorbed on the C18 particles. The expression of stoichiometric displacement theory for adsorption was found to be more suitable for adsorption of methylxanthines on a C18 column.

关键词： Adsorption isotherm Methylxanthine High-performance liquid chromatography

The Early Emotional Responses and Central Issues of People in the Epicenter of the COVID-19 Pandemic: An Analysis from Twitter Text Mining

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International Journal of Mental Health Promotion 2023年第1期25卷 21-29页

作者： eun-Joo choi Yun-Jung choi Department of Nursing Kyungin Women’s UniversityIncheon21041South Korea Red Cross College of Nursing Chung-Ang UniversitySeoul06974South Korea

This study aimed to explore citizens’emotional responses and issues of interest in the context of the coronavirus disease 2019(COVID-19)*** dataset comprised 65,313 tweets with the location marked as New York *** data collection period was four days of tweets when New York City imposed a lockdown order due to an increase in conﬁrmed *** analysis was performed using R *** emotional responses in tweets were analyzed using the Bing and NRC(National Research Council Canada)*** tweets’central issue was identiﬁed by Text Network *** tweets were classiﬁed as either positive or negative,the negative sentiment was *** the NRC dictionary,eight emotional classiﬁcations were devised:“trust,”“fear,”“anticipation,”“sadness,”“anger,”“joy,”“surprise,”and“disgust.”These results indicated that citizens showed negative and trusting emotional reactions in the early days of the ***,citizens showed a strong interest in overcoming and coping with other people such as social *** were concerned about the conﬁrmation of COVID-19 infection status and *** should be made to ensure citizens’psychological stability by promptly informing them of the status of infectious disease management and the route of infection.

关键词： COVID-19 community mental health emotional responses text mining Twitter

Foldable and washable textile-based OLEDs with a multi-functional near-room-temperature encapsulation layer for smart e-textiles

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npj Flexible Electronics 2021年第1期5卷 123-131页

作者： So Yeong Jeong Hye Rin Shim Yunha Na Ki Suk Kang Yongmin Jeon Seungyeop choi eun Gyo Jeong Yong Cheon Park Ha-eun Cho Junwoo Lee Jeong Hyun Kwon Sung Gap Im kyung Cheol choi School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea Department of Clothing and Textiles Chonnam National UniversityGwangjuRepublic of Korea Department of Display and Semiconductor Engineering Sun Moon UniversityAsanRepublic of Korea Department of Chemical and Biomolecular Engineering and KI for the NanoCentury Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea.

Wearable electronic devices are being developed because of their wide potential applications and user *** them,wearable organic light emitting diodes(OLEDs)play an important role in visualizing the data signal processed in wearable electronics to *** this study,textile-based OLEDs were fabricated and their practical utility was *** textilebased OLEDs exhibited a stable operating lifetime under ambient conditions,enough mechanical durability to endure the deformation by the movement of humans,and washability for maintaining its optoelectronic properties even in water condition such as rain,sweat,or *** this study,the main technology used to realize this textile-based OLED was multi-functional nearroom-temperature *** outstanding impermeability of TiO_(2)film deposited at near-room-temperature was *** internal residual stress in the encapsulation layer was controlled,and the device was capped by highly crosslinked hydrophobic polymer film,providing a highly impermeable,mechanically flexible,and waterproof encapsulation.

关键词： OLEDs layer film

Effects of microalgal polyunsaturated fatty acid oil on body weight and lipid accumulation in the liver of C57BL/6 mice fed a high fat diet

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The Journal of Biomedical Research 2016年第3期30卷 234-242页

作者： Ryeo-eun Go kyung-A Hwang Geon-Tae Park Hae-Miru Lee Geum-A Lee Cho-Won Kim So-Ye Jeon Jeong-Woo Seo Won-kyung Hong kyung-Chul choi Laboratory of Biochemistry and Immunology College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk ASI/KR/KS001 Republic of Korea Korea Research Institute of Bioscience & Biotechnology Jeongup Jeonbuk ASI/KR/KS004 Republic of Korea LED Agri-bio Fusion Technology Research Center College of Environmental & Bioresource Science Chonbuk National University Iksan Campus Jeonbuk ASI/KR/KS004 Republic of Korea

Dietary polyunsaturated fatty acids （PUFAs）, which are abundant in marine fish oils, have recently received global attention for their prominent anti-obesogenic effects. Among PUFAs, eicosapentaenoic acid （EPA; 20：5n-3） and docosahexaenoic acid （DHA; 22：6n-3）, which are n-3 long-chain PUFAs widely referred to as omega-3 oils, were reported to prevent the development of obesity in rodents and humans. In the present study, we evaluated the anti-obesity effects of microalgal oil on high-fat induced obese C57BL/6 mice, compared with commercial omega-3 fish oil and vegetable corn oil. Microalgal oil is an inherent mixture of several PUFAs, including EPA, DHA and other fatty acids produced from a marine microalgal strain of Thraustochytriidae sp. derived mutant. It was found to contain more PUFAs （〉80%） and more omega-3 oils than commercial omega-3 fish oil （PUFAs 〉31%） and corn oil （PUFAs 59%）. All three types of oils induced weight loss in high-fat-induced obese mice, with the loss induced by microalgal oil being most significant at 9 weeks （10% reduction）. However, the oils tested did not improve blood lipid levels, although microalgal oil showed an apparent inhibitory effect on lipid accumulation in the liver. These findings may be attributed to the higher PUFA content, including omega-3 oils of microalgal oil than other oils. Collectively, these findings suggest that microalgal oil, derived from Thraustochytriidae sp. derived mutant, is a prominent candidate for replacement of omega-3 fish oils based on its apparent anti-obesity effect in vivo.

关键词： anti-obesity polyunsaturated fatty acid saturated fatty acid omega-3 oil microalgae

Massive retroperitoneal hematoma as an acute complication of retrograde intrarenal surgery:A case report

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World Journal of Clinical Cases 2021年第16期9卷 3914-3918页

作者： Taesoo choi Jeonghyouk choi Gyeong eun Min Dong-Gi Lee Department of Urology School of MedicineKyung Hee UniversitySeoul 05278South Korea

BACKGROUND Retrograde intrarenal surgery(RIRS)has been proven to be a safe and effective treatment modality in large-scale quantitative ***,although its safety profile has been established,it also has a potential risk of life-threatening *** here describe our experience with a patient who developed a huge periureteral hematoma after RIRS with holmium laser *** SUMMARY A 73-year-old woman visited our center with a complaint of gross *** enhanced computed tomography(CT)scan revealed a 1.5-cm left renal pelvis stone with *** patient underwent *** the surgery,a 12/14-Fr ureteral access sheath was applied and a 6-Fr ureteral catheter was indwelled *** postoperative day 1,she experienced aggravated left flank pain and left lower-quadrant tenderness without rebound tenderness.A follow-up CT scan was taken,which revealed a huge hematoma in the periureteral space,not in the perirenal space,with suspicious contrast medium *** angiography was performed;however,it showed no evidence of active *** was conservatively managed with hydration and antibiotic and nonsteroidal anti-inflammatory drug therapy,and was discharged on postoperative day ***,she visited our outpatient department with recurrent left flank pain at 5 d from *** confirmed that the double J-stent was *** rule out stent malfunction,the stent was *** size of the hematoma was observed in the imaging studies,and conservative management for candiduria was performed for 1 *** Although RIRS is an effective and safe procedure for the management of renal stones,clinicians should be aware of its potential complications.

关键词： Retroperitoneal hematoma Ureteral access sheath Retrograde intrarenal surgery Acute complication Case report