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The Application of the Korean Dietary Pattern Score;KNHANES (Korean National Health and Nutrition Examination Survey) 2007

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Food and Nutrition Sciences 2012年第12期3卷 1688-1696页

作者： kyung Won Lee Ji Eun Oh Mi sook Cho Department of Nutrition Science and Food Management Ewha Womans University Seoul Korea.

The aim of this study was to apply the Korean Dietary Pattern Score (KDPS) to Korean subjects based on traditional Korean-style meals. The KDPS is based on the 3-Chup Bansang (the traditional Korean daily table setting) and considers the intake of 6 major food groups according to the Korean Dietary Reference Intakes (KDRIs). The KDPS consists of 2 parts: the Korean-Style Meal Score (KSMS) and the Food Group Score (FGS). The KDPS was applied dietary data collected during the Korean National Health and Nutrition Examination Survey (KNHANES) in 2007. Socio-demographic status, gender, age, and body mass index are all factors that have been shown to be meaningful predictors for the KDPS. When the effect of the KDPS on risk of disease was evaluated, a higher total KDPS was associated with a decreased risk of elevated systolic blood pressure (p < 0.05) and hypercholesterolemia (p < 0.05). In addition, as the KSMS increased, the risk of central obesity (p < 0.05) and hypertension (p < 0.01) significantly decreased. A higher total KDPS suggests a greater diversity of food intake, and therefore greater dietary diversity appears to lower the risk of disease. The KDPS is relevant because it integrates scores for Korean-style meal patterns and meal evaluation from a nutritional perspective. In conclusion, the KDPS is appropriate for evaluating the quality of diet, adherence to Korean-style meal patterns, and risk of related diseases. These results will be useful for evaluating the nation’s dietary patterns, nutrition, and health status when planning nutrition policies and programs.

关键词： Korean Dietary Pattern Korean Dietary Index Korean Dietary Pattern Score (KDPS) Korean-Style MealScore (KSMS) Food Group Score (FGS)

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Bawu Decoction(八物汤) Ameliorates Benign Prostatic Hyperplasia in Rats

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Chinese Journal of Integrative Medicine 2017年第8期23卷 611-616页

作者： Ji-Hwan Eom Se-Yun Cheon kyung-sook Chung Myung-Dong Kim Hyo-Jin An Department of Physiology College of Korean Medicine Sangji University Wonju-si Gangwon-do 220-702 Republic of Korea Department of Pharmacology College of Korean Medicine Sangji University Wonju-si Gangwon-do 220-702 Reoublic of Korea

Objective：To evaluate the efficacy of Bawu Decoction（八物汤,BWD,Palmul-tang in Korean）against benign prostatic hyperplasia（BPH）.Methods：Twenty-four male Wistar rats were divided into 4 groups,with 6 rats in each *** 4 study groups included sham-operated group（CON）,BPH model group,finasteride-treated group,and BWD-treated *** the groups except CON group received a subcutaneous injection of 10 mg/kg of testosterone,while CON group received *** at a dose of 5 mg/kg was administered to the finasteride-treated group for a period of 4 *** group received BWD at a dose of 200 mg/kg for 4 *** prostatic weight,prostate weight to body weight ratio,relative prostate weight ratio,serum testosterone and dihydrotestosterone（DHT）level,and histological analysis of prostatic tissue were ***：Compared to BPH model group,BWD administration was associated with reductions in prostatic weight,prostate and relative prostate weight ratio weight to body weight ratio（P〈0.05）.The concentration of serum testosterone and DHT were higher in BPH group compared with CON group（P〈0.05）.Administration of finasteride and BWD suppressed the elevation of serum testosterone and DHT levels significantly（both P〈0.05）.In addition,BWD suppressed the growth of prostatic tissue（P〈0.05）.Conclusion：BWD has suppressant effects on development of BPH through inhibition of serum testosterone and DHT.

关键词： benign prostatic hyperplasia Bawu Decotion Palmul-tang finasteride testosterone,dihydrotesterone rat

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Optimal culture conditions for the generation of natural killer cell-induced dendritic cells for cancer immunotherapy

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Cellular & Molecular Immunology 2012年第1期9卷 45-53页

作者： Thanh-Nhan Nguyen-Pham Deok-Hwan yang Truc-Anh Thi Nguyen Mi-Seon Lim Cheol Yi Hong Mi-Hyun Kim Hyun Ju Lee Youn-kyung Lee Duck Cho Soo-Young Bae Jae-sook Ahn Yeo-Kyeoung Kim Ik-Joo Chung Hyeoung-Joon Kim Je-Jung Lee Research Center for Cancer Immunotherapy Chonnam National University Hwasun HospitalJeollanamdoKorea Department of Hematology-Oncology Chonnam National University Hwasun HospitalJeollanamdoKorea Vaxcell-Bio Therapeutics JeollanamdoKorea The Brain Korea 21 Project Center for Biomedical Human Resources at Chonnam National UniversityGwangjuKorea

Dendritic cell(DC)-based vaccines continue to be considered an attractive tool for cancer *** require an additional signal from the environment or other immune cells to polarize the development of immune responses toward T helper 1(Th1)or Th2 *** play a role in natural killer(NK)cell activation,and NK cells are also able to activate and induce the maturation of *** investigated the types of NK cells that can induce the maturation and enhanced function of DCs and the conditions under which these interactions *** that were activated by resting NK cells in the presence of inflammatory cytokines exhibited increased expression of several costimulatory molecules and an enhanced ability to produce *** cell-stimulated DCs potently induced Th1 polarization and exhibited the ability to generate tumor antigen-specific cytotoxic T lymphocyte *** data demonstrate that functional DCs can be generated by coculturing immature DCs with freshly isolated resting NK cells in the presence of Toll-like receptor agonists and proinflammatory cytokines and that the resulting DCs effectively present antigens to induce tumor-specific T-cell responses,which suggests that these cells may be useful for cancer immunotherapy.

关键词： cancer immunotherapy dendritic cells natural killer cells signal

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Type I and II interferons enhance dendritic cell maturation and migration capacity by regulating CD38 and CD74 that have synergistic effects with TLR agonists

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Cellular & Molecular Immunology 2011年第4期8卷 341-347页

作者： Thanh-Nhan Nguyen-Pham Mi-Seon Lim Truc Anh Thi Nguyen Youn-kyung Lee Chun-Ji Jin Hyun Ju Lee Cheol Yi Hong Jae-sook Ahn Deok-Hwan yang Yeo-Kyeoung Kim Ik-Joo Chung Byoung Chul Park Hyeoung-Joon Kim Je-Jung Lee Research Center for Cancer Immunotherapy Chonnam National University Hwasun HospitalJeollanamdoKorea Department of Hematology-Oncology Chonnam National UniversityGwangjuKorea The Brain Korea 21 Project Center for Biomedical Human Resources at Chonnam National UniversityGwangjuKorea Vaxcell-Bio Therapeutics JeollanamdoKorea Korea Research Institute of Bioscience and Biotechnology(KRIBB) DaejeonKorea

The major limitation for the maturation of dendritic cells(DCs)using Toll-like receptor(TLR)agonists is their decreased ability to migrate into lymph nodes compared with conventional ***38 can be used as a multifunctional marker to modulate migration,survival and Th1 responses of ***74 has been shown to negatively regulate DC *** goal of this study was to investigate the combinations of TLR agonists and interferons(IFNs)that most effectively regulate CD38 and CD74 expression on *** TLR agonist stimulation in combination with IFN-a and IFN-c was the best method for regulating CD38 and CD74 expression and inducing the highest secretion of *** in vitro migration assay showed that DCs treated with this combination had significantly enhanced migratory ability,similar to that observed in cells expressing CD38,CD74 and *** results of this study suggest that an alternative maturation protocol in which two TLR ligands are combined with type I and II IFNs generates potent DCs that have both a high migratory capacity and high IL-12p70 production.

关键词： CD38 CD74 dendritic cells interferon Toll-like receptor

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Relationship between insulin resistance, obesity and serum prostate-specific antigen levels in healthy men

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Asian Journal of Andrology 2010年第3期12卷 400-404,I0011页

作者： June Hyun Han Yong Taec Lee kyung Won Kwak Seung Hyun Ahn In Ho Chang Soon Chul Myung Seung Young Oh Yong-Seong Lee Wonyong Kim Young-Woo Jin Tae-In Choi sook Hee Sung Department of Urology KEPCO Medical Foundation Hanil General Hospital Seou1132-703 Korea Department of Urology Chung-Ang University Hospital Seoul 140-757 Korea Department of Urology Hyundae General Hospital Namyangju 472-865 Korea Department of Urology Hallym University Hangang Sacred Heart Hospital Seoul 150-719 Korea Department of Microbiology College of Medicine Chung-Ang University Seoul 156- 756 Korea Radiation Health Research Institute Korea Hydro ＆ Nuclear Power Co. LTD Seoul 132-703 Korea

The purpose of this study was to determine the relationship between insulin resistance, obesity and serum prostate-specific antigen （PSA） levels in healthy men with serum PSA level below 4 ng mL-1. The men included in the study cohort were 11 827 healthy male employees of the Korea Hydro and Nuclear Power Co., LTD who had undergone medical checkups including fasting glucose, fasting insulin and serum PSA between January 2003 and December 2008. Insulin resistance was calculated by homeostasis model assessment （HOMA [fasting glucose × fasting insulin]/22.5） and quantitative insulin sensitivity check index （QUICK/; 1/[log （fasting insulin）＋ log （fasting glucose）]）. Age-adjusted body mass index （BMI） was significantly increased according to increasing quartile of insulin resistance as determined by HOMA and QUICKI, respectively, in analysis of variance （ANOVA） test and Duncan＇s multiple comparison test （P 〈 0.001）, but age-adjusted serum PSA concentration was significantly decreased according to increasing quartile of insulin resistance as determined by HOMA and QUICK/（P 〈 0.001）. Age, BMI, insulin resistance by HOMA or QUICK/were significantly independent variables to serum PSA level in a multivariate linear regression analysis （P 〈 0.001）. Insulin resistance was a significant independent variable to serum PSA level along with BMI. Insulin resistance and BMI were negatively correlated with serum PSA level in healthy men. Insulin resistance was positively correlated with BMI.

关键词： body mass index insulin resistance metabolic syndrome X obesity prostate-specific antigen

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Effects of a Health Promotion Program on Elementary Students’ Physical and Mental Health

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Open Journal of Nursing 2015年第9期5卷 805-812页

作者： Insook Lee kyung-sook Bang Sungjae Kim Heeseung Choi Inju Hwang College of Nursing The Research Institute of Nursing Science Seoul National University Seoul Korea College of Nursing Seoul National University Seoul Korea

Many health promotion programs have been implemented to prevent obesity and mental health problems among school-aged children. However, only a few programs included both physical and psychological measures to assess the effects of the program. The present study was designed to test the effects of a 6-week health promotion program on physical and mental health among school-aged children using physiological and psychological measures. A total of 74 elementary school students (4th and 5th grade) recruited from urban (n = 51) and rural areas (n = 23) participated in the study. We used the Korean version of the Kovacs’ Children’s Depression Inventory and the Conners-Wells’ Adolescent Self-Report Scale-Short Form (CASS-S) to measure levels of depression and hyperactivity, respectively. To assess children’s physical health, we measured body mass index (BMI), body fat percentage, and heart rate variability. In addition, children’s health-related behaviors (e.g., eating and exercise habits) were assessed using the health promotion behavior scale. A total of 63 students (13 in the experimental and 50 in the control group) who completed both physiological and psychological measures were included in the final analysis. Compared to children in the control group, children in the experimental group showed a significant decrease in their level of hyperactivity (t = -2.01, p = 0.049) and increase in heart rate variability (t = -2.35, p = 0.022). No significant group differences were noted for depression, BMI, body fat percentage, and health promotion behaviors between the two groups. Findings of this study provided preliminary evidence of the effectiveness of a 6-week school-based health promotion program for improving emotional health among school-aged children living in a rural area. Future studies testing the effects of health promotion programs with longer sessions and programs focusing on social-emotional skill development are needed.

关键词： Health Promotion Heart Rate Variability Mental Health School-Aged Children

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SENTINEL NODE DETECTION USING BONE SCAN AS AN ANATOMICAL REFERENCE

SENTINEL NODE DETECTION USING BONE SCAN AS AN ANATOMICAL REF...

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首届中日韩核医学会议

作者： Keon Wook Kang Su kyung Hwang Eun sook Lee Department of Nuclear Medicine National Cancer Center Korea Department of Center for Breast Cancer National Cancer Center Korea Department of Center for Breast Cancer National Cancer Center Korea

＜正＞Objectives: The exact location of sentinel node on lymphoscintigraphy is difficult to find due to poor anatomical landmark. We tested the feasibility of using bone scan as an anatomical reference for lymphoscintigraphy. Methods: Twenty-seven patients with breast cancer have undergone lymphoscintigraphy on the next day of bone scan. About 24 hours after 370 MBq of Tc-99m MDP injection, 5.1±0.9 MBq of Tc-99m antimony sulfide colloid （ASC） were injected and followed by imaging until the sentinel node were visualized. Detection of sentinel node using gamma probe were done after lymphoscintigraphy. Peak counts of background were measured in anterior chest and axilla using gamma probe before injection of Tc-99m ACS. Peak counts of sentinel lymph node were also measured. Results: Sentinel nodes were detected in 24 out of 27 patients. In 3 missing cases, injections were technically failed. Surgeons easily figured out the sentinel nodes both on lymphoscintigraphy and surgical field, and background signals were not affected. The ratio of peak counts between sentinel node and background was 5.0±2.5. This procedure saved the time and efforts of patients to visit hospital for preoperative bone scan prior to admission. Conclusion: Lymphoscintigraphy on the next day after bone scan in patients with breast cancer is a convenient and useful method for locating the sentinel node.

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Comparison of double pants with single pants on satisfaction with colonoscopy

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World Journal of Gastroenterology 2013年第26期19卷 4177-4184页

作者： sook Hee Chung Soo Jung Park Jong Suk Hong Jee Young Hwang Sin Ae Lee kyung Ran Kim Hye Sun Lee Sung Pil Hong Jae Hee Cheon Tae Il Kim Won Ho Kim Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medicine Department of Psychiatry Yonsei University College of Medicine Department of Biostatistics Yonsei University College of Medicine

AIM: To increase satisfaction and diminish anxiety and shame during colonoscopy, we developed novel double pants (NDP) which consist of doubled fabrics with an inner hole. The aim of study was to compare satisfaction, anxiety and shame between NDP and conventional single pants (CSP). METHODS: Total 160 consecutive examinees were randomly divided into NDP and CSP group. Before colonoscopy, questionnaires identifying state and trait anxiety were completed. After colonoscopy, questionnaires for overall satisfaction (Group Health Association of America 9) and pants-specific satisfaction (5-20), state anxiety (20-80), and shame (6-24) were interviewed. RESULTS: Pants-specific satisfaction scores regarding willingness to repeat colonoscopy using same pants (3.3 ± 0.8 vs 2.1 ± 0.9, P < 0.001) and recommendation of same pants to other people (3.3 ± 0.7 vs 2.0 ± 1.0, P < 0.001) were significantly higher in NDP than CSP groups. State anxiety (33.0 ± 7.0 vs 35.4 ± 6.9, P = 0.028) and shame (6.6 ± 1.5 vs 8.1 ± 3.2, P = 0.001) after colonoscopy was lower in NDP group compared with CSP group. CONCLUSION: The NDP contribute to increase satisfaction and decrease anxiety and shame after colonoscopy.

关键词： Pants Colonoscopy Satisfaction Shame Anxiety

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A novel architecture for cargos location and safety in networked RFID

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重庆邮电大学学报（自然科学版） 2007年第3期19卷 386-391页

作者： HUANG Dong-li YUAN Zheng-wu Byeong-Seob You sook-kyung Cho Hae-Young Bae College of Computer Science and Technology Chongqing University of Posts and Telecommunications Chongqing 400065 P. R. China Department of Computer Science and Information Engineering Inha UniversityIncheon 402-751 Korea

Using Networked RFID equipped in warehouse or supermarket distribution, Enterprise information system (EIS) can gather and deal with cargos information. Nevertheless, when cargos are in traffic, the Networked RFID can’t monitor the cargos any more as the products tagged aren’t within range of a reader. This paper proposes a solution framework which combines Networked RFID and GPS tracking, and then equip with this system in container to make the cargos monitored even if the cargos are in traffic. This solution can solve the accurate consignments, position tracking and advanced theft happening through drilling holes in container. In addition, customhouse and checkpoint can get an electronic shipment manifest rapidly and safely when a vehicle gets through a checkpoint.

关键词：射频识别定位全球卫星定位系统货物跟踪企业信息系统海关电子载货单

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A safe haven of SARS-CoV-2 in the environment:Prevalence and potential transmission risks in the effluent,sludge,and biosolids

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Geoscience Frontiers 2022年第6期13卷 302-314页

作者： Bashir Adelodun Pankaj Kumar Golden Odey Fidelis Odedishemi Ajibade Rahmat Gbemisola Ibrahim Saad A.M.Alamri Sulaiman A.Alrumman Ebrahem M.Eid Vinod Kumar Khalid Adeola Adeyemi Ashish Kumar Arya Archana Bachheti Marcos L.S.Oliveira kyung sook Choi Department of Agricultural Civil Engineering Kyungpook National UniversityDaegu 41566South Korea Department of Agricultural and Biosystems Engineering University of IlorinPMB 1515Ilorin 240003Nigeria Agro-ecology and Pollution Research Laboratory Department of Zoology and Environmental ScienceGurukula Kangri(Deemed to be University)Haridwar 249404UttarakhandIndia Department of Civil and Environmental Engineering Federal University of TechnologyPMB 704AkureNigeria Key Laboratory of Environmental Biotechnology Research Centre for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085PR China University of Chinese Academy of Sciences Beijing 100049PR China Kwara State Ministry of Health IlorinKwara StateNigeria Biology Department College of ScienceKing Khalid UniversityAbha 61321Saudi Arabia Botany Department Faculty of ScienceKafrelsheikh UniversityKafr El-Sheikh 33516Egypt Department of Environmental Science Graphic Era(Deemed to be University)Deharadun248002 UttarakhandIndia Department of Civil and Environmental Universidad De La CostaCalle 58#55-66080002 BarranquillaAtlánticoColombia Institute of Agricultural Science&Technology KyungpookNational UniversityDaegu 41566South Korea

The novel coronavirus,SARS-CoV-2,which has caused millions of death globally is recognized to be unstable and recalcitrant in the environment,especially in the way it has been evolving to form new and highly transmissible *** particular concerns are human-environment interactions and the handling and reusing the environmental materials,such as effluents,sludge,or biosolids laden with the SARS-CoV-2 without adequate treatments,thereby suggesting potential transmission and health *** study assesses the prevalence of SARS-CoV-2 RNA in effluents,sludge,and ***,we evaluate the environmental,ecological,and health risks of reusing these environmental materials by wastewater/sludge workers and farmers.A systematic review of literature from the Scopus database resulted in a total of 21 articles(11 for effluents,8 for sludge,and 2 for biosolids)that met the criteria for meta-analysis,which are then subdivided into 30 meta-analyzed *** prevalence of SAR-CoV-2 RNA in effluent and sludge based on random-effect models are 27.51 and 1012.25,respectively,with a 95%CI between 6.14 and 48.89 for the effluent,and 104.78 and 1019.71 for the ***,the prevalence of SARS-CoV-2 RNA in the biosolids based on the fixed-effect model is 30.59,with a 95%CI between 10.10 and *** prevalence of SARS-CoV-2 RNA in environmental materials indicates the inefficiency in some of the treatment systems currently deployed to inactivate and remove the novel virus,which could be a potential health risk concern to vulnerable wastewater workers in particular,and the environmental and ecological issues for the population at *** timely review portends the associated risks in handling and reusing environmental materials without proper and adequate treatments.

关键词： SARS-CoV-2 COVID-19 Environmental materials Health risks Wastewater workers

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