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Association of cannabis use disorder with atrial fibrillation in young men without concomitant tobacco use:Insights from nationwide propensity matched analysis

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World Journal of Experimental Medicine 2024年第3期14卷 64-71页

作者： Bhavin Patel Sumanth Khadke kshitij mahajan Avleen Dhingra Rishika Trivedi Samrath Singh Brar Sakshi Dixit Vaibhav Periwal Shaylika Chauhan Rupak Desai Department of Internal Medicine Trinity Health Oakland HospitalPontiacMI 48341United States Lahey Hospital and Medical Center Division of Cardiovascular MedicineDepartment of MedicineBurlingtonMA 01805United States Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Department of Medicine Dayanand Medical College and HospitalLudhiana 141001PunjabIndia Department of Internal Medicine DHR HealthEdinburgTX 78539United States Department of Medicine Government Medical CollegePatiala 147001PunjabIndia Department of Internal Medicine Geisinger Health SystemWikes-BarrePA 18702United States Independent Researcher Outcomes ResearchAtlantaGA 30079United States

BACKGROUND Recent data are inconclusive regarding the risk of arrhythmias among young cannabis ***,many young adults use both cannabis and tobacco,which could add a residual confounding effect on ***,we studied young men who have cannabis use disorder(CUD)excluding tobacco use disorder(TUD)to understand their independent association with atrial fibrillation(AF)and related *** To study the association of CUD with AF and related *** We used weighted discharge records from National Inpatient Sample(2019)to assess the baseline characteristics and mortality rates for AF-related hospitalizations in young(18-44 years)men in 1:1 propensity-matched CUD+vs CUD-cohorts without *** Propensity matched CUD+and CUD-cohorts consisted of 108495 young men in each *** analysis showed an increased incidence of AF in black population with *** addition,the CUD+cohort had lower rates of hyperlipidemia(6.4%vs 6.9%),hypertension(5.3%vs 6.3%),obesity(9.1%vs 10.9%),alcohol abuse(15.5%vs 16.9%),but had higher rates of anxiety(24.3%vs 18.4%)and chronic obstructive pulmonary disease(COPD)(9.8%vs 9.4%)compared to *** adjustment with covariates including other substance abuse,a non-significant association was found between CUD+cohort and AF related hospitalizations(odd ratio:1.27,95%confidence interval:0.91-1.78,P=0.15).CONCLUSION Among hospitalized young men,the CUD+cohort had a higher prevalence of anxiety and COPD,and slightly higher proportion of black *** there were higher odds of AF hospitalizations in CUD+cohort without TUD,the association was statistically *** subgroup analysis showed higher rates of AF in black ***-scale prospective studies are required to evaluate long-term effects of CUD on AF risk and prognosis without TUD and concomitant substance abuse.

关键词： Cannabis Marijuana Atrial fibrillation Tobacco use disorder Original research Smoking

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Tubularized incised plateurethroplasty and grafted tubularized incised plate urethroplasty: systematic review, metaanalysis and trial sequential analysis

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World Journal of Pediatric Surgery 2024年第1期7卷 10-19页

作者： Nitinkumar Borkar Charu Tiwari Abhijit Nair Debajyoti Mohanty C K Sinha Jai Kumar mahajan Paediatric Surgery All India Institute of Medical Sciences-RaipurRaipurChhattisgardhIndia Department of Anaesthesiology Ibra HospitalbraOman General Surgery All India Institute of Medical Sciences-RaipurRaipurChhattisgardhIndia Paediatric Surgery St George's University Hospitals NHS Foundation TrustLondonUK Pediatric Surgery PGIMERChandigarhIndia

Background Hypospadias is one of the most common genital birth *** are around 300 various techniques available for the repair of *** study aims to compare the reported outcomes of Tubularized incised plate urethroplasty(TIP)and Grafted TIP(GTIP)repair in children undergoing primary *** This meta-analysisadhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines,and we framed our research question using the population,intervention,control and outcomes *** conducted comprehensive electronic searches across various databases,employing a Boolean search strategy with predefined search *** randomized controlled trials(RCTs)were included for quantitative *** Totally,10 RCTs met our inclusion criteria for quantitative *** results indicated that urethrocutaneous fistula,glans dehiscence,and stricture rates were comparable between the two *** incidence of meatal stenosis was found to be significantly lower in the GTIP group with a relative risk(RR)of 0.32(95%confidence interval(Cl)0.15 to 0.67).Conclusion The coucomes UCF,glans dehiscence,and stricture rates were comparable between the two ***,the incidence of meatal stenosis was found to be significantly lower in the grafted TIP *** terms of operative time,our quantitative synthesis demonstrated that the TIP group had a shorter operative time than the GTIP group with significant heterogeneity.

关键词： plate grafted analysis

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Typhoon-and pollution-driven enhancement of reactive bromine in the mid-latitude marine boundary layer

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National Science Review 2024年第4期11卷 93-101页

作者： Shanshan Wang Qinyi Li Ruifeng Zhang Anoop Sharad mahajan Swaleha Inamdar Nuria Benavent Sanbao Zhang Ruibin Xue Jian Zhu Chenji Jin Yan Zhang Xiao Fu Alba Badia Rafael P.Fernandez Carlos A.Cuevas Tao Wang Bin Zhou Alfonso Saiz-Lopez Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3) Department of Environmental Science and Engineering Fudan University Institute of Eco-Chongming(IEC) Department of Atmospheric Chemistry and Climate Institute of Physical Chemistry Blas CabreraCSIC Department of Civil and Environmental Engineering The Hong Kong Polytechnic University Environment Research Institute Shandong University Centre for Climate Change Research Indian Institute of Tropical MeteorologyMinistry of Earth Sciences Department of Chemistry University of Colorado Boulder Institute of Environment and Ecology Tsinghua Shenzhen International Graduate SchoolTsinghua University Sostenipra Research Group Institute of Environmental Science and Technology(ICTA)Universitat Autonoma de Barcelona(UAB) Institute for Interdisciplinary Science (ICB) National Research Council (CONICET)

Tropospheric reactive bromine is important for atmospheric chemistry,regional air pollution,and global *** studies have reported measurements of atmospheric reactive bromine species in different environments,and proposed their main sources,***-salt aerosol（SSA）,oceanic biogenic activity,polar snow/ice,and *** and other strong cyclonic activities（***） induce abrupt changes in different earth system processes,causing widespread destructive ***,the role of typhoons in regulating reactive bromine abundance and sources remains ***,we report field observations of bromine oxide（BrO）,a critical indicator of reactive bromine,on the Huaniao Island（HNI）in the East China Sea in July *** observed high levels of BrO below 500 m with a daytime average of9.7±4.2 pptv and a peak value of ～26 pptv under the influence of a *** field measurements,supported by model simulations,suggest that the typhoon-induced drastic increase in wind speed amplifies the emission of SSA,significantly enhancing the activation of reactive bromine from SSA *** also detected enhanced BrO mixing ratios under high NOxconditions（ppbv level） suggesting a potential pollution-induced mechanism of bromine release from *** elevated levels of atmospheric bromine noticeably increase ozone destruction by as much as ～40% across the East China *** the high frequency of cyclonic activity in the northern hemisphere,reactive bromine chemistry is expected to play a more important role than previously thought in affecting coastal air quality and atmospheric oxidation *** suggest that models need to consider the hitherto overlooked typhoon-and pollution-mediated increase in reactive bromine levels when assessing the synergic effects of cyclonic activities on the earth system.

关键词： reactive bromine atmospheric chemistry marine boundary layer atmospheric oxidation capacity marine emission

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Incidence of urinary incontinence following endoscopic laser enucleation of the prostate by en-bloc and non-en-bloc techniques:a multicenter,real-world experience of 5068 patients

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Asian Journal of Andrology 2024年第3期26卷 233-238页

作者： Daniele Castellani Vineet Gauhar Khi Yung Fong Mario Sofer Moisés Rodríguez Socarrás Azimdjon N Tursunkulov Lie Kwok Ying Sarvajit Biligere Ho Yee Tiong Dean Elterman Abhay mahajan Mark Taratkin Sorokin Nikolai Ivanovich Tanuj Pal Bhatia Dmitry Enikeev Nariman Gadzhiev Mohammed Taif Bendigeri Jeremy Yuen-Chun Teoh Marco Dellabella Fernando Gómez Sancha Bhaskar Kumar Somani Thomas Reinhard William Herrmann Urology Unit IRCCS INRCAAncona 60127Italy Urology Unit Marche University HospitalLe Marche Polytechnic UniversityAncona 60126Italy Department of Urology Ng Teng Fong General HospitalSingapore 609606Singapore Yong Loo Lin School of Medicine National University of SingaporeSingapore 117597Singapore Department of Urology Tel Aviv Sourasky Medical CenterAffiliated to the Sackler School of MedicineTel Aviv UniversityTel Aviv 6423906Israel Department of Urology and Robotic Surgery ICUA-Clínica CEMTROMadrid 28701Spain Urology Division Akfa Medline HospitalTashkent 100211Uzbekistan Advanced Urology Gleneagles HospitalSingapore 258499Singapore Department of Urology National University HospitalSingapore 119228Singapore Divisionof Urology Department of SurgeryUniversity of TorontoOntarioToronto M5G 2C4Canada Department of Urology Mahatma Gandhi Mission’s Medical College and HospitalAurangabad 431003India Institute for Urology and Reproductive Health Sechenov UniversityMoscow119435Russian Federation Department of Urologyand Andrology Lomonosov Moscow State UniversityMoscow 119992Russian Federation Department of Urology Sarvodaya Hospital and Research CentreFaridabadHaryana 121006India Department of Urology Medical University of ViennaVienna 1090Austria Department of Urology Saint-Petersburg State University HospitalSaint-Petersburg 199034Russian Federation Department of Urology Asian Institute of Nephrology and UrologyHyderabad 500082India S.H.Ho UrologyCentre Department of SurgeryFaculty of MedicineThe Chinese University of Hong KongHong Kong 96H2+Q9China Department of Urology University Hospitals Southampton NHS TrustSouthampton SO166YDUnited Kingdom Department of Urology Cantonal Hospital Thurgau AGFraunfeld 8500Switzerland

We aim to evaluate the incidence of incontinence following laser endoscopic enucleation of the prostate(EEP)comparing en-bloc(Group 1)versus 2-lobe/3-lobe techniques(Group 2).We performed a retrospective review of patients undergoing EEP for benign prostaticenlargement in 12 centers between January 2020 and January *** were presented as median and interquartile range(IQR).Univariable and multivariable logistic regression analysis was performed to evaluate factors associated with stress urinary incontinence(SUI)and mixed urinary incontinence(MUI).There were 1711 patients in Group 1 and 3357 patients in Group *** in Group 2were significantly younger(68[62–73]years vs 69[63–74]years,P=0.002).Median(interquartile range)prostate volume(PV)wassimilar between the groups(70[52–92]ml in Group 1 vs 70[54–90]ml in Group 2,P=0.774).There was no difference in preoperativeInternational Prostate Symptom Score,quality of life,or maximum flow ***,morcellation,and total surgical time weresignificantly shorter in Group *** 1 month,overall incontinence rate was 6.3%in Group 1 versus 5.3%in Group 2(P=0.12),and urge incontinence was significantly higher in Group 1(55.1%vs 37.3%in Group 2,P<0.001).After 3 months,the overall rate ofincontinence was 1.7%in Group 1 versus 2.3%in Group 2(P=0.06),and SUI was significantly higher in Group 2(55.6%vs 24.1%in Group 1,P=0.002).At multivariable analysis,PV and IPSS were factors significantly associated with higher odds of transient SUI/***,surgical time,and no early apical release technique were factors associated with higher odds of persistent SUI/MUI.

关键词： benign prostatic hyperplasia en-bloc enucleation endoscopic enucleation of the prostate laser therapy stress urinaryincontinence urge urinary incontinence

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掠夺性放贷应用程序加剧网络诈骗

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商业周刊（中文版） 2024年第4期 16-18页

作者： Catherine Ngai Fathiya Dahrul Pathom Sangwongwanich Shruti mahajan 赵萌萌(译) 不详

●基于贷款应用程序的骗局愈发猖獗,而这些犯罪行动背后的幕后黑手正在适应防范措施麻烦往往从社交媒体广告开始。比如Facebook或Instagram上的那些广告:20分钟内即可获得500美元的个人贷款。无需任何文件,只要下载这个应用程序。潜在... 详细信息

●基于贷款应用程序的骗局愈发猖獗,而这些犯罪行动背后的幕后黑手正在适应防范措施麻烦往往从社交媒体广告开始。比如Facebook或Instagram上的那些广告:20分钟内即可获得500美元的个人贷款。无需任何文件,只要下载这个应用程序。潜在的借款人照做之后,他们就会交出手机通讯录和相册的访问权限。第二天,他们的朋友、家人和雇主就会收到电子邮件,称受害者指认他们为担保人,他们需要立即支付一大笔钱。

关键词：应用程序网络诈骗电子邮件访问权限手机通讯录 Facebook 借款人个人贷款

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Noble gases,nitrogen and cosmic ray exposure age of the Sulagiri chondrite

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Geoscience Frontiers 2017年第1期8卷 205-210页

作者： Ramakant R.mahajan Physical Research Laboratory Ahmedabad380009India

The Sulagiri meteorite fell in India on 12 September 2008,LL6 chondrite class is the largest among all the Indian *** compositions of noble gases（He,Ne,Ar,Kr and Xe） and nitrogen in the Sulagiri meteorite and cosmic ray exposure history are *** cosmogenic（22Ne/21Ne）c ratio is consistent with irradiation in a large *** noble gases indicate that Sulagiri has a 4πcosmic-ray exposure（CRE） age of 27.9 ± 3.4 Ma and is a member of the peak of CRE age distribution of IX *** 4He and 40Ar concentrations in Sulagiri yields the radiogenic ages as 2.29 and4.56 Ca,indicating the loss of He from the *** and krypton are mixture of Q and spallogenic components.

关键词： Noble gases Nitrogen Cosmic ray exposure age Meteorite Trapped gases

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Variation in Antioxidants, Bioactive Compounds and Antioxidant Capacity in Germinated and Ungerminated Grains of Ten Rice Cultivars

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Rice science 2017年第6期24卷 349-359页

作者： Maninder KAUR Bavita ASTHIR Gulshan mahajan Department of Biochemistry Punjab Agricultural University Ludhiana Punjab 141004 India Department of Plant Breeding and Genetics Punjab Agricultural University Ludhiana Punjab 141004 India

Present study was conducted to characterise ten rice(Oryza sativa L.) cultivars viz. IET-23466, Dhan-201, IET-23448, MAS-946, IET-23445, IET-23463, IET-23455, PR-123, PR-115 and IET-23449 based on antioxidants(total phenolics, flavonols and tannins), bioactive compounds(phytic acid, gamma amino butyric acid, tocopherol and reduced ascorbate) and antioxidant activity(1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, hydroxyl radical scavenging activity, free radical antioxidant power and total reducing power) with an aim to identify cultivars containing higher health promoting components after germination. Three cultivars IET-23466, IET-23463 and PR-123 performed better as revealed by higher level of antioxidants, bioactive compounds and antioxidant activity before and after germination. Three cultivars MAS-946, IET-23445 and IET-23449 had moderate level of antioxidants, bioactive compounds and antioxidant activity. Four cultivars Dhan-201, IET-23448, IET-23455 and PR-115 performed intermediately. Strong positive correlation was observed among total phenolics and the antioxidant activity. Phytic acid was found to be negatively correlated to the antioxidant activity. Our results highlighted that cultivars IET-23466, IET-23463 and PR-123 hold great potential after germination and would open up a useful opportunity for the functional food industry, and consumption of these cultivars after germination would afford health benefits to consumers since they contain higher level of antioxidants.

关键词： antioxidant activity bioactive compound flavonol phytic acid total phenolic rice germination

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Homeostasis of T Cell Diversity

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Cellular & Molecular Immunology 2005年第1期2卷 1-10页

作者： VinayS.mahajan IlyaB.Leskov Center for Cancer Research and Department of Biology Massachusetts Institute of TechnologyCambridgeMA 02139USA.

T cell homeostasis commonly refers to the maintenance of relatively stable T cell numbers in the peripheral lymphoid *** the large numbers of T cells in the periphery,T cells exhibit structural diversity,i.e.,the expression of a diverse repertoire of T cell receptors(TCRs),and functional diversity,i.e.,the presence of T cells at nave,effector,and memory developmental *** the homeostasis of T cell numbers has been extensively studied,investigation of the mechanisms underlying the maintenance of structural and functional diversity of T ceils is still at an early *** fundamental feature throughout T cell development is the interaction between the TCR and either self or foreign peptides in association with MHC *** this review,we present evidence showing that homeostasis of T cell number and diversity is mediated through competition for limiting resources. The number of T cells is maintained through competition for limiting cytokines,whereas the diversity of T cells is maintained by competition for self-peptide-MHC *** other words,diversity of the self-peptide repertoire limits the structural(TCR)diversity of a T cell *** speculate that cognate low affinity self-peptides, acting as weak agonists and antagonists,regulate the homeostasis of T cell diversity whereas non-cognate or null peptides which are extremely abundant for any given TCR,may contribute to the homeostasis of T cell number by providing survival ***,self-peptides and cytokines may form specialized niches for the regulation of T cell *** & Molecular Immunology.2005;2(1):1-10.

关键词： lymphocyte homeostasis lymphocyte compartment lymphocyte diversity lymphopenia-induced proliferation self-peptide cytokine

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Continuous Mixed p-norm Control Scheme with Reweighted L_(0) norm Variable Step Size for Mitigating Power Quality Problems of Grid Coupled Solar PV Systems

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CSEE Journal of Power and Energy Systems 2023年第4期9卷 1394-1404页

作者： Pallavi Verma Avdhesh Kumar Rachana Garg Priya mahajan Delhi technological university DelhiDelhi 110085India.

In this paper,the performance of a two-stage three-phase grid coupled solar photovoltaic generating system(SPVGS)is analyzed by using a novel reweighted Lo norm variable step size continuous mixed p-norm(RLo-VSSCMPN)of a voltage source inverter(VSI)control *** efficacy of the system is determined by considering unbalanced grid voltage,DC offset,voltage sag and swell,unbalanced load and variations in solar ***-VSSCMPN is used for inverter control and it ex-tracts fundamental components of load current for generating the reference grid current with a faster convergence rate and lesser steady state *** the proposed control,harmonics in the grid current follows the IEEE-519 norm and the performance is also satisfactory under varying environmental/load *** power generated from SPvGS is transferred optimally using a DC-DC boost converter utilizing the incremental conductance(INC)maximum power point *** proposed system is simulated using MATLAB/Simulink 2018a and test results are verified experimentally using dSPACE1202 in the laboratory to ensure the validity of a novel proposed robust *** Terms-INC maximum power point tracker,power quality,reweighted LoVSSCMPN algorithm,solar PV generating system,total harmonic distortion,voltage source inverter.

关键词： INC maximum power point tracker power quality reweighted LoVSSCMPN algorithm solar PV generating system total harmonic distortion voltage source inverter.

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Dynamical Casimir effect in superradiant light scattering by Bose Einstein condensate in an optomechanical cavity

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Chinese Physics B 2014年第2期23卷 151-160页

作者： Sonam mahajan Neha Aggarwal Aranya B Bhattacherjee ManMohan Department of Physics and Astrophysics University of Delhi Department of Physics ARSD CollegeUniversity of Delhi (South Campus) School of Physical Sciences Jawaharlal Nehru University

We investigate the effects of dynamical Casimir effect in superradiant light scattering by Bose-Einstein condensate in an optomechanical cavity. The system is studied using both classical and quantized mirror motions. The cavity frequency is harmonically modulated in time for both the cases. The main quantity of interest is the number of intracavity scattered photons. The system has been investigated under the weak and strong modulations. It has been observed that the amplitude of the scattered photons is more for the classical mirror motion than the quantized mirror motion. Also, initially, the amplitude of scattered photons is high for lower modulation amplitude than higher modulation amplitude. We also found that the behavior of the plots are similar under strong and weak modulations for the quantized mirror motion.

关键词： Bose-Einstein condensates dynamical Casimir effect superradiant light scattering optomechan- ical cavity

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