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The enjoyment of music : an introduction to perceptive listening Joseph Machlis, kristine Forney. 9th ed.; chronological.

2003年

作者： Joseph Machlis kristine Forney

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妙趣童颜 kristine和她的清新儿童照

2003年

作者： Joseph Machlis kristine Forney.

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人像摄影 2013年第7期 92-96页

作者： kristine Ovsepyan Carol

正作为妈妈,kristine对她的儿子有着无尽的兴趣和热情,她说:"我几乎想拍下所有关于他的一切,时光流逝得如此之快,我想这是唯一能让我记住这些珍贵瞬间的方式。"她也把这种热情带入到自己作为商业儿童摄影师的角色中。

关键词：摄影师儿童照片快门速度感光度相机记录画面风格母亲

’Emulsion locks’ for the containment of hydrocarbons during surfactant flushing

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Journal of Environmental Sciences 2020年第4期32卷 98-109页

作者： kristine Lamont Alejandro GMarangoni Erica Pensini University of Guelph School of Engineering50 Stone Road EastGwelph ONNIG 2W1Canada University of Guelph Food Science Department50 Stone Road EastGuelph ONNIG 2WlCanada

Reversible double water in oil in water(W/O/W)emulsions were developed to contain subsurface hydrocarbon spills during their remediation using surfactant *** emulsions were prepared by emulsifying CaCl2 solutions in canola oil,and subsequently by emulsifying the W/O emulsions in aqueous sodium alginate *** formation of double emulsions was confirmed with confocal and optical *** double emulsions reversed and gelled when mixed with the surfactants sodium dodecyl sulfate(SDS)and cocamidopropyl betaine(CPB).Gels can act as’emulsion locks’to prevent spreading of the hydrocarbon plume from the areas treated with surfactant flushing,as shown in sand column *** rheology was used to quantify the viscoelastic moduli increase(gelation)upon mixing the double emulsion with SDS and *** was more effective than CPB in gelling the double *** and SDS could adsorb at the interface between water and model hydrocarbons(toluene and motor oil),lowering the interfacial tension and rigidifying the interface(as shown with a Langmuir trough).Bottle tests and optical microscopy showed that SDS and CPB produced W/O and O/W emulsions,with either toluene or motor oil and *** emulsification of motor oil and toluene in water with SDS and CPB facilitated their flow through sand columns and their *** recovery from sand columns was quantitated using Gas-Chromatography MassSpectroscopy(GC-MS).The data show that SDS and CPB can be used both for surfactant flushing and to trigger the gelation of’emulsion locks’.Ethanol also gelled the emulsions at100 mL/L.

关键词： Remediation Emulsion Hydrocarbons Surfactant Rheology Langmuir trough

Geology without national boundaries The 1 ： 5 Million International Geological Map of Europe and Adjacent Areas IGME 5000

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Episodes 2006年第1期29卷 39-42页

作者： kristine Asch Federal Institute for Geosciences and Natural Resources （BGR）GERMANY

The International Geological Map of Europe and Adjacent Areas （IGME 5000） is a major European geological GIS project being managed and implemented by the German Geological Survey （Federal Institute for Geosciences and Natural Resources, BGR） under the umbrella of the Commission for the Geological Map of the World （CGMW）. It is a collaborative European project that to date involves 48 Geological Surveys and is supported by a network of scientific advisors. The original aims of the project have now been achieved： to develop a Geographic Information System （GIS） containing up-to-date harmonised lithological and geochronological data of Europe, and to print a geological map （Figure 1） of the preQuaternary on-shore and, for the first time at this scale, off-shore areas of Europe （see Asch, 2003, for a full account.）

关键词：地质图地理信息系统国家边界地质勘测 GIS

A FACTOR(S) PRODUCED BY SERTOLI CELLS STIMULATES ANDROGEN BIOSYNTHESIS BY LEYDIG CELLS IN NEONATAL RATS

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Science China Chemistry 1988年第07期31卷 818-827页

作者：刘以训,kristine D. DAHL Laboratory of Reproductive Biology Institute of Zoology Academia Sinica Beijing Department of Reproductive Medicine M-025 University of California San Diego La Jolla CA 92093 USA

Using a coculture system, we have studied the local action of Sertoli cells on Leydig cell function. The results show that （ⅰ） both LH and FSH have equal potency to stimulate testosterone biosynthesis by fetal and neonatal testicular cells in an age-dependent manner, the maximum stimulation is observed between D3and D5. （ⅱ） An FSH-dependent factor（s） secreted by Sertoli cells increases the basal and/or LH-stimulated Leydig cell androgen production. （ⅲ） The Sertoli cell-stimulating factor（s） is not a steroid or other small molecule, but a heat-labile peptide.

关键词： Leydig cells Sertofi cells coculture factor testosterone production.

Uniformity in premating reproductive isolation along an intraspecific cline

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Current Zoology 2018年第5期64卷 641-652页

作者： Jeanne Marie ROBERTSON Roman NAVA Andrds VEGA kristine KAISER Department of Biology California State University Northridge 18111 Nordhoff Street Northridge CA 91330-8303 USA Naturel History Museum of Los Angeles County 900 Exposition Boulevard Los Angeles CA 90007 USA Department of Biology San Diego State University 5500 Campanile Drive San Diego CA 92116 USA AMBICOR 400 E. 75 S. 75 E. de la Municipalidad de Tibas Tibas Costa Rica

Premating reproductive isolation （RI） may reduce gene flow across populations that have differentiated in traits important for mate choice. Examining RI across genetic and phenotypic clines can inform the fundamental evolutionary processes that underlie population and lineage differentiation. We conducted female mate-choice studies across an intraspecific red-eyed treefrog cline in Costa Rica and Panama with 2 specific aims：（1） to characterize RI across the cline and examine the relationship between premating RI and genetic and phenotypic distance and （2） to evaluate our results within a broader evolutionary and taxonomic perspective through examination of other RI studies. We found that female red-eyed treefrogs prefer local males relative to non-local males, indicating that some premating RI has evolved in this system, but that preference strength is not associated with phenotypic or geographic distance. Our analysis of 65 other studies revealed no clear pattern between the strength of RI and geographic distribution （allopatry, parapatry, cline） or phenotypic distance, but revealed extreme variation and overlap in levels of intra- and interspecific levels of RI. This work contributes to a growing body of literature that examines intraspecific RI across a cline to understand the selective processes that shape evolutionary patterns at the earliest stages of divergence.

关键词： advertisement call anuran color pattern courtship signals mate choice.

Vascularization in interconnected 3D printed Ti-6Al-4V foams with hydrogel matrix for biomedical bone replacement implants

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Science China Materials 2018年第4期61卷 565-578页

作者： Victor L.Correa kristine M.Garza Lawrence E.Murr Department of Metallurgical Materials and Biomedical Engineering University of Texas at El Paso Department of Biological Sciences University of Texas at El Paso

Vascularization on newly implanted metal orthopedic implants has remained a challenge in the field of tissue engineering. To address this challenge, in this research,an interconnected foam structure of Ti-6 Al-4 V was microfabricated by electron beam melting(EBM) technique. The foam in question has a density of 1.77 g cm-3 with 60% porosity and a tensile strength of 18 GPa. An extracellular matrix based hydrogel was added as an aqueous matrix to the *** mimetic stress has been closely related to many wound healing biomedical applications as it increases survival and proliferation molecular signals. To that end, increased expression of hypoxia-inducible factor-1α(Hif-1α) and vascular endothelial growth factor(VEGF) in the aqueous hydrogel matrix was achieved by the addition of a hypoxia mimetic deferoxamine mesylate(DFM). In this study, the formation of an endothelial network was achieved in a hydrogel matrix in the presence of the before mentioned 3 D printed metal foam. Cellular viability, fluorescent microscopy and scanning electron microscopy imaging analysis demonstrate that pre-osteoblasts undergo proliferation and also attach efficiently to the foam when exposed to DFM. Human umbilical vascular endothelial cells(HUVECs) were grown in an extracellular matrix-like 3 D hydrogel and a hypoxia-like stress was achieved. This research demonstrates that pre-osteoblast cells undergo cell differentiation and increase the production of hydroxyapatite on exposure to the hypoxia mimetic molecule. This proposed approach encompasses an ideal prototype for a completely living implanted structure for future orthopedic implants.

关键词： Ti-6Al-4V electron beam melting angiogenesis deferoxamine mesylate hydrogel vascularization

PNPLA8是调控三阴性乳腺癌磷脂代谢并促进肿瘤增殖和转移的关键分子（英文）

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PNPLA8是调控三阴性乳腺癌磷脂代谢并促进肿瘤增殖和转移的关键分...

3D finite element method （FEM） simulation of groundwater flow during backward erosion piping

2024中国肿瘤标志物学术大会暨CACA整合肿瘤学高峰论坛暨第十七届肿瘤标志物青年科学家论坛暨中国肿瘤标志物产业创新大会

作者：谭哲琼 Pragney Deme Keerti Boyapati Annet A.M.Duivenvoorden Ron M.A.Heeren Caitlin M.Tressler Norman James Haughey kristine Glunde

Background Triple-negative breast cancer(TNBC) is the most aggressive breast cancer subtype and leads to the poorest patient outcomes despite surgery and chemotherapy treatment. Exploring new molecular mechanisms of TNBC that could lead to the development of novel molecular targets are critically important for improving therapeutic options for treating *** We sought to identify novel therapeutic targets in TNBC by combining genomic and functional studies with lipidomic analysis, which included mechanistic studies to elucidate the pathways that tie lipid profile to critical cancer cell properties. Our studies were performed in a large panel of human breast cancer cell lines and patient *** Comprehensive lipid profiling revealed that phospholipid metabolism is reprogrammed in TNBC cells. We discovered that patatin-like phospholipase domain-containing lipase 8(PNPLA8)is overexpressed in TNBC cell lines and tissues from breast cancer patients. Silencing of PNPLA8disrupted phospholipid metabolic reprogramming in TNBC, particularly affecting the levels of phosphatidylglycerol(PG), phosphatidylcholine(PC), lysophosphatidylcholine(LPC) and glycerophosphocholine(GPC). We showed that PNPLA8 is essential in regulating cell viability,migration and antioxidation in TNBC cells and promoted arachidonic acid and eicosanoid production, which in turn activated PI3K/Akt/Gsk3β and MAPK *** Our study highlights PNPLA8 as key regulator of phospholipid metabolic reprogramming and malignant phenotypes in TNBC, which could be further developed as a novel molecular treatment target.

关键词： PNPLA8 Breast cancer Triple negative Phospholipid Metabolism reprogramming Eicosanoids Migration Invasion Proliferation

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Frontiers of Structural and Civil Engineering 2014年第2期8卷 160-166页

作者： kristine VANDENBOER Vera van BEEK Adam BEZUIJEN Department of Civil Engineering Ghent University Ghent 9000 Belgium Deltares Delft 2628 Netherlands Section Geoengineering Delft University of Technology Delft 2628 Netherlands

Backward erosion piping is an important failure mechanism for cohesive water retaining structures which are founded on a sandy aquifer. At present, the prediction models for safety assessment are often based on 2D assumptions. In this work, a 3D numerical approach of the groundwater flow leading to the erosion mechanism of backward erosion piping is presented and discussed. Comparison of the 2D and 3D numerical results explicitly demonstrates the inherent 3D nature of the piping phenomenon. In addition, the influence of the seepage length is investigated and discussed for both piping initiation and piping progression. The results clearly indicate the superiority of the presented 3D numerical model compared to the established 2D approach. Moreover, the 3D numerical results enable a better understanding of the complex physical mechanism involved in backward erosion piping and thus can lead to a significant improvement in the safety assessment of water retaining structures.

关键词： backward erosion piping groundwater flow 3D finite element method (FEM)