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Open Journal of Gastroenterology 2018年第12期8卷 455-462页

作者： Ollo Roland Some Ida Aida Tankoano mali koura Valentin Konségré Damien Konkobo Jérome Koulidiaty Institut Supérieur des Sciences de la Sante of Nazi Boni University Bobo-DioulassoBurkina Faso Universite Cheick Anta Diop Hospital Aristide Le DantecDakarSénégal Universite Ouaga 1 Joseph Ki Zerbo OuagadougouBurkina Faso

Introduction: Gastrointestinal stromal tumor (GIST) is the most common non-epithelial, mesenchymal tumor of the digestive tract. Targeted therapy has improved the prognosis but the diagnosis must be accurate before using the existing drugs. Aim: To report the diagnostic difficulty in our context through the clinical polymorphism and define the position of targeted therapy in the management of GIST metastatic stomach. Casuistry: We report 3 cases of gastric GIST with liver metastasis in different circumstances of discovery. Patients were 21, 45, and 73 years old. Discovery circumstances were respectively digestive hemorrhage, severe clinical anemia, abdominal tumor and gastric tumor. There was hepatic metastasis in the three cases. The three patients received Imatinib treatment, adjuvant treatment for the first two cases, and neo-adjuvant treatment for the third case, with a very good clinical response and CT response on metastases. Conclusion: Because of their rarity, GISTs are often difficult to diagnose, and necessarily require immunohistochemistry which is not available in our work context. The effectiveness of targeted therapy even on metastasis needs a rigorous diagnostic approach to improve patient survival.

关键词： Gastric Stromal Tumors Metastases Imatinib Surgery Bobo Dioulasso

Sociodemographic Factors of Alcohol Consumption in a Population of Hospitalized Patients in Ouagadougou (Burkina Faso)

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Open Journal of Gastroenterology 2017年第3期7卷 96-104页

作者： Zanga Damien Ouattara mali koura Abdel Karim Serme Kounpilélimé Sosthène Somda Aboubacar Coulibaly Steve Léonce Zoungrana Appolinaire Sawadogo Hepato-Gastroenterology Unit CHU Ouahigouya UFR/SDS CUP Ouahigouya Burkina Faso Hepato-Gastroenterology Unit CHU-SS Bobo Dioulasso Burkina Faso Hepato-Gastroenterology Unit CHU-YO Ouagadougou Burkina Faso

The prevalence of excessive alcohol consumption is high in our context. The fight against this scourge requires accurate identification of sociodemographic factors for a better communication strategy. Objective: To determine the sociodemographic factors associated with alcohol consumption in a population of hospitalized patients. Methods: A cross-sectional study was conducted during two months in 14 hospital departments of the University Hospital CHU-Yalgado Ouédraogo (CHUYO) in Ouagadougou, by interview and document review. All patients hospitalized for less than a year, aged 18 at least and consenting were included. Excessive alcohol consumption was defined as consumption ≥210 g/week in men and 140 g/week in women according to WHO, a score ≥8 in men and in women ≥7 by AUDIT Questionnaire, a score ≥2 according to the DETA questionnaire. Socio-demographic factors as age, sex, religion, educational level, marital status, occupation and salary status were filled for all patients. Results: A total of 391 patients were included. The average age was 44 ± 16.26 years and the sex ratio of 1.34. Among them, 135 (34.53%) were consumers of alcohol. The prevalence of excessive consumption ranged from 7.92% to 10.49%. A statistically significant relationship was found between alcohol consumption and sex (p 0.03), religion (p 0.01) and education level (p 0.01). On the contrary, no significant relationship was found between alcohol consumption, age, marital status and occupation. The salary status “employee” appears to promote the consumption of alcohol by some tools. Conclusion: The excessive consumption of alcohol is common in our population especially by educated men of non-Muslim religion. This hypothesis should be corroborated in a study within the general population to better set control strategies against this scourge.

关键词： Alcohol Sociodemographic Factors

Prevalence and Factors Associated with Alcohol Consumption in Urban Schools in Burkina Faso

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Open Journal of Gastroenterology 2017年第6期7卷 187-196页

作者： mali koura Ivlabehire Bertrand Méda Zanga Damien Ouattara Couna Christiane Béré Somé Kounpilélimé Sosthène Somda Aboubacar Coulibaly Smaila Ouédraogo Appolinaire Sawadogo Hepato-Gastroenterology Unit CHU-SS Bobo-Dioulasso Burkina Faso IRSS/CNRST Ouagadougou Burkina Faso Hepato-Gastroenterology Unit CHU Ouahigouya Burkina Faso Hepato-Gastroenterology Unit CHU-YO Ouagadougou Burkina Faso Public Health Department CHU-YO Ouagadougou Burkina Faso

Background: In 2005, the World Health Assembly asked member states to develop effective strategies and programs to reduce the negative consequences of harmful use of alcohol. To develop effective policies, we must already understand the phenomenon of alcohol consumption. But in Francophone west Africa, there are very few studies on the prevalence of alcohol, consumption patterns and factors associated with this consumption. The objectives of this study were to estimate the prevalence of alcohol use in schools in Burkina Faso and to identify socio-demographic factors associated with episodes of “heavy drinking”. Method: A cross-sectional study was conducted in October 2013 in six secondary schools of Bobo-Dioulasso. Three hundred and sixty-two students randomly drawn by stratified cluster sampling were interviewed by using a self-administered questionnaire adapted from the model ESPAD and WHO AUDIT questionnaire. HED (Heavy Episodic Drinking) was defined as consuming at least six local measures of alcoholic beverages around the 30 days prior investigation. The search for factors was performed using logistic regression and estimating standard errors were adjusted for clustering data. Results: The prevalence of experimentation of alcohol was estimated to 45.6% [CI 95% = 40.4 - 50.7]. This prevalence was reduced to 34.8% [CI 95% = 29.9 - 39.7], 24.3% [CI 95% = 19.9 - 28.7] and 18% [CI 95% = 14 - 21.9] if one considered the use of alcohol at least once respectively in the 12 months, 30 days and 7 days before the survey. The prevalence of HED was 16% [CI95% = 12.2 - 19.8]. Independent factors associated with the HED were alcohol use by parents or friends and father’s occupation. Episodes of “heavy drinking” were 8.3 (CI 95% = 4.9 - 14) and 2.8 (CI 95% = 1.3 - 5.8) respectively more frequent among students whose parents and friends were drinking. Neither religion nor sex nor age was not statistically associated with HED. Conclusion: This study confirms the high prevalence

关键词： Prevalence Heavy Drinking School Associated Factors

Viral Hepatitis B under Tenofovir in Ouagadougou (Burkina Faso)

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Open Journal of Gastroenterology 2021年第8期11卷 141-150页

作者： Soudré Sandrine Marie-Odile Bobilwindé Napon Fahosiata Zoungrana Steve Léonce Ouattara Zanga Damien koura mali Guingané Nanelin Alice Somda Sosthène Coulibaly Aboubacar Beni Da Nathalie Salou Rodrigue Bougouma Alain Sombié Arsène Roger Hepato-Gastroenterology Unit of the University Hospital Tengandogo Burkina Faso Africa Hepato-Gastroenterology Unit of the University Hospital Ouahigouya Burkina Faso Africa Gastroenterology Service of the University Hospital Souro Sanou Bobo-Dioulasso Burkina Faso Africa Gastroenterology Service of the University Hospital Bogodogo Ouagadougou Burkina Faso Africa Gastroenterology Service of the University Hospital Yalgado Ouédraogo Ouagadougou Burkina Faso Africa

Introduction: The treatment of viral hepatitis B is based on nucleotide analogs(s). In Burkina Faso, tenofovir is the most widely used because of its effectiveness and cost. The aim of this study was to describe viral hepatitis B under tenofovir in Ouagadougou. Material and Method: This was a longitudinal study, carried out in the outpatient department of the University Hospital of Tengandogo from May 1, 2013 to September 31, 2020, i.e. a period of seven (07) years and five (05) months. All patients with chronic hepatitis B virus who had been taking tenofovir for at least one year were included in the study. Cases of hepatocellular carcinoma and co-infections with hepatitis D, C and human immunodeficiency viruses were excluded from the study. Results: Of 321 patients with hepatitis B, 120 were on tenofovir and 34 were included in our study. These were 24 men and 10 women with an average age of 39 years. Hepatitis B was most often discovered following systematic or voluntary screening (44.1%) or pain in the right hypochondrium (23.5%). The mean initial viral load was 7.9 log. Ten patients had moderate compliance and four were non-compliant. No side effects were reported in 91.3% of cases. The virologic response was complete in 72.7% of patients after six months. Nine out of ten patients showed a biochemical response after 16 months. A histological response was observed in 19/27 patients within a mean of 26.7 months. HBs seroconversion was found in 2/24 patients. Conclusion: Tenofovir is effective in the treatment of viral hepatitis B, but HBs seroconversion is rarely achieved.

关键词： Viral Hepatitis B Tenofovir Compliance Tolerance Efficacy

Upper Gastrointestinal Endoscopy at University Hospital Souro Sanou Bobo-Dioulasso (Burkina Faso), about 1022 Cases: Signs and Lesions Observed

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Open Journal of Gastroenterology 2017年第11期7卷 287-296页

作者： mali koura Delphine Passolguewindé Zongo Napon Zanga Damien Ouattara Kounpiélimé Sosthène Somda Aboubacar Coulibaly Steve Léonce Zoungrana Christine Couna Somé Bere Sandrine Hema Soudré Euloges Bébar Kamboulé Nogogna Zouré Honoré Zougmoré Inoussa Adama Zampou Appolinaire Sawadogo Gastroenterology Service of the University Hospital Souro Sanou Bobo-Dioulasso Burkina Faso Regional University Hospital of Ouahigouya Ouahigouya Burkina Faso Gastroenterology Service of the University Hospital Yalgado Ouédraogo Ouagadougou Burkina Faso Regional Hospital Kaya Kaya Burkina Faso National Hospital Blaise Compaoré Ouagadougou Burkina Faso

Upper gastrointestinal endoscopy is an excellent way for the diagnosis of high digestive pathology. We report the results of 1022 upper gastrointestinal endoscopy performed at Bobo-Dioulasso CHU-SS, in western Burkina Faso (West Africa). The aim of this study was to document the indications and lesions found in high endoscopy at the CHUSS. Patients and Methods: It was a cross-sectional study, prospective to describe the results of gastroscopy performed from 1st January 2015 to 30th June 2016 at the digestive endoscopy unit CHU-Souro Sanou Bobo-Dioulasso. Results: In the study period, 1022 upper gastrointestinal endoscopies were performed. The main indications were: The epigastric pain (48.6%), portal hypertension (10.7%) and gastroesophageal reflux disease (9.9%). The pathologies observed were dominated by gastropathies (48.11%), peptic ulcer (27%) and oesophageal varices (9.68%). Epigastralgias were the main circumstance for the discovery of: 52.3% of esophagitis, 49.17% of gastropathies and 46.12% of peptic ulcers. Histopathologically, the results of the 236 biopsies were dominated by gastritis (88.56%), stomach cancers (7.63%) and esophagus (3.81%). Conclusion: The main indication of the UGIE at the CHU-Souro Sanou in Bobo-Dioulasso was epigastralgia. The pathologies observed were dominated by gastropathy, esophagitis and PUD.

关键词： Upper Gastrointestinal Endoscopic Indications Lesions Observed Bobo-Dioulasso

EXISTENCE,MULTIPLICITY AND STABILITY RESULTS FOR POSITIVE SOLUTIONS OF NONLINEAR p-LAPLACIAN EQUATIONS

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Chinese Annals of Mathematics,Series B 2004年第2期25卷 275-286页

作者： mali SUNING DepartmentofMathematicalSciences TsinghuaUniversityBeijing100084China.

This paper studies the existence of positive solutions of the Dirichlet problem for the nonlinear equation involving p-Laplacian operator: -△pu = λf(u) on a bounded smooth domain Ω in Rn. The authors extend part of the Crandall-Rabinowitz bifurcation theory to this problem. Typical examples are checked in detail and multiplicity of the solutions are illustrated. Then the stability for the associated parabolic equation is considered and a Fujita-type result is presented.

关键词： p-Laplacian operator Bifurcation Multiplicity Positive solutions

Thermal Stability of Supercapacitor for Hybrid Energy Storage System in Lightweight Electric Vehicles:Simulation and Experiments

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Journal of Modern Power Systems and Clean Energy 2022年第1期10卷 170-178页

作者： Vima mali Brijesh Tripathi Department of Electrical Engineering/Solar Energy Pandit Deendayal Petroleum UniversityGandhinagarIndia Department of Science Pandit Deendayal Petroleum UniversityGandhinagarIndia

Recent research findings indicate that the non-monotonic consumption of energy from lithium-ion(Li-ion)batteries results in a higher heat generation in electrical energy storage *** peak demands,a higher heat generation due to high discharging current increases the temperature from 80℃ to 120℃,thereby resulting in thermal *** address peak demands,an additional electrical energy storage component,namely supercapacitor(SC),is being investigated by various research *** paper provides insights into the capability of SCs in lightweight electric vehicles(EVs)to address peak demands using the worldwide harmonized light-duty driving test cycle(WLTC)driving profile in MATLAB/Simulink at different ambient *** results indicate that temperature imposes a more prominent effect on Li-ion batteries compared with SCs under peak demand *** effect of the discharging rate limit on the Li-ion battery current is *** result shows that SCs can accommodate the peak demands for a low discharging current limit on the battery,thereby reducing heat *** impedance spectroscopy and cyclic voltammetry are performed on SCs to analyze their thermal performance at different temperatures ranging from 0℃ to 75℃ under different bias values of-0.6,0,0.6,and 1 V,*** results indicate a higher specific capacitance of the SC at an optimum operation temperature of 25℃ for the studied *** study shows that the hybrid combination of the Li-ion battery and SC for a lightweight EV can address peak demands by reducing thermal stress on the Li-ion battery and increasing the driving range.

关键词： Electric vehicle lithium-ion battery supercapacitor thermal stability

Event-Triggered Sampled-Data Consensus of Nonlinear Multi-Agent Systems with Control Input Losses

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Journal of Systems Science & Complexity 2018年第6期31卷 1469-1497页

作者： XING mali DENG Feiqi Department of Automation Science and Engineering South China University of Technology

This paper investigates the leader-following consensus problem for multi-agent systems with event-triggered mechanism and control packet *** on the local synchronization error, event-triggered mechanisms are proposed in order to reduce the number of controller *** control packet may lose due to unreliability of communication *** the assumption that once the packet loss happens the controller will be set to zero,sufficient consensus criteria for multi-agent system with event-triggered mechanism and control packet losses is *** is also shown that the interplay among the allowable packet loss rate,event-triggered mechanism and sampling *** illustrative example is given to demonstrate the effectiveness of the theoretical results.

关键词： Consensus control packet losses event-triggered mechanism multi-agent systems

Pancreatitis in pregnancy: etiology, diagnosis, treatment, and outcomes

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Hepatobiliary & Pancreatic Diseases International 2016年第4期15卷 434-438页

作者： Padmavathi mali Department of Internal Medicine Marshfield Clinic

BACKGROUND：Acute pancreatitis in pregnancy is a rare and dangerous *** study aimed to examine the etiology,treatment,and outcomes of pancreatitis in ***：A total of 25 pregnant patients diagnosed with pancreatitis during the period of 1994 and 2014 was analyzed ***：The pregnant patients were diagnosed with pancreatitis during a period of 21 ***（60%）of the patients were diagnosed with pancreatitis in the third *** mean age of the patients at presentation was 25.7 years,with a mean gestational age of 24.4 *** pain occurred in most patients and vomiting in one patient was associated hyperemesis *** common cause of the disease was gallstone-related（56%）,followed by alcohol-related（16%）,post-ERCP（4%）,hereditary（4%）and undetermined conditions（20%）.The level of triglycerides was minimally high in three *** and wire-guided sphincterotomy were performed in 6（43%）of 14 patients with gallstone-related pancreatitis and elevated liver enzymes with no ***（84%）of the patients underwent a full-term,vaginal *** was no difference in either maternal or fetal outcomes after ***：Acute pancreatitis is rare in pregnancy,occurring most commonly in the third trimester,and gallstones are the most common *** laparoscopic cholecystectomy is not feasible and a common bile duct stone is highly suspected on imaging,endoscopic sphincterotomy or stenting may help to prevent recurrence and postpone cholecystectomy until after delivery.

关键词： pancreatitis alcoholic pancreatitis pregnancy complications diagnostic imaging

Photocatalytic activity of metal nanoparticle-decorated titanium dioxide for simultaneous H_(2) production and biodiesel wastewater remediation

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Chinese Journal of Chemical Engineering 2021年第8期34卷 86-100页

作者： Patsakol Prayoonpunratn Trin Jedsukontorn mali Hunsom Fuels Research Center Department of Chemical TechnologyFaculty of ScienceChulalongkorn UniversityBangkok 10330Thailand Current address:Department of Chemical Engineering Faculty of EngineeringMahidol UniversityNakorn Pathom 73170Thailand Associate Fellow of Royal Society of Thailand(AFRST) Bangkok 10300Thailand

A set of metal nanoparticle-decorated titanium dioxide(Mx/TiO_(2);where x is the percent by mass,%)photocatalysts was prepared via the sol-immobilization in order to enhance the simultaneous hydrogen(H_(2))production and pollutant reduction from real biodiesel *** of the metal nanoparticle(NP)type(M=Ni,Au,Pt or Pd)and,for Pd,the amount(1%–4%)decorated on the surface of thermal treated commercial TiO_(2)(T_(400))was *** obtained results demonstrated that both the type and amount of decorated metal NPs did not significantly affect the pollutant reduction,measured in terms of the reduction of chemical oxygen demand(COD),biological oxygen demand(BOD)and oil&grease levels,but they affected the H_(2) production rate from both deionized water and biodiesel wastewater,which can be ranked in the order of Pt_(1)/T_(400)>Pd_(1)/T_(400)>Au_(1)/T_(400)>Ni_(1)/T_(400).This was attributed to the high difference in work function between Pt and the parent ***,the difference between Pt1/T400 and Pd1/T400 was not great and so from an economic consideration,Pd/TiO_(2) was selected as appropriate for further *** the four different Pdx/TiO_(2) photocatalysts,the Pd3/TiO_(2) demonstrated the highest activity and gave a high rate of H_(2) production(up to 135 mmol·h−1)with a COD,BOD and oil&grease reduction of 30.3%,73.7%and 58.0%,respectively.

关键词： Hydrogen production Wastewater Remediation Photochemistry Metal nanoparticle-decorated titanium dioxide