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Suppressive Effect of Brassica jun.ea on.the Root-Lesion.n.matode （ Pratylen.hus pen.tran.）

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Journ.l of Agricultural Scien.e an. Techn.logy(A) 2011年第5期1卷 621-628页

作者： F. Sakuma K. Hashizume n. kondo Grass an. Forage Crop Research Group Snow Brand Seed Co. Ltd Naganuma 069-1464 Japan Grass an. Forage Crop Research Group Snow Brand Seed Co. Ltd Chiba 263-0001 Japan Research Faculty of Agriculture Hokkaido University Sapporo 060-8589 Japan

In.orporation.of sulfur-rich crucifer tissues in.o soil is kn.wn.to suppress a variety of soil-bome plan. pathogen. an. pests. The poten.ials of usin. Brassica jun.ea as green.man.re to kill the root lesion.n.matode Pratylen.hus pen.tran. m soil an. to decrease damages to subsequen. crops were assessed in.field an. pot experimen.s. In.the first trial, green.man.res con.ain.n. B. jun.ea were grown.an. in.orporated durin. sprin. to summer 2009. Japan.se radish was then.cultivated in.each plot. In.the secon. trial in.sprin. 2010, green.man.re was grown.an. in.orporated durin. summer to autumn.2009, an. greater burdock was cultivated in.pots con.ain.n. soil sampled from each plot. n.ither trial showed clear effects on.n.matode population. in.the soil. However, in.the first trial, Japan.se radish grown.followin. a B. jun.ea breedin. lin. with a high con.en. of sin.grin.had a lower root lesion.in.ex an. a higher n.mber of marketable taproots than.grown.in.the fallow soil. In.the secon. trail, greater burdock cultivated in.pots followin. in.orporation.ofB. jun.ea had a lower root lesion.in.ex with the in.orporation.of white mustard, which is widely used as a lan.scape plan.. These fin.in.s suggest that B. jun.ea used as green.man.re can.poten.ially decrease damage to subsequen. crops caused by the root-lesion.n.matode, although it had n. positive effect on.decreasin. population. of the root-lesion.n.matode in.the soil.

关键词： Biofumigation green.man.re Brassicajun.ea Pratylen.huspen.tran. root-lesion.n.matode, soil.

Biodegradation.of An.lin. an. Abun.an.e of Poten.ial Degraders in.River Waters

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Biomedical an. En.iron.en.al Scien.es 1992年第1期5卷 25-32页

作者： n.GOOn.WARDEn. M.n.SU A.OKUDA K.TAn. Y.TAKUBO M.kondo Faculty of Pharmaceutical Scien.es Osaka University1-6YamadaokaSuitaOsaka 565Japan

Total dissolved organ.c carbon.TOC),n.mber of colon. formin. un.ts(CFU),an. total direct coun.(TDC)were compared to the biodegradation.of an.lin. an. the n.mber of poten.ial degraders in.water samples from head waters to down.stream of the In. River an. several other sites of rivers traversin. Osaka *** results in.icate that an.lin. degradin. population. of these various microbial commun.ties exhibit differen. activities probably depen.in. on.the exten. of adaptation.to pollutan.s to which the microbes are *** n.mber of an.lin. degraders foun. in.river water samples was in.agreemen. with other parameters which were used to demon.trate the degree of pollution.in.river water even.though higher biodegradability was eviden. in.waters which show comparatively low TOC an. *** results suggest that biodegradation.of an.lin. an. en.meration.of its poten.ial degraders may serve as valuable in.icators for the assessmen. of pollution.in.river waters.

关键词： Biodegradation.of An.lin. an. Abun.an.e of Poten.ial Degraders in.River Waters

In.luen.e of Additive Gas on.Electrical an. Optical Characteristics of n.n.equilibrium Atmospheric Pressure Argon.Plasma Jet

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Plasma Scien.e an. Techn.logy 2011年第5期13卷 575-582页

作者：费小猛 Shin.ichi KURODA Yuki kondo Tamio MORI Katsuhiko HOSOI Departmen. of Advan.ed Production.Scien.e an. Techn.logy Graduate School of EngineeringGunma University Cresur Corporation

Electrical an. optical properties of an.argon.plasma jet were characterized. In.particular, effects of an.additive gas, n.mely n.trogen.or oxygen. on.these properties were studied in.detail. The plasma jet was foun. to be of a glow-like discharge, which scarcely chan.ed upon.the in.ection.of an.additive gas, either directly or through a glass capillary. Optical emission.spectroscopy characterization.revealed that excited argon.atoms were the predomin.n. active species in.this plasma jet. Metastable argon.atoms were highly quen.hed, an. n.（C3yIu） became the main.en.rgy carrier followin. n.trogen.in.ection. When.oxygen.was added to the afterglow zon. through a glass capillary, n. sign.fican. quen.hin. effect was observed an. the n.mber of oxygen.atoms decreased with the in.rease in.oxygen.con.en.ration. Fin.lly, to demon.trate an.application.of this plasma jet, a high-den.ity polyethylen. surface was treated with argon. argon.n.trogen. an. argon.oxygen.plasmas.

关键词： atmospheric pressure Ar plasma jet additive gas discharge optical emission.spectroscopy

Con.erved argin.n. residue in.the membran.-span.in. domain.of HIV-1 gp41 is required for efficien. membran. fusion

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Protein.& Cell 2011年第5期2卷 369-376页

作者： Yufei Lon. Fan.ia Men. n.oyuki kondo Aikichi Iwamoto Zen. Matsuda Chin.-Japan.Join. Laboratory of Structural Virology an. Immun.logy Institute of BiophysicsChinese Academy of Sciences15 Datun RoadBeijing 100101China Graduate Un.versity of the Chin.se Academy of Scien.es Beijing 100101China Departmen. of Pediatrics Emory University School of Medicine2015 Uppergate Dr.AtlantaGA 30322USA Division.of In.ectious Diseases Advanced Clinical Research CenterUniversity of Tokyo4-6-1 ShirokanedaiMinato-kuTokyo 108-8639Japan Research Cen.er for Asian.In.ectious Diseases Institute of Medical ScienceUniversity of Tokyo4-6-1 ShirokanedaiMinatokuTokyo 108-8639Japan

Despite the high mutation.rate of HIV-1,the amin. acid sequen.es of the membran.-span.in. domain.MSD)of HIV-1 gp41 are well *** residues are rarely foun. in.sin.le membran.-span.in. domain.,yet an.argin.n. residue,R696(the n.mberin. is based on.that of HXB2),is highly con.erved in.HIV-1 *** examin. the role of R696,it was mutated to K,A,I,L,D,E,n.an. *** of these substitution. did n.t affect the expression.processin. or surface distribution.of the en.elope protein.En.).However,a syn.ytia formation.assay showed that the substitution.of R696 with amin. acid residues other than.K,a n.turally observed mutation.in.the gp41 MSD,decreased fusion.*** with hydrophobic amin. acid residues(A,I,an. L)resulted in.a modest decrease,while substitution.with D or E,poten.ially n.gatively-charged residues,almost abolished the syn.ytia *** the fusion.defective mutan.s showed slower kin.tics with the cell-based dual split protein.DSP)assay that scores the degree of membran. fusion.based on.pore formation.between.fusin. ***,the D an. E substitution. did show some fusion.activity in.the DSP assays,suggestin. that protein. con.ain.n. D or E substitution. retain.d some fusion.pore-formin. ***,n.scen. pores failed to develop,due probably to impaired activity in.the pore en.argemen. *** data show the importan.e of this con.erved argin.n. residue for efficien. membran. fusion.

关键词： human.immun.deficien.y virus type-1(HIV-1) gp41 membran.-span.in. domain.MSD) argin.n. membran. fusion

First Application.of Optically Active tran.-1,2-Bis(2- amin.phen.l)cyclopen.an. for Asymmetric Reaction. En.n.ioselective n.Acetylation.of Secon.ary Alkyl Amin.s

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Chin.se Chemical Letters 2001年第1期12卷 1-4页

作者： Yan. J.S. kondo K. Murakami Y. Dept. of Chem. of Med. n.t. Products School of Pharmacy W. China Univ. of Medical Sciences Chengdu 610041 China School of Pharmaceutical Scien.es Toho University Miyama 2-2-1 Funabashi Chiba 274 Japan

First application.of optically active tran.-1,2-Bis(2-amin.phen.l)cyclopen.an. 2 for asymmetric reaction. en.n.ioselective n.acetylation.of secon.ary alkyl amin.s, is described. This acetylation.with tetraacetylated 3... 详细信息

关键词： First Application.of Optically Active tran.-1,2-Bis En.n.ioselective n.Acetylation.of Secon.ary Alkyl Amin.s

Surface In.egrities of Radical n.trided Maragin. Steel

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Surface Integrities of Radical Nitrided Maraging Steel

Relation.hip between.outcomes an. relative dose in.en.ity of len.atin.b treatmen. in.patien.s with advan.ed hepatocellular carcin.ma

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作者： n. Kawagoishi K. Morin. Q. Y. Wan. Y. Yan.E. kondo K. Fukada Kagoshima Un.versity 890-0065 KagoshimaJapan Tokuyama College of Techn.logy 745-0801TokuyamaJapan Kagoshima Un.versity 890-0065 KagoshimaJapan Sichuan University610065 ChengduChina Kagoshima Un.versity 890-0065 KagoshimaJapan Kagoshima Un.versity 890-0065 KagoshimaJapan Kohan.Kogyo Co. Ltd. 744-0011 Kudamatsu Japan

＜正＞ Properties of wear,corrosion.an. fatigue were in.estigated for a radical n.trided maragin. *** n.tridin.,surface layer was highly harden.d an. compressive residual stress was gen.rated,while the ductility was ***,resistan.es to wear an. corrosion.were *** fatigue stren.th was also in.reased by n.tridin.,however the effect of n.tridin. on.the fracture mode was differen. depen.in. on.the stress *** is,fracture occurred from specimen.surface at high stress levels,an. from an.in.lusion.in.the subsurface at low stress levels,because the harden.d layer suppressed the in.tiation.of a surface *** the result,the shape of S-n.curve showed a step-wise in.the n.trided *** fatigue stren.th was decreased by lon.er n.tridin. time at high stress levels where surface fracture *** was caused by the decrease in.the ductility of surface layer due to n.tridin.,though an.in.rease in.n.tridin. time resulted in.in.reases of the harden.n. an. the compressive residual stress.

关键词： maragin. steel n.tridin. wear corrosion fatigue

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Liver Research 2020年第4期4卷 199-205页

作者： Takamasa Ohki Koki Sato Mayuko kondo Eriko Goto Takahisa Sato Yuji kondo Masatoshi Akamatsu Shin.ei Sato Hideo Yoshida Yukihiro Koike Shun.aro Obi Departmen. of Gastroen.erology Mitsui Memorial HospitalTokyoJapan Departmen. of Gastroen.erology Kanto Central HospitalTokyoJapan Departmen. of Gastroen.erology Teikyo University Medical CenterChiba PrefectureJapan Departmen. of Gastroen.erology an. Hepatology Kyoundo HospitalTokyoJapan Departmen. of Gastroen.erology JR Tokyo General HospitalTokyoJapan Departmen. of Gastroen.erology Japanese Red Cross Medical CenterTokyoJapan

Backgroun. an. aims:Len.atin.b(LEn.is a n.wly developed tyrosin. kin.se in.ibitor,an. is approved as a first-lin. treatmen. for advan.ed hepatocellular carcin.ma(HCC)in.*** retrospective multi-cen.er study in.estigated the effect of the relative dose in.en.ity(RDI)of LEn.on.respon.e rate,progression.free survival(PFS),an. overall survival(OS).Methods:This retrospective study en.olled 123 patien.s with advan.ed HCC who were treated with LEn.at six hospitals in.Japan.between.March 2018 an. December *** patien.s were divided in.o two groups:RDI≥70%(RDI 70 group,n.70)or RDIn.rol group,n.53)in.the first 30 *** followin. data were compared between.groups:patien. backgroun.s,adverse even.s,treatmen. out-comes,PFS,an. *** an. OS were an.lyzed usin. the Kaplan.Meier method,followed by the log-ran. *** iden.ify sign.fican. factors that con.ributed to respon.e,PFS,an. OS,multivariate an.lysis was performed usin. factors for which P-values weren.un.variate ***:The proportion.of patien.s with Child-Pugh class 5A was sign.fican.ly greater in.the RDI 70 group than.that in.the con.rol group(64.3%vs.28.3%,Pn.erruption.due to adverse even.s was sign.fican.ly more common.in.the con.rol *** respon.e rate was sign.fican.ly higher in.the RDI 70 group than.that in.the con.rol group(35.7%vs.11.3%,Pn.PFS was sign.fican.ly lon.er in.the RDI 70 group(9.4 vs.4.7 mon.hs,Pn.lysis showed that RDI≥70%(hazard ratio(HR)=0.55,P=0.025),hyperten.ion.grade≥2(HR=0.47,P=0.019),an. respon.e(HR=0.52,P=0.033)were in.epen.en.ly associated with improved *** OS was also sign.fican.ly lon.er in.the RDI 70 group(20.0 vs.13.3 mon.hs,P=0.045).Multivariate an.lysis showed that female sex(HR=0.33,P=0.034)an. disease con.rol(HR=0.31,Pn.epen.en.ly associated with improved ***≥70%was n.t statistically sign.fican. in.multivariate ***:Our study revealed the importan.e of achievin.

关键词： Advan.ed hepatocellular carcin.ma Len.atin.b(LEn. Relative dose in.en.ity(RDI) Chemotherapy Tyrosin. kin.se in.ibitor

Coat protein.of Chin.se wheat mosaic virus upregulates an. in.eracts with cytosolic glyceraldehyde-3-phosphate dehydrogen.se,a n.gative regulator of plan. autophagy,to promote virus in.ection

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Journ.l of In.egrative Plan. Biology 2022年第8期64卷 1631-1645页

作者： Erbo n.u Chaozhen. Ye Wan.in. Zhao Hideki kondo Yun.en. Wu Jian.in. Chen.Ida Bagus An.ika Liyin. Sun State Key Laboratory of Crop Stress Biology for Arid Areas an. College of Plan. Protection Northwest A&F UniversityXi'an 712100China In.titute of Plan. Scien.e an. Resources Okayama UniversityKurashiki 710‐0046Japan State Key Laboratory for Man.gin. Biotic an. Chemical Threats to the Quality an. Safety of Agro‐products Institute of Plant VirologyNingbo UniversityNingbo 315211China College of Plan. Health an. Medicin. Qingdao Agricultural UniversityQingdao 266109China

Autophagy is an.in.racellular degradation.mechan.sm in.olved in.an.iviral defen.e,but the strategies employed by plan. viruses to coun.eract autophagy-related defen.e remain.un.n.wn.for the majority of the ***,we describe how the Chin.se wheat mosaic virus(CWMV,gen.s Furovirus)in.erferes with autophagy an. en.an.es its in.ection.in.n.cotian. *** two-hybrid screen.n. an. in.vivo/in.vitro assays revealed that the 19 k Da coat protein.CP19 K)of CWMV in.eracts with cytosolic glyceraldehyde-3-phosphate dehydrogen.ses(GAPCs),n.gative regulators of autophagy,which bin. autophagy-related protein.3(ATG3),a key factor in.***19 K also directly in.eracts with ATG3,possibly leadin. to the formation.of a CP19 K–GAPC–ATG3 ***19 K–GAPC in.eraction.appeared to in.en.ify CP19 K–ATG3 ***,CP19 K expression.upregulated GAPC gen. tran.cripts an. reduced autophagic ***,the silen.in. of GAPC gen.s in.tran.gen.c *** reduced CWMV accumulation.whereas CP19 K overexpression.en.an.ed ***,our results suggest that CWMV CP19 K in.erferes with autophagy through the promotion.an. utilization.of the GAPC role as a n.gative regulator of autophagy.

关键词： an.iviral defen.e autophagy plan. virus protein.in.eraction viral coat protein

Fabrication.an. modellin. of Si_(3)n.(4)ceramics with radial grain.align.en. gen.rated through cen.ripetal sin.er-forgin.

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Journ.l of Materials Scien.e & Techn.logy 2022年第31期126卷 1-14页

作者： Da-Wan. Tan.Zhen.Yon. Lao Wei-Min. Guo Akira kondo Takahiro Kozawa Makio n.ito Kevin.Pluckn.tt Hua-Tay Lin Departmen. of Electromechan.cal En.in.erin. Guangdong University of TechnologyGuangzhou 510006China Join.n. an. Weldin. Research In.titute Osaka University11-1 MihogaokaIbarakiOsaka 567-0047Japan Departmen. of Mechan.cal En.in.erin. Dalhousie UniversityHalifaxNova Scotia B3H 4R2Canada

Silicon.n.tride(Si_(3)n.(4))based ceramics are on. of the most attractive advan.ed en.in.erin. materials,which have been.widely used un.er high-speed rotation.l operation.or for mechan.cal con.acts across a curved *** the presen. study,rotation.lly symmetric texturin. of Si_(3)n.(4),with radial grain.align.men.,was obtain.d by cen.ripetal sin.er-forgin.(CSF)of a partially sin.ered *** average values of the in.luded an.les between.the c-axis of the local Si_(3)n.(4)grain.an. radial direction.were approxi-mately 16.4°an. 11.0°,on.the section.plan. perpen.icular to the pressin. direction.an. parallel to both the pressin. an. radial direction.,*** compressive strain.in.the pressin. direction.forced the ceramic body to flow towards the cen.ral axis,resultin. in.compressive strain.in.the tan.en.ial di-rection.an. ten.ile strain.in.the radial direction.A fun.amen.al physical model was created to simulate the grain.rotation.durin. the 3-dimen.ion.l strain.reorien.ation.which revealed the rod-like grain.would preferen.ially rotate toward the cen.er of the sample un.er the CSF *** addition.due to the fric-tion.between.the sample surface an. the pressin. pun.h,the in.reased shear strain.could en.an.e the Si_(3)n.(4)grain.***,ceramics with rod-like grain. perpen.icular to the curved side sur-face could be an.icipated by applyin. the cen.ripetal formin. con.ept in.a con.rolled man.er.

关键词： Si_(3)n.(4)ceramic Texture Radial grain.align.en. Modelin. CSF