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Journal of Environmental Sciences 2024年第7期141卷 314-329页

作者： komal Daya Soni Khem singh Shankar G.Aggarwal CSIR-National Physical Laboratory Dr.K.S.Krishnan MargNew Delhi 110012India Academy of Scientific&Innovative Research(AcSIR) Ghaziabad 201002India

Vehicular emissions are considered one of the major anthropogenic sources of greenhouse gases and poor air quality in metropolitan *** study aims to see the correlation of CO_(2),CH_(4),and CO through monitoring over a period from December 2020 to October 2021 covering three seasons’winter,summer,and monsoon at two different traffic locations of Delhi having different traffic volumes,road patterns,and traffic *** annual average morning concentration of CO_(2),CH_(4)and CO was found(533±105),(7.3±3.1),(10.7±3.0)ppm at Najafgarh and(480±70),(5.2±1.8),(7.8±2.8)ppm at Rajendra Place,respectively.A relationship between concentration of all three gases and meteorological parameters such as temperature,humidity,wind speed and wind direction has also been investigated using Pearson correlation coefficient and pollution rose diagram.A comparable pattern in concentration was observed for all three gases in spatial(location)and temporal(diurnal)*** concentration trend of CO_(2)in different seasons is winter>summer>monsoon,while in the case of CH_(4)winter=summer>monsoon but not any seasonal trend was noted in CO *** is observed that CO_(2)has a good relation with CO(a tracer for vehicular emission)in terms of diurnal variation,whereas,CH_(4)does not represent a relation with CO and CO_(2)diurnally,suggesting that vehicles are the source of CO_(2)but not much contributing to other greenhouse gases like CH_(4).

关键词： Vehicular emission Greenhouse gases Harmful pollutants Meteorological parameters

Nimotuzumab with Concurrent Chemoradiation in Inoperable Locally Advanced Squamous Cell Carcinoma of Head and Neck: An Indian Experience

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Journal of Cancer Therapy 2018年第1期9卷 89-100页

作者： Ankur Bahl komal singh Pragati Choudhary A. K. Anand Amal Roy Chaoudhoory Harit Chaturvedi Biswajyoti Hazarika Dilip Pawar Medical Oncology Max Super Specialty Hospital Saket New Delhi India Radiation Oncology Max Super Specialty Hospital Saket New Delhi India Surgical Oncology Max Super Specialty Hospital Saket New Delhi India Medical Affairs & Clinical Development Biocon Banglore India

Background: The prognosis of patients with Epidermal Growth Factor Receptor (EGFR) overexpression in inoperable Locally Advanced Squamous Cell Carcinoma of Head and Neck (LASCCHN) remains poor. Nimotuzumab is an Anti EGFR humanized monoclonal antibody approved for treatment of LASCCHN, with concurrent chemoradiation. Objective: To assess the efficacy and safety of nimotuzumab with concurrent chemoradiation in inoperable LASCCHN patients. Methodology: This is a single-centre, single arm, retrospective study evaluating 35 patients with histologically confirmed inoperable LASCCHN (stages III-IV). The patients were administered IV cisplatin 50 mg/m2 and IV nimotuzumab 200 mg for 6 - 7 weeks, along with radiotherapy of 6600 - 7000 cGy over 35 fractions. Patients were evaluated over response evaluation criteria in solid tumors (RECIST) criteria 12 weeks after the last cycle of chemotherapy. They were also followed up for overall survival and relapse free survival. Results: The median duration of follow-up was 20 months. The most common site of cancer was oropharynx (68.6%). One patient was lost to follow up. Objective Response Rate (ORR) was observed in 97% of the patients with 17 patients (48.6%) achieving complete response (CR) and 17 patients (48.6%) achieving partial response (PR). The median overall survival was 22.7 months (95% CI: 21.30, 34.27). The median relapse free survival was 16.7 months (95% CI: 9.80, 24.50). Nimotuzumab was safe and well tolerated with few mild, self-limiting adverse events. Conclusion: Nimotuzumab with chemoradiation is a safe and efficacious option in patients with LASCCHN. Larger studies are needed to verify the same.

关键词： Epidermal Growth Factor Receptor Chemoradiation Locally Advanced Squamous Cell Carcinoma of Head and Neck Humanised Monoclonal Antibody Nimotuzumab

Semantic segmentation of landcover for cropland mapping and area estimation using Machine Learning techniques

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Data Intelligence 2023年第2期5卷 370-387页

作者： Surabhi Lingwal komal Kumar Bhatia Manjeet singh Computer Science&Engineering G B Pant Institute of Engineering&TechnologyPauri Garhwal246194UttarakhandIndia Computer Engineering J C Bose Univerity of Science&TechnologyYMCAFaridabad121006HaryanaIndia

The paper has focussed on the global landcover for the identification of cropland *** growth and rapid industrialization are somehow disturbing the agricultural lands and eventually the food production needed for human *** agricultural land monitoring requires proper management of land *** paper has proposed a method for cropland mapping by semantic segmentation of landcover to identify the cropland boundaries and estimate the cropland areas using machine learning *** process has initially applied various filters to identify the features responsible for detecting the land boundaries through the edge detection *** images are masked or annotated to produce the ground truth for the label identification of croplands,rivers,buildings,and *** selected features are transferred to a machine learning model for the semantic segmentation *** methodology has applied Random Forest,which has compared to two other techniques,Support Vector Machine and Multilayer perceptron,for the semantic segmentation *** dataset is composed of satellite images collected from the QGIS *** paper has derived the conclusion that Random forest has given the best result for segmenting the image into different regions with 99%training accuracy and 90%test *** results are cross-validated by computing the Mean loU and kappa coefficient that shows 93%and 69%score value respectively for Random Forest,found maximum among *** paper has also calculated the area covered under the different segmented ***,Random Forest has produced promising results for semantic segmentation of landcover for cropland mapping.

关键词： Croplands Semantic Segmentation Machine Learning Random Forest Mask filters Edge detection Supportvectormachine

Monitoring and modeling of urban sprawl through remote sensing and GIS in Kuala Lumpur, Malaysia

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Ecological Processes 2015年第1期4卷 165-174页

作者： Mukesh singh Boori Maik Netzband komal Choudhary Vít Voženílek Palacky University Olomouc 17.listopadu 5077146 OlomoucCzech Republic Geographical Institute Ruhr University BochumBochumGermany Samara State Aerospace University SamaraRussia

Introduction:Kuala Lumpur is currently experiencing a large-scale urban *** study explores a multi-buffer ring method to investigate the spatial and temporal dynamics of urban growth in the Kuala Lumpur metropolitan area by using Geographical Information Systems(GIS)and remote sensing imageries from1989 to ***:The first Landsat images from 1989,2001,and 2014 were classified with maximum likelihood classification to produce land cover maps and identify four types of land cover:urban/built-up,agriculture,forest,and ***,the area coverage for all the land use types at different points in time were measured and combined with distance from the city *** on,urbanization densities from the city center to the outside for every 1-km distance from 1 to 50 km are ***:City density on the distance of 5,8,15,20,and 30 km was very high in the years 1989 and ***,urban expansion shows fast and slow growth stages with high-speed growth shifting to the east side of the ***:In general,the population,traffic conditions,industrialization,and policy are the major factors thatinfluenced the urban expansion.

关键词： Urbanization Landsat Change detection Remote Sensing GIS

Catalytic Cracking of Waste Polypropylene in a Nitrogen Fluidized Bed Reactor

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Journal of Geoscience and Environment Protection 2016年第4期4卷 20-25页

作者： Anil Vyas Suresh Kumar singh komal Sharma Sukhwant singh Chemical Engineering Department Jai Narain Vyas University Jodhpur India Civil Engineering Department Jai Narain Vyas University Jodhpur India Chemical Engineering Department MNIT Jaipur India

Polypropylene (PP) is rated first as volume leader in the plastic sector. Its non-biodegradable property poses serious environmental problem in case of disposal. The catalytic cracking of PP was performed with various catalysts i.e. ZSM-5, Zeolite, RB and SPS. The cracking was observed under different feed to catalyst ratio i.e. 1:1 to 5:1. The fluidized bed reactor was fabricated with arrangement to measure the temperature ranging from 100。C to 800。C. The effective of feed to catalyst ratio was found 3:1 at a temperature range of 420。C - 510。C and catalyst ZSM-5 gives maximum liquid conversion of waste PP. Conversion of PP to liquid fuel will not only resolve the problem of disposal of waste polypropylene plastic but also give a value aided product.

关键词： Waste PP Pyrolysis Catalytic Cracking ZSM-5 Zeolite Liquid Fuel

Neutralizing possibilities of whole virion and mRNA vaccine triggered antibodies of Wuhan strain of SARS-CoV-2 with receptor binding domains of spike proteins of Delta and Omicron strains

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Asian Pacific Journal of Tropical Medicine 2023年第2期16卷 92-94,I0008页

作者： Shilpa Barthwal Bennet Angel Annette Angel Vinod Joshi BM Shareef Nuzhat M Peer Poorna Khaneja Ambreen S Khan Bhawna Sharma Neha singh Ramesh Joshi komal Tomar Kiran Yadav Satendra P singh Advance Centre for Virology&Immunology Sharda UniversityGreater NoidaU.P.201310India Sharda School of Agricultural Sciences Sharda UniversityGreater NoidaU.P.201310India Department of Microbiology School of Medical Sciences&ResearchSharda HospitalGreater NoidaU.P.201310India

Mutations in the receptor binding domain(RBD)of SARS-CoV-2 spike protein have given birth to the new variants of concern *** and Omicron *** we are using vaccines which are either mRNA of spike protein of Wuhan strain or its whole virion vaccine,these vaccines will trigger antibodies to be able to bind with the epitopes of spike protein of Wuhan *** appears a need to study whether vaccine generated circulating neutralizing antibodies in vaccinated people are able to neutralize the receptor binding domain of spike protein of currently circulating Delta and Omicron strains as *** need to address this contention in two phases:first to undertake docking studies of vaccine generated antibodies with Wuhan,Delta and Omicron strains and second to conduct the wet lab studies and observe antigen-antibody bindings employing Immunofluorescence and Cryo-Electron Microscopic *** present paper reports results of docking studies using bioinformatic softwares to provide the baseline information for wet lab studies.

关键词： vaccine antibodies neutral