检索结果-南通市图书馆

The dual role of necrostatin-1 in Parkinson’s disease models

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第10期16卷 2019-2020页

作者： Eva Alegre-Cortes Guadalupe martinez-Chacon Jose m.Fuentes Sokhna m.S.Yakhine-Diop Universidad de Extremadura Depto.Bioquimica y Biologia Molecular y GeneticaFacultad de Enfermeria y Terapia OcupacionalAvda de la Universidad s/nCaceresSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED)madrid Spain Instituto Universitario de Investigacion Biosanitaria de Extremadura(INUBE) CaceresSpain

Neuronal cell death is the main hallmark of Parkinson’s disease(PD).It is an irreversible process promoted by neurotoxins and/or genetic *** types of cell death have been associated with *** mechanisms by which neurons decide to specific type of cell death remain ***,it is well known that cell death can be either programmed or *** is a programmed cell death that involves the release of cytochrome c from damaged mitochondria to cytosol and the activation of caspases leading to nuclear *** is a caspase-independent cell death characterized by a gain in cell volume,rupture of plasma membrane and leak of cell contents,inflammation,and affects neighbouring *** was classified as a nonprogrammed cell death,but there are types of necrotic death triggered by a protein activation cascade,including necroptosis.

关键词： inflammation Necrosis rupture

Superhydrophobic surface of mg alloys:A review

在线全文

学校读者我要写书评

暂无评论

Journal of magnesium and Alloys 2018年第1期6卷 59-70页

作者： m.Yeganeh N.mohammadi Department of materials Science and Engineering Faculty of EngineeringShahid Chamran University of AhvazAhvazIran

In the present review,the formation of superhydrophobic(SHP)structures on the surface of mg alloys was *** methods including hydrothermal technique,chemical and electrochemical deposition,conversion and polymer coating,and etching routes were *** superhydrophobicity could form on the surface of mg alloys by the application of different chemical,electrochemical,and physical methods followed by the immersion of these alloys in the solution containing modifying agents including fatty acids or long-chain *** formed morphology,composition,and contact angle were reported and the effect of synthesis route on these characteristics was reviewed.

关键词： mg alloys Superhydrophobic surfaces Chemical deposition Electrochemical coating Conversion coating Polymer coating Etching

Interplay between strong Allee effect, harvesting and hydra effect of a single population discrete-time system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Biomathematics 2016年第1期9卷 65-89页

作者： Debaldev Jana Elsayed m. Elsayed Ecological modelling LaboratoryDepartment of Zoology Visva-Bharati University Santiniketan 731235 India mathematics DepartmentFaculty of Science King Abdulaziz UniversityP. O. Box 80203 Jeddah 21589 Saudi Arabia Department of mathematicsFaculty of Science Mansoura University Mansoura 35516 Egypt

The dynamics of a single population with non-overlapping generations can be described deterministically by a scalar difference equation in this study. A discrete-time Beverton- Holt stock recruitment model with Allee effect, harvesting and hydra effect is proposed and studied. model with strong Allee effect results from incorporating mate limitation in the Beverton-Holt model. We show that these simple models exhibit some interesting （and sometimes unexpected） phenomena such as the hydra effect, sudden collapses and essential extinction. Along with this, harvesting is a socio-economie issue to continue any system generation after generation. Different dynamical behaviors for these situations have been illustrated numerically also. The biological implications of our analytical and numerical findings are discussed critically.

关键词： Beverton-Holt model hydra effect harvesting Allee effect.

Stability analysis of slopes with planar failure using variational calculus and numerical methods

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2020年第5期14卷 1262-1273页

作者： Norly BELANDRIA RobertoÚCAR Francisco m.LEON Ferri HASSANI Geological Engineering School University of Los AndesMérida 5101Venezuela mechanical Engineering School University of Los AndesMérida 5101Venezuela Department of mining and material Engineering McGill UniversityMontrealQC H3A 0E9Canada

This study investigates the technique of variational calculus applied to estimate the slope stability considering the mechanism of planar *** critical plane failure surface should be determined because it theoretically indicates the most unfavorable plane to be considered when stabilizing a slope to rectify the instability generated by several statistically possible *** generates integrals that can be solved by numerical methods,such as the Newton Cotes and the finite differences ***,a system of nonlinear equations is obtained and *** surface of the critical planar failure is determined by applying the condition of transversality in mobile boundaries,for which various examples are *** number of slices is varied in one of the examples,while the surface of the critical planar failure is determined in the *** are compared using analytical methods through axis *** the results obtained by considering normal stress,safety factors,and critical planar failure are nearly the same;however,in this research,a study is carried out for“n”number of slices using programming ***-routines are important because they can be applied in slopes with different geometry,surcharge,interstitial pressure,and pseudo-static load.

关键词： slopes stability planar failure variational calculus numerical methods

A compliant polymorphing wing for small UAVs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2020年第10期33卷 2575-2588页

作者： Sadique P.mUHAmmED Rafic m.AJAJ Kamran AKHAN Department of mechanical Engineering United Arab Emirates UniversityAl Ain 15551United Arab Emirates Department of Aerospace Engineering Khalifa University of Science and TechnologyAbu Dhabi 127788United Arab Emirates

This paper presents the development of a novel compliant polymorphing wing capable of chord and camber morphing for small *** morphing wing can achieve up to 10%chord extension and±20°camber *** design,modeling,sizing,manufacturing and mechanical testing of the wing are *** polymorphing wing consists of one continuous front spar fixed to the fuselage and a rear spar on each side of the *** rear spar can translate in the chordwise direction(chord morphing)and rotate around itself(camber morphing).A flexible elastomeric latex sheet is used as the skin to cover the wing and maintain its aerodynamic shape whilst allowing *** loads from the skin are transferred to the spars using the compliant cellular ribs that support the flexible skin and facilitate ***-tensioning is applied to the skin to minimize wrinkling when subject to aerodynamic and actuation loads.A rack and pinion actuation system,powered by stepper motors,is used for ***-structural design,analysis and sizing are *** comparison between the polymorphing wing and the baseline wing(non-morphing)shows that chord morphing improves aerodynamic efficiency at low angles of attack while camber morphing improves efficiency at high angles of attack.

关键词： Camber morphing Chord morphing Compliant structures Flexible skin UAVs

Characterization and mode of action analysis of black soldier fly(Hermetia illucens)larva-derived hemocytes

在线全文

学校读者我要写书评

暂无评论

Insect Science 2022年第4期29卷 1071-1095页

作者： Yvette m.von Bredow Ariane müller Philipp F.Popp Denis Iliasov Christoph-Rüdiger von Bredow Justus-Liebig-Universität Gießen Institut für Allgemeine Zoologie und EntwicklungsbiologieZelluläre Erkennungs-und AbwehrprozesseGießenGermany Technische Universität Dresden Fakultät BiologieInstitut für ZoologieDresdenGermany Technische Universität Dresden Fakultät BiologieInstitut für MikrobiologieDresdenGermany Present address:Philipp F.Popp Institute for Biology-Bacterial PhysiologyHumboldt-Universität zu BerlinBerlinGermany

With the growing importance of the black soldier fly(Hermetia illucens)for both sustainable food production and waste management as well as for science,a great demand of understanding its immune system ***,we present the first description of the circulating larval hemocytes with special emphasis on uptake of microorganisms and distinguishing hemocyte *** histological,zymographic,and cytometric methods and with a set of hemocyte binding lectins and antibodies,the hemocytes of *** are identified as plasmatocytes,crystal cells,and putative *** hemocyte counts(THC)are determined,and methods for THC determination are *** 1100 hemocytes per microliter hemolymph are present in naive animals,while hemocyte density decreases dramatically shortly after wounding,indicating a role of hemocytes in response to wounding(and immune response in general).The determination of the relative abundance of each hemocyte type(differential hemocyte count,DHC)revealed that plasmatocytes are highly abundant,whereas prohemocytes and crystal cells make up only a small percentage of the circulating *** are not only the most abundant but also the professional phagocytes in *** rapidly engulf and take up bacteria both in vivo and in vitro,indicating a very potent cellular defense against invading *** bioparticles such as yeasts are also removed from circulation by phagocytosis,but slower than *** is the first analysis of the potent cellular immune response in the black soldier fly,and a first toolbox that helps to identify hemocyte(types)is presented.

关键词： black soldier fly(Hermetia ilucens) cellular immunity crystal cell hemocyte types immunity of economically imporant insects microbe phagoeytosis plasmatocyte

Liver disease in pregnancy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第8期15卷 897-906页

作者： Noel m Lee Carla W Brady Department of medicine Duke University Medical Center Durham NC 27710 United States Division of Gastroenterology Duke University Medical Center Durham NC 27710 United States

Liver diseases in pregnancy may be categorized into liver disorders that occur only in the setting of pregnancy and liver diseases that occur coincidentally with pregnancy. Hyperemesis gravidarum, preeclampsia/eclampsia, syndrome of hemolysis, elevated liver tests and low platelets (HELLP), acute fatty liver of pregnancy, and intrahepatic cholestasis of pregnancy are pregnancy-specific disorders that may cause elevations in liver tests and hepatic dysfunction. Chronic liver diseases, including cholestatic liver disease, autoimmune hepatitis, Wilson disease, and viral hepatitis may also be seen in pregnancy. management of liver disease in pregnancy requires collaboration between obstetricians and gastroenterologists/hepatologists. Treatment of pregnancy-specific liver disorders usually involves delivery of the fetus and supportive care, whereas management of chronic liver disease in pregnancy is directed toward optimizing control of the liver disorder. Cirrhosis in the setting of pregnancy is less commonly observed but offers unique challenges for patients and practitioners. This article reviews the epidemiology, pathophysiology, diagnosis, and management of liver diseases seen in pregnancy.

关键词： Liver disease Pregnancy maternal outcome Fetal outcome Cesarean section Cholestasis Viral hepatitis.

Quantum Inspired Differential Evolution with Explainable Artificial Intelligence-Based COVID-19 Detection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Systems Science & Engineering 2023年第7期46卷 209-224页

作者： Abdullah m.Basahel mohammad Yamin Department of management Information Systems Faculty of Economics and AdministrationKing Abdulaziz UniversityJeddah21589Saudi Arabia

Recent advancements in the Internet of Things(Io),5G networks,and cloud computing(CC)have led to the development of Human-centric IoT(HIoT)applications that transform human physical monitoring based on machine *** HIoT systems find use in several applications such as smart cities,healthcare,transportation,***,the HIoT system and explainable artificial intelligence(XAI)tools can be deployed in the healthcare sector for effective *** COVID-19 pandemic has become a global health issue that necessitates automated and effective diagnostic tools to detect the disease at the initial *** article presents a new quantum-inspired differential evolution with explainable artificial intelligence based COVID-19 Detection and Classification(QIDEXAI-CDC)model for HIoT *** QIDEXAI-CDC model aims to identify the occurrence of COVID-19 using the XAI tools on HIoT *** QIDEXAI-CDC model primarily uses bilateral filtering(BF)as a preprocessing tool to eradicate the *** addition,RetinaNet is applied for the generation of useful feature vectors from radiological *** COVID-19 detection and classification,quantum-inspired differential evolution(QIDE)with kernel extreme learning machine(KELm)model is *** utilization of the QIDE algorithm helps to appropriately choose the weight and bias values of the KELm *** order to report the enhanced COVID-19 detection outcomes of the QIDEXAI-CDC model,a wide range of simulations was carried *** comparative studies reported the supremacy of the QIDEXAI-CDC model over the recent approaches.

关键词： Human-centric IoT quantum computing explainable artificial intelligence healthcare COVID-19 diagnosis

Effect of RF power on the structural and optical properties of ZnS thin films prepared by RF-sputtering

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2018年第12期39卷 26-31页

作者： C.m.Samba Vall m.Chaik H.Ait Dads H.El Aakib m.Elyaagoubi m.Aggour A.Outzourhit Laboratory of Nanomaterials for Energies and Environments Faculty of Sciences Semlalia Cadi Ayyad University Laboratory of Renewable Energy and Environment Faculty of Science Kenitra Ibn Tofail University

Zinc sulphide(ZnS) thin films have grown on glass and Si substrates by reactive cathodic radio frequency(RF) sputtering. The RF power was varied in the range of 100 to 250 W, while the deposition time is set at75 min. The optical, structural, and morphological properties of these thin films have been studied. The optical properties(mainly thickness, refractive index,absorption coefficient, and optical band gap) were investigated by optical transmittance measurements in the wavelength range of ultraviolet-visible-near infrared spectroscopy and spectroscopy infrared with Fourier transform. Fourier(FT-IR) and XRD analysis indicated that all sputtering ZnS films had a single-phase with a preferred orientation along the(111) plane of the zinc sphalerite phase(ZB). The crystallite size ranged from 11.5 to 48.5 nm with RF power getting a maximum of 200 W. UV-visible measurements exhibited that the ZnS film had more than 80% transmission in the visible wavelength region. In addition, it has been observed that the band gap energy of ZnS films is decreased slightly from 3.52 to 3.29 eV, and as the RF power is increased, the film thickness increases with the speed of deposit growth. Scanning electron microscopy observations revealed the types of smooth-surfaced films. The measurements(FT-IR) revealed at wave number1118 and 465.02 cmabsorption bands corresponding to the symmetrical and asymmetric vibration of the Zn-S stretching mode. X-ray reflectometry measurements of ZnS films have shown that the density of the films is(3.9 g/cm~3) close to that of solid ZnS.

关键词： ZnS thin films by sputtered RF-sputtering ZnS ZnS buffer layer for solar cell