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Frontiers of Chemical Science and Engineering 2011年第4期5卷 477-491页

作者： Ganesh TILEKAR kiran SHINDE Kishor KALE Reshma RASKAR Abaji GAIKWAD Chemical Engineering and Process Development Division National Chemical LaboratoryPune 411008India

The capture of CO_(2) by transition metal(Mn,Ni,Co and Zn)aluminates,calcium aluminate,calcium zirconate,calcium silicate and lithium zirconate was carried out at pre-and post-combustion *** prepared metal adsorbents were characterized by X-ray diffraction(XRD),scanning electron microscope(SEM),surface area analysis and acidity/alkalinity *** different experimental variables affecting the adsorbents ability to capture CO_(2),such as the mol ratio of metal ions,the pressure of CO_(2),the exposure time and the temperature of the adsorbent were also *** zirconate captured 13.85 wt-%CO_(2) at 650℃ and 2.5 atm and calcium silicate captured 14.31 wt-%at 650℃.Molecular sieves(13X)and carbon can only capture a negligible amount of CO_(2) at high temperatures(300℃–650℃).However,the mixed metal oxides captured reasonable amount of CO_(2) at these higher *** addition,calcium aluminate,calcium zirconate,calcium silicate and lithium zirconate adsorbents captured CO_(2) at both pre and post-combustion *** trend for the amount of captured carbon dioxide over the adsorbents was calcium aluminate

关键词： captured CO_(2) pre-combustion temperature characterization calcium silicate calcium zirconate

Development and Validation of UV Spectrophotometric Method to Study Stress Degradation Behaviour of Rizatriptan Benzoate

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光谱学与光谱分析 2015年第1期35卷 137-140页

作者： Kempwade Amolkumar Taranalli Ashok Jadhav kiran KLE University's College of Phyarmacy Nehrunagar Belgaum 590010 India

Rizatriptan benzoate is a 5HT 1B/1Dreceptor agonist which is prescribed for the treatment of *** the present study new,simple,specific ultraviolet spectrophotometric method for rizatriptan benzoate was developed and *** degradation studies were carried out in acidic,alkaline and neutral pH *** absorbance maxima peak was found to be 224 nm and linearity was observed in the concentration range of 0.5~2.5μg·mL-1 with regression coefficient value of 0.998 *** method was validated and found to be *** percent recovery for rizatriptan benzoate was found to be 98.576±*** bulk drug was found to be stable in neutral and acidic pH conditions but got degraded in 1N NaOH solution.

关键词： Rizatriptan benzoate UV spectroscopy Stress degradation Validation

Exploration of IoT Nodes Communication Using LoRaWAN in Forest Environment

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Computers, Materials & Continua 2022年第6期71卷 6239-6256页

作者： Anshul Sharma Divneet Singh Kapoor Anand Nayyar Basit Qureshi kiran Jot Singh Khushal Thakur Embedded Systems&Robotics Research Group Chandigarh UniversityMohali140413PunjabIndia Graduate School Duy Tan UniversityDa Nang550000Vietnam Faculty of Information Technology Duy Tan UniversityDa Nang550000Vietnam Department of Computer Science Prince Sultan UniversityRiyadh11586Saudi Arabia

The simultaneous advances in the Internet of Things(IoT),Artificial intelligence(AI)and Robotics is going to revolutionize our world in the near *** recent years,LoRa(Long Range)wireless powered by LoRaWAN(LoRa Wide Area Network)protocol has attracted the attention of researchers for numerous applications in the IoT *** is a low power,unlicensed Industrial,Scientific,and Medical(ISM)bandequipped wireless technology that utilizes a wide area network protocol,i.e.,LoRaWAN,to incorporate itself into the network *** this paper,we have evaluated the LoRaWAN communication protocol for the implementation of the IoT(Internet of Things)nodes’communication in a forest *** outdoor performance of LoRa wireless in LoRaWAN,i.e.,the physical layer,has been evaluated in the forest area of Kashirampur Uttarakhand,***,the present paper aims towards analyzing the performance level of the LoRaWAN technology by observing the changes in Signal to Noise Ratio(SNR),Packet Reception Ratio(PRR)and Received Signal Strength Indicator(RSSI),with respect to the distance between IoT *** article focuses on estimating network lifetime for a specific set of LoRa configuration parameters,hardware selection and power *** the experimental results,it has been observed that transmissions can propagate to a distance of 300 m in the forest environment,while consuming approx.63%less energy for spreading factor 7 at 2 dBm,without incurring significant packet loss with PRR greater than 80%.

关键词： LoRa LoRaWAN IoT communication protocol wireless sensor networks packet reception ratio

Aldo-keto reductases:Role in cancer development and theranostics

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Oncology Research 2024年第8期32卷 1287-1308页

作者： SIDDAVARAM NAGINI PRATHAP REDDY KALLAMADI KRANTHI kiran KISHORE TANAGALA GEEREDDY BHANUPRAKASH REDDY World Neem Organization Mumbai400101India Department of Biochemistry ICMR-National Institute of NutritionHyderabad500007India Department of Pathology and Cell Biology Columbia University Irving Medical CenterNew York10032USA

Aldo-keto reductases(AKRs)are a superfamily of enzymes that play crucial roles in various cellular processes,including the metabolism of xenobiotics,steroids,and carbohydrates.A growing body of evidence has unveiled the involvement of AKRs in the development and progression of various *** are aberrantly expressed in a wide range of malignant *** expression of AKRs enables the acquisition of hallmark traits of cancer by activating oncogenic signaling pathways and contributing to *** have emerged as promising oncotherapeutic targets given their pivotal role in cancer development and *** of aldose reductase(AR),either alone or in combination with chemotherapeutic drugs,has evolved as a pragmatic therapeutic option for *** classes of synthetic aldo-keto reductase(AKR)inhibitors have been developed as potential anticancer agents,some of which have shown promise in clinical *** AKR inhibitors from natural sources also exhibit anticancer *** molecule inhibitors targeting speciﬁc AKR isoforms have shown promise in preclinical *** inhibitors disrupt the activation of oncogenic signaling by modulating transcription factors and kinases and sensitizing cancer cells to *** this review,we discuss the physiological functions of human AKRs,the aberrant expression of AKRs in malignancies,the involvement of AKRs in the acquisition of cancer hallmarks,and the role of AKRs in oncogenic signaling,and drug ***,the potential of aldose reductase inhibitors(ARIs)as anticancer drugs is summarized.

关键词： Aldo-keto reductases(AKRs) Aldo-keto reductase(AKR)inhibitors Cancer Drug-resistance Xenobiotics

Optical coherence tomography use in idiopathic intracranial hypertension

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Annals of Eye Science 2020年第1期5卷 45-54页

作者： kiran Malhotra Tanyatuth Padungkiatsagul Heather E.Moss Advocate Illinois Masonic Medical Center ChicagoILUSA Department of Ophthalmology Faculty of Medicine Ramathibodi HospitalMahidol UniversityBangkokThailand Department of Ophthalmology Stanford UniversityPalo AltoCAUSA Department of Neurology and Neurological Sciences Stanford UniversityPalo AltoCAUSA

Idiopathic intracranial hypertension(IIH)is a condition in which elevated pressure in the cerebrospinal fluid can lead to optic nerve head(ONH)dysfunction and subsequent visual *** are currently limited in their ability to monitor and manage this condition,as clinical symptoms and exam findings are often delayed in response to changes in intracranial *** order to find other biomarkers of disease,researchers are using imaging modalities such as optical coherence tomography(OCT)to observe microscopic changes in the eye in this *** can create 2-dimensional and 3-dimensional high definition images of the retina of the ONH and has been used to study various conditions such as glaucoma and multiple *** studies have used OCT in IIH as well,and they have shown that certain retinal layers and the ONH change in thickness and shape in both the short and long term with intracranial pressure *** is a promising modality for clinical and scientific evaluation of IIH as it is a noninvasive and practical tool to obtain in depth *** review will discuss how OCT can be used to assess a patient with IIH,both before and after treatment,along with its limitations and future applications.

关键词： Optical coherence tomography(OCT) idiopathic intracranial hypertension(IIH) pseudotumor cerebri

Efficacy and safety of local candida immunotherapy in recalcitrant warts in pediatric kidney transplantation:A case report

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World Journal of Transplantation 2023年第4期13卷 201-207页

作者： Ratna Acharya Rachel Bush Felicia Johns kiran Upadhyay Department of Pediatrics University of FloridaGainesvilleFL 32610United States Department of Pediatric Nephrology University of FloridaGainesvilleFL 32610United States

BACKGROUND Warts are common in recipients of kidney transplantation(KT).Resistant warts which are not amenable to conventional therapies may lead to significant *** data exists on safety and efficacy of local immunotherapy among immunocompromised KT *** SUMMARY We report a seven-year-old child who presented with recalcitrant plantar periungual warts in the early KT *** consisted of tacrolimus,mycophenolate and *** to failure of conventional anti-wart therapies,he was treated with two sessions of intralesional(IL)candida immunotherapy along with liquid nitrogen cryotherapy leading to complete resolution of the ***,de novo BK viremia was seen about three weeks following the last candida *** required reduction of immunosuppression and other anti-BK viral *** function remained stable but there were donor specific antibodies *** also was elevated level of plasma donor derived cell-free DNA.A pneumocystis jirovecii pneumonia occurred ten months following completion of immunotherapy that was successfully treated with *** this ten-month follow-up period,there have been no recurrence of warts,and transplant kidney function has remained *** Stimulation of cell-mediated immunity against the human papilloma virus induced by the IL candida immunotherapy is thought to be a cause for wart *** this therapy,whether it is necessary to augment the immunosuppression to prevent rejection is unclear as that may come with a risk of infectious ***,prospective studies in pediatric KT recipients are needed to explore these important issues.

关键词： Warts Kidney transplantation Candida Immunotherapy Pediatric Case report

Combustion performance of hybrid rocket fuels loaded with MgB_(2)and carbon black additives

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Propulsion and Power Research 2023年第2期12卷 212-226页

作者： Yash Pal Sasi kiran Palateerdham Sri Nithya Mahottamananda Subha Sivakumar Antonella Ingenito School of Aeronautical Sciences Hindustan Institute of Technology and ScienceChennai 603103India School of Aerospace Engineering University of Rome“La Sapienza”00138RomeItaly Department of Aerospace Engineering BS Abdur Rahman Crescent Institute of Science&TechnologyChennai 600048India

Paraffin-based fuel has a great potential for several innovative missions,including space tourism,due to its safety,low environmental impact,high performance and low *** the fact that liquefying solid fuels increases the regression rate of hybrid rocket motors,incorporating energetic materials into solid fuel can still improve the *** objective and scope of this study is to increase the performance characteristics of the paraffin-based fuel by using magnesium diboride(MgB_(2))and carbon black(CB)*** cylindricalport fuel grains were manufactured with various additives percentages in mass(wt%:CB-2%and MgB_(2)-10%)and tested using a laboratory-scale ballistic hybrid motor under gaseous *** mechanical performance results revealed that adding CB and MgB_(2) improved the ultimate strength and elastic modulus of paraffin-based *** addition of these fillers increased the hardness of fuel by developing a strong interaction in the paraffin ***(TG)results showed that CB inclusion improved the thermal stability of the paraffin *** average regression rates of fuels loaded with CB and MgB_(2) were 32%and 52%higher than those of unmodified paraffin wax,*** characteristic velocity efficiency was found in the range of 68%e79%at an O/F ratio of *** MgB_(2) oxidation/combustion in the paraffin matrix was described by a four-step oxidation process ranging from 473 K to 1723 ***,a combustion model of MgB_(2) in the paraffin matrix was proposed,and four-step oxidation processes were discussed in detail.

关键词： Hybrid rocket Paraffin wax Regression rate Magnesium diboride Mechanical properties

Call for accurate statistical data to solve snakebite conundrum in India

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Asian Pacific Journal of Tropical Medicine 2020年第4期13卷 141-142页

作者： Saurabh Bhargava kiran Kumari R.K.Sarin Rajvinder Singh Department of Genetics M.D.UniversityRohtak-124001 HaryanaIndia Andhra Pradesh Forensic Science Laboratory MangalgiriGunturAndhra Pradesh-522004India

After a prolonged debate and discussion,the World Health Organization(WHO)relisted'snakebite'under Category'A'of'Neglected Tropical Diseases'(NTDs)in June 2017 hoping to diminish its burden on ***,in March 2009,WHO added snakebite to its official list of NTDs but later downgraded to'Other Neglected Conditions',a list reduced in importance[1,2].Obviously,the recent inclusion of snakebite in NTDs was due to the estimation of huge toll of deaths due to snake envenomation in tropical countries as supported by the multiple *** inclusion will expedite the process of developing better management protocols and infusing funds for such affected countries.

关键词： snake listed graded

Y chromosome microdeletions in azoospermic patients with Klinefelter's syndrome

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Asian Journal of Andrology 2006年第1期8卷 81-88页

作者： Anurag Mitra Rima Dada Rajeev Kumar Narmada Prasad Gupta kiran Kucheria Satish Kumar Gupta Gamete Antigen Laboratory National Institute of ImmunologyAruna Asaf Ali MargNew Delhi 110067India Department of Anatomy Department of Urology All India Institute of Medical SciencesAnsari NagarNew Delhi 110029India

Aim： To study the occurrence of Y chromosome microdeletions in azoospermic patients with Klinefelter＇s syndrome （KFS）. Methods： Blood and semen samples were collected from azoospermic patients with KFS （n = 14） and a control group of men of proven fertility （n = 13）. Semen analysis was done according to World Health Organization （WHO） guidelines. Blood samples were processed for karyotyping, fluorescent in situ hybridization （FISH） and measurement of plasma follicle stimulating hormone （FSH） by radioimmunoassay. To determine Y chromosome microdeletions, polymerase chain reaction （PCR） of 16 sequence tagged sites （STS） and three genes （DFFRY, XKRY and RBM1 Y） was performed on isolated genomic DNA. Testicular fine needle aspiration cytology （FNAC） was done in selected cases. Results： Y chromosome microdeletions spanning the azoospermia factor （AZF）a and AZFb loci were found in four of the 14 azoospermic patients with KFS. Karyotype and FISH analysis revealed that, of the four cases showing Y chromosome microdeletion, three cases had a 47,XXY/46,XY chromosomal pattern and one case had a 46,XY/47,XXY/48,XXXY/48,XXYY chromosomal pattern. The testicular FNAC of one sample with Y chromosome microdeletion revealed Sertoli cell-only type of morphology. However, no Y chromosome microdeletions were observed in any of the 13 fertile men. All patients with KFS had elevated plasma FSH levels. Conclusion： Patients with KFS may harbor Y chromosome microdeletions and screening for these should be a part of their diagnostic work-up, particularly in those considering assisted reproductive techniques. （Asian JAndrol 2006 Jan; 8： 81-88）

关键词： azoospermia azoospermia factor follicle stimulating hormone Klinefelter's syndrome Y chromosome microdeletion

The Ability of Some Aquatic and Terrestrial Plants to Purify Domestic Wastewater

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Phyton-International Journal of Experimental Botany 2023年第8期92卷 2245-2260页

作者： Abida Kausar Noreen Zahra Humaira kiran Sadia Asim Abid Raza Ali Raza Department of Botany Government College Women UniversityFaisalabad38000Pakistan Department of Botany University of AgricultureFaisalabad38040Pakistan Department of Chemistry Government College Women UniversityFaisalabad38000Pakistan Department of Agronomy Muhammad Nawaz Shareef University of AgricultureMultan66000Pakistan College of Agriculture Fujian Agriculture and Forestry UniversityFuzhou350002China

The study aimed to evaluate the ability of some terrestrial and aquatic plants for wastewater puriﬁ*** plants can remove pollutants from wastewater by consuming and accumulating various contaminants in different parts of *** aquatic and terrestrial plants(Rosa sinensis,Typha latifolia,Ocimm bacilicum,Azolla pinnata,and Salvinia molesta)which have the ability to decrease water pollution were utilized in this *** capability offive different species of plants was investigated by measuring chemical oxygen demand(COD),biological oxygen demand(BOD),electrical conductivity(EC),total dissolved solids(TDS),and pH of the *** this research,some aquatic and terrestrial plants were transplanted in wastewater plastic pots containing domestic wastewater with different ratios of 50%and 100%.Then,after 30 days,the physiological and biochemical parameters of plants were calculated to observe the effect of wastewater on *** revealed higher chlorophyll and carotenoids in typha plants treated with 100%*** highest percentage of elimination in BOD(65%),COD(27%),TDS(72%),EC(83%),and pH(6.8%)was noted with the use of typha and ***,total soluble sugars,total free amino acids,and total proteins were found maximum in the hibiscus plant as compared to the other plants under 100%and 50%domestic wastewater treatment,while typha and ocimum showed lower values of these parameters irrespective of wastewater ***,the COD,BOD,TDS,EC,and pH trend was higher in 100%wastewater as compared to 50%*** into account the accumulation capacity of the tested plants especially typha can be efﬁciently used for the treatment of domestic wastewater.

关键词： Biological oxygen demand chemical oxygen demand domestic wastewater aquatic plants terrestrial plants