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Journal of Materials Science and Chemical Engineering 2017年第1期5卷 15-25页

作者： Junji yamanaka Shigenori Inoue Keisuke Arimoto Kiyokazu Nakagawa kentarou Sawano Yasuhiro Shiraki Atsushi Moriya Yasuhiro Inokuchi Yasuo Kunii Center for Crystal Science and Technology University of Yamanashi Kofu Japan Advanced Research Laboratories Tokyo City University Tokyo Japan Hitachi Kokusai Electric Inc. Toyama Japan

Strained Si and its related materials, such as strained SiGe and strained silicon-carbon alloy (Si-C), are receiving tremendous interest due to their high carrier mobility. In this study we carry out a basic investigation of the change in microstructure of ion-implanted Si-C solid solution caused by rapid thermal annealing, because it is very important to realize a field-effect transistor made of this new material. The microstructures of arsenic-ion-, boron-ion-, and silicon-ion-implanted Si0.99C0.01 specimens upon thermal annealing are observed using transmission electron microscopy, and it is revealed that the rate of solid-state crystallization of ion-implanted Si-C is slower than that of the ion-implanted Si.

关键词： Strained Heterodevice Silicon-Carbon Alloy Ion Implantation Transmission Electron Microscopy

Morbidity of Open Saphenous Vein Harvesting after Preoperative Ultrasonic Mapping

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Open Journal of Thoracic Surgery 2015年第1期5卷 4-9页

作者： Susumu Isoda Tamizo Kimura Katsunori Tanaka Kenji Nishimura Nozomu yamanaka Shin-ichi Taguchi Keiji Uchida Norihisa Karube Kiyotaka Imoto Department of Cardiovascular Surgery Yokohama City University Medical Center Yokohama Japan Department of Cardiovascular Surgery National Defense Medical College Tokorozawa Japan

Preoperative echography of a saphenous vein graft (SVG) was studied. In 58 cases of consecutive coronary artery bypass grafting, 31 patients underwent SVG echography. Preoperative assessment revealed vein caliber, branching, or varicose saphenous veins. The location of the saphenous vein was marked. Saphenous veins were harvested by the open harvest technique, and the caliber of the veins and the availability of the anastomosis device were recorded. Postoperative morbidity was recorded. Preoperative findings revealed that four (6.5%) of 62 femoral saphenous veins were estimated as “not graftable” because of being a varicose vein or having a small caliber. Seven of 32 lower saphenous veins were estimated as “not graftable”. The mean discrepancy of the caliber was 0.6 mm undersized with preoperative estimation. During harvesting, one of 31 patients had a wrong marking. We were able to use all harvested veins. The morbidity of saphenous harvesting was observed in two (6.5%) of 31 patients. One patient whose marking was wrong had minor skin necrosis. Another patient experienced a hematoma because of the excess effect of warfarin. Preoperative ultrasonic mapping of the saphenous vein reduced useless harvesting, provided information concerning anastomosis device availability, and seemed to reduce morbidity because dissection can be minimal.

关键词： Saphenous Vein Ultrasonic Mapping Coronary Artery Bypass Grafting

棋盘格子图案CCD彩色摄象管的器件结构和空间频谱

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半导体光电 1979年第1期 38-49页

作者： SHIGEYUKI OCHI SEISUKE yamanaka 孙志君

为了发展高分辨率的家用彩色摄象管,提出了一种新奇的图象处理技术和电荷耦合器件(CCD)结构,从而减小了芯片尺寸,且放宽了对光刻的要求.CCD 摄象管的分辨率受寄生误差的限制,此寄生误差与光敏面上的空间分立取样有关.排列成两维面心长... 详细信息

为了发展高分辨率的家用彩色摄象管,提出了一种新奇的图象处理技术和电荷耦合器件(CCD)结构,从而减小了芯片尺寸,且放宽了对光刻的要求.CCD 摄象管的分辨率受寄生误差的限制,此寄生误差与光敏面上的空间分立取样有关.排列成两维面心长方格子的光敏列阵和三个CCD 中的空间补偿技术,避免了伴随寄生误差而产生的不希望的信号载流子.为了减小寄生效应,提出了一种图象垂直相关的新的信号处理技术。在一频谱空间,对这种新的图象处理技术进行了理论分析.用棋盘格子式图案传感单元的弯曲转移 CCD,成功地实现了具有面心长方格子式图案的光敏列阵。这种新的器件结构,放宽了对光刻的要求,并改进了图象质量.与相同象素日普通 CCD 摄象管相比,采用这种弯曲转移的 CCD 结构和新的图象处理技术,使彩色摄象管的分辨率提高到25倍.理论上,分辨率还可提高到三倍或四倍.

关键词：图象处理棋盘格摄象计算机应用 CCD 棋盘分辨率鉴别率器件结构

Impact of infection in hospitalized cirrhotic patients in a university hospital

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Open Journal of Gastroenterology 2012年第3期2卷 124-130页

作者： Tiago dos Santos Ferreira Tiago Sevá-Pereira Jazon Romilson de Souza Almeida Milena Fioravante Ademar yamanaka Elza Cotrim Soares Department of Internal Medicine Faculty of Medical Sciences University of Campinas (UNICAMP) Campinas Brazil Gastrocenter University of Campinas (UNICAMP) Campinas Brazil

Background: Infection increases the morbidity and mortality in liver cirrhosis patients. The aim of this study was to investigate the impact of infection related to survival and risk factors for death in adult patients with liver cirrhosis in a university hospital. Methods: In a retrospective cohort study of Brazilian hospitalized cirrhotic patients, medical records data were analysed, and all patients who have had one or more confirmed bacterial infection during admission were se-ected for the study. Also, some data as biochemical investigation, Child score, MELD estimation, and evolution and death event were included. Statistical analysis: chi-square, Fisher and Mann-Whitney tests were used. Uni and multivariate analysis were performed, according to Cox regression model. The significant statistical level was p 2.5 mg/dl had increased the risk of death of 4.1, 3.2 and 3.2, respectively. Conclusion: Bacterial infections in hospitalized cirrhotic patients deserve special care, mainly spontaneous bacterial peritonitis, and also patients whose hiponatremia, upper gastrointestinal bleeding, high levels of cre-atinine and MELD high score are found.

关键词： Infection Survival Curve Mortality Liver Cirrhosis

Surface Roughness of SiGe/Si(110) Formed by Stress-Induced Twins and the Solution to Produce Smooth Surface

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Journal of Materials Science and Chemical Engineering 2018年第1期6卷 25-31页

作者： Junji yamanaka Mai Shirakura Chiaya Yamamoto Naoto Utsuyama Kei Sato Takane Yamada Kosuke O. Hara Keisuke Arimoto Kiyokazu Nakagawa Center for Instrumental Analysis University of Yamanashi Kofu Japan Center for Creative Technology University of Yamanashi Kofu Japan Center for Crystal Science and Technology University of Yamanashi Kofu Japan

Lattice-strained Si thin films grown onto SiGe(110)/Si(110) are attracting because of their potential to realize high-speed transistors. In this study we observe surface morphology of Si/SiGe/Si(110) using scanning electron microscopy and we also observe microstructure of the identical position using cross-sectional transmission electron microscopy. These results reveal that crossing of stress-induced twins causes remarkable surface roughness. We propose using vicinal substrate to avoid this phenomenon and our successive experimental results are shown in this paper.

关键词： Strained Si SiGe(110) Stress-Induced Twin Transmission Electron Microscopy

Off-Pump Multilayered Sutureless Repair for a Left Ventricular Blowout Rupture after Aortic Dissection Repair

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Open Journal of Thoracic Surgery 2015年第1期5卷 10-14页

A left ventricular (LV) free wall rupture is a highly lethal condition. A 75-year-old female who experienced chest pain was diagnosed as having an acute aortic dissection Stanford type A and underwent emergent surgery. Under cardiopulmonary bypass with LV venting through the right superior pulmonary vein, a proximal aortic stamp was formed. The patient was cooled, selective antegrade brain perfusion was performed, and a hemiarch repair was performed. After the patient was transferred to the intensive care unit, her blood pressure suddenly fell to 50 mmHg. She had a blowout rupture in the left ventricular anterolateral free wall. Since the bleeding hall was not large and the damage to the surrounding left ventricular tissue was not very wide, an off-pump multilayered sutureless repair was performed by using three layers of collagen fleece squares with fibrinogen-based impregnation (TachoComb;CSL Behring, Tokyo, Japan) and three layers of gelatin-resorcin-formalin glue reinforced by an equine pericardial patch (Xenomedica;Edwards Lifesciences, LLC, Irvine, CA). The blow-out rupture seemed to be caused by perioperative myocardial infarction generated by the compression of the left ventricular vent to the LV lateral wall. The patient was free from re-rupture or aneurysm enlargement. The thickness of the hemostatic material seemed to help control the bulging of the aneurysm and to prevent further LV aneurysm enlargement and re-rupture.

关键词： Blowout Cardiac Rupture Sutureless Repair Aortic Dissection TachoComb

Safety and Efficacy of Once-Daily Administration of Mycophenolate Mofetil in Kidney Transplant Patients—A New Treatment Option for Non-Adherence

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Journal of Biomedical Science and Engineering 2014年第10期7卷 788-791页

作者： Naotsugu Ichimaru Kazuaki yamanaka Taigo Kato Yoichi Kakuta Toyofumi Abe Jun-ya Kaimori Ryoichi Imamura Norio Nonomura Shiro Takahara Department of Advanced Technology for Transplantation Osaka University Graduate School of Medicine Suita Japan Department of Specific Organ Regulation (Urology) Osaka University Graduate School of Medicine Suita Japan

Non-adherence to immunosuppressive therapy is associated with reduced graft survival. Fifteen long-term follow up kidney transplant patients with stable post-transplant clinical courses were enrolled in the study. All patients were prescribed to tacrolimus prolonged release, mycophenolate mofetil (MMF) and corticosteroid at the time of enrolment. Twice-daily administration of MMF was then converted to a single daily dose. As a result, all immunosuppressive agents were administered simultaneously at one time in the morning. The daily total doses of the three immunosuppressants were identical during the study period. No acute rejection or adverse event was observed during the study period. Blood urea nitrogen and estimated glomerular filtration rate did not change significantly after conversion to once-daily administration. The blood tacrolimus trough level and the Mycophenolic acid (MPA) trough level also did not change significantly after conversion to once-daily administration. Interestingly, the meanmedian MPA trough level remained >3 μg/ml even after conversion to once-daily administration. A sufficient plasma MPA level was maintained after conversion to once-daily administration, and no acute rejection was observed during the study period. To our knowledge, this study is the first to report that the plasma MPA concentration can be maintained after once-daily administration of MMF in long-term kidney transplant patients. Once-daily administration of immunosuppressive agents may improve long-term graft survival because of better treatment adherence due to the reduced dosing frequency. The safety or efficacy of conversion to once-daily administration of MMF should be evaluated in a future randomized controlled large-scale clinical study.

关键词： Once-Daily Administration Mycophenolate Mofetil Treatment Adherence

Fibrin Sealant Patch to Treat Dialysis-Associated Hemorrhagic Pericarditis

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Open Journal of Thoracic Surgery 2015年第1期5卷 1-3页

作者： Susumu Isoda Tamizo Kimura Katsunori Tanaka Kenji Nishimura Nozomu yamanaka Shin-ichi Taguchi Norihisa Karube Keiji Uchida Kiyotaka Imoto Department of Cardiovascular Surgery Yokohama City University Medical Center Yokohama Japan Department of Cardiovascular Surgery National Defense Medical College Tokorozawa Japan

A 73-year-old male patient with a 3-year history of hemodialysis was admitted for the treatment of pericardial effusion. Echocardiography suggested a diagnosis of effusive pericarditis. Pericardiocentesis was performed several times. Six weeks after the admission, the patient developed cardiac tamponade. Surgical pericardiotomy showed the epicardium had a diffuse shaggy and hemorrhagic surface. To control diffuse oozing, fibrin sealant patches (Tachosil;CSL Behring, Tokyo, Japan) were attached to the epicardium. Oozing was then controlled.

关键词： Fibrin Sealant Patch Hemodialysis Hemorrhage Pericarditis

大火热辐射对车辆用材料燃烧性能影响的定量研究

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国外铁道机车与动车 2021年第3期 43-48页

作者： [日]Sho yamanaka 刘志荣(译) 张霓虹(校) 不详

在日本,根据相关条例对铁道车辆用材料按本国标准进行防火试验,根据其性能对材料分级。制定了有助于铁道车辆防火安全的防火试验标准。然而,标准防火试验中用的热辐射相对较低,一些标准只是质性的。过去几年发生的多起严重火灾表明,在... 详细信息

在日本,根据相关条例对铁道车辆用材料按本国标准进行防火试验,根据其性能对材料分级。制定了有助于铁道车辆防火安全的防火试验标准。然而,标准防火试验中用的热辐射相对较低,一些标准只是质性的。过去几年发生的多起严重火灾表明,在标准防火试验中低估了一些试验条件。这说明进行定量研究来检测大火热辐射对车辆用材料燃烧性能的影响极为重要。为此,进行了锥形量热仪防火试验来研究大火热辐射对车辆用的一系列产品的影响。

关键词：铁路火灾燃烧性能锥形量热仪防火试验

Ohmic Contact Formation for n+4H-SiC Substrate by Selective Heating Method Using Hydrogen Radical Irradiation

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Journal of Materials Science and Chemical Engineering 2017年第1期5卷 35-41页

作者： Tetsuji Arai Kazuki Kamimura Chiaya Yamamoto Mai Shirakura Keisuke Arimoto Junji yamanaka Kiyokazu Nakagawa Toshiyuki Takamatsu Masaaki Ogino Masaaki Tachioka Haruo Nakazawa Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Kofu Japan SST Inc. Yachiyo Japan Fuji Electric Co. Ltd. Matsumoto Japan

We developed an apparatus for producing high-density hydrogen plasma. We confirmed that the temperatures of transition-metal films increased to above 800?C within 5 s when they were exposed to hydrogen plasma formed using the apparatus. We applied this phenomenon to the selective heat treatment of W/Ni films deposited on n+4H-SiC wafers and formed nickel silicide electrodes. To utilize this method, we can perform the nickel silicidation process without heating the other areas such as channel regions and improve the reliability.

关键词： Selective Heating Nickel Silicide Electrode Hydrogen Plasma Ohmic Contact SiC