Impact of infection in hospitalized cirrhotic patients in a university hospital
Impact of infection in hospitalized cirrhotic patients in a university hospital作者机构：Department of Internal Medicine Faculty of Medical Sciences University of Campinas (UNICAMP) Campinas Brazil Gastrocenter University of Campinas (UNICAMP) Campinas Brazil
出 版 物：《Open Journal of Gastroenterology》 (肠胃病学期刊（英文）)
年 卷 期：2012年第2卷第3期
页 面：124-130页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Infection Survival Curve Mortality Liver Cirrhosis
摘 要：Background: Infection increases the morbidity and mortality in liver cirrhosis patients. The aim of this study was to investigate the impact of infection related to survival and risk factors for death in adult patients with liver cirrhosis in a university hospital. Methods: In a retrospective cohort study of Brazilian hospitalized cirrhotic patients, medical records data were analysed, and all patients who have had one or more confirmed bacterial infection during admission were se-ected for the study. Also, some data as biochemical investigation, Child score, MELD estimation, and evolution and death event were included. Statistical analysis: chi-square, Fisher and Mann-Whitney tests were used. Uni and multivariate analysis were performed, according to Cox regression model. The significant statistical level was p 2.5 mg/dl had increased the risk of death of 4.1, 3.2 and 3.2, respectively. Conclusion: Bacterial infections in hospitalized cirrhotic patients deserve special care, mainly spontaneous bacterial peritonitis, and also patients whose hiponatremia, upper gastrointestinal bleeding, high levels of cre-atinine and MELD high score are found.
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