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Plantar Spitz Nevus Resembling Malignant Melanoma: Description of Immunohistochemical Findings

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Case Reports in Clinical Medicine 2023年第6期12卷 202-206页

作者： Karen Fukushi Tomohisa Fukui Hajime nakano Daisuke Sawamura Department of Dermatology Hirosaki University Graduate School of Medicine Hirosaki Japan

Spitz nevus (SN) is predominantly distributed throughout the lower extremities, while an acral location is rare. Since SN occasionally resembles the clinicopathological presentation of malignant melanoma (MM), it presents a diagnostic challenge, especially on glabrous skin. Past reports suggest that several genetic aberrations are associated with specific clinicopathological subtypes of melanocytic tumors. Immunohistochemistry can provide a clue to the presence or absence of a molecular aberration typical of Spitz tumors. We describe a case of a plantar SN with genetic analysis, including anaplastic lymphoma kinase (ALK), ROS proto-oncogene 1 (ROS1), BRAF (V600E) protein, and BRCA1-associated protein-1 (BAP1). However, we were not able to detect a characteristic gene aberration. To the best of our knowledge, no genetic aberrations in plantar SN cases have been reported. A comprehensive understanding of tumor genomics is expected to play an essential role in the classification of melanocytic tumors. Further genetic research on plantar SN is required to establish new criteria for distinguishing between SN and MM.

关键词： Spitz Nevus Plantar Malignant Melanoma

Design and Analysis of Compact Directionally Coupled Bistable Laser Diodes

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光学学报 2003年第S1期23卷 333-334页

作者： Mitsuru Takenaka Yoshiaki nakano JST-CREST Research Center for Advanced Science and Technology University of Tokyo 7-3-1 Kongo Bunkyo-ku Tokyo 113-8656 JapanJST-CREST Research Center for Advanced Science and Technology University of Tokyo 7-3-1 Kongo Bunkyo-ku Tokyo 113-8656 Japan

A compact optical flip-flop with a directional coupler has been designed and analyzed. Using a narrow gap directional coupler, we have predicted the device length could be reduced down to 500μm from 1300μm.

关键词： length on as be BLD Design and Analysis of Compact Directionally Coupled Bistable Laser Diodes of have BPM than DC

Autonomous reinforcement learning agent for chemical vapor deposition synthesis of quantum materials

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npj Computational Materials 2021年第1期7卷 983-991页

作者： Pankaj Rajak Aravind Krishnamoorthy Ankit Mishra Rajiv Kalia Aiichiro nakano Priya Vashishta Argonne Leadership Computing Facility Argonne National LaboratoryArgonneILUSA Collaboratory for Advanced Computing and Simulations University of Southern CaliforniaLos AngelesCAUSA Department of Chemical Engineering&Materials Science University of Southern CaliforniaLos AngelesCAUSA Department of Physics&Astronomy University of Southern CaliforniaLos AngelesCAUSA Department of Computer Science University of Southern CaliforniaLos AngelesCAUSA

Predictive materials synthesis is the primary bottleneck in realizing functional and quantum *** for synthesis of promising materials are currently identified by time-consuming trial and error and there are no known predictive schemes to design synthesis parameters for *** use offline reinforcement learning(RL)to predict optimal synthesis schedules,i.e.,a time-sequence of reaction conditions like temperatures and concentrations,for the synthesis of semiconducting monolayer MoS2 using chemical vapor *** RL agent,trained on 10,000 computational synthesis simulations,learned threshold temperatures and chemical potentials for onset of chemical reactions and predicted previously unknown synthesis schedules that produce well-sulfidized crystalline,phase-pure *** model can be extended to multi-task objectives such as predicting profiles for synthesis of complex structures including multi-phase heterostructures and can predict long-time behavior of reacting systems,far beyond the domain of molecular dynamics simulations,making these predictions directly relevant to experimental synthesis.

关键词： materials synthesis synthesis

Countermeasure Against Regenerative and Forced Chatter of Flexible Workpieces in Milling Processs Using Bi-directional Excitation

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Transactions of Nanjing University of Aeronautics and Astronautics 2018年第1期35卷 10-19页

作者： nakano Yutaka De Silva Amal Dilanka Takahara Hiroki Akiyama Yu Department of Mechanical Engineering School of EngineeringTokyo Institute of Technology Department of Mechanical Sciences and Engineering Graduate School of Science and EngineeringTokyo Institute of Technology

A novel extended methodology for chatter suppression in milling process by applying external forced vibrations to the workpiece in two orthogonal directions which are the feed and cross-feed *** the regenerative and forced chatter suppression during the milling process of flexible workpieces are ***,the workpiece is subject to a sinusoidal periodic force in the feed direction to disrupt the regenerative ***,to minimize the forced chatter,the workpiece is subject to the periodic excitation force in cross-feed *** force is proportional to the magnitude of the estimated cutting force in cross-feed direction and has a phase opposite to the cutting force to minimize the vibration *** effectiveness of the proposed method is evaluated numerically and experimentally,for the spindle speed located in both the local minima and local maxima of the stability lobe *** numerical simulations indicate significant suppression effect in terms of vibration amplitudes,resulting in suppression of both the regenerative chatter and the forced *** were conducted by using a workpiece-mounted active stage composed of flexure hinges and driven by piezoelectric *** experimental results agree qualitatively with the numerical *** proposed method indicates a remarkable vibration reduction effect for both regenerative and forced chatters.

关键词： self-excited vibration vibration control regenerative chatter forced chatter milling

Effect of transition metaldoping under reducing calcination atmosphere on photocatalytic property of TiO_2 immobilized on SiO_2 beads

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Journal of Environmental Sciences 2013年第7期25卷 1419-1423页

作者： Rumi Chand Eiko Obuchi Katsumi Katoh Hom Nath Luitel Katsuyuki nakano Department of Chemical Engineering Fukuoka University Department of Applied Chemistry Saga University

TiO2 immobilized on SiO2 （TiO2 /SiO2 ） have been prepared by sol-gel method and various ions of transition metals （Cr3＋ , Co2＋ , Ni2＋ , Cu2＋ , and Zn2＋）weredoped on the photocatalyst usingwet impregnation method under reducing calcination atmosphere. The photocatalytic activity of metaldoped TiO2 /SiO2 towards phenoldegradation under black light irradiationwere investigated and comparedwith undoped TiO2 /SiO2 . The results showed that the photoresponse of Cu2＋ and Zn2＋doped TiO2 /SiO2were larger than undoped TiO2 /SiO2 , indicating that the photogenerated carrierswere separated more efficiently in Cu2＋ and Zn2＋doped TiO2 /SiO2 . The reactivitywas in the order of Cu2＋〉 Zn2＋〉 Ni2＋〉 Cr3＋〉 Co2＋ . Thedifferent photoreactivitywas ascribed to combine effect of thedifferent ionic radii and photocorrison tendency of thedopants. The samplewas also characterized by surface analytical methods such as X-raydiffraction, scanning electron micrograph/electrondispersive X-ray analyzer and UV-Vis absorption spectrum.

关键词： heterogeneous photocatalysis TiO2 SiO2 beads metaldoping photodecomposition

Efects of amine, amine salt and amide on the behaviour of carbon dioxide absorption into calcium hydroxide suspension to precipitate calcium carbonate

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Journal of Environmental Sciences 2013年第12期25卷 2507-2515页

作者： Wittaya Chuajiw Mitsuru nakano Kazumasa Takatori Toshiya Kojima Yoshiki Wakimoto Yoshiaki Fukushima Toyota Technological Institute 2-12-1 HisakataTempaku-kuTenpaku Moon Chome Toyota Central R&D Labs. Inc. Yokomichi Aisin Seiki Co. Ltd.2-1Asahi-machi

The amount of carbon dioxide （CO2） absorption and calcium ion （Ca^2＋） concentration besides the pH of aqueous solution were observed during the COz absorption to precipitate calcium carbonate （CaCO3） from calcium hydroxide （Ca（OH）2）. A reaction rate-limiting effect of an amount of CO2 absorption without any organic additives in the early stage of the precipitation was observed, which was attributed to an interruption effect of bicarbonate ion （HCO3） on the precipitation of CaCO3. The improvement for the reaction rate was achieved not only by amine additives but also by neutral additives such as ε-caprolactam or amine salt. When the hexamethylene diamine was dissolved in the solution, successive change of crystal forms of CaCO3 aragonite to calcite in aqueous suspensions, confirmed by Ca^2＋ concentration change and X-ray diffraction, was concluded that a local environment around the amine group in aqueous solution and an interaction of the diamine with precipitated CaCO3 particles were important factors for these reactions.

关键词： carbon dioxide absorption calcium carbonate precipitation local functional group interaction

Microstructure,hardening and deuterium retention in CVD tungsten irradiated with neutrons at temperatures of defect recovery stagesⅡandⅢ

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Tungsten 2022年第3期4卷 248-260页

作者： Xiao-Ou Yi Tatsuya Kuwabara Vladimir KhAlimov Yu-Feng Du Wen-Tuo Han Ping-Ping Liu Bin-You Yan Jiu-Peng Song kenta Yoshida Takeshi Toyama Fa-Rong Wan Somei Ohnuki Yuji Hatano Yasuyoshi Nagai School of Materials Science and Engineering University of Science and Technology BeijingBeijing100083China Graduate School of Engineering Nagoya UniversityFuro-choChikusa-kuNagoya464-8063Japan Frumkin Institute of Physical Chemistry and Electrochemistry Russian Academy of SciencesMoscow119071Russia Institute for Materials Research Tohoku UniversityNarita-cho 2145-2OaraiIbaraki311-1313Japan Xiamen Tungsten Co.Ltd. Xiamen361021China School of Materials Science and Engineering Xihua UniversityChengdu610039China Hydrogen Isotope Research Center University of ToyamaToyama930-8555Japan

Samples of ultra-high-purity tungsten prepared using chemical vapour deposition(CVD)technique were irradiated with neutrons at temperatures T_(irr)=373-483 K(stage Ⅱ of defect recovery)and T_(irr)=573-673 K(stage Ⅲ)up to 0.15 displacements per atom(dpa)in the Belgian reactor(BR2).The study of the microstructure of neutron-damaged samples using transmission electron microscopy(TEM)revealed visible defects with a predominance of dislocation *** an increase in the neutron irradiation temperature,the spatial distribution of the loops acquired pronounced inhomogeneity,and their average size moderately *** and voids were not ***-induced hardening was found and a linear correlation was obtained between Vickers microhardness and nanohardness for undamaged and neutron-irradiated CVD-W *** of tungsten with neutrons led to a significant increase in the retention of deuterium,which accumulated mainly in vacancy-type ***,the influence of the columnar grain structure in low-dose neutron-irradiated tungsten seemed to be non-trivial upon deuterium retention.

关键词： CVD-W Neutron irradiation Microstructure Hardening Deuterium retention

Structural Analysis of a New Phase of BaNdMnO_4

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Journal of Rare Earths 2007年第S1期25卷 1-3页

作者： Hiromi nakano Norikatsu Kawabata Hirohisa Satoh Naoki Kamegashira Ryukoku University SetaOtsu520-2194Japan Toyohasi University of Technology 441-8580Japan

Single crystal of BaNdMnO4 with I4/mmm was synthesized by a floating zone method. A new phase of BaNdMnO4 was obtained by annealing the single crystal in a reducing atmosphere at 573 K for 10 d. The structural change was analyzed by four-circle X-ray diffractometry and transmission electron microscopy. The new phase has an orthorhombic unit cell (Fmmm) of a=0.5486(2) nm, b=0.5484(2) nm, and c=1.3059(2) nm.

关键词： rare earth manganite structure transmission electron microscopy X-ray diffractometry

Active control of friction by transverse oscillations

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Friction 2019年第1期7卷 74-85页

作者： J.BENAD K.nakano V.L.POPOV M.POPOV Technische Universit?t Berlin Yokohama National University National Research Tomsk Polytechnic University National Research Tomsk State University

The present paper is devoted to a theoretical analysis of sliding friction under the influence of in-plane oscillations perpendicular to the sliding direction. Contrary to previous studies of this mode of active control of friction, we consider the influence of the stiffness of the tribological contact in detail and show that the contact stiffness plays a central role for small oscillation amplitudes. In the present paper we consider the case of a displacement-controlled system, where the contact stiffness is small compared to the stiffness of the measuring system. It is shown that in this case the macroscopic coefficient of friction is a function of two dimensionless parameters— a dimensionless sliding velocity and dimensionless oscillation amplitude. In the limit of very large oscillation amplitudes, known solutions previously reported in the literature are reproduced. The region of small amplitudes is described for the first time in this paper.

关键词： sliding friction in-plane oscillation contact stiffness coefficient of friction active control of friction