检索结果-南通市图书馆

Recent Advances in Japanese Fisheries Science in the Kuroshio-Oyashio Region through Development of the FRA-ROMS Ocean Forecast System: Overview of the Reproducibility of Reanalysis Products

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Open Journal of Marine Science 2017年第1期7卷 62-90页

作者： Hiroshi Kuroda Takashi Setou Shigeho Kakehi Shin-ichi Ito Takeshi Taneda Tomonori Azumaya Denzo Inagake Yutaka Hiroe kenji Morinaga Makoto Okazaki Takashi Yokota Takeshi Okunishi Kazuhiro Aoki Yugo Shimizu Daisuke Hasegawa Tomowo watanabe Hokkaido National Fisheries Research Institute Japan Fisheries Research and Education Agency Kushiro Japan National Research Institute of Fisheries Science Japan Fisheries Research and Education Agency Yokohama Japan Tohoku National Fisheries Research Institute Japan Fisheries Research and Education Agency Shiogama Japan Atmosphere and Ocean Research Institute University of Tokyo Kashiwa Japan Seikai National Fisheries Research Institute Japan Fisheries Research and Education Agency Nagasaki Japan National Research Institute of Far Seas Fisheries Japan Fisheries Research and Education Agency Yokohama Japan Hokkaido National Fisheries Research Institute Japan Fisheries Research and Education Agency Akkeshi Japan Headquaters Japan Fisheries Research and Education Agency Yokohama Japan

To address various fisheries science problems around Japan, the Japan Fisheries Research and Education Agency (FRA) has developed an ocean forecast system by combining an ocean circulation model based on the Regional Ocean Modeling System (ROMS) with three-dimensional variational analysis schemes. This system, which is called FRA-ROMS, is a basic and essential tool for the systematic conduct of fisheries science. The main aim of FRA-ROMS is to realistically simulate mesoscale variations over the Kuroshio-Oyashio region. Here, in situ oceanographic and satellite data were assimilated into FRA-ROMS using a weekly time window. We first examined the reproducibility through comparison with several oceanographic datasets with an Eulerian reference frame. FRA-ROMS was able to reproduce representative features of mesoscale variations such as the position of the Kuroshio path, variability of the Kuroshio Extension, and southward intrusions of the Oyashio. Second, using a Lagrangian reference frame, we estimated position errors between ocean drifters and particles passively transported by simulated currents, because particle tracking is an essential technique used in applications of reanalysis products to fisheries science. Finally, we summarize recent and ongoing fisheries studies that use FRA-ROMS and mention several new developments and enhancements that will be implemented in the near future.

关键词： ROMS 3D-Var Objective Analysis Reanalysis Data Fisheries Science Particle-Tracking Experiment

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早稻田大学国际文学馆（村上春树图书馆）

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城市环境设计 2024年第1期147卷 116-123页

作者：渡边启太渡部悠川澄·小林研二写真事务所

我们将早稻田大学校园内的4号楼改建为新的村上春树图书馆，成为一条穿过原有建筑的“木隧道”。木隧道超越了时间和空间，我们将村上春树小说中连接不同维度的“隧道”转译为建筑空间。我们通过将外墙重新漆成白色涂装和原来的建筑，...

我们将早稻田大学校园内的4号楼改建为新的村上春树图书馆，成为一条穿过原有建筑的“木隧道”。木隧道超越了时间和空间，我们将村上春树小说中连接不同维度的“隧道”转译为建筑空间。我们通过将外墙重新漆成白色涂装和原来的建筑，强调了新建的三维木屏风雨棚。雨棚作为隧道入口的指示，也代表了维度之间的边界。这条木制隧道纵向贯穿了原有的楼板，同时用作书架、剧院和演讲厅。20世纪是混凝土的时代，混凝土具有“坚硬”和“冰冷”的特性。相比之下，对于这个图书馆，我们想象了一条隧道，通过使用细腻柔软的木材来保护我们、培育梦想。

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Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro Nishida Kazuki Kumada kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

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Nature:科学家鉴别出调节机体睡眠的两个关键基因

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现代生物医学进展 2017年第6期17卷 I0002-I0002页

作者： Hiromasa Funato, Chika Miyoshi, Tomoyuki Fujiyama, Takeshi Kanda, Makito Sato, Zhiqiang Wang, Jing Ma, Aya Ikkyu, Miyo Kakizaki, Noriko Hotta-Hirashima, Satomi Kanno, Haruna Komiya, Fuyuki Asano, Takato Honda, Staci J. Kim, Kanako Harano, Hiroki Muramoto, Toshiya Yonezawa, Shinichi Miyazaki, Linzi Connor, Yu Hayashi, Qinghua Liu, Joseph S. Takahashi Masashi Yanagisawa Hiromasa Funato Makito Sato Masashi Yanagisawa Shin Nakane, Jun Tomita Kazuhiko Kume Seiya Mizuno, Fumihiro Sugiyama Satoru Takahashi Vivek Kumar Joseph S. Takahashi Vivek Kumar Ikuo Miura, Tomohiro Suzuki Shigeharu Wakana Atsushi watanabe Manabu Abe kenji Sakimura Yu Hayashi Qinghua Liu Joseph S. Takahashi Masashi Yanagisawa Masashi Yanagisawa International Institute for Integrative Sleep Medicine (WPI-IIIS) University of Tsukuba Tsukuba Ibaraki 305-8575 Japan Department of Anatomy Faculty of Medicine Toho University Ota-ku Tokyo 143-8540 Japan Department of Molecular Genetics University of Texas Southwestern Medical Center Dallas Texas 75390 USA Department of Neuropharmacology Graduate School of Pharmaceutical Sciences Nagoya City University Nagoya Aichi 467-8603 Japan Laboratory Animal Resource Center University of Tsukuba Tsukuba Ibaraki 305-8575 Japan Department of Neuroscience University of Texas Southwestern Medical Center Dallas Texas 75390 USA The Jackson Laboratory Bar Harbor Maine 04609 USA Technology and Development Team for Mouse Phenotype Analysis RIKEN Bioresource Center Tsukuba Ibaraki 305-0074 Japan Laboratory of Research Advancement National Center for Geriatrics and Gerontology Obu Aichi 474-8511 Japan Department of Cellular Neurobiology Brain Research Institute Niigata University Niigata 951-8585 Japan PRESTO Japan Science and Technology Agency Kawaguchi Saitama 332-0012 Japan Department of Biochemistry University of Texas Southwestern Medical Center Dallas Texas 75390 USA Howard Hughes Medical Institute University of Texas Southwestern Medical Center Dallas Texas 75390 USA Life Science Center Tsukuba Advanced Research Alliance University of Tsukuba Tsukuba Ibaraki 305-8575 Japan

近日，刊登在国际杂志Nature上的一项研究报告中，来自西南医学中心等机构的研究人员通过研究鉴别出了两个关键的核心基因，这两个基因能够帮助调节机体深度睡眠和做梦的水平，相关研究或为阐明相关的基因控制睡眠的网络提供新的线索。... 详细信息

近日，刊登在国际杂志Nature上的一项研究报告中，来自西南医学中心等机构的研究人员通过研究鉴别出了两个关键的核心基因，这两个基因能够帮助调节机体深度睡眠和做梦的水平，相关研究或为阐明相关的基因控制睡眠的网络提供新的线索。此前研究者通过对小鼠进行研究发现了能够控制机体快速眼动睡眠的基因，同时该基因还能够诱导深度睡眠。而第二个基因能够控制机体对快速眼动睡眠的需求量，相关研究为科学家们提供了一个关键的切入点来帮助解释睡眠工作的机制，同时研究者还鉴别出了治疗睡眠障碍的潜在靶点。

关键词：睡眠障碍核心基因科学家机体鉴别基因控制研究人员需求量

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