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Granulometric and Mineralogical Characterization of the Sands of the Middle Course of the Kasai River (Territory of Ilebo, Province of Kasai/DR Congo)

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Journal of Geoscience and Environment Protection 2024年第7期12卷 50-71页

作者： Lowny Trésor Madienga Kitshabi Ivon Ndala Tshiwisa Modeste Kisangala Muke Thomas kanika Mamena Dominique Wetshondo Osomba Emmanuel Cibambula Musau Adalbert-Jules Makutu Ma Ngwayaya Department of Petroleum Exploration and Production Faculty of Oil Gas and Renewable Energies University of Kinshasa Kinshasa Democratic Republic of the Congo Department of Geosciences Faculty of Sciences and Technologies University of Kinshasa Kinshasa Democratic Republic of the Congo

The sand bars, in perpetual transformation, observable in the middle course of the Kasai river on the section between the city of Ilebo (pk605) to the confluence of the Loange river (pk525), pose enormous navigability problems. This may be dependent on hydrosedimentological characteristics of the Kasai River. This abundance of sand thus conditions the morphology of the middle course of the Kasai River in the section under our study. It therefore constitutes sedimentary navigation obstacles. The objective of this study is the granulometric and mineralogical characterization of the bar sands of the Kasai River in this study section. Particle size analyzes reveal these are moderately well classified to well classified unimodal sands (Classification coefficient between 1.29 to 1.742) largely presenting grain size symmetry and rarely fine asymmetry (Asymmetry coefficient—Skewness between −0.197 to 0.069) with mesorkurtic and rarely leptokurtic and platykurtic acuity (Angulosity coefficient—Kurtosis between 0.814 to 1.323). All these parameters evolve in sawtooth patterns from upstream to downstream. And then, an automated mineralogical analysis of the sands of the Kasaï River using a Qemscan FEG Quanta 650 made it possible to determine a very varied mineralogical procession with a sawtooth evolution. It is largely dominated by quartz (between 93.73% and 99.07%), followed by calcite (0.01% - 2.66%), iron oxides (0.01% - 1.88%), orthoclase (0.04% - 0.99%), plagioclase (0.01% - 0.75%) and Kaolinite (0.18% - 0.71%). Finally, this mineralogical procession is characterized by a group of minerals which do not reach the threshold of 0.55% such as: illite, apatite, ilmenite, muscovite, chlorite, biotite, montmorillonite, rutile, pyrophyllite, siderite, zircon and dolomite. The evolution of the mineralogical procession of the sands of the bars is not as clear as in the case of particle size parameters.

关键词： Characterization Granulometric Mineralogical Sands Middle Course Kasai River

A Review on Pharmacological and Analytical Aspects of Naringenin

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Chinese Journal of Integrative Medicine 2018年第7期24卷 551-560页

作者： kanika Patel Gireesh Kumar Singh Dinesh Kumar Patel G.L.A Institute of Pharmaceutical Research MathuraIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi-221005India

Flavonoids are a widely distributed group of phytochemicals having benzo-pyrone nucleus, and more than 4,000 different flavonoids have been described and categorized into flavonols, flavones, flavanones, isoflavones, catechins and anthocyanidins. Flavonoids occurs naturally in fruits, vegetables, nuts, and beverages such as coffee, tea, and red wine, as well as in medical herbs. Flavonoids are responsible for the different colors of plant parts and are important constituents of the human diet. Flavanoids have different pharmacological activities, such as antioxidant, anti-allergic, antibacterial, anti-inflammatory, antimutagenic and anticancer activity. Naringenin belongs to the flavanones and is mainly found in fruits（grapefruit and oranges） and vegetables. Pharmacologically, it has anticancer, antimutagenic, anti-inflammatory, antioxidant, antiproliferative and antiatherogenic activities. Naringenin is used for the treatments of osteoporosis, cancer and cardiovascular diseases, and showed lipid-lowering and insulin-like properties. In the present review, detailed pharmacological and analytical aspects of naringenin have been presented, which revealed the impressive pharmacological profile and the possible usefulness in the treatment of different types of diseases in the future. The information provided in this communication will act as an important source for development of effective medicines for the treatment of various disorders.

关键词： analytical techniques flavonoids naringenin pharmacological activity phytoconstituents

A Review on Pharmacological and Analytical Aspects of Diosmetin:A Concise Report

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Chinese Journal of Integrative Medicine 2013年第10期19卷 792-800页

作者： kanika Patel Manoj Gadewar Vijay Tahilyani Dinesh Kumar Patel GLA Institute of Pharmaceutical Research Mathura(281406)India SKIPS Warangal-Andhra Pradesh(506015)India Sonekar College of Pharmacy KoradiNagpur(440001)India Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi(221005)India

Plants have been used as a source for food material and natural remedies for the treatment of vast range of diseases. Nature provides us remedies for the treatment of various types of disorders ranging from simpte aitments to complicated diseases. Plants are known to possess different pharmacological activities due to the presence of various phytoconstituents, Flavonoids are one of the main active phytoconstituents found in fruits, vegetables, wines, tea and cocoa. Flavonoids exhibit various pharmacological activities such as antioxidant, anti-inflammatory, anti-allergic, antibacterial, oestrogenic, cytotoxic antitumoural, hepatoprotective, antithrombotic and antiviral activity. Diosmetin （3＇, 5, 7-trihydroxy-4＇-methoxyflavone）, the aglycone part of the flavonoid glycosides diosmin occurs naturally in citrus fruit. Although it is found in herbal medicines and plays an important role in the treatment of various ailments, only limited scientific researches have been conducted. The aim of this review is to collect all available scientific literature published on diosmetin and combine it into this paper. This review contains an overview of pharmacological activities, isolation techniques and analytical techniques for diosmetin. Thus, valuable information provided in the present review will help researchers in developing alternative methods for the treatment of diseases from diosmetin.

关键词： analytical techniques diosmetin flavonoid pharmacological activity phytoconstituents

Bacterial extracellular vesicle applications in cancer immunotherapy

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Bioactive Materials 2023年第4期22卷 551-566页

作者： kanika Suri Anisha D’Souza Di Huang Aashray Bhavsar Mansoor Amiji Department of Bioengineering College of EngineeringNortheastern UniversityBostonMA02115USA Department of Pharmaceutical Sciences School of PharmacyNortheastern UniversityBostonMA02115USA Massachusetts Eye and Ear Infirmary Harvard Medical SchoolBostonMA20115USA Department of Chemical Engineering College of EngineeringNortheastern UniversityBostonMA02115USA

Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune *** research to identify appropriate immune cells and activate anti-tumor immunity continues to expand,scientists are looking at microbial sources given their inherent ability to elicit an immune *** extracellular vesicles(BEVs)are actively studied to control systemic humoral and cellular immune responses instead of using whole microorganisms or other types of extracellular vesicles(EVs).BEVs also provide the opportunity as versatile drug delivery *** mammalian EVs,BEVs have already made it to the clinic with the meningococcal vaccine(Bexsero®).However,there are still many unanswered questions in the use of BEVs,especially for chronic systemically administered *** this review,we address the opportunities and challenges in the use of BEVs for cancer immunotherapy and provide an outlook towards development of BEV products that can ultimately translate to the clinic.

关键词： Cancer immunotherapy Bacterial extracellular vesicles Membrane vesicles Outer membrane vesicles Mammalian extracellular vesicles

Fusion of Infrared and Visible Images Using Fuzzy Based Siamese Convolutional Network

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Computers, Materials & Continua 2022年第3期70卷 5503-5518页

作者： kanika Bhalla Deepika Koundal Surbhi Bhatia Mohammad Khalid Imam Rahmani Muhammad Tahir Department of Electrical Engineering National Taipei University of TechnologyTaipei10608Taiwan Department Virtualization School of Computer ScienceUniversity of Petroleum&Energy StudiesDehradunIndia College of Computer Science and Information technology King Faisal University36362Saudi Arabia College of Computing and Informatics Saudi Electronic UniversityRiyadh11673Saudi Arabia

Traditional techniques based on image fusion are arduous in integrating complementary or heterogeneous infrared(IR)/visible(VS)*** in various kind of features in these images are vital to preserve in the single fused ***,simultaneous preservation of both the aspects at the same time is a challenging ***,most of the existing methods utilize the manual extraction of features;and manual complicated designing of fusion rules resulted in a blurry artifact in the fused ***,this study has proposed a hybrid algorithm for the integration of multi-features among two heterogeneous ***,fuzzification of two IR/VS images has been done by feeding it to the fuzzy sets to remove the uncertainty present in the background and object of interest of the ***,images have been learned by two parallel branches of the siamese convolutional neural network(CNN)to extract prominent features from the images as well as high-frequency information to produce focus maps containing source image ***,the obtained focused maps which contained the detailed integrated information are directly mapped with the source image via pixelwise strategy to result in fused *** parameters have been used to evaluate the performance of the proposed image fusion by achieving 1.008 for mutual information(MI),0.841 for entropy(EG),0.655 for edge information(EI),0.652 for human perception(HP),and 0.980 for image structural similarity(ISS).Experimental results have shown that the proposed technique has attained the best qualitative and quantitative results using 78 publically available images in comparison to the existing discrete cosine transform(DCT),anisotropic diffusion&karhunen-loeve(ADKL),guided filter(GF),random walk(RW),principal component analysis(PCA),and convolutional neural network(CNN)methods.

关键词： Convolutional neural network fuzzy sets infrared and visible image fusion deep learning

Handling Class Imbalance in Online Transaction Fraud Detection

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Computers, Materials & Continua 2022年第2期70卷 2861-2877页

作者： kanika Jimmy Singla Ali Kashif Bashir Yunyoung Nam Najam UI Hasan Usman Tariq School of Computer Science and Engineering Lovely Professional UniversityPunjabIndia Department of Computing and Mathematics ManchesterMetropolitan UniversityUK&School of Electrical Engineering and Computer ScienceNational University of Science and TechnologyIslamabadPakistan Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea Department of Electrical and Computer Engineering Dhofar UniversitySalalahOman College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAl-Kharj11942Saudi Arabia

With the rise of internet facilities,a greater number of people have started doing online transactions at an exponential rate in recent years as the online transaction system has eliminated the need of going to the bank physically for every ***,the fraud cases have also increased causing the loss of money to the ***,an effective fraud detection system is the need of the hour which can detect fraudulent transactions automatically in ***,the genuine transactions are large in number than the fraudulent transactions which leads to the class imbalance *** this research work,an online transaction fraud detection system using deep learning has been proposed which can handle class imbalance problem by applying algorithm-level methods which modify the learning of the model to focus more on the minority class i.e.,fraud transactions.A novel loss function named Weighted Hard-Reduced Focal Loss(WH-RFL)has been proposed which has achieved maximum fraud detection rate i.e.,True PositiveRate(TPR)at the cost of misclassification of few genuine transactions as high TPR is preferred over a high True Negative Rate(TNR)in fraud detection system and same has been demonstrated using three publicly available imbalanced transactional ***,Thresholding has been applied to optimize the decision threshold using cross-validation to detect maximum number of frauds and it has been demonstrated by the experimental results that the selection of the right thresholding method with deep learning yields better results.

关键词： Class imbalance deep learning fraud detection loss function thresholding

Evaluating Security of Big Data Through Fuzzy Based Decision-Making Technique

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Computer Systems Science & Engineering 2023年第1期44卷 859-872页

作者： Fawaz Alassery Ahmed Alzahrani Asif Irshad Khan kanika Sharma Masood Ahmad Raees Ahmad Khan Department of Computer Science College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif 21944Saudi Arabia Department of Computer Science Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Computer Applications Mangalmay Institute of Engineering&TechnologyGreater Noida201310Uttar PradeshIndia Department of Information Technology Babasaheb Bhimrao Ambedkar UniversityLucknow226025Uttar PradeshIndia

In recent years,it has been observed that the disclosure of information increases the risk of *** restricting the accessibility of information,providing security is ***,there is a demand for time tofill the gap between security and accessibility of *** fact,security tools should be usable for improving the security as well as the accessibility of *** security and accessibility are not directly influenced,some of their factors are indirectly influenced by each *** play an important role in bridging the gap between security and *** this paper,we identify the key attributes of accessibility and security that impact directly and indirectly on each other,such as confidentiality,integrity,availability,and *** significance of every attribute on the basis of obtained weight is important for its effect on security during the big data security life cycle *** calculate the proposed work,researchers utilised the Fuzzy Analytic Hierarchy Process(Fuzzy AHP).Thefindings show that the Fuzzy AHP is a very accurate mechanism for determining the best security solution in a real-time healthcare *** study also looks at the rapidly evolving security technologies in healthcare that could help improve healthcare services and the future prospects in this area.

关键词： Information security big data big data security life cycle fuzzy AHP

A review on pharmacological and analytical aspects of diosgenin:a concise report

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Natural Products and Bioprospecting 2012年第2期2卷 46-52页

作者： kanika PATEL Manoj GADEWAR Vijay TAHILYANI Dinesh Kumar PATEL G.L.A Institute of Pharmaceutical Research MathuraIndia S.K.I.P.S.Warangal A.P.India Sonekar College of Pharmacy KoradiNagpurIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi 221005India

Diosgenin is a steroidal sapogenin found in plants such as Dioscorea nipponoca,Solanum incanum,Solanum xanthocarpum and Trigonella foenum ***,biologically active phytochemicals have been used for the treatment of various types of disorder such as leukemia,inflammation,hypercholesterolemia and *** is also able to prevent bone loss to the same extent as that of *** is a typical initial intermediate for synthesis of steroidal compounds,oral contraceptives and sex ***,Costus and Trigonella are mainly used for the production of *** the basis of literature survey it divulges that diosgenin has very impressive pharmacological profile and could be used as a medicine for the treatment of different types of disorders in the ***,the present work aims to provide collective information in concern with its pharmacological activity and phytoanalytical *** review will be beneficial to researches for the development of an alternative method for the treatment of innumerable diseases from diosgenin.

关键词： analytical techniques cancer diosgenin pharmacological activity plant source seperation techniques

Platelets in Kawasaki disease:Is this only a numbers game or something beyond?

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Genes & Diseases 2020年第1期7卷 62-66页

作者： kanika Arora Sandesh Guleria Ankur Kumar Jindal Amit Rawat Surjit Singh Allergy Immunology Unit Department of PediatricsAdvanced Pediatrics CentrePostgraduate Institute of Medical Education and ResearchChandigarhIndia

Kawasaki disease(KD)is a medium vessel vasculitis with predilection to cause coronary artery *** is now the most common cause of acquired heart disease in developed *** is consistently found in patients with KD,usually in 2nd to 3rd week of *** has occasionally been reported in the acute phase of *** increase or decrease in platelet number in patients with KD was initially considered to be a benign ***,recent literature on platelet biology in KD has suggested that platelets are not only increasing but are rather *** phenomenon has been found to increase the risk of thrombosis in these *** a fall in platelet counts during acute stage of KD has also been found to be associated with increased severity of *** this review,we update on the current best understanding about pathogenic role of platelets in patients with KD.

关键词： Aspirin CD40 ligand Kawasaki disease Platelet derived microparticles Platelets Thrombosis