检索结果-南通市图书馆

体内选择性内皮细胞胰岛素敏感性增强:一种新的促使动脉粥样硬化的信号通路

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中华高血压杂志 2016年第12期24卷 1105-1105页

作者：刘莉叶鹏 Viswambharan H Yuldasheva NY Sengupta A Imrie H Gage MC Haywood NJ Walker AM Skromna A Makova N Galloway SL Shah P Sukumar P porter kE Grant PJ Shah AM Santos CX Li J Beech DJ Wheatcroft S Cubbon RM kearney MT

在内皮中,胰岛素刺激内皮型一氧化氮合酶（endothelial nitric oxide synthase,eNOS）以产生抗动脉粥样硬化信号的自由基——一氧化氮。2型糖尿病患者可利用的一氧化氮减少,导致动脉粥样硬化改变。内皮细胞胰岛素敏感性增加对一氧化氮... 详细信息

在内皮中,胰岛素刺激内皮型一氧化氮合酶（endothelial nitric oxide synthase,eNOS）以产生抗动脉粥样硬化信号的自由基——一氧化氮。2型糖尿病患者可利用的一氧化氮减少,导致动脉粥样硬化改变。内皮细胞胰岛素敏感性增加对一氧化氮合成的影响尚不清楚。为了回答这个问题,该研究使用Tie2启动子增强子构建内皮细胞特异性过表达人类胰岛素受体（endothelial cell-specific over-expression of the human insulin receptor, hlRECO）的小鼠模型。

关键词：内皮细胞信号通路超氧化物启动子酪氨酸磷酸化增强子 dinucleotide 特异性 NADPH nicotinamide

维普期刊数据库

Methods for a blind analysis of isobar data collected by the STAR collaboration

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2021年第5期32卷 43-50页

作者： J.Adam L.Adamczyk J.R.Adams J.k.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi k.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderon de la Barca Sanchez D.Cebra I.Chakaberia P.Chaloupka B.k.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanad M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson k.Gopal X.Gou D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He Y.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.Ji J.Jia k.Jiang S.Jowzaee X.Ju E.G.Judd S.kabana M.L.kabir S.kagamaster D.kalinkin k.kang D.kapukchyan k.kauder H.W.ke D.keane A.kechechyan M.kelsey Y.V.khyzhniak D.P.kikoła C.kim B.kimelman D.kincses T.A.kinghorn I.kisel A.kiselev M.kocan L.kochenda L.k.kosarzewski L.kramarik P.kravtsov k.krueger N.kulathunga Mudiyanselage L.kumar S.kumar R.kunnawalkam Elayavalli J.H.kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.lebedev R.lednicky J.H.lee Y.H.leung C.Li C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Md.Nasim k.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonak Christian University AbileneTX 796992 AGH University of Science and Technology FPACSCracow 30-059Poland Alikhanov Institute for Theoretical and Experimental Physics NRC"kurchatov Institute" MoscowRussia 117218 Argonne National Laboratory ArgonneIL 60439 American University of Cairo New CairoNew Cairo 11835Egypt Brookhaven National Laboratory UptonNY 11973 University of California BerkeleyCA 94720 University of California DavisCA 95616 University of California Los AngelesCA 90095 University of California RiversideCA 92521 Central China Normal University Wuhan 430079 University of Illinois at Chicago ChicagoIL 60607 Creighton University OmahaNE 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universitat Darmstadt Darmstadt 64289Germany ELTE Eotvos Lorand University Budapest 1117Hungary Frankfurt Institute for Advanced Studies FIAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg 69120 HeidelbergGermany University of Houston HoustonTX 77204 Huzhou University Huzhou 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIN 47408 Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000 University of Jammu Jammu 180001India Joint Institute for Nuclear Research DubnaRussia 141980 kent State University KentOH 44242 University of kentucky LexingtonKY 40506-0055 Lawrence Berk.ley National Laboratory BerkeleyCA 94720 lehigh University BethlehemPA 18015 Max-Planck-Institut fur Physik 80805 MunichGermany Michigan State University East LansingMI 48824 National Research Nuclear University MEPhI MoscowRussia 115409 National Institute of Science Education and Research HBNIJatni 752050India National Cheng kung University Tainan 70101 Nuclear Physics Institute of the CAS Rez 25068Czech Republic Ohio State University

In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of *** isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)*** order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis *** are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run *** tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking *** this sample,species-specific information is disguised,but individual output files contain data from a single isobar *** run-by-run corrections and code alteration subsequent to these corrections are allowed at this *** these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind *** a check of the feasibility of the blind analysis procedure,analysts completed a"mock data challenge,"analyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in *** Au+Au data were prepared in the same manner intended for the isobar blind *** details of the blind analysis procedure and results from the mock data challenge are presented.

关键词： Blind analysis Chiral magnetic effect Heavy-ion collisions

维普期刊数据库

Measurement of away-side broadening with self-subtraction of flow in Au+Au collisions at √sNN=200 GeV

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2020年第10期44卷 59-67页

作者： L.Adamczyk J.R.Adams J.k.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi k.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderón de la Barca Sánchez D.Cebra I.Chakaberia P.Chaloupka B.k.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanád M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson k.Gopal D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.JI J.Jia k.Jiang S.Jowzaee X.Ju E.G.Judd S.kabana M.L.kabir S.kagamaster D.kalinkin k.kang D.kapukchyan k.kauder H.W.ke D.keane A.kechechyan M.kelsey Y.V.khyzhniak D.P.kikoła C.kim B.kimelman D.kincses T.A.kinghorn I.kisel A.kiselev M.kocan L.kochenda L.k.kosarzewski L.kramarik P.kravtsov k.krueger N.kulathunga Mudiyanselage L.kumar S.kumar R.kunnawalkam Elayavalli J.H.kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.lebedev R.lednicky J.H.lee Y.H.leung C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Nasim Md k.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa Abilene Christian University AbileneTexas 79699 AGH University of Science and Technology FPACSCracow 30-059Poland Alikhanov Institute for Theoretical and Experimental Physics NRC"kurchatov Institute" Moscow 117218Russia Argonne National Laboratory ArgonneIllinois 60439 American University of Cairo New Cairo 11835New CairoEgypt Brookhaven National Laboratory UptonNew York 11973 University of California BerkeleyCalifornia 94720 University of California DavisCalifornia 95616 University of California Los AngelesCalifornia 90095 University of California RiversideCalifornia 92521 Central China Normal University WuhanHubei 430079 University of Illinois at Chicago ChicagoIllinois 60607 Creighton University OmahaNebraska 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universität Darmstadt Darmstadt 64289Germany ELTE Eötvös Loránd University BudapestHungary H-1117 Frankfurt Institute for Advanced Studies FIAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg Heidelberg 69120Germany University of Houston HoustonTexas 77204 Huzhou University HuzhouZhejiang 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIndiana 47408 Institute of Modern Physics Chinese Academy of SciencesLanzhouGansu 730000 University of Jammu Jammu 180001India Joint Institute for Nuclear Research Dubna 141980Russia kent State University KentOhio 44242 University of kentucky LexingtonKentucky 40506-0055 Lawrence Berk.ley National Laboratory BerkeleyCalifornia 94720 lehigh University BethlehemPennsylvania 18015 Max-Planck-Institut für Physik Munich 80805Germany Michigan State University East LansingMichigan 48824 National Research Nuclear University MEPhI Moscow 115409Russia National Institute of Science Education and Research HBNIJatni 752050Indi

High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion *** of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic *** report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR *** correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5

关键词： di-hadron correlations jet heavy-ion

维普期刊数据库

低失真读出分段平面回波成像在头颈部区域的临床应用:初步经验

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2015年第1期 95-95页

作者： S.koyasu M.Iima S.Umeoka N.Morisawa D.A.porter J.Ito Department of Diagnostic Imaging and Nuclear Medicine Graduate School of MedicineKyoto University

目的与单次激发平面回波成像扩散加权成像(SS-EPI DWI)对比,评估在头颈部区域应用分段读取平面回波成像(RS-EPI)DWI能否减少影像失真。方法采用16通道

关键词：平面回波成像加权成像 DWI 头颈部 EPI

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

用算法消灭入侵灯笼蝇

环球科学 2021年第5期 19-19页

作者：克莱尔·玛丽·波特林清(翻译) 不详

有一种体长3厘米、形似蛾子的飞虱叫做斑点灯笼蝇(spotted lantemfly),来自东南亚部分地区。自2014年首次在宾夕法尼亚州伯克斯县(Berks County)发现它们以来,这种灯笼蝇给美国东海岸的木材、果树和酿酒业造成了严重的破坏。更糟糕的是... 详细信息

有一种体长3厘米、形似蛾子的飞虱叫做斑点灯笼蝇(spotted lantemfly),来自东南亚部分地区。自2014年首次在宾夕法尼亚州伯克斯县(Berks County)发现它们以来,这种灯笼蝇给美国东海岸的木材、果树和酿酒业造成了严重的破坏。更糟糕的是,它可能已经席卷宾夕法尼亚州下属的26个县及新泽西州、特拉华州、马里兰州和弗吉尼亚州的部分地区。

关键词：美国东海岸弗吉尼亚州宾夕法尼亚州特拉华州马里兰州灯笼酿酒业伯克斯

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

腹腔镜辅助光动力系统的设计和临床应用探讨

中国激光医学杂志 2010年第6期19卷 380-380页

作者：苗雄鹰杨竹林熊力文宇刘威陈勇曹汉韶 William porter Dr Alexander Matt Murphy Terry Timms 中南大学湘雅二医院普外腔镜中心广州曹氏开发集团

光线无法穿透腹壁,使腹内组织和脏器处于黑暗状态,因此无法行光动力疗法治疗。笔者设计的腔镜外科辅助光动力系统,结合外科技术和光动力学原理,在手术切除大部分肿瘤的同时,照射腹腔内残余瘤。该方

关键词：术中

心肌型脂肪酸结合蛋白是冠脉搭桥术后死亡和心室功能不全的独立预测因素

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

麻醉与镇痛 2012年第1期8卷 40-50页

作者： Jochen D. Muehlschlegel, MD Tjorvi E. Perry, MD kuang-Yu Liu, PhD Amanda A. Fox, MD Charles D. Collard, MD Stanton k. Shernan, MD Simon C. Body, MD 刘媛媛（译）彭丽桦（译） Department of Anesthesiology Perioperative and Pain Medicine Brigham and Women＇s HospitalBoston Massachusetts Division of Cardiovascular Anesthesia Baylor College of MedicineTexas Heart Institute Saint Luke＇s Episcopal Hospital Houston Texas

背景心肌型脂肪酸结合蛋白（heart-typefattyacidbindingprotein，hFABP）作为心肌脂肪酸的转运体，在心肌损害的早期即可释放入血。我们假设hFABP可用于早期预测冠脉搭桥术围术期心肌损害的发生，其敏感性更优于传统的心脏生物标志物... 详细信息

背景心肌型脂肪酸结合蛋白（heart-typefattyacidbindingprotein，hFABP）作为心肌脂肪酸的转运体，在心肌损害的早期即可释放入血。我们假设hFABP可用于早期预测冠脉搭桥术围术期心肌损害的发生，其敏感性更优于传统的心脏生物标志物。方法本研究为前瞻性队列研究，共纳入两家医疗机构体外循环下行冠脉搭桥术（coronaryarterybypassgraft，CABG）的患者1298例。在围术期的7个不同时点分别检测了血浆中的4种心肌损害标志物：hFABP、肌钙蛋白Ⅰ、心肌型肌酸激酶同工酶MB（creatingkinaseMB，Ck-MB）以及肌红蛋白。采用Cox比例风险模型，评价围术期心肌标志物水平与心室功能不全、住院时间以及术后5年死亡率（时间中位数3．3年）的相关性。患者住院期间心室功能不全定义：需要新增加2种或以上的强心药物治疗、安置新的主动脉内球囊反搏、需要在术中停止体外循环时或者术后在监护室中使用心室辅助装置。结果hFABP对于心脏手术患者死亡率的阳性和阴性预测值分别为13％（95％可信区间，9％。19％）和95％（95％可信区间，94％-96％），高于肌钙蛋白Ⅰ和***。将其作为临床预测因素进行校正后，术后第1天hFABP水平及其峰值水平均是冠脉搭桥术后心室功能不全（P〈0．0001）、住院时间延长（P〈0．05）和5年死亡率增加（P〈0．0001）的独立预测因素。另外，术后第1天hFABP水平及其峰值水平在预测患者死亡率时显著优于研究纳入的其他生物标志物。在重复测量方差分析中，hFABP与其他拟合模型相比能更好的预测患者住院时间。术后第2天hFABP高于停止体外循环时水平的患者，其死亡率显著高于术后第2天hFABP低于停止体外循环时水平的患者（风险比，10．9；95％可信区间，5．0-23．7；P=7．2×10^-10）。出现延迟性hFABP峰值的120例患者（占患者总人数的10％）的死亡率为18．3％，未出现延迟性hFABP峰值患者的死亡率仅为4．7％。而是否出现肌钙蛋白Ⅰ和Ck-MB的延迟峰值对患者死亡率无显著影响。结论与冠脉搭桥术后传统的心肌损伤标志物相比较，hFABP在CABG术后早期可达峰值，是一种更具优势的患者术后死亡和心室功能不全的独立预测因素。

关键词：心肌型脂肪酸结合蛋白独立预测因素心室功能不全冠脉搭桥术术后死亡 Cox比例风险模型心肌损害标志物心肌型肌酸激酶同工酶