检索结果-南通市图书馆

Advances in Atmospheric Sciences 2020年第6期37卷 634-651页

作者： P.P.BABURAJ S.ABHILASH k.mohankumar A.k.SAHAI Department of Atmospheric Sciences Cochin University of Science and TechnologyCochin 682016India Regional Meteorological Center India Meteorological DepartmentChennai 600006India Advanced Center for Atmospheric Radar Research Cochin University of Science and TechnologyCochin 682022India Indian Institute of Tropical Meteorology Dr.Homi Bhabha RoadPashanPune 411008India

In this paper we examine the epochal changes in the frequency of cyclones over the North Indian Ocean during the pre-onset and onset phases of the *** consider three epochs;namely,the early(1955-74),middle(1975-94)and recent(1995-2014)*** is found that the number of cyclones in the Bay of Bengal(BOB)decreases throughout the three *** the Arabian Sea(ARB),however,there is a decrease in the early epoch,before then reaching a minimum in the middle epoch followed by an increase in the recent epoch,thus exhibiting epochal *** and thermodynamic parameters along with Genesis Potential Index(GPI)are examined to understand the frequency variation in cyclogenesis over the ARB and *** the ARB,thermodynamic factors such as mid-level moisture,surface latent heat flux and sensible heat flux,and dynamic parameters such as lower-level convergence and upper-level divergence,are favorable during the early and recent epochs but unfavorable during the middle epoch,and these results are found to be consistent with the observed epochal variability in the frequency of ***,all these influential parameters are found to have decreased over the BOB during the entire 60-year period.

关键词： epoch Indian moisture

EXISTENCE, UNIQUENESS AND STABILITY OF RANDOM IMPULSIVE FRACTIONAL DIFFERENTIAL EQUATIONS

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Scientia 2016年第2期36卷 428-442页

作者： A.Vinodkumar k.Malar M.Gowrisankar P.mohankumar Department of Mathematics Amrita School of EngineerringAmrita Vishwa Vidyapeetham University Department of Mathematics Erode Arts and Science College Department of Mathematics Annapoorana Engineering College Department of Mathematics A.C.T College of Engineering and Technology

In this article, we study the existence, uniqueness, stability through continuous dependence on initial conditions and Hyers-Ulam-Rassias stability results for random impulsive fractional differential systems by relax... 详细信息

关键词： Fractional differential systems random impulses stability Hyers-Ulam stability Hyers-Ulam-Rassias stability

STABILITY RESULTS OF RANDOM IMPULSIVE SEMILINEAR DIFFERENTIAL EQUATIONS

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Scientia 2014年第4期34卷 1055-1071页

作者： M.GOWRISANkAR P.mohankumar A.VINODkUMAR Department of Mathematics Annapoorana Engineering College Salem- 636308Tamil NaduIndia Department of Mathematics Arupadai Veedu Institute of Technology Chennai- 636104 Department of Mathematics PSG College of Technology Coimbatore- 641004Tamil NaduIndia

In this paper, we study the existence, uniqueness, continuous dependence, Ulam stabilities and exponential stability of random impulsive semilineax differential equations under sufficient condition. The results are obtained by using the contraction mapping principle. Finally an example is given to illustrate the applications of the abstract results.

关键词： semilinear differential equations random impulses stability, Hyers-Ulam stability Hyers-Ulam-Rassias stability exponential stability contraction principle

Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHAMMAD M.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

关键词：

Effects of P301L-TAU on post-translational modifications of microtubules in human iPSC-derived cortical neurons and TAU transgenic mice

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2348-2360页

作者： Mohamed Aghyad Al kabbani Christoph köhler Hans Zempel Institute of Human Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) University of CologneCologneGermany Center Anatomy Department ⅡMedical FacultyUniversity of CologneCologneGermany

TAU is a microtubule-associated protein that promotes microtubule assembly and stability in the *** is missorted and aggregated in an array of diseases known as *** are essential for neuronal function and regulated via a complex set of post-translational modifications,changes of which affect microtubule stability and dynamics,microtubule interaction with other proteins and cellular structures,and mediate recruitment of microtubule-severing *** impairment of microtubule dynamics causes neuronal dysfunction,we hypothesize cognitive impairment in human disease to be impacted by impairment of microtubule *** therefore aimed to study the effects of a disease-causing mutation of TAU(P301L)on the levels and localization of microtubule post-translational modifications indicative of microtubule stability and dynamics,to assess whether P301L-TAU causes stability-changing modifications to *** investigate TAU localization,phosphorylation,and effects on tubulin post-translational modifications,we expressed wild-type or P301L-TAU in human MAPT-kO induced pluripotent stem cell-derived neurons(i Neurons)and studied TAU in neurons in the hippocampus of mice transgenic for human P301L-TAU(p R5 mice).Human neurons expressing the longest TAU isoform(2N4R)with the P301L mutation showed increased TAU phosphorylation at the AT8,but not the p-Ser-262 epitope,and increased polyglutamylation and acetylation of microtubules compared with endogenous TAU-expressing neurons.P301L-TAU showed pronounced somatodendritic presence,but also successful axonal enrichment and a similar axodendritic distribution comparable to exogenously expressed 2N4R-wildtype-TAU.P301L-TAU-expressing hippocampal neurons in transgenic mice showed prominent missorting and tauopathy-typical AT8-phosphorylation of TAU and increased polyglutamylation,but reduced acetylation,of microtubules compared with non-transgenic *** sum,P301L-TAU results in changes in micr

关键词： human induced pluripotent stem cell microtubules P301L pR5 mice TAU tauopathy tubulin code

Effect of underlap and gate length on device performance of an AlInN/GaN underlap MOSFET

在线全文

学校读者我要写书评

暂无评论

Journal of Semiconductors 2012年第12期33卷 16-22页

作者： Hemant Pardeshi Sudhansu kumar Pati Godwin Raj N mohankumar Chandan kumar Sarkar Nano Device Simulation Laboratory Electronics and Telecommunication Engineering DepartmentJadavpur University SkP Engineering College

We investigate the performance of an 18 nm gate length AIInN/GaN heterostructure underlap double gate MOSFET, using 2D Sentaurus TCAD simulation. The device uses lattice-matched wideband Al0.83In0.17N and narrowband GaN layers, along with high-k Al2O3 as the gate dielectric. The device has an ultrathin body and is designed according to the ITRS specifications. The simulation is done using the hydrodynamic model and interface traps are also considered. Due to the large two-dimensional electron gas （2DEG） density and high velocity, the maximal drain current density achieved is very high. Extensive device simulation of the major device performance metrics such as drain induced barrier lowering （DIBL）, subthreshold slope （SS）, delay, threshold voltage （Vt）, Ion/Ioff ratio and energy delay product have been done for a wide range of gate and underlap lengths. Encouraging results for delay, Ion, DIBL and energy delay product are obtained. The results indicate that there is a need to optimize theIoff and SS values for specific logic design. The proposed AlInN/GaN heterostructure underlap DG MOSFET shows excellent promise as one of the candidates to substitute currently used MOSFETs for future high speed applications.

关键词： MOS-HEMT underlap heterostructure ultrathin body interface traps effective mass

A 2DEG charge density based drain current model for various Al and In molefraction mobility dependent nano-scale AlInGaN/AlN/GaN HEMT devices

在线全文

学校读者我要写书评

暂无评论

Journal of Semiconductors 2013年第4期34卷 24-29页

作者： Godwin Raj Hemant Pardeshi Sudhansu kumar Pati N mohankumar Chandan kumar Sarkar Nano Device Simulation Laboratory Electronics and Telecommunication Engineering DepartmentJadavpur UniversityKolkata-700 032India SkP Engineering College TiruvannamalaiTamilnadu-606 611India

We present a two-dimensional electron gas （2DEG） charge-control mobility variation based drain cur- rent model for sheet carrier density in the channel. The model was developed for the AIInGaN/A1N/GaN high- electron-mobility transistor. The sheet carrier density model used here accounts for the independence between the Fermi levels Ef and ns along with mobility for various AI and In molefractions. This physics based ns model fully depends upon the variation of El, u0, the first subband E0, the second subband El, and as. We present a physics based analytical drain current model using ns with the minimum set of parameters. The analytical resuks obtained are compared with the experimental results for four samples with various molefraction and barrier thickness. A good agreement between the results is obtained, thus validating the model.

关键词： 2DEG Fermi level AlInGaN

Performance evaluation of cone penetrometer device for measuring the subsoil compaction in mulched plots

在线全文

学校读者我要写书评

暂无评论

International Journal of Agricultural and Biological Engineering 2013年第3期6卷 19-27页

作者： R.Thiyagarajan G.C.Jayashree A.P.mohankumar P.Vijayakumary Agricultural Engineering College and Research Institute Tamil Nadu Agricultural UniversityKumulur 621712Tamil NaduIndia Department of Agricultural Engineering University of Agricultural SciencesBangalore-560065KarnatakaIndia Agricultural Engineering College and Research Institute Tamil Nadu Agricultural UniversityCoimbatore 641003Tamil NaduIndia

Soil exhibits layers of extreme compaction from both natural causes and wheel *** compaction layers impede root growth,thereby reducing the plants capacity to obtain water during *** tillage is a remedy for adverse soil compaction that results in improved conditions for crop *** disturbance of subsoil increases water holding capacity and reduces impedance to root *** mulching is a technique that can be used to partially alleviate soil compaction within the critical root zones of deep rooted crops.A study was conducted by placing raw and composted coir pith using a two row subsoil coir pith mulching machine in three different soil depths(250,350,and 450 mm)at the three application rates of 15 t/ha,20 t/ha,and 25 t/ha and the effect of soil strength was *** experiment was conducted for a rainfed cotton *** soil strength profile was recorded in all the *** cone penetrometer resistance was measured for each increment of 10 mm and recorded manually from a digital force indicator during maturity stages of crop in all the treatment *** cone penetrometer resistance was measured directly on the row and the cone index was *** placement of mulch reduced the soil strength as compared to shallow *** lower soil strength(0.5 kPa to 0.8 kPa)in the loosened and mulched zone provided an impedance free zone for the root to *** rapid increase in cone index values at depths immediately below the respective depth of placement(250,350 and 450 mm)of raw and composted coir pith mulch indicated that the existence of undisturbed soil profile below the mulched zone which could be potential limiting factor for root development.

关键词： soil strength raw coir pith composted coir pith cone penetrometer cone index subsoil compaction

Flicker and thermal noise in an n-channel underlap DG FinFET in a weak inversion region

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2013年第2期34卷 31-36页

作者： Sudhansu kumar Pati Hemant Pardeshi Godwin Raj N mohankumar Chandan kumar Sarkar Nano Device Simulation Laboratory Electronics and Telecommunication Engineering DepartmentJadavpur University SkP College of Engineering TiruvannamalaiTamilnadu-606 611India

We propose an analytical model for drain current and inversion charge in the subthreshold region for an underlap DG FinFET by using the minimum channel potential method, i.e., the virtual source. The flicker and thermal noise spectral density models are also developed using these charge and current models expression. The model is validated with already published experimental results of flicker noise for DG FinFETs. For an ultrathin body, the degradation of effective mobility and variation of the scattering parameter are considered. The effect of device parameters like gate length Lg and underlap length Lun on both flicker and thermal noise spectral densities are also analyzed. Increasing Lg and Lun, increases the effective gate length, which reduces drain current, resulting in decreased flicker and thermal noise density. A decrease of flicker noise is observed for an increase of frequency, which indicates that the device can be used for wide range of frequency applications.

关键词： flicker noise thermal noise ultrathin body virtual source underlap DG FinFET

Transcription factors specificity protein and nuclear receptor 4A1 in pancreatic cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2021年第38期27卷 6387-6398页

作者： Stephen Safe Rupesh Shrestha kumaravel mohankumar Marcell Howard Erik Hedrick Maen Abdelrahim Department of Veterinary Physiology and Pharmacology Texas A&M UniversityCollege StationTX 77845United States Department of Biochemistry and Biophysics Texas A&M UniversityCollege StationTX 77845United States Cancer Institute Cleveland ClinicClevelandOH 44195United States Department of Medical Oncology Houston Methodist Hospital Cancer CenterHoustonTX 77030United States

Specificity protein(Sp)transcription factors(TFs)Sp1,Sp3 and Sp4,and the orphan nuclear receptor 4A1(NR4A1)are highly expressed in pancreatic tumors and Sp1 is a negative prognostic factor for pancreatic cancer patient *** of knockdown and overexpression of Sp1,Sp3 and Sp4 in pancreatic and other cancer lines show that these TFs are individually pro-oncogenic factors and loss of one Sp TF is not compensated by other ***4A1 is also a prooncogenic factor and both NR4A1 and Sp TFs exhibit similar functions in pancreatic cancer cells and regulate cell growth,survival,migration and *** is also evidence that Sp TFs and NR4A1 regulate some of the same genes including survivin,epidermal growth factor receptor,PAX3-FOXO1,α5-andα6-integrins,β1-,β3-andβ4-integrins;this is due to NR4A1 acting as a cofactor and mediating NR4A1/Sp1/4-regulated gene expression through GC-rich gene promoter *** studies show that drugs targeting Sp downregulation or NR4A1 antagonists are highly effective inhibitors of Sp/NR4A1-regulated pathways and genes in pancreatic and other cancer cells,and the triterpenoid celastrol is a novel dual-acting agent that targets both Sp TFs and NR4A1.

关键词： Specificity protein Nuclear receptor 4A1 Pancreatic cancer Transcription factors Ligand inhibitors Nuclear receptor 4A antagonists