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C-phycocyanin shows neuroprotective effect against rotenone-induced Parkinson’s disease in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 279-287页

作者： Hritik Rathod Ritu M.soni Jigna s.shah Department of Pharmacology Institute of Pharmacy Nirma UniversityAhmedabadGujaratIndia

Objective:To investigate the neuroprotective effect of C-phycocyanin in a mouse model of rotenone-induced Parkinson’s ***:C-phycocyanin(50 mg/kg,i.p.,daily)was administered to rotenone(30 mg/kg,p.o.,daily)treated mice for 28 *** studies(Y-maze,rotarod,round beam walk,and wire-hang tests)were carried out to assess neurobehavioral *** and malondialdehyde were determined in both serum and striatal *** proteins(AkT,AMPk,NF-κB,BDNF,and alpha-synuclein)in the striatum were estimated using *** analyses(hematoxylin and eosin stainning as well as Nissl staining)were carried out to assess structural abnormalities in the ***:C-phycocyanin significantly increased BDNF levels and decreased alpha-synuclein *** also slightly upregulated AMPk and AkT levels without significant difference compared with the rotenone ***,rotenone-induced elevated oxidative stress and structural abnormalities in the striatum were markedly mitigated by ***:C-phycocyanin might have potential neuroprotective effects against Parkinson’s *** studies are warranted to verify its efficacy and to understand the molecular mechanisms behind the neuroprotective effects of C-phycocyanin in Parkinson’s disease.

关键词： Parkinson’s disease C-phycocyanin Alphasynuclein BDNF Oxidative stress Rotenone

Navigating the future of malaria control:Insights from India's pioneering malaria slide bank

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Asian Pacific Journal of Tropical Medicine 2024年第3期17卷 139-140页

作者： sheikh Mohd saleem shah sumaya Jan Public Health Expert Health SectionInternational Non-Government OrganisationNew DelhiIndia Department of Anatomy Government.Medical CollegeSrinagarIndia

We applaud the authors for their illuminating perspective on India's malaria slide bank(MsB),featured in the recent publication in your esteemed journal[1].The article provides a comprehensive overview of the establishment,challenges,and future potential of MsBs,offering valuable insights into the complexities and opportunities inherent in this critical asset for India's malaria elimination program.

关键词： malaria journal offering

Mathematical modeling and simulations of stress mitigation by coating polycrystalline particles in lithium-ion batteries

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 947-962页

作者： N.IQBAL J.CHOI s.F.shah C.LEE s.LEE Department of Mechanical Roboticsand Energy EngineeringDongguk University-SeoulSeoul 04620Republic of Korea

A chemo-mechanical model is developed to investigate the effects on the stress development of the coating of polycrystalline Ni-rich LiNixMnyCo_(z)O_(2)(x≥0.8)(NMC)particles with poly(3,4-ethylenedioxythiophene)(PEDOT).The simulation results show that the coating of primary NMC particles significantly reduces the stress generation by efficiently accommodating the volume change associated with the lithium diffusion,and the coating layer plays roles both as a cushion against the volume change and a channel for the lithium transport,promoting the lithium distribution across the secondary particles more ***,the lower stiffness,higher ionic conductivity,and larger thickness of the coating layer improve the stress *** paper provides a mathematical framework for calculating the chemo-mechanical responses of anisotropic electrode materials and fundamental insights into how the coating of NMC active particles mitigates stress levels.

关键词： lithium-ion battery(LIB) polycrystalline particle coating finite element simulation Ni-rich LiNixMnyCo_(z)O_(2)(x>0.8)(NMC)

On the analytical soliton approximations to fractional forced korteweg-de Vries equation arising in fluids and plasmas using two novel techniques

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Communications in Theoretical Physics 2024年第8期76卷 1-10页

作者： Weaam Alhejaili Emad A Az-Zo’bi Rasool shah s A El-Tantawy Department of Mathematical sciences College of SciencePrincess Nourah bint Abdulrahman UniversityPO Box 84428Riyadh 11671Saudi Arabia Department Mathematics and statistics Mutah UniversityAl-KarakJordan Department of Computer science and Mathematics Lebanese American UniversityBeirutLebanon Department of Physics Faculty of SciencePort Said UniversityPort Said 42521Egypt Department of Physics Faculty of ScienceAl-Baha UniversityAl-Baha P.O.Box 1988Saudi Arabia

The current investigation examines the fractional forced korteweg-de Vries(FF-kdV) equation,a critically significant evolution equation in various nonlinear branches of science. The equation in question and other associated equations are widely acknowledged for their broad applicability and potential for simulating a wide range of nonlinear phenomena in fluid physics, plasma physics, and various scientific domains. Consequently, the main goal of this study is to use the Yang homotopy perturbation method and the Yang transform decomposition method, along with the Caputo operator for analyzing the FF-kdV equation. The derived approximations are numerically examined and discussed. Our study will show that the two suggested methods are helpful, easy to use, and essential for looking at different nonlinear models that affect complex processes.

关键词： forced fractional kdV equation Caputo operator Yang homotopy perturbation method Yang transform decomposition method solitons

Twinning aspects and their efficient roles in wrought Mg alloys:A comprehensive review

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Journal of Magnesium and Alloys 2024年第6期12卷 2201-2230页

作者： s.s.A.shah Manping Liu Azim khan Farooq Ahmad M.R.Abdullah Xingquan Zhang shiwei Xu Zhen Peng school of Materials science and Engineering Jiangsu UniversityZhenjiang 212013China school of Mechanical Engineering Anhui University of TechnologyMáanshan 243002China College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082China

Twinning is widely recognized as an effective and cost-efficient method for controlling the microstructure and properties of wrought magnesium(Mg)***,twins play a crucial role in initiating dynamic recrystallization(DRX),while twin regions experience rapid recrystallization during static recrystallization(sRX).The activation of twinning can lead to changes in lattice orientation,significantly impacting the final texture in Mg *** active roles of twinning are influenced by various factors during the activation process,and the mobility of twin boundaries(TB)can be amplified by stress effects,dislocation interactions,and thermal ***,annealing treatments that involve proper segregation or precipitation on TBs serve to stabilize them,restraining their *** such as segregation may also alter the twinning propensity in Magnesium-rare earth(Mg-RE)***{10–11}contraction twins(CT)and{10–11}-{10–12}double twins(DT)can promote dynamic recrystallization(DRX),they also pose a risk as potential sources of voids and ***,understanding the nucleation and growth mechanisms of twinning is crucial,and these aspects are briefly reviewed in this *** the factors mentioned above,this article summarizes the recent research progress in this field,shedding light on advancements in recent eras.

关键词： Mg alloys Twinning Recrystallization Texture Mechanical properties

Understanding the corrosion and bio-corrosion behaviour of Magnesium composites – a critical review

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Journal of Magnesium and Alloys 2024年第3期12卷 890-939页

作者： Prithivirajan sekar s.k.Panigrahi Department of Mechanical Engineering Indian Institute of Technology MadrasChennai600036India Applied Magnesium Research Center Center of Excellence in Materials and Manufacturing for Futuristic MobilityIndian Institute of Technology MadrasChennai600036India

Realising the potential of Magnesium(Mg),several globally leading ventures have invested in the Mg industry,but their relatively poor corrosion resistance is a never ending saga till *** corrosion and bio-corrosion behaviour of Mg has gained research attention and still remains a hot topic in the application of automobile,aerospace and biomedical *** intrinsic high electrochemical nature of Mg limits their utilization in diverse *** scenario has prompted the development of Mg composites with an aim to achieve superior corrosion and bio-corrosion *** present review enlightens the influence of grain size(Gs),secondary phase,texture,type of matrix and reinforcement on the corrosion and bio-corrosion behaviour of Mg ***,the corrosion and bio-corrosion behaviour of Mg composites manufactured by primary and secondary processing routes are ***,the comprehensive corrosion and bio-corrosion mechanisms of these Mg composites are ***,the individual role of Gs,texture and corrosive medium on corrosion and bio-corrosion behaviour of Mg composites are clarified and *** challenges encountered,unanswered issues in this field are explained in detail and accordingly the scope for future research is *** review is presented from basic concrete background to advanced corrosion mechanisms with an aim of creating interest among the readers like students,researchers and industry experts from various research ***,the corrosion and bio-corrosion behaviour of Mg composites are critically reviewed for the first time to:(i)contribute to the body of knowledge,(ii)foster research and development,(iii)make breakthrough,and(iv)create life changing innovations in the field of Mg composite corrosion.

关键词： Corrosion Bio corrosion Magnesium alloys Magnesium composites Magnesium implants.

Hybrid-Vlasov simulation of soft X-ray emissions at the Earth’s dayside magnetospheric boundaries

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Earth and Planetary Physics 2024年第1期8卷 70-88页

作者： M.Grandin H.k.Connor s.Hoilijoki M.Battarbee Y.Pfau-kempf U.Ganse k.Papadakis M.Palmroth Department of Physics University of HelsinkiHelsinkiFinland NAsA Goddard space Flight Center GreenbeltMD20771USA space and Earth Observation Centre Finnish Meteorological InstituteHelsinkiFinland

solar wind charge exchange produces emissions in the soft X-ray energy range which can enable the study of near-Earth space regions such as the magnetopause,the magnetosheath and the polar cusps by remote sensing *** solar wind Magnetosphere Ionosphere Link Explorer(sMILE)and Lunar Environment heliospheric X-ray Imager(LEXI)missions aim to obtain soft Xray images of near-Earth space thanks to their soft X-ray Imager(sXI)*** earlier modeling works have already simulated soft X-ray images as might be obtained by sMILE sXI during its mission,the numerical models used so far are all based on the magnetohydrodynamics description of the space *** investigate the possible signatures of ion-kinetic-scale processes in soft Xray images,we use for the first time a global hybrid-Vlasov simulation of the geospace from the Vlasiator *** simulation is driven by fast and tenuous solar wind conditions and purely southward interplanetary magnetic *** first produce global X-ray images of the dayside near-Earth space by placing a virtual imaging satellite at two different locations,providing meridional and equatorial *** then analyze regional features present in the images and show that they correspond to signatures in soft X-ray emissions of mirrormode wave structures in the magnetosheath and flux transfer events(FTEs)at the *** results suggest that,although the time scales associated with the motion of those transient phenomena will likely be significantly smaller than the integration time of the sMILE and LEXI imagers,mirror-mode structures and FTEs can cumulatively produce detectable signatures in the soft X-ray *** instance,a local increase by 30%in the proton density at the dayside magnetopause resulting from the transit of multiple FTEs leads to a 12%enhancement in the line-of-sight-and time-integrated soft X-ray emissivity originating from this ***,a proton density increase by 14%in the magnetosheath

关键词： magnetosphere magnetosheath numerical simulation sMILE LEXI soft X-ray emissions hybrid-Vlasov model polar cusp flux transfer events mirror-mode waves

Infrared Fault Detection Method for Dense Electrolytic Bath Polar Plate Based on YOLOv5s

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Computers, Materials and Continua 2024年第3期80卷 4859-4874页

作者： Yu H. Hang Y. shi s. Wu k. Zhang Y. software Engineering Department of Computer Science Changzhou University Changzhou 213146 China Electrical Engineering Department of Computer Science Changzhou University Changzhou 213146 China

Electrolysis tanks are used to smelt metals based on electrochemical principles, and the short-circuiting of the pole plates in the tanks in the production process will lead to high temperatures, thus affecting normal production. Aiming at the problems of time-consuming and poor accuracy of existing infrared methods for high-temperature detection of dense pole plates in electrolysis tanks, an infrared dense pole plate anomalous target detection network YOLOv5-RMF based on You Only Look Once version 5 (YOLOv5) is proposed. Firstly, we modified the Real-Time Enhanced super-Resolution Generative Adversarial Network (Real-EsRGAN) by changing the U-shaped network (U-Net) to Attention U-Net, to preprocess the images; secondly, we propose a new Focus module that introduces the Marr operator, which can provide more boundary information for the network; again, because Complete Intersection over Union (CIOU) cannot accommodate target borders that are increasing and decreasing, replace CIOU with Extended Intersection over Union (EIOU), while the loss function is changed to Focal and Efficient IOU (Focal-EIOU) due to the different difficulty of sample detection. On the homemade dataset, the precision of our method is 94%, the recall is 70.8%, and the map@.5 is 83.6%, which is an improvement of 1.3% in precision, 9.7% in recall, and 7% in map@.5 over the original network. The algorithm can meet the needs of electrolysis tank pole plate abnormal temperature detection, which can lay a technical foundation for improving production efficiency and reducing production waste. Copyright © 2024 The Authors. Published by Tech science Press.

关键词： Focal-EIoU loss Infrared polar plate fault detection Marr boundary detection operator Real-EsRGAN YOLOv5

Unveiling health rights:A call to action for sex workers'HIV care in the Philippines

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Asian Pacific Journal of Tropical Medicine 2024年第1期17卷 45-46页

作者： sheikh Mohd saleem shah sumaya Jan Health section International NGONew DelhiIndia Department of Anatomy Govt.Medical CollegeSrinagarIndia

We are writing in response to the article titled“Addressing the needs and rights of sex workers for HIV healthcare services in the Philippines”[1].The article calls for attention on the significant challenges faced by sex workers in the Philippines in accessing HIV *** appreciate the article’s effort to examine these issues in *** would like to present a constant flow of thoughts in this letter while highlighting the positive aspects,potential obstacles,and additional points that contribute to this ongoing discussion.

关键词： workers action letter