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Chinese Herbal Medicine for Chemotherapy Induced Gastrointestinal Side Effects: A Systematic Review of Randomized Controlled Trials

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World Journal of Traditional Chinese Medicine 2017年第2期3卷 31-50页

作者： Chung-Wah Cheng Zhao-Xiang Bian Li-Dan Zhong justin cy wu Zhi-Xiu Lin Eric TC Ziea Vivian CW Wong Hong Kong Chinese Medicine Clinical Study Centre Hong Kong Baptist University School of Chinese Medicine Hong Kong Baptist University Faculty of Medicine The Chinese University of Hong Kong School of Chinese Medicine The Chinese University of Hong Kong Chinese Medicine Department Hospital Authority

Objective: To determine how safe and effective Chinese Herbal Medicine(CHM) is in alleviating the nausea, vomiting, oral ulceration,diarrhea and constipation for cancer patients with ***: Data sources: A systematic review of Chinese and English articles using Ovid SP, CNKI, VIP Database and Traditional Chinese Medicine Database System. Study selection: Only randomized controlled trials(RCTs) for the prevention or treatment of any one of gastrointestinal side effects, namely nausea, vomiting, oral ulceration, diarrhea and constipation, of CHM with or without western medicine(WM) vs WM, placebo or no treatment were included. Data Extraction: Independent extraction of articles was first performed by four medical students using predefined data fields. Then, all data, including study quality indicators, was checked by two ***: Eighty-six RCTs involving 7076 cancer patients were found and analyzed in this review. Because of the heterogeneity of study design and low overall methodological quality, only descriptive summaries were performed. Beneficial effects were found in some CHM interventions,regardless of being taken alone or taken with WM. Moreover, none of serious adverse effect was reported. However, same intervention had not been repeatedly investigated by different research ***: Implications of the analysis support the efficacy and safety of CHM for the management of gastrointestinal side ***, definite clinical recommendation for particular CHM intervention still cannot be made due to low methodological quality of included studies and lack of duplicated verification. Further large scale and high quality RCTs on the same CHM interventions are suggested.

关键词： Chinese herbal medicine Systematic review Chemotherapy induced side effects Gastrointestinal diseases

Key factors in developing the trinitrobenzene sulfonic acid-induced post-inflammatory irritable bowel syndrome model in rats

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World Journal of Gastroenterology 2012年第20期18卷 2481-2492页

作者： Hong-Yan Qin Hai-Tao Xiao justin cy wu Brian M Berman Joseph JY Sung Zhao-Xiang Bian School of Chinese Medicine Hong Kong Baptist University Hong Kong 999077 China Faculty of Medicine The Chinese University of Hong Kong.Hong Kong 999077 China Center for Integrative Medicine University of Maryland School of Medicine Baltimore MD 21201 United States

AIM:To investigate the key factors in developing the trinitrobenzene sulfonic acid(TNBS)-induced postinflammatory irritable bowel syndrome(PI-IBS)model in rats. METHODS:TNBS was administered to rats at the following conditions:(1)with different doses(20,10,5 mg/0.8 mL per rat);(2)with same dose in different concentrations(20 mg/rat,25,50 mg/mL);(3)in different ethanol percentage(25%,50%);and(4)at depth either 4 cm or 8 cm from *** 5 d and 4 wk after TNBS administration,inflammation severity and inflammation resolution were *** 4 and 8 wk after TNBS application,visceral hyperalgesia and enterochromaffin(EC)cell hyperplasia were assayed by abdominal withdrawal reflex test,silver staining and capillary electrophoresis. RESULTS:Our results showed that:(1)TNBS induced dose-dependent acute inflammation and inflammation *** 5 d post TNBS,the pathological score and myeloperoxidase(MPO)activity in all TNBS treated rats were significantly elevated compared to that of the control(9.48±1.86,8.18±0.67,5.78± 0.77 vs 0,and 3.55±1.11,1.80±0.82,0.97±0.08 unit/mg vs 0.14±0.01 unit/mg,P<0.05).At 4 wk post TNBS,the pathological score in high and median dose TNBS-treated rats were still significantly higher than that of the control(1.52±0.38 and 0.80±0.35 vs 0,P<0.05);(2)Intracolonic TNBS administration position affected the persistence of visceral *** 4 wk post TNBS,abdominal withdrawal reflex (AWR)threshold pressure in all TNBS-treated groups were decreased compared to that of the control(21.52 ±1.73 and 27.10±1.94 mmHg vs 34.44±1.89 mmHg,P<0.05).At 8 wk post TNBS,AWR threshold pressure in 8 cm administration group was still significantly decreased(23.33±1.33 mmHg vs 36.79±2.29 mmHg,P<0.05);(3)Ethanol percentage affected the TNBS-induced inflammation severity and visceral *** TNBS-25%ethanol-treated group,the pathological score and MPO activity were significantly lowered compared to that of the TNBS-50%ethanoltreated group,while AWR thres

关键词： Post-inflammatory Irritable bowel syndrome Rat model Trinitrobenzene sulfonic acid Key factors

ACUPUNCTURE AND RELATED THERAPIES VERSUS PROKINETICS FOR FUNCTIONAL DYSPEPSIA: OVERVIEW OF SYSTEMATIC REVIEWS AND NETWORK META-ANALYSIS

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World Journal of Traditional Chinese Medicine 2016年第2期 79-80页

作者： Robin ST Ho Xinyin wu Charlene HL Wong justin cy wu Vincent CH Chung Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong Hong Kong Institute of Integrative Medicine The Chinese University of Hong Kong

Introduction:Pharmacological interventions for functional dyspepsia(FD)have limited *** and related therapies could be used as an *** overview of systematic reviews(SRs)and network meta-analyses(NMA)were performed to

关键词： ACUPUNCTURE AND RELATED THERAPIES VERSUS PROKINETICS FOR FUNCTIONAL DYSPEPSIA OVERVIEW OF SYSTEMATIC REVIEWS AND NETWORK META-ANALYSIS FD

PREPARATION OF Cr-POLYSTYRENE COMPLEX BY METALVAPOR SYNTHESIS

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Chinese Chemical Letters 1996年第7期7卷 679-680页

作者： wu, SH Zhu, cy Huang, WP NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA

Chromium atom-hexane solution prepared in a metal atom reactor was transferred into a solution containing polystyrene in diethylene glycol dibutyl ether at -78 degrees C, followed by gently warming the mixture to 0 degrees C to react for two hows, yielding a brown-green solid product Ultraviolet-visible and infrared spectra showed that the product was a bi- (eta(6)-arene) chromium complex.

关键词： Cr PREPARATION OF Cr-POLYSTYRENE COMPLEX BY METALVAPOR SYNTHESIS

Fluorescence Quenching and Depolarization Studies on Segmental Motion of Poly (N, N-dimethylacrylamide)

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Chinese Chemical Letters 1997年第8期8卷 719-720页

作者： Zhu, cy wu, SH Li, LR NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA

A new polymer, poly(N, N-dimethylacrylamide), labeled with acenaphthylene has been synthesized. The rotational relaxation time of this polymer has been studied using steady state fluorescence depolarization measuremen... 详细信息

关键词： Fluorescence Quenching and Depolarization Studies on Segmental Motion of Poly N-dimethylacrylamide

STUDIES　OF　POLYMER　IMMOBILIZED　Pd－Cu　CLUSTER　CATALYSTS　PREPARED　BY　METAL　ATOM　SYNTHESIS（MVS）

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Chinese Chemical Letters 1995年第1期6卷 71-74页

作者： wu, SH Zhu, cy Zhu, JL Zheng, XS Nankai Univ Dept Chem Tianjin 300071 Peoples R China

Metal atoms of Pd and Cu produced by coevaporation in a metal atom reactor,was solvated at low temperature. These solvated metal atoms,were immobillized in. the polymer pore structure for preparing Pd-Cu bimetallic cluster *** measurements sbowed that both Pd and Cu,were in a zero-valent state. TEM and XRD resulta indicated that the Pd-Cu cluster particles,were very small. Catalytic tests. showed that these catalysts are very active for 4-methyl-3-penten-2-one hydrogenation.

关键词： Pd IMMOBILIZED CLUSTER ATOM BY MVS Cu

TWO　NOVEL　EASILY　PREPARED　CHIRAL　POLYSILOXANE　STATIONARY　PHASES　FOR　GC　RESOLUTION　OF　ENANTIOMERS

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Chinese Chemical Letters 1995年第1期6卷 53-54页

作者： Zhou, XC Lu, XR wu, cy Chen, YY wuhan Univ Dept Chem Wuhan 430072 Peoples R China

Tuv new substituted chiral polysiloxanes were synthesized by the reaction of polymethylhydrosiloxan with chiral moieties containing alkenes derived from D-tartaric acid and L-phenylalanine,The primary GC characteristics of the two phases were also *** use of charal stationary phases (CSPs) to affect separation of enantiomers of organiccomPOunds have increased dramatically in the last decade. The development covalently bonding Nisobutyryl--valine tert--butylamide or benzyloxycarbonyl--L--vallne with silicone has improved thermalstability and these phases can resolve most protein amino acid enantiomers in a short time[1-3j. Butthey are expensive and their preparation is difficult.

关键词： GC RESOLUTION PHASES OF STATIONARY EASILY CHIRAL

Psychological, social, and sexual challenges affecting men receiving male infertility treatment: a systematic review and implications for clinical care

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Asian Journal of Andrology 2023年第4期25卷 448-453页

作者： Winston wu justin La Kathryn M Schubach Daniel Lantsberg Darren J Katz Department of Urology Western HealthSt AlbansVIC 3021Australia Department of Urology Kaiser Permanente San Rafael Medical CenterSan RafaelCA 94903USA Men’s Health Melbourne MelbourneVIC 3000Australia Reproductive Services Unit The Royal Women’s HospitalParkvilleVIC 3052Australia Melbourne IVF East MelbourneVIC 3002Australia Department of Surgery Western PrecinctUniversity of MelbourneParkvilleVIC 3010Australia

In recent years, social research surrounding the consequences of infertility has increasingly focused on the male perspective;however, a gap exists in the understanding of men’s experiences of male infertility treatment. This review aims to synthesize theexisting evidence concerning the psychological, social, and sexual burden of male infertility treatment on men, as well as patientneeds during clinical care. A systematic search identified 12 studies that are diverse in design, setting, and methods. Psychologicalevaluations have found that urological surgery may have a lasting impact on infertility-specific stress, and treatment failure canlead to feelings of depression, grief, and inadequacy. Men tended to have an avoidant coping mechanism throughout fertilitytreatment, and their self-esteem, relationship quality, and sexual functions can be tied to outcomes of treatment. Partner bonds canbe strengthened by mutual support and enhanced communication;couple separation, however, has been noted as a predominantreason for discontinuing male infertility treatment and may be associated with difficult circumstances surrounding severe maleinfertility. Surgical treatments can affect the sexual functioning of infertile men;however, the impact of testicular sperm extractionoutcomes appears to be psychologically driven whereas the improvements after microsurgical varicocelectomy are only evident inhypogonadal men. Clinically, there is a need for better inclusion, communication, education, and resource provision, to addressreported issues of marginalization and uncertainty in men. Routine psychosocial screening in cases of severe male infertility andfollow-up in cases of surgical treatment failure are likely beneficial.

关键词： male infertility male infertility treatment patient experience patient-centered care psychosocial sexual

WS2 nanoflakes from nanotubes for electrocatalysis

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Nano Research 2013年第12期6卷 921-928页

作者： Charina L. Choi Ju Feng Yanguang Li justin wu Alia Zak Reshef Tenne Hongjie Dai Department of Chemistry Stanford University California 94305 USA Department of Science Holon Academic Institute of Technology Holon 58102 Israel Department of Materials and Interfaces Weizmann Institute Rehovot 76100 Israel

Next-generation catalysts for water splitting are crucial towards a renewable hydrogen economy. MoS2 and WS2 represent earth-abundant, noble metal cathode alternatives with high catalytic activity at edge sites. One challenge in their development is to nanostructure these materials in order to achieve increased performance through the creation of additional edge sites. In this work, we demonstrate a simple route to form nanostructured-WS2 using sonochemical exfoliation to break interlayer and intralayer bonds in WS2 nanotubes. The resulting few-layer nanoflakes are -100 nm wide with a high density of edge sites. WS2 nanoflakes are utilized as cathodes for the hydrogen evolution reaction （HER） and exhibit superior performance to WS2 nanotubes and bulk particles, with a lower onset potential, shallower Tafel slope and increased current density. Future work may employ ultra-small nanoflakes, dopant atoms, or graphene hybrids to further improve electrocatalytic activity.

关键词： tungsten disulfide nanotubes nanostructuring hydrogen evolution