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中药松花粉的化学成分及现代应用研究进展

沈阳药科大学学报 2024年第10期41卷 1275-1286,1297页

作者：李荣胜付庆帅郭俊红谢富玲张兴明潘一峰上海黄海制药有限责任公司上海200942 上海现代中医药股份有限公司上海200050

目的综述松花粉的品种特点、分布、化学成分、药理作用及现代制剂应用研究进展,为其药食两用资源的深入开发利用提供参考。方法通过查阅书籍、Web of science、PubMed、CNKI等数据库以及CNIPA、SAMR、NMPA等网站中已发表松花粉相关文献... 详细信息

目的综述松花粉的品种特点、分布、化学成分、药理作用及现代制剂应用研究进展,为其药食两用资源的深入开发利用提供参考。方法通过查阅书籍、Web of science、PubMed、CNKI等数据库以及CNIPA、SAMR、NMPA等网站中已发表松花粉相关文献进行分析和归纳总结。结果松花粉药食同源,含有多种化学成分,包括黄酮类、甾醇类、多糖类、脂肪类等。具有抗氧化、抗炎、增强免疫力等多种药理活性。结论松花粉具有广泛的药理作用和食用价值,其在药用、食用领域有待更深入的研究,应完善其质量标准、拓宽其临床应用以及研制开发成新制剂.

关键词：松花粉化学成分药理作用现代应用

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泛生态立体智慧监测预警溯源系统设计

自动化与仪器仪表 2024年第9期 144-149页

作者：戈燕红李少琳郭隽虹舒少君区梓峰广东盈峰科技有限公司广东佛山528000 清华大学深圳国际研究生院广东深圳518000 广东省湛江生态环境监测中心站广东湛江524000

应用大数据技术、双中台技术、5G技术、北斗技术、3D-GIS技术、算法模型技术、现代传感技术、自动控制技术,建立泛生态立体智慧监测预警溯源系统。通过建立“天地一体化”环境立体监测体系,全面提升环境监测自动化、智能化水平;通过建... 详细信息

应用大数据技术、双中台技术、5G技术、北斗技术、3D-GIS技术、算法模型技术、现代传感技术、自动控制技术,建立泛生态立体智慧监测预警溯源系统。通过建立“天地一体化”环境立体监测体系,全面提升环境监测自动化、智能化水平;通过建设污染预警溯源系统,快速捕捉环境质量异常,并确定污染类型,最大程度减少生态环境破坏与影响。对生态环境大数据进行深度分析和挖掘,提高了政府管理决策效率,深化了行政管理体制改革,产生了良好的经济和社会效益。

关键词：大数据技术双中台技术环境立体监测污染预警溯源

High Fe^(LS)(C)electrochemical activity of an iron hexacyanoferrate cathode boosts superior sodium ion storage

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Carbon Energy 2023年第5期5卷 67-77页

作者： junhong guo Fan Feng Shiqiang Zhao Zhenhai Shi Rui Wang Meng Yang Fangfang Chen Suli Chen Zi-Feng Ma Tianxi Liu Key Laboratory of Synthetic and Biological Colloids Ministry of EducationInternational Joint Research Laboratory for Nano Energy CompositesSchool of Chemical and Material EngineeringJiangnan UniversityWuxiChina Department of Chemical Engineering Shanghai Electrochemical Energy Devices Research CenterShanghai Jiao Tong UniversityShanghaiChina College of Chemistry and Materials Engineering Wenzhou UniversityWenzhouChina

Sodium iron hexacyanoferrate(FeHCF)is one of the most promising cathode materials for sodium-ion batteries(SIBs)due to its low cost theoretical ***,the low electrochemical activity of Fe^(LS)(C)in FeHCF drags down its practical capacity and potential ***,FeHCF with high Fe^(LS)(C)electrochemical activity(C-FeHCF)is synthesized via a facile citric acid-assisted solvothermal *** the cathode of SIBs,C-FeHCF shows superior cycling stability(ca.87.3%capacity retention for 1000 cycles at 10 C)and outstanding rate performance(ca.68.5%capacity retention at 50 C).Importantly,the contribution of Fe^(LS)(C)to the whole capacity was quantitatively analyzed via combining dQ/dV and discharge curve for the first time,and the index reaches 44.53%for C-FeHCF,close to the theoretical ***-situ X-ray diffraction proves the structure stability of C-FeHCF during charge-discharge process,ensuring its superior cycling ***,the application feasibility of the C-FeHCF cathode in quasi-solid SIBs is also *** quasi-solid SIBs with the C-FeHCF cathode exhibit excellent electrochemical performance,delivering an initial discharge capacity of 106.5 mAh g^(−1) at 5 C and high capacity retention of 89.8%over 1200 *** work opens new insights into the design and development of advanced cathode materials for SIBs and the beyond.

关键词： cathode material electrochemical activity sodium-ion batteries sodium iron hexacyanoferrate structural evolution

抗酸染色联合PAS染色和六胺银染色在感染性疾病病理学实验教学中的应用

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中国组织化学与细胞化学杂志 2024年第2期33卷 201-207,200页

作者：瞿智玲郭俊红王曦杨茹梦倪娟段亚琦华中科技大学基础医学国家级实验教学示范中心武汉430030 华中科技大学同济医学院基础医学院病理学系武汉430030 华中科技大学附属同济医院病理研究所武汉430030

为配合医学整合课程体系改革,结合临床病理诊断常用的感染性疾病的辅助诊断方法,将抗酸染色、高碘酸-Schiff(periodic acid-Schiff,PAS)染色和六胺银染色阳性病例切片引入病理学感染性疾病章节的实验教学,显示出病变组织致病微生物。通... 详细信息

为配合医学整合课程体系改革,结合临床病理诊断常用的感染性疾病的辅助诊断方法,将抗酸染色、高碘酸-Schiff(periodic acid-Schiff,PAS)染色和六胺银染色阳性病例切片引入病理学感染性疾病章节的实验教学,显示出病变组织致病微生物。通过对不同班级进行问卷调研,绝大多数同学认可特殊染色在感染性疾病章节中的应用,认为不仅丰富了课堂内容,学习了结核杆菌和真菌在病变组织中的形态学特征及其导致的组织病理变化,而且加深了对感染性疾病理论知识的理解,深刻认识到病理学研究内容除了疾病的病理变化之外,还要探讨疾病发生的病因以及好发部位。同时,这些增加的特殊染色切片改变了本章节实验教学切片普通光学显微镜下色彩的单调性——单一的“红-蓝”色调,丰富了镜下色彩,提高了学生的学习兴趣,活跃了课堂气氛。

关键词：感染性疾病实验教学抗酸染色 PAS染色六胺银染色

CO_(2)驱油封存泄漏风险管理系统及应用研究

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油气藏评价与开发 2024年第1期14卷 91-101页

作者：张志升吴向阳吴倩王冀星林汉弛郭军红王锐李金花林千果延长油田股份有限公司杏子川采油厂陕西延安717400 华北电力大学环境科学与工程学院北京102206 中国石化石油勘探开发研究院北京102206 上海交通大学环境科学与工程学院上海201306 上海交通大学碳中和发展研究院上海201306

CO_(2)驱油封存技术在提高原油采收率的同时能实现大规模CO_(2)封存。然而,驱油封存过程伴随着多种CO_(2)泄漏风险。针对以往CO_(2)泄漏风险管理系统的缺乏,特别是缺少基于在线监测的管理系统,难以支撑动态的风险管理,研究基于CO_(2)驱... 详细信息

CO_(2)驱油封存技术在提高原油采收率的同时能实现大规模CO_(2)封存。然而,驱油封存过程伴随着多种CO_(2)泄漏风险。针对以往CO_(2)泄漏风险管理系统的缺乏,特别是缺少基于在线监测的管理系统,难以支撑动态的风险管理,研究基于CO_(2)驱油封存泄漏风险管理体系的构建,开发了集成多环境实时风险识别和评估、多空间风险预测、多层级风险预警和全过程风险控制的动态CO_(2)泄漏风险管理系统,并应用于鄂尔多斯盆地延长石油CO_(2)驱油封存示范项目。案例应用研究表明,所开发的CO_(2)泄漏风险管理系统可以全空间动态识别CO_(2)驱油封存过程的各种泄漏风险,有效支撑泄漏风险的动态管理,为CO_(2)驱油封存项目提供全面及时的安全保障。

关键词： CO_(2)驱油封存 CO_(2)泄漏风险管理风险预测风险预警决策支持

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AVP(4-8) Improves Cognitive Behaviors and Hippocampal Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

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Neuroscience Bulletin 2020年第3期36卷 254-262页

作者： Xiumin Zhang Fang Zhao Chenfang Wang Jun Zhang Yu Bai Fang Zhou Zhaojun Wang Meina Wu Wei Yang junhong guo Jinshun Qi Department of Neurology First HospitalShanxi Medical UniversityTaiyuan 030001China Department of Physiology Key laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuan 030001China

Memory deficits with aging are related to the neurodegeneration in the brain, including a reduction in arginine vasopressin(AVP) in the brain of patients with Alzheimer’s disease(AD). AVP(4-8), different from its precursor AVP, plays memory enhancement roles in the CNS without peripheral side-effects. However, it is not clear whether AVP(4-8) can improve cognitive behaviors and synaptic plasticity in the APP/PS1 mouse model of AD. Here, we investigated for the first time the neuroprotective effects of AVP(4-8) on memory behaviors and in vivo long-term potentiation(LTP) in APP/PS1-AD *** results showed that:(1) APP/PS1-AD mice had lower spontaneous alternation in the Y-maze than wild-type(WT) mice, and this was significantly reversed by AVP(4-8);(2) the prolonged escape latency of APP/PS1-AD mice in the Morris water maze was significantly decreased by AVP(4-8), and the decreased swimming time in target quadrant recovered significantly after AVP(4-8) treatment;(3) in vivo hippocampal LTP induced by high-frequency stimulation had a significant deficit in the AD mice, and this was partly rescued by AVP(4-8);(4) AVP(4-8)significantly up-regulated the expression levels of postsynaptic density 95(PSD95) and nerve growth factor(NGF)in the hippocampus of AD mice. These results reveal the beneficial effects of AVP(4-8) in APP/PS1-AD mice,showing that the intranasal administration of AVP(4-8)effectively improved the working memory and long-term spatial memory of APP/PS1-AD mice, which may be associated with the elevation of PSD95 and NGF levels in the brain and the maintenance of hippocampal synaptic plasticity.

关键词： AVP(4-8) APP/PS1 transgenic mice Cognitive behavior Synaptic plasticity In vivo hippocampal LTP

Mining,characterization,and exploitation of EST-derived microsatellites in Gossypium barbadense

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Chinese Science Bulletin 2010年第18期55卷 1889-1893页

作者： LU YuanDa CAI CaiPing WANG Lei LIN ShaoYan ZHAO Liang TIAN LiangLiang LU junhong ZHANG TianZhen guo WangZhen National Key Laboratory of Crop Genetics & Germplasm Enhancement Cotton Research Institute Nanjing Agricultural University Nanjing210095 China

Simple sequence repeats(SSRs) have been widely applied as molecular markers in genetic ***,the number of expressed sequence tags(ESTs) and SSR markers from Gossypium barbadense is fewer than those from other cotton *** this study,EST-SSR distribution from *** was characterized and new ***-derived EST-SSR markers were determined on the basis of the ESTs obtained by randomly sequencing 2 cDNA libraries associated with fiber development in *** mining 9697 non-redundant ESTs,a total of 638 SSR loci derived from 595 ESTs were *** ***,the frequency of ESTs containing SSRs was 6.13%,with an average of 1 SSR in every 10.4 kb of EST ***,trinucleotide was found to be the most abundant repeat type among 2-6-nucleotide repeat *** accounted for 26.6% of the total,followed by the hexanucleotide(26.0%) and pentanucleotide repeats(25.9%).Among all the repeat motifs,(AAG)n accounted for the highest ***-SSR primer pairs were developed using the Primer3 program,and the redundant primers were removed using the virtual PCR *** a result,380 non-redundant EST-SSR primer pairs were developed and used to detect polymorphisms between the mapping parents *** 'TM-1' and *** 'Hai7124' for constructing linkage groups in cultivated allotetraploid *** of these,98(25.8%) primer pairs detected ***,95 polymorphic loci from 82 primer pairs were integrated into the backbone genetic map;of these,42 were mapped into the A subgenome and 53 into the D *** present work provided the foundation for constructing saturated genetic maps and conducting comparative genomic studies on different cotton species.

关键词：美国东部微卫星挖掘鉴定海岛开发棉花时间

Modeling and Experimental Study on Kinetics of Methane Hydrate Formation in Pure Water

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石油学报（石油加工） 1997年第S1期13卷 3-13页

作者： Qiu junhong , guo Tianmin (High Pressure Fluid Phase Behavior & Property Research Laboratory, University of Petroleum, Beijing 100083)

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关键词： hydrate formation kinetics modeling experimental measurement methane

Protection of Omicron Sub-Lineage Infection Against Reinfection with Another Omicron Sub-Lineage:Systematic Review,Meta-Analysis,and Meta-Regression-Worldwide,2022-2023

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China CDC weekly 2024年第26期6卷 624-628,I0001-I0009页

作者： Xu guo Zuyao Cheng junhong Li Yudan Song Hui Zheng Yamin Wang Chao Ma Zijian Feng National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease National Immunization ProgramChinese Center for Disease Control and PreventionBeijingChina Chinese Preventive Medicine Association BeijingChina

Summary What is already known about this topic?Both the decline in immunity over time and the evolution of the virus play a role in the level of protection offered by a prior *** is added by this report?Point estimates indicated variations in protection levels based on the initial infecting variant and the reinfecting *** was a consistent correlation between real-world protection,antigenic distance,and humoral immunity ***,shorter antigenic distances and higher humoral immunity levels corresponded to enhanced real-world *** are the implications for public health practice?Our findings suggest that virological and immunological studies could help identify and assess the epidemic risk posed by new variants before they become *** incorporation of the latest variants into the antigen components of the coronavirus disease 2019(COVID-19)vaccines can significantly contribute to effective epidemic prevention and control measures.

关键词： immunity prevention shorter