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Combined use of non-biological artif icial liver treatments for patients with acute liver failure complicated by multiple organ dysfunction syndrome

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World Journal of Emergency Medicine 2014年第3期5卷 214-217页

作者： Mao-qin Li jun-xiang ti Yun-hang Zhu Zai-xiang Shi Ji-yuan Xu Bo Lu Jia-qiong Li Xiao-meng Wang Yan-jun Xu Department of Intensive Care Xuzhou Central HospitalAffiliated to School of MedicineSoutheast University

BACKGROUND:Acute liver failure(ALF) caused by viral and non-viral hepatitis is often accompanied with severe metabolic disorders,the accumulation of toxic substances and continuous release and accumulation of a large number of endogenous toxins and inflammatory mediators. The present study aimed to investigate the effects of various combined non-biological artif icial liver treatments for patients with acute liver failure(ALF) complicated by multiple organ dysfunction syndrome(MODS).METHODS:Thirty-one patients with mid- or late-stage liver failure complicated by MODS(score 4) were randomly divided into three treatment groups:plasmapheresis(PE) combined with hemoperfusion(HP) and continuous venovenous hemodiafiltration(CVVHDF),PE+CVVHDF,and HP+CVVHDF,respectively. Heart rate(HR) before and after treatment,mean arterial pressure(MAP),respiratory index(PaO2/FiO2),hepatic function,platelet count,and blood coagulation were ***:Signifi cant improvement was observed in HR,MAP,PaO2/FiO2,total bilirubin(TBIL) and alanine aminotransferase(ALT) levels after treatment(Ptime(PT) and albumin were signifi cantly improved only in the PE+CVVHDF and PE+HP+CVVHDF groups(Ptients was 58.1%(18/31),viral survival rate 36.4%(4/11),and non-viral survival rate 70%(14/20).CONCLUSION:Liver function was relatively improved after treatment,but PE+HP+CVVHDF was more efficient for the removal of toxic metabolites,especially bilirubin. The survival rate was signifi cantly higher in the patients with non-viral liver failure than in those with viral liver failure.

关键词： Severe acute liver failure Artificial liver Plasma exchange Hemoperfusion Continuous veno-venous hemodiafi ltration

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Comparison of contribution of sub-rapid cooling and shear deformation to refinement of Fe-rich phase in hypereutectic Al-Fe alloy during rheo-extrusion

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Journal of Iron and Steel Research International 2020年第11期27卷 1294-1302页

作者： xiang Wang Ren-guo Guan Yuan-dong Li ti-jun Chen State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of TechnologyLanzhou 730050GansuChina School of Materials Science and Engineering Northeastern UniversityShenyang 110819LiaoningChina

A hypereutectic Al-3Fe(wt.%)alloy was subjected by rheo-extrusion,and the effect of sub-rapid cooling and shear deformation on the refinement of Fe-rich phase was *** results showed that both the primary Fe-rich phase and eutectic Fe-rich phase in the solidified Al-Fe alloy were finer than the platelike Fe-rich phase in the as-cast Al-Fe alloy with the same content of *** solidified Al-Fe alloy was subjected to three stages of shear deformation,and both the primary Fe-rich phase and eutectic Fe-rich phase were fractured and the average length was refined to 400 nm,while Fe-rich phase in the as-cast Al-3Fe(wt.%)alloy was platelike and its average length was 40 *** tensile strength and elongation of the hypereutectic Al-3Fe(wt.%)alloy containing nanosized Fe-rich phase were 162 MPa and 25.78%while those of the as-cast AI-3Fe(wt.%)alloy containing coarse platelike Fe-rich phase were 102 MPa and 16.84%,*** the refineme nt of Fe-rich phase in hypereutectic Al-Fe alloy during rheo-extrusion,the three stages of shear deformation contributed more than sub-rapid cooling.

关键词： Fe-rich phase Hypereutectic Al-Fe alloy Refinement Sub-rapid cooling Shear deformation

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Effect of Wave Nonlinearity on the Instantaneous Seabed Liquefaction

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China Ocean Engineering 2024年第1期38卷 93-103页

作者： WANG Zhao-jun SUI ti-ti ZHANG Chi PAN jun-ning Key Laboratory of Port Waterway and Sedimentation Engineering of the Ministry of TransportNanjing Hydraulic Research InstituteNanjing 210024China Key Laboratory of Coastal Disaster and Protection(Hohai University) Ministry of EducationNanjing 210098China The National Key Laboratory of Water Disaster Prevention Nanjing 210098China

The nonlinear variation of wave is commonly seen in nearshore area,and the resulting seabed response and liquefaction are of high concern to coastal *** this study,an analytical formula considering the nonlinear wave skewness and asymmetry is adopted to provide wave pressure on the seabed *** liquefaction depth attenuation coefficient and width growth coefficient are defined to quantitatively characterize the nonlinear effect of wave on seabed *** on the 2D full dynamic model of wave-induced seabed response,a detailed parametric study is carried out in order to evaluate the influence of the nonlinear variation of wave loadings on seabed ***,new empirical prediction formulas are proposed to fast predict the maximum liquefaction under nonlinear *** indicate that(1)Due to the influence of wave nonlinearity,the vertical transmission of negative pore water pressure in the seabed is hindered,and therefore,the amplitude decreases significantly.(2)In general,with the increase of wave nonlinearity,the liquefaction depth of seabed decreases *** under asymmetric and skewed wave loading,the attenuation of maximum seabed liquefaction depth is the most significant among all the nonlinear wave ***,highly skewed wave can cause the liquefaction depth of seabed greater than that under linear wave.(3)The asymmetry of wave pressure leads to the increase of liquefaction width,whereas the influence of skewedness is not significant.(4)Compared with the nonlinear waveform,seabed liquefaction is more sensitive to the variation of nonlinear degree of wave loading.

关键词： nonlinear wave seabed response seabed liquefaction numerical simulation liquefaction prediction

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Microstructure and crystal growth direction of Al-Mg alloy

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China Foundry 2015年第2期12卷 129-135页

作者： ti-jun Chen Hai-yang Guo xiang-wei Li Yuan Hao Key Laboratory of Gansu Advanced Nonferrous Metal Materials Lanzhou University of Technology

The microstructures and crystal growth directions of permanent mould casting and directionally solidified Al-Mg al oys with different Mg contents have been investigated. The results indicate that the effect of Mg content on microstructure is basical y same for the al oys prepared by these two methods. The primary grains change from cel ular crystals to developed columnar dendrites, and then to equiaxed dendrites as the Mg content is increased. Simultaneously, both the cel ular or columnar grain region and the primary trunk spacing decrease. Al of these changes are mainly attributed to the constitutional supercooling resulting from Mg element. Comparatively, the cellular or columnar crystals of the directionally solidified alloys are straighter and more paral el than those of the permanent mould casting al oys. These have straight or wavy grain boundaries, one of the most important microstructure characteristics of feathery grains. However, the transverse microstructure and growth direction reveal that they do not belong to feathery grains. The Mg seemingly can affect the crystal growth direction, but does not result in the formation of feathery grains under the conditions employed in the study.

关键词： Al-Mg alloy microstructure crystal growth direction feathery grains permanent mould casting directional solidifi cation

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Scaling analysis of current influence on Hastelloy surface roughness in electro-polishing process

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Rare Metals 2019年第2期38卷 142-150页

作者： Feng Feng xiang-Song Zhang ti-Ming Qu Yan-Yi Zhang xiang Qian Bin-Bin Liu jun-Long Huang Ping-Fa Feng Division of Advanced Manufacturing Graduate School at Shenzhen Tsinghua University The State Key Laboratory of Tribology Department of Mechanical Engineering Tsinghua University Department of Physics Tsinghua University

In this study, a series of Hastelloy tapes were electro-polished, and the dividing method was used to carry out a detailed investigation on the influence of polishing current(I) on root mean square(R_q) at various image scales(L). The electro-polishing is found to be effective mainly at L smaller than 10μm, where the R_q–I relationship could be fitted by an exponential decay function with a residual roughness value. An approximate model of electro-polishing process was established to interpret the exponential decay function. This study provides a quantified insight into the electro-polishing process, which could help to obtain more understanding of its mechanism.

关键词： Surface roughness Scaling analysis Root mean square Atomic force microscopy Electro-polishing

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Thickness and sp3 bond modulation of（ti/tetrahedral amorphous carbon）_n multilayer coatings

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Tungsten 2025年第1期 152-160页

作者： Zhi-jun Xie Jia-Lin Li Ling Gong xiang-Li Zhong Hong-Jia Song Jin-Bin Wang National-Provincial Laboratory of Special Function Thin Film Materials School of Materials Science and Engineering Xiangtan University

The durability of wear-resistant tetrahedral amorphous carbon（ta-C） coatings is intimately linked to their thickness and the concentration of *** enhance the lifespan of the coatings,we have prepared a multilayer coating consisting of alternating layers of ti and ta-C,denoted as（ti/ta-C）_n,using arc ion plating.A multi-layer structure in conjunction with stage cooling is employed to enhance the thickness and promote *** results indicate that the ID/IGvalue,representing the ratio of the intensity of the D peak to that of the G peak in Raman spectroscopy,decreases from 0.85 when no stage cooling is applied to 0.35 when stage cooling is employed,suggesting an enhancement in the fraction of sp3bonds within the *** obtained（ti/ta-C）_n multilayer coating without peeling off has a maximum thickness of 1.14 μm,which is almost double that of the ta-C coating single layer *** the same time,the coating has a low coefficient of friction,down to 0.069,and maintains excellent friction properties with a wear rate of 3.4×10-6mm3·N-1·*** results conclusively show that the preparation technology can enhance both thickness and sp3bonding in ta-C coatings,significantly expanding their utility across tools,molds,and precision engineering components.

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Non-Markovianity of a qubit coupled with an isotropic Lipkin–Meshkov–Glick bath

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Chinese Physics B 2015年第10期24卷 59-66页

作者：田立君提敏敏翟向东 Department of Physics Shanghai University

We study the non-Markovianity of the single qubit system coupled with an isotropic Lipkin-Meshkov-Glick（LMG）model by an effective method proposed by Breuer et al.（Breuer H P and Piilo J 2009 Europhys. Lett. 85 5004）. It is discovered that the non-Markovianity is concerned with the quantum phase transitions（QPTs）. In the open system, we present that the strong coupling inside the bath and the strong interaction between the system and bath can enhance the degree of non-Markovianity. Moreover, the non-Markovianity is stronger and more sensitive for the bath in the symmetric phase than the symmetry broken phase.

关键词： non-Markovianity qubit dynamics LMG model

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A new broadband differential phase shifter fabricated using a novel CRLH structure

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第10期8卷 1568-1572页

作者： ZOU Yong-zhuo LIN Zhi-li LING ti YAO jun HE Sailing state Key Laboratory of Modern Optical Instrumentation Zhejiang University Hangzhou 310027. China Division of Electromagnetic Theory Alfven Laboratory Royal Institute of Technology S-I00 44 Stockholm Sweden

Broadband phase shifters are mostly proposed and fabricated based on the scheme proposed by Shiffman, which uses a coupled line with far ends connected together and a uniform transmission line to give a differential phase shift. Based on the unique dispersion property of the composite right/left-handed (CRLH) metamaterial structure, a new configuration is presented in this paper for fabricating the broadband differential phase shifter, which employs a novel CRLH metamaterial structure as one of the differential phase-shift arms, instead of the conventional coupled line. The new circuit can achieve a phase shift of 90° in an operational bandwidth as broad as one octave and its phase deviations are quite small. An original design of the novel broadband phase shifter is presented, in which the artificial CRLH structure was implemented by microstrip quasi-lumped elements. Both the simulated and measured results of the 90° broadband differential phase shifter are presented.

关键词： Broadband Differential phase shifter Composite right/left-handed (CRLH) metamaterial structure Quasi-lumpedelements

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Risk Factors for Mortality in Critically Ill Patients with Coagulation Abnormalities:A Retrospective Cohort Study

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Current Medical Science 2024年第5期44卷 912-922页

作者： Qiu-yu GUO jun PENG ti-chao SHAN Miao XU Department of Hematology Qilu Hospital of Shandong UniversityJinan250012China Department of Critical Care Medicine Qilu Hospital of Shandong UniversityJinan250012China

Objective Coagulation abnormalities are common and prognostically significant in intensive care units(ICUs)and are associated with increased *** study aimed to explore the association between the levels of coagulation markers and the risk of mortality among ICU patients with coagulation *** This retrospective study investigated patients with coagulation abnormalities in the ICU between January 2021 and December *** initial point for detecting hemostatic biomarkers due to clinical assessment of coagulation abnormalities was designated day *** were followed up for 28 days,and multivariate logistic regression analysis was utilized to identify risk factors for *** Of the 451 patients analyzed,115 died,and 336 were alive at the end of the 28-day *** analysis revealed that elevated thrombin-antithrombin complex(TAT),tissue plasminogen activator inhibitor complex(tPAIC),prolonged prothrombin time,and thrombocytopenia were independent risk factors for *** nonovert disseminated intravascular coagulation(DIC)patients,older age and thrombocytopenia were associated with increased risks of mortality,whereas elevated levels of plasminα2-plasmin inhibitor complex(PIC)were found to be independent predictors of *** patients with overt DIC,elevated levels of tPAIC were independently associated with increased risks of ***,thrombocytopenia was independently associated with increased risks of mortality in patients with *** Coagulation markers such as the TAT,tPAIC,PIC,and platelet count were significantly associated with mortality,underscoring the importance of maintaining a balance between coagulation and *** findings highlight the potential for targeted therapeutic interventions based on specific coagulation markers to improve patient outcomes.

关键词： blood coagulation markers mortality risk factors disseminated intravascular coagulation intensive care unit

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Advances in fabricating spherical alginate hydrogels with controlled particle designs by ionotropic gelation as encapsulation systems

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Particuology 2016年第1期14卷 44-60页

作者： jun-Yee Leong Weng-Hoong Lam Kiang-Wei Ho Wan-Ping Voo Micky Fu-xiang Lee Hui-Peng Lim Swee-Lu Lim Beng-ti Tey Denis Poncelet alan Lagoon Selatan Bandar Sunway Selangor 46150 Malaysia Advanced Engineering Platform Monash University Malaysia Jalan Lagoon Selatan Bandar Sunway Selangor 46150 Malaysia Oniris UMR CNRS 6144 GEPEA rue de la Geraudiere BP82225 Nantes 44322 France

Alginate is a biopolymer that has exceptional gelling properties, which allow easy gel formation under safe and mild conditions. Consequently, it is often used to encapsulate a variety of cargos, such as cells, enzymes, and lipids, and is typically employed as a model to study hydrogel-based encapsulation sys- tems. Since the first use of alginate in the encapsulation field in the 1970s, many methods have been developed to produce alginate hydrogel particles of different sizes, structures, and morphologies. This review provides an overview of the current progress in the fabrication of alginate hydrogels with vari- ous particle designs, including a discussion of dispersion techniques to pre-template alginate particles, gelation mechanisms, considerations in selecting suitable fabrication methods, and future directions.

关键词： Alginate lonotropic gelation Immobilization Encapsulation Hydrogel

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