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Delivery of essential pediatric congenital surgical care within Brazil’s universal health coverage system:a national survey of pediatric surgeons

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World Journal of Pediatric Surgery 2023年第3期6卷 136-146页

作者： Paul R Truche Abbie E Naus Fabio Botelho julia ferreira Alexis Bowder Luke Caddell Kathrin Zimmerman Isabella Maria de Freitas Faria Bellisa Caldas Lopes Eduardo Corrêa Costa Fernanda Lage Lima Dantas Augusto J S A Cavalcante Carlos A L B Carvalho Simone Abib David P Mooney Nivaldo Alonso Program in Global Surgery and Social Change Harvard Medical SchoolBostonMassachusettsUSA Department of Surgery Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA Department of Pediatric Surgery McGill UniversityMontrealQuébecCanada Department of Surgery Medical College of WisconsinMilwaukeeWisconsinUSA Division of Otolaryngology-Head and Neck Surgery Department of SurgeryUniversity of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA School of Medicine UFMGBelo HorizonteMinas GeraisBrazil Department of Pediatric Surgery Instituto de Medicina Integral Professor Fernando FigueiraRecifeBrazil Department of Pediatric Surgery Hospital de Clinicas de Porto AlegrePorto AlegreBrazil Department of Pediatric Surgery Federal University of AcreRio BrancoBrazil Department of Pediatric Surgery Hospital Santa Casa de Belo HorizonteBelo HorizonteBrazil Department of Pediatric Surgery Federal University of Mato GrossoCuiabaBrazil Department of Pediatric Surgery UNIFESPSao PauloBrazil Department of Pediatric Surgery Boston Children's HospitalBostonMassachusettsUSA Department of Plastic Surgery University of São Paulo Institute of Biomedical SciencesSao PauloBrazil

Objective In this study,we assess the delivery of congenital pediatric surgical care under Brazil’s system of universal health coverage and evaluate differences in delivery between public and private *** A cross-sectional national survey of pediatric surgeons in Brazil was *** were asked which of 23 interventions identified through the Disease Control Priorities 3(Surgical Interventions for Congenital Anomalies)they perform and to report barriers faced while providing surgical *** were weighted by state and stratified by sector(public vs private).Results A sample of 352 responses was obtained and weighted to represent 1378 practicing pediatric surgeons registered in Brazil during the survey time.73%spend the majority of their time working in the public sector(‘SistemaÚnico de Saúde’and Foundation hospitals),and most of them also work in the private ***,Brazilian pediatric surgeons have the expertise to provide thoracic,abdominal,and urologic *** working mostly in the public sector were more likely to report a lack of access to essential medications(25%vs 9%,p<0.01)and a lack of access to hospital beds for surgical patients(52%vs 32%,p<0.01).Conclusions Brazilian pediatric surgeons routinely perform thoracic,abdominal,and urologic *** working in government-financed hospitals face barriers related to infrastructure,which may impact Brazilians who rely on Brazil’s universal health coverage *** that support pediatric surgeons working in the public sector may promote the workforce available to provide congenital pediatric surgical care.

关键词： pediatric survey Brazil

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Direct Electrochemical Determination of Glyphosate Herbicide Using a Screen-Printed Carbon Electrode Modified with Carbon Black and Niobium Nanoparticles

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Journal of Analysis and Testing 2023年第4期7卷 425-434页

作者： julia Oliveira Fernandes Cassiano Augusto Rolim Bernardino juliana dos Santos Fernandes Claudio Fernando Mahler Bernardo ferreira Braz Luiz Henrique Carpenter dos Santos Rodrigo JoséCorrêa Ricardo Erthal Santelli Braulio Soares Archanjo Emerson Schwingel Ribeiro Fernando Henrique Cincotto Departament of Analytical Chemistry Institute of ChemistryFederal University of Rio de JaneiroRio de Janeiro 21941-909Brazil Departament of Civil Engineering COPPEFederal University of Rio de JaneiroRio de Janeiro 21941-598Brazil National Institute of Science&Technology of Bioanalytics(INCTBio) CampinasSão Paulo 13083-862Brazil Departament of Inorganic Chemistry Institute of ChemistryFederal University of Rio de JaneiroRio de Janeiro 21941-909Brazil Unesp National Institute of Alternative Technologies for DetectionToxicological Assessment and Removal of Micropollutants and Radioactives(INCT-DATREM)AraraquaraSão Paulo 14800-060Brazil National Institute of Metrology Quality and TechnologyInmetroAv.Nossa Senhora das Graças50XerémDuque de Caxias 25250-020Brazil

Glyphosate is a herbicide that has been widely used worldwide and is used in agricultural areas to control weeds and unwanted *** sensors developed from different nanomaterials have high efficiency,excellent cost-benefit,and fast analysis time for detecting traces of environmental *** study aimed to produce an electrochemical sensor with disposable screen-printed electrodes based on carbon black modified with niobium nanoparticles to determine glyphosate in aqueous *** morphology,structure and electrochemical performance of the sensor were characterized by scanning electron microscopy,energy-dispersive X-ray spectroscopy,X-ray diffraction and cyclic *** pulse voltammetry in BR buffer solution at pH 5.0 allowed the generation of a method to quantify glyphosate concentration in a linear range of 5.90-172.30μmol/L(1.00-29.13μg/mL),with a limit of detection calculated at 3.07μmol/L(0.52μg/mL).The method efficiently quantified glyphosate in real water samples and showed no interference from K^(+),Na^(+),Ca^(2+),Mg^(2+)ions or thiamethoxam,imidacloprid and carbendazim pesticides.

关键词： Glyphosate Electrochemical sensor Carbon black Niobium nanoparticles

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Characterization of goat whey proteins and their bioactivity and toxicity assay

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Food Bioscience 2022年第2期46卷 833-843页

作者： Maria Isabel ferreira Campos Paula Perazzo de Souza Barbosa Laura Junqueira Camargo Luciano Da Silva Pinto Bianca Mataribu Catarina Serr˜ao Luis Fernando Marques-Santos Jos´e Hon´orio Lopes julia Mariano Caju de Oliveira Carlos Alberto de Almeida Gadelha Tatiane Santi-Gadelha Programa de P´os-Graduaç˜ao em Ciˆencia e Tecnologia de Alimentos Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil Departamento de Biologia Molecular Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil Centro de Desenvolvimento Tecnol´ogico Universidade Federal de PelotasRio Grande do SulBrazil Programa de P´os-Graduaç˜ao em Ciˆencias da Nutriç˜ao Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil

Goat whey is an industry-discarded dairy by-product that has interesting nutritional value and a nutrient composition with important functional potential,where proteins have a high biological value and play an important role in the organism’s ***,the aim of this study was to identify,quantify,concentrate and investigate the capacity of goat whey proteins to perform different biological activities and to evaluate their acute *** proteins were quantified and identified by Bradford,Kjehdal and SDS-PAGE *** activity was performed against Listeria monocytogenes,Salmonella spp.,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli microorganisms and showed MIC ranging from 15 to 120μg mL-1,with the highest inhibition for *** *** activity was performed against human malignant melanoma cells and their proliferation inhibition was up to 66.8%within 72 h of *** highest antioxidant capacity was obtained at concentration 2 mg that showed 29.69%of inhibition of DPPH radical *** acute toxicity test was performed using Artemia franciscana larvae in which whey proteins were able to preserve larval survival throughout ***,we can conclude that goat’s whey has proteins that can play a positive effect on health,with antimicrobial activity and without *** present study highlights the great potential of goat’s whey to be developed as a safe biopreservative or as a functional ingredient in the food industry.

关键词： Goat whey proteins Malignant cells Antimicrobial Antioxidant capacity Whey protein functionality

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Effects of Environmental Water Contamination in the Reproductive System of Mice

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Journal of Environmental Protection 2013年第7期4卷 121-125页

作者： Paulo Augusto Amador Pereira Ana julia Lichtenfels Luiz Alberto Amador Pereira Olaf Malm Paulo Hilario Nascimento Saldiva Alfesio Luis ferreira Braga Chin An Lin Environmental Epidemiology Study Group Laboratory of Experimental Air PollutionUniversity of Sao Paulo Faculty of Medical SciencesSao PauloBrazil Environmental Risk and Exposure Assessment Group Collective Health Post-Graduation ProgramCatholic University of SantosSantosBrazil Program of Environmental Biophysics and Biotechnology Institute of Biophysics Carlos Chagas FilhoFederal University of Rio de JaneiroRio de JaneiroBrazil Medical Clinics Department University of Sao Paulo Faculty of Medical SciencesSao PauloBrazil

This study investigated the effects on the reproductive system of balb-c mice exposed to water collected from different sources near to a deactivated fertilizer waste depositary. Eighty male mice were separated in four groups: Group A (mineral water);Group B (water from the water treatment station);Group C (water from Cubatao city);Group D (water from the waste depositary region). They were exposed to water since they were weaned until they reached sexual maturity, then they were coupled with females in reproductive age and after this mating time they were sacrificed. The evaluated parameters were testicle weight, sperm analysis, pregnancy rate, sex ratio of the offspring and Sertoli cell count. The analysis of the water did not show presence of pollutants in the Group “A” and Group “C” water. Group “B” showed low level of cadmium, 3.58 ± 0.50 μg/L. Group “D” showed the presence of PAH’s and high levels of lead (221 ± 16 μg/L), cadmiun (12.6 ± 1.2 μg/L) and mercury (5.3 ± 1.1 μg/L). The tests of Levene and Kolmogorov-Smirnov were employed to verify the homogeneity of the variances and the tack to the normal curve, respectively. ANOVA was used for parametric tests and Kruskall-Wallis was used for non-parametric tests, while Turkey tests were employed for multiple comparisons. There were no differences between groups in testicle weight, sperm analysis, pregnancy rate and Sertoli cell count. There was a significant reduction in sex-ratio of the offspring in Group B. This alteration cannot be explained by the cadmium levels in Group B water. In the present study we cannot associate the exposition to contaminated water from the waste depositary and reproductive alterations.

关键词： Pollution Reproduction Metals Organic Pollutants Mice

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Acute effect of moderate intensity physical exercise on postprandial hyperlipaemia of individuals with central obesity

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Health 2012年第12期4卷 1546-1550页

作者： Djeyne Silveira Wagmacker Karla Kurzendorff Souza julia Vieira da Graca Geodania da Costa Barreto Paula Caroline Souza Macêdo Tamara Felix ferreira Ana M. Ladeia Bahian School of Medicine and Public Health Science Development Foundation of Bahia Bahia Brazil College of Adventist Bahia Bahia Brazil

Introduction: High postprandial triglyceride levels and obesity are associated with coronaropathy, and influence the pathogenesis and progression of atherosclerosis. Objective: To evaluate the effect of immediate acute physical exercise on postprandial hyperlipaemia in individuals with central obesity. Methods: Study included sedentary, normolipidemic individuals aged 18 - 30 years, with waist circumference >80 in for women and >94 for men. The physical exercise was performed for 45 minutes with 55% - 60% of the heart rate reserve. Triglyceride level tests were performed after fasting, and at time intervals of 1h and 3 h after lipid overload, a week before and immediately after a session of physical exercise. Results: Thirty-six individuals were evaluated (mean age 23.74 ± 4.05 years, 88.2% women, BMI = 28.4 ± 3.4). Fasting and post-prandial triglyceride levels were similar before and after the exercise (p = 0.87). A smaller rise in triglyceride levels was observed in the 1st hour in obese individuals (5%) compared with over-weight individuals (21%) p = 0.001. Conclusion: In individuals with central obesity, moderate intensity physical exercise performed immediately before lipid overload does not reduce the hyperlipidemic peak.

关键词： Postprandial Hyperlipaemia Exercise Central Obesity

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Influence of Photoperiod over Morphometric and Hematological Parameters of Juvenile Piracanjubas （Brycon orbygnianus）

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Journal of Agricultural Science and Technology(B) 2016年第5期6卷 350-359页

作者： Monica Rodrigues ferreira Machado] Eliane Aparecida de Andrade Estefania de Souza Andrade Daniella Aparecida de Jesus Paula julia Alvarenga Oliveira Adriano Carvalho Costa Ana Paula Peconick Luis David Solis Murgas Department of Biological Science Federal University of Goias (UFG) Campus Cidade Universitaria CEP 75801-615 JataiGoias Brazil Department of Veterinary Medicine Cdmpus Universitario Federal University of Lavras (UFLA) Lavras Minas Gerais CEP3 7200-000 Brazil Department of Animal Science Federal Institute of Rio Verde (IFR V) Rio Verde Goias CEP 75901-970 Brazil

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Occurrence of Antimicrobials in River Water Samples from Rural Region of the State of Rio de Janeiro, Brazil

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Journal of Environmental Protection 2016年第2期7卷 230-241页

作者： Mychelle Alves Monteiro Bernardete Ferraz Spisso julia Rodrigues Martins Pastor dos Santos Rafaela Pinto da Costa Rosana Gomes ferreira Mararlene Ulberg Pereira Talita da Silva Miranda Bárbara Rodrigues Geraldino de Andrade Luiz Antonio d’Avila Chemistry School/Federal University of Rio de Janeiro (EQ/UFRJ) Rio de Janeiro Brazil National Institute for Quality Control in Health/Oswaldo Cruz Foundation (INCQS/FIOCRUZ) Rio de Janeiro Brazil University Centre of Barra Mansa (UBM) Barra Mansa Brazil National of Institute of Cancer (INCA) Rio de Janeiro Brazil

The occurrence of antimicrobials in the aquatic environment and drinking water has raised the question of their impact on the environment and public health. Animal production is one of the most expressive activities of Brazilian agribusiness. In order to ensure the productivity and competitiveness of the sector, the use of drugs for therapeutic and prophylactic purposes is a common practice. Due to the continuous release of antimicrobials into the environment, the aim of this study was to compare the frequency of detection of tetracyclines and sulfonamides in surface water collected from rural areas in Lidice District of Rio Claro, in the State of Rio de Janeiro, Brazil. An investigative study was conducted with 24 river water samples analyzed by high-performance liquid chromatography coupled to tandem mass spectrometry and the aim of this study was to determine residues of sulfonamides and tetracyclines based on the USEPA method 1694. The results indicated the presence of sulfamethoxazole and oxytetracycline concentrations at the ng·L-1 level. The applied method showed overall good performance with recoveries above 57%, method detection limits ≤ 7.17 ng·L-1, method quantification limits ≤ 23.90 ng·L-1 and good linearity.

关键词： Antimicrobial LC-MS/MS Surface Water Sulfonamides Tetracyclines

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Anxiety Disorder in Adolescent and the Importance of Primary Health Care to Identify This Illness

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Journal of Health Science 2018年第5期6卷 384-389页

作者： Daniel ferreira Moraes de Sousa julia de Lima Cabra Mylena Varela Santos Oliveira Lara Candida de Sousa Machado The Department of Medicine University of Rio Verde (UniRV) 75900 Brazil Medical School University of Rio Verde (UniRV) 75900 Brazil

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Goji Berry （Lycium barbarum） Extract Improves Biometric, Plasmatic and Hepatic Parameters of Rats Fed a High-Carbohydrate Diet

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Journal of Pharmacy and Pharmacology 2018年第10期6卷 877-889页

作者： Letícia Diniz Crepaldi Isabela Ramos Mariano Anna julia P. C. Trondoli Franciele Neves Moreno Silvano Piovan Maysa Formigoni Clairce L. Salgueiro-Pagadigorria Vilma A. ferreira de Godoi Márcia do Nascimento Brito Rosangela Fernandes Garcia Department of Physiological Sciences State University of Maringá Maringá PR 87020-900 Brazil Laboratory of Experimental Steatosis Department of Biochemistry State University of Maringá Maringá PR 87020-900 Brazil Laboratory of Secretion Cell Biology Department of Biotechnology Genetics and Cell Biology State University of Maringá Maringá PR 87020-900 Brazil Nucleus of Research in Natural Products Department of Biochemistry State University of Maringá Maringá PR 87020-900 Brazil

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