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Virtual reality-based cognitive-behavioural therapy for the treatment of anxiety in patients with acute myocardial infarction:a randomised clinical trial

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General Psychiatry 2024年第2期37卷 189-196页

作者： Yuanyuan Li juan peng Pingyuan Yang Jiajun Weng Yan'e Lu Jiajia Liu Shikun Xu Lihua Guan Dong Huang Qibing Wang Juying Qian Zexin Zhao Yabin Wei Junbo Ge Xiao Huang Department of Psychological Medicine Zhongshan Hospital Fudan UniversityShanghaiChina Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular DiseasesNational Clinical Research Center for Interventional MedicineShanghaiChina Department of Psychological Medicine Shanghai Geriatric Medical CenterShanghaiChina School of Nursing Peking UniversityBeijingChina Beijing Key Laboratory of Drug Dependence Research National Institute on Drug DependencePeking UniversityBeijingChina

Background The presence of mental health conditions is pervasive in patients who experienced acute myocardial infarction(AMI),significantly disrupting their recovery.Providing timely and easily accessible psychological interventions using virtual reality-based cognitive-behavioural therapy(VR-CBT)could potentially improve both acute and long-term symptoms affecting their mental health.Aims We aim to examine the effectiveness of VR-CBT on anxiety symptoms in patients with AMI who were admitted to the intensive care unit(ICU)during the acute stage of their illness.Methods In this single-blind randomised clinical trial,participants with anxiety symptoms who were admitted to the ICU due to AMI were continuously recruited from December 2022 to February 2023.Patients who were Han Chinese aged 18-75 years were randomly assigned(1:1)via block randomisation to either the VR-CBT group to receive VR-CBT in addition to standard mental health support,or the control group to receive standard mental health support only.VR-CBT consisted of four modules and was delivered at the bedside over a 1-week period.Assessments were done at baseline,immediately after treatment and at 3-month follow-up.The intention-to-treat analysis began in June 2023.The primary outcome measure was the changes in anxiety symptoms as assessed by the Hamilton Anxiety Rating Scale(HAM-A).Results Among 148 randomised participants,70 were assigned to the VR-CBT group and 78 to the control group.The 1-week VR-CBT intervention plus standard mental health support significantly reduced the anxiety symptoms compared with standard mental health support alone in terms of HAM-A scores at both post intervention(Cohen’s d=−1.27(95%confidence interval(CI):−1.64 to−0.90,p<0.001)and 3-month follow-up(Cohen’s d=−0.37(95%CI:−0.72 to−0.01,p=0.024).Of the 70 participants who received VR-CBT,62(88.6%)completed the entire intervention.Cybersickness was the main reported adverse event(n=5).Conclusions Our results indicate that VR-CBT can significantly reduce post-AMI anxiety at t

关键词： admitted behaviour treatment

Meniscus-Assisted Solution Printing Enables Cocrystallization in Poly(3-alkylthiophene)-based Blends for Field-Effect Transistors

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Chinese Journal of Polymer Science 2023年第8期41卷 1269-1276,I0009页

作者： Shu-Yin Zhu juan peng State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai 200438China

The formation of cocrystallization in two various conjugated components may endow the newly formed conjugated cocrystals with multiple functionalities and improved charge transport properties.However,compared to conjugated small molecules,this strategy is rather limitedly realized in conjugated polymers.Herein,a simple meniscus-assisted solution printing(MASP)strategy is utilized to achieve the cocrystallization in the blends of two conjugated polymers,i.e.,poly(3-hexylthiophene)(P3HT)and poly(3-octylthiophene)(P3OT),and the cocrystalline structures are correlated closely to their charge mobilities.The P3HT/P3OT blends phase separate and crystallize individually in their drop-cast thin films.When subjecting the P3HT/P3OT blended solution to MASP,the confined solvent evaporation between two nearly parallel plates triggers them to cocrystallize progressively when accelerating the moving lower plate.The cocrystallization kinetics and the changes in P3HT/P3OT molecular structures are elucidated.Finally,these different crystalline structures of P3HT/P3OT blends are applied in organic fieldeffect transistors,imparting the cocrystallization-enhanced charge transport than respective P3HT and P3OT crystal domains.Such MASP method can be extended to craft cocrystals of other conjugated polymer blends for their diverse optoelectronic applications.

关键词： Conjugated polymer blends Polythiophene Cocrystallization Charge mobility Meniscus-assisted solution printing

Interfacial behavior of a thermoelectric film bonded to a graded substrate

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Applied Mathematics and Mechanics(English Edition) 2023年第11期44卷 1853-1870页

作者： juan peng Dengke LI Zaixing HUANG Guangjian peng Peijian CHEN Shaohua CHEN School of Materials Science and Physics State Key Laboratory for Geomechanics and Deep Underground EngineeringSchool of Mechanics and Civil EngineeringChina University of Mining and TechnologyXuzhou 221116Jiangsu ProvinceChina State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China College of Mechanical Engineering Zhejiang University of TechnologyHangzhou 310014China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China Institute of Advanced Structure Technology Beijing Institute of TechnologyBeijing 100081China Beijing Key Laboratory of Lightweight Multi-functional Composite Materials and Structures Beijing Institute of TechnologyBeijing 100081China Collaborative Innovation Center of Electric Vehicles in Beijing Beijing Institute of TechnologyBeijing 100081China

To improve the thermoelectric converting performance in applications such as power generation,reutilization of heat energy,refrigeration,and ultrasensitive sensors in scramjet engines,a thermoelectric film/substrate system is widely designed and applied,whose interfacial behavior dominates the strength and service life of thermoelectric devices.Herein,a theoretical model of a thermoelectric film bonded to a graded substrate is proposed.The interfacial shear stress,the normal stress in the thermoelectric film,and the stress intensity factors affected by various material and geometric parameters are comprehensively studied.It is found that adjusting the inhomogeneity parameter of the graded substrate,thermal conductivity,and current density of the thermoelectric film can reduce the risk of interfacial failure of the thermoelectric film/graded substrate system.Selecting a stiffer and thicker thermoelectric film is advantageous to the reliability of the thermoelectric film/graded substrate system.The results should be of great guiding significance for the present and upcoming applications of thermoelectric materials in various fields.

关键词： thermoelectric film graded substrate interfacial behavior singular integral equation shear stress intensity factor

Application of intravoxel incoherent motion diffusion-weighted imaging in hepatocellular carcinoma

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World Journal of Gastroenterology 2022年第27期28卷 3334-3345页

作者： Yi Zhou Jing Zheng Cui Yang juan peng Ning Liu Lin Yang Xiao-Ming Zhang Key Laboratory of Sichuan Province Department of RadiologyMedical Research CenterThe Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina Department of Radiology People's Hospital of Deyang CityDeyang 618000Sichuan ProvinceChina Department of Radiology Panzhihua Central HospitalPanzhihua 617000Sichuan ProvinceChina Department of Radiology Sichuan Provincial People's Hospital Jinniu HospitalChengdu Jinniu District People's HospitalChengdu 610007Sichuan ProvinceChina

The morbidity and mortality of hepatocellular carcinoma(HCC)rank 6th and 4th,respectively,among malignant tumors worldwide.Traditional diffusion-weighted imaging(DWI)uses the apparent diffusion coefficient(ADC)obtained by applying the monoexponential model to reflect water molecule diffusion in active tissue;however,the value of ADC is affected by microcirculation perfusion.Using a biexponential model,intravoxel incoherent motion(IVIM)-DWI quantitatively measures information related to pure water molecule diffusion and microcirculation perfusion,thus compensating for the shortcomings of DWI.The number of studies examining the application of IVIM-DWI in patients with HCC has gradually increased over the last few years,and many results show that IVIMDWI has vital value for HCC differentiation,pathological grading,and predicting and evaluating the treatment response.The present study principally reviews the principle of IVIM-DWI and its research progress in HCC differentiation,pathological grading,predicting and evaluating the treatment response,predicting postoperative recurrence and predicting gene expression prediction.

关键词： Hepatocellular carcinoma Intravoxel incoherent motion Differentiation Pathological grading Treatment response Gene expression

Rational design of Sn_(4)P_(3)/Ti_(3)C_(2)Tx composite anode with enhanced performance for potassium-ion battery

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Rare Metals 2022年第7期41卷 2259-2267页

作者： Jie Zhao Chao-Lin Li Gang Chen Fei Ji Yi-Yong Shen juan peng Wen-Hui Wang School of Civil and Environmental Engineering Harbin Institute of TechnologyShenzhen 518055China Shenzhen Environmental Technology Group Co.Ltd. Shenzhen 518049China State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China

The potential application of high-capacity Sn_(4)P_(3)anode for potassium-ion batteries(PIBs)is hindered by the poor cycle stability mainly rooted from the huge volume changes upon cycling and low electronic conduc-tivity.To address the above issues,sandwich-like struc-tured Sn_(4)P_(3)/Ti_(3)C_(2)T_(x)was designed and synthesized as anode material for PIBs.As a result,Sn_(4)P_(3)/Ti_(3)C_(2)T_(x)pre-sents superior cycle stability(retains a capacity of 103.2 mAh·g^(-1)even after 300 cycles at 1000 mA·g^(-1))and rate capability(delivers 60.7 mAh·g^(-1)at high current density of 2000 mA·g^(-1)).The excellent electrochemical perfor-mance of sandwich-like structured Sn_(4)P_(3)/Ti_(3)C_(2)Tx is orig-inated from the synergistic effect between Sn_(4)P_(3)and Ti_(3)C_(2)T_(x),where Ti_(3)C_(2)T_(x)acts as a conductive matrix to facilitate electron transfer and buffer the volume change of Sn_(4)P_(3)particles upon cycling,while Sn_(4)P_(3)serves as pillars to prevent the collapse and stacking of Ti_(3)C_(2)T_(x)sheets.Moreover,significant capacitive contribution is demonstrated as a major contributor to the excellent rate capability.

关键词： Sn_(4)P_(3) Ti_(3)C_(2) TxAnode material Potassium-ion battery

Extracts of Portulaca oleracea promote wound healing by enhancing angiology regeneration and inhibiting iron accumulation in mice

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Chinese Herbal Medicines 2022年第2期14卷 263-272页

作者： Jinglin Guo juan peng Jing Han Ke Wang Ruijuan Si Hui Shan Xiaoying Wang Ju Zhang School of Nursing Qingdao UniversityQingdao 266071China Surgery of Traditional Chinese Medicine Second Affiliated Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300150China School of Pharmacy Qingdao UniversityQingdao 266071China

Objective:To investigate the role of Portulaca oleracea(POL)in promoting revascularization and reepithelization as well as inhibiting iron aggregation and inflammation of deep tissue pressure injury(DTPI).Methods:The hydroalcoholic extract of POL(P)and aqueous phase fraction of POL(PD)were prepared based on maceration and liquid–liquid extraction.The number of new blood vessels and VEGF-A expression level were assessed using H&E stain and Western blot on injured muscle to examine the role of POL different extracts in vascularization.The iron distribution and total elemental iron of injured muscle were detected using laser ablation inductively coupled plasma mass spectrometry(ICP-MS)and Perls’staining to determine whether POL extracts can inhibit the iron accumulation.Besides,the ability of POL extracts to promote wound healing by combining re-epithelization time,inflammation degree and collagen deposition area were comprehensively evaluated.Results:In vitro,we observed a significant increase in HUVEC cell viability,migration rate and the number of the tube after P and PD treatment(P<0.05).In vivo,administration of P and PD impacted vascularization and iron accumulation on injured tissue,evident from more new blood vessels,higher expression of VEGF-A and decreased muscle iron concentration of treatment groups compared with no-treatment groups(P<0.05).Besides,shorter re-epithelization time,reduced inflammatory infiltration and distinct collagen deposition were associated with administration of P and PD(P<0.05).Conclusion:POL extract administration groups have high-quality wound healing,which is associated with increased new blood vessels,collagen deposition and re-epithelization,along with decreased iron accumulation and inflammatory infiltration.Our results suggest that that POL extract is beneficial to repair injured muscle after ischemia–reperfusion,highlighting the potential of POL in the DTPI treatment.

关键词： deep tissue pressure injur ischemia-reperfusion Portulaca oleracea L. tissue repair wound healing

Electrochemical hydrogen-storage capacity of graphene can achieve a carbon-hydrogen atomic ratio of 1:1

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Science China Chemistry 2022年第2期65卷 318-321页

作者： Quanfeng He Lanping Zeng Lianhuan Han juan peng Matthew M.Sartin Yuan-Zhi Tan Dongping Zhan Zhong-Qun Tian State Key Laboratory of Physical Chemistry of Solid Surfaces Fujian Science&Technology Innovation Laboratory for Energy Materials of ChinaEngineering Research Center of Electrochemical Technologies of Ministry of EducationGraphene Industry and Engineering Research InstituteDepartment of ChemistryCollege of Chemistry and Chemical EngineeringDepartment of Mechanical and Electrical EngineeringSchool of Aerospace EngineeringXiamen UniversityXiamen 361005China Department of Chemistry College of Chemistry and Chemical EngineeringNingxia UniversityYinchuan 750021China

As a promising hydrogen-storage material,graphene is expected to have a theoretical capacity of 7.7 wt%,which means a carbon-hydrogen atomic ratio of 1:1.However,it has not been demonstrated yet by experiment,and the aim of the U.S.Department of Energy is to achieve 5.5 wt%in 2025.We designed a spatially-confined electrochemical system and found that the storage capacity of hydrogen adatoms on single layer graphene(SLG)is as high as 7.3 wt%,which indicates a carbon-hydrogen atomic ratio of 1:1 by considering the sp^(3) defects of SLG.First,SLG was deposited on a large-area polycrystalline platinum(Pt)foil by chemical vapor deposition(CVD);then,a micropipette with reference electrode,counter electrode and electrolyte solution inside was impacted on the SLG/Pt foil(the working electrode)to construct the spatially-confined electrochemical system.The SLG-uncovered Pt atoms act as the catalytic sites to convert protons(H^(+))to hydrogen adatoms(H_(ad)),which then spill over and are chemically adsorbed on SLG through surface diffusion during the cathodic scan.Because the electrode processes are reversible,the H_(ad) amount can be measured by the anodic stripping charge.This is the first experimental evidence for the theoretically expected hydrogen-storage capacity on graphene at ambient environment,especially by using H+rather than hydrogen gas(H_(2))as the hydrogen source,which is of significance for the practical utilization of hydrogen energy.

关键词： graphene hydrogen storage surface electrochemistry adsorption desorption spillover surface diffusion

引领动员与规则生产:农村基层协商民主建设的双重路径——基于31个案例的模糊集定性比较分析

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探索 2024年第2期 58-72页

作者：韩瑞波彭娟华中师范大学政治与国际关系学院湖北武汉430079

推进农村基层协商民主建设,是实践全过程人民民主、深化基层民主政治建设的重要内容。既有研究虽已涉及农村基层协商民主建设的影响因素分析,但以单维度的因果分析为主,无法有效呈现复杂环境下多重因素的复合影响。基于协商系统理论,通... 详细信息

推进农村基层协商民主建设,是实践全过程人民民主、深化基层民主政治建设的重要内容。既有研究虽已涉及农村基层协商民主建设的影响因素分析,但以单维度的因果分析为主,无法有效呈现复杂环境下多重因素的复合影响。基于协商系统理论,通过省思协商系统的外部环境和内部要素建构分析框架,提炼出文化引导、资源整合、主体参与、空间营造、程序规范五个变量,在全国村级议事协商创新试点单位中抽取31个案例进行模糊集定性比较分析。研究发现,农村基层协商民主实践已生成“引领动员型”和“规则生产型”两种基本路径。前者主要依托于中国共产党强大的政治动能和组织优势,借助组织嵌入、资源整合和文化培育等多重动员机制,促成政党组织力与协商实践的深度融合,衔接和整合多方主体行动,挖掘和利用乡村地方性知识,引领基层协商民主的实践细节和发展方向。后者将制度规则视为关键变量,以规范性制度文件、现代化管理方法以及信息化治理技术将议事协商的流程机制和运行规范确定下来,为协商主体行为提供具体而清晰的程序保障和积极约束,使议事协商过程和结果充分反映公共意志和公共诉求。两种协商实践路径共同发力助推协商系统的优化升级,有效推进了复杂治理和简约治理双重导向下的乡村治理现代化建设,形塑了政党特色鲜明的中国式政治民主发展之路。

关键词：基层民主协商民主协商系统政党引领乡村治理

抽滤法测定海水基免混配聚合物压裂液残渣含量

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工业水处理 2024年第7期44卷 179-184页

作者：隽鹏梁媛杜颖中海油天津化工研究设计院有限公司天津300131

针对离心法无法准确检测海水基免混配聚合物压裂液的残渣含量,提出了一种抽滤法。通过与离心法中胍胶体系压裂液破胶后残渣的粒度分离范围进行对标,选择孔径适宜的过滤纸。同时研究了不同滤样量、蒸馏水清洗量以及石油醚清洗量对检测数... 详细信息

针对离心法无法准确检测海水基免混配聚合物压裂液的残渣含量,提出了一种抽滤法。通过与离心法中胍胶体系压裂液破胶后残渣的粒度分离范围进行对标,选择孔径适宜的过滤纸。同时研究了不同滤样量、蒸馏水清洗量以及石油醚清洗量对检测数据的影响,以确定最佳的操作条件。结果表明,利用孔径为38~45μm的过滤纸、100 mL的滤样量、75 mL的蒸馏水量及100 mL的石油醚量,可得到平行性好、准确性高的检测数据,所测得的残渣质量浓度为188 mg/L,残渣得率为98.2%。此外,该方法对于1510、7130聚合物压裂液残渣含量的检测,依然具有良好的适用性。

关键词：免混配聚合物压裂液残渣含量抽滤离心

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