检索结果-南通市图书馆

BIOCELL 2016年第1期40卷 19-21页

作者： NIDIA FERRAROTTI ROSARIO MUSACCO-SEBIO CHRISTIAN SAPORITO-MAGRINA juan MANUEL acosta MARISA REPETTO Clinical Biochemistry Department Faculty of Pharmacy and BiochemistryInstitute of Biochemistry and Molecular Medicine(IBIMOL)University of Buenos Aires-CONICETBuenos AiresArgentina General and Inorganic Chemistry Faculty of Pharmacy and BiochemistryInstitute of Biochemistry and Molecular Medicine(IBIMOL)University of Buenos Aires-CONICETBuenos AiresArgentina.

The objective of this work was to study the in vivo time course of biochemical processes of oxidative damage in the brain of Sprague-Dawley rats that received an acute overload of the redox active metals iron(Fe)and copper(Cu),and the redox inactive cobalt(Co)and nickel(Ni).Oxidative stress indicators(phospholipid and protein oxidation),glutathione(GSH),antioxidant enzymes and NADPH oxidase activities,and the plasma inflam-matory cytokine(IL-6)were *** results showed that in brain oxidative mechanisms for both sets of metal are different,however in both cases are *** mechanism for Fe and Cu oxidative damage is mediated by the generation of the free radical hydroxyl(Fenton reaction and homolytic cleavage of hydroperoxides).Two events of antioxidant protection prior to oxidation of phospholipids and proteins by Fe and Cu are *** first process is the use of GSH and the second is the increased activity of the Cu,Zn-SOD and catalase *** oxidative mechanism for metal redox inactive is the consumption of GSH,NADPH oxidase activation and inflammatory response mediated by *** increased protein oxidation as a result of the inflammatory *** produced increments of phospholipid oxidation and SOD activity.

关键词： metals oxidative damage oxidative stress brain lipid peroxidation

Paroxysmal atrial fibrillation ablation:Achieving permanent pulmonary vein isolation by point-by-point radiofrequency lesions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2017年第3期9卷 230-240页

作者： Alonso Pedrote juan acosta Beatriz Jáuregui-Garrido Manuel Frutos-López Eduardo Arana-Rueda Arrhythmia Section Cardiology DepartmentVirgen del Rocío University Hospital41013 SevilleSpain

Pulmonary vein isolation by point-by-point radiofrequency catheter ablation constitutes the cornerstone of catheter ablation strategies for the treatment of atrial fibrillation. However, despite advances in pulmonary vein isolation ablation strategies, long-term success rates after ablation remain suboptimal, which highlights the need to develop techniques to achieve more durable lesions. Strategies proposed to improve the durability of pulmonary vein isolation can be divided into two groups: Those addressed to improving the quality of the lesion and those that optimize the detection of acute PV reconnection during the ablation procedure. This manuscript reviews the role and potential benefits of these techniques according to current clinical evidence.

关键词： Atrial fibrillation Pulmonary vein isolation Lesion durability Contact force Pulmonary vein reconnection

Endoscopic submucosal dissection training with pig models in a Western country

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第23期16卷 2895-2900页

作者： Adolfo Parra-Blanco María Rosa Arnau David Nicolás-Pérez Antonio Z Gimeno-García Nicolás González juan A Díaz-acosta Alejandro Jiménez Enrique Quintero Department of Gastroenterology University Hospital of the Canary Islands Ofra s/n Endoscopy Unit Department of GastroenterologyAsturias Central University HospitalCelestino Villamil s/n Research Animal Laboratory Ofra s/nLa Laguna University Department of Gastroenterology Montevideo Clinic HospitalAvda Italia s/n Research Unit University Hospital of the Canary IslandsOfra s/n

AIM:To test a strategy for endoscopic submucosal dissection(ESD) training in animal models designed to overcome the initial learning ***:ESD was attempted in ex vivo and in vivo pig *** ESD procedures were attempted in the esophagus(n=9) or the stomach(n=21).The ex vivo model was used until initial competence was *** the in vivo model,several ESD procedures were performed in up to 3 *** following variables were analyzed:specimen size,complete and en bloc resection rate,time for circumferential incision,time for submucosal dissection,total ESD duration,and ***:Complete resection was achieved in 28 cases(en bloc 27);2 could not be completed(one perforation,one technical diff iculty).The mean ± SD time for circumferential incision was 36.2±16.8 min(range:8-87 min),and the mean±SD time for submucosal dissection was 45.1±35.7 min(range:9-196 min).The mean±SD size of the resected specimens was 45.2±17.8 *** mean±SD total resection time was signif icantly increased for the gastric cases performed in the f irst half of the study(n=13) than in the second half(n=8)(98.9±62.4 min vs 61.7±17.6 min,P=0.04),although the specimen size did not ***:Training in animal models could help endoscopists overcome the learning curve before starting ESD in humans.

关键词： Endoscopic submucosal dissection Training Animal model

Effect of Domestic Wastewater as Co-Substrate on Biological Stain Wastewater Treatment Using Fungal/Bacterial Consortia in Pilot Plant and Greenhouse Reuse

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Water Resource and Protection 2018年第3期10卷 369-393页

作者： Pedroza-Camacho Lucas David Lores-acosta juan Camilo Rojas-Enríquez Johans Farid Mateus-Maldonado juan Felipe Puentes Cindy Stephanie Ramírez-Rodríguez Julio Mendez-Casallas Francy Janeth Salcedo-Reyes juan Carlos Díaz-Ariza Lucía Ana Lozano-Puentes Hair Santiago Pedroza-Rodríguez Aura Marina Programa de Biología. Departamento de Ciencias Básicas Universidad de La Salle Bogotá D.C. Colombia Facultad de Ingeniería Departamento de Ingeniería Ambiental Universidad de La Salle Bogotá D.C. Colombia Laboratorio de Microbiología Ambiental y de Suelos Grupo de Biotecnología Ambiental e Industrial Departamento de Microbiología Facultad de Ciencias Pontificia Universidad Javeriana Bogotá D.C. Colombia Laboratorio de Películas Delgadas y Nanofotonica Departamento de Física Facultad de Ciencias Pontificia Universidad Javeriana Bogotá D.C. Colombia Laboratorio Asociaciones suelo planta microorganismos (LAMIC) Grupo de Investigación en Agricultura Biológica Departamento de Biología Facultad de Ciencias Pontificia Universidad Javeriana Bogotá D.C. Colombia

In this study, a pilot wastewater treatment plant was used to evaluate the co-treatment of biological-staining residues and domestic wastewater under non-sterile conditions. A novel microbial consortia formed by Trametes versicolor, Trametes sp, Pleurotus ostreatus, Pseudomonas fluorescens, Pseudomonas azotoformans, Pseudomonas sp, Enterobacter xianfangensis and Bacillus subtillis was inoculated in an extended aeration type bio-reactor. The treatment units were operated during three consecutive cycles during a period of 147 h. After the last operating cycle, the concentrations of Chemical Oxygen Demand, Biochemical Oxygen Demand, Color Units, Total suspended solids, and the pH value were 1695 mg/L, 105 mg/L, 106 CU, 5), 1367 (CU), 566 mg/L (TSS) and 7.0 (pH) respectively. The reduction of pollutants load was related with the ratio of the two types of wastewater (3.5:0.5) combined to increase biodegradability, the concentration of fungi and bacteria used in the consortia (30 × 103 - 55 × 106 CUF/mL Total Fungi and 70 × 107 - 83 × 108 CFU/mL of Total Bacteria) and ligninolytic enzymes production, Laccase (13 - 96 U/L), MnP (9.8 - 39 U/L) and LiP (0.3 - 5.3 U/L). The post-treated effluent was used as irrigation water. Lolium perenne plants were watered during 60 days with post-treated effluent. The results of root weight showed that there are significant differences between the initial water and the effluent obtained after the operational cycles (p = 0.00470). The highest root weights (1 - 1.12 g) were found in plants irrigated with water obtained from the last treatment cycle.

关键词： Fungal/Bacterial Consortia Biological Staining and Domestic Wastewater Co-Treatment and Irrigation Reuse

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acknowledgements

Advances in Polar Science 2024年第1期35卷 142-142页

作者： Carolina acosta Hospitaleche Javier N.Gelfo Carolina acosta Hospitaleche and Javier N.Gelfo

Acknowledgement to reviewers for Vol.35 No.1 issue The editors of this special volume,along with the Editorial Board and Editorial Office of Advance in Polar Science,wish to express deep gratitude for the time invested and the meticulous revisions carried out by Enrique Bostelmann(Chile),Michael Burns(USA),Rodolfo Coria(Argentina),Jun Ebersole(USA),Jürgen Kriwet(Austria),Guillermo M.López(Argentina),James Parham(USA),juan Saad(Argentina),Leonardo Salgado(Argentina),Sergio Soto Acuña(Chile),Washington Jones(Uruguay)and seven anonymous reviewers from Argentina,China,Germany,Poland,and USA.

关键词： knowledge invested Saa

Actin levels fluctuate in the seminiferous epithelium at various stages during spermatogenesis in the rat

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

BIOCELL 2017年第2期41卷 63-65页

作者： CRISTIAN acosta MABEL FOSCOLO juan CARLOS CAVICCHIA Instituto de Histología y Embriología de Mendoza(IHEM)-CONICET Universidad Nacional de Cuyo5500MendozaArgentina

The testis is a double gland comprised of the sperm-producing seminiferous tubules and a complex endocrine *** former structures generate and release whole cells(exocrine aspect of the gland)while the latter synthesize and release androgens and related *** testis also has poorly understood paracrine *** connexions play an important role during spermatogenesis.A key molecule within these structures is β-***,the present study aims at examining the expression pattern of β-actin during the various stages of the spermatic cycle in the *** achieve this goal,we used a combination of trans-illumination assisted microdissection of seminiferous tubules,confocal immunofluorescence and Western blot *** experiments revealed that the levels of β-actin fluctuate significantly during spermatogenesis,peaking immediately after spermiation.

关键词： Beta actin Seminiferous epithelium Trans-illumination assisted microdissection

Immune challenge of mating effort:steroid hormone profile,dark ventral patch and parasite burden in relation to intrasexual competition in male Iberian red deer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrative Zoology 2020年第4期15卷 262-275页

作者： Eva DE LA PEÑA JoséMARTÍN Isabel BARJA Raúl PÉREZ-CABALLERO Isabel acosta juan CARRANZA Wildlife Research Unit University of CórdobaCórdobaSpain Department of Evolutionary Ecology National Museum of Natural Sciences(Spanish Research CouncilCSIC)MadridSpain Department of Biology Zoology UnitAutonomous University of MadridMadridSpain Biodiversity and Global Change Research Centre Autonomous University of MadridMadridSpain Parasitology and Parasitic Diseases Unit Animal Health DepartmentUniversity of CórdobaCórdobaSpain Laboratory of Malaria Immunology and Vaccinology National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaMarylandUSA

Testosterone secretion may regulate the reproductive effort and the development of sexual traits,but it may also involve costs at the immunological and metabolic ***,the evidence for this trade-off in wild populations is *** also plays an important role in mediating the reproductive and immune *** this study,we analyzed whether the endoparasite burden relates to hormonal levels(fecal testosterone and cortisol metabolites)and/or morphological sexual traits(size of the dark ventral patch,a trait that indicates reproductive effort in males)in male Iberian red *** this purpose,we sampled male red deer harvested during hunting actions in 2 types of populations in south western Spain that differed in structure,affecting the level of male–male competition for *** used coprological analyses to estimate the parasite burden mainly of gastrointestinal and bronchopulmonary nematodes and of protozoa,and assessed testosterone and cortisol metabolite levels from fecal *** found a positive relationship of host parasitation with both testosterone levels and the size of the dark ventral patch,but these relationships depended on the intensity of male–male competition in the population,being only found under the high-competition *** results are discussed under the hypothesis of the testosterone immunocompetence handicap,suggesting a cost at the immunological level,and,therefore,higher susceptibility to parasite infection in males that make a greater reproductive ***,this effect seems to be modulated by the social environment(male–male competition)that might lead to different optima in testosterone production and sexual trait development.

关键词： dark ventral patch fecal testosterone metabolites intrasexual competition male Iberian red deer parasite burden

Guillain–Barré syndrome, transverse myelitis and infectious diseases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2018年第6期15卷 547-562页

作者： Yhojan Rodríguez Manuel Rojas Yovana Pacheco Yeny acosta-Ampudia Carolina Ramírez-Santana Diana M Monsalve M Eric Gershwin juan-Manuel Anaya Center for Autoimmune Diseases Research(CREA) School of Medicine and Health SciencesUniversidad del RosarioBogotaColombia Division of Rheumatology Allergy and Clinical ImmunologyUniversity of California DavisSchool of MedicineDavisCAUSA

Guillain–Barrésyndrome(GBS)and transverse myelitis(TM)both represent immunologically mediated polyneuropathies of major clinical *** are thought to have a genetic predisposition,but as of yet no specific genetic risk loci have been clearly *** are considered autoimmune,but again the etiologies remain *** may be induced via molecular mimicry,particularly from infectious agents and vaccines,but clearly host factor and co-founding host responses will modulate disease susceptibility and natural *** is an acute inflammatory immune-mediated polyradiculoneuropathy characterized by tingling,progressive weakness,autonomic dysfunction,and *** injury specifically takes place at the myelin sheath and related Schwann-cell components in acute inflammatory demyelinating polyneuropathy,whereas in acute motor axonal neuropathy membranes on the nerve axon(the axolemma)are the primary target for immune-related *** of GBS have been reported,most frequently related to Campylobacter jejuni infection,however,other agents such as Zika Virus have been strongly *** with GBS related to infections frequently produce antibodies against human peripheral nerve *** contrast,TM is an inflammatory disorder characterized by acute or subacute motor,sensory,and autonomic spinal cord *** is interruption of ascending and descending neuroanatomical pathways on the transverse plane of the spinal cord similar to *** has been suggested to be triggered by infectious agents and molecular *** this review,we will focus on the putative role of infectious agents as triggering factors of GBS and TM.

关键词： bacterial infections disease outbreaks Guillain-Barrésyndrome transverse myelitis virus diseases Zika virus

Contrasting initial events of localized corrosion on surfaces of 2219-T42 and 6061-T6 aluminum alloys exposed in Caribbean seawater

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2019年第1期29卷 34-42页

作者： Gloria acosta Lucien VELEVA juan Luis LóPEZ D.A.LóPEZ-SAURI Applied Physics Department Research Center for Advanced Studies (CINVESTAV) Unidad Mérida Tecnológico Nacional de México Instituto Tecnológico de Mérida Departamento de Química y Bioquímica

Aluminum alloy samples, 6061-T6 and 2219-T42, were exposed to Caribbean seawater for 90 d. The fluctuations of open circuit potential, considered as electrochemical noise (EN), were used to characterize and compare initial pitting events, which appeared on their surfaces. EN analysis was carried out using the power spectral density (PSD) vs frequency. The decrease of the β exponent in PSD graphs indicated a release of spontaneous energy with the progress of pit formation in seawater. The fluctuations were associated with the breakdown and formation of new corrosion layers. The values of β exponent in PSD graphs suggest that corrosion process of AA2219-T42 alloy occurs as a persistent non-stationary process, the dynamics of which is controlled by fractional Brownian motion (fBm), while on AA6061-T6 alloy the corrosion process was dominated by stationary and weakly persistent features, with the contribution of fractional Gaussian noise (fGn). After the exposure in seawater, SEM-EDX analysis revealed insoluble intermetallic particles on the alloys, rich in Cu or Fe and irregularly distributed. The preferential dissolution of Mg and Al occurs from the S-phase (Al2CuMg) of AA2219-T42 alloy.

关键词： aluminum alloy corrosion electrochemical noise intermetallic particles seawater

Adalimumab in ulcerative colitis: Two cases of mucosal healing and clinical response at two years

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第30期15卷 3814-3816页

作者： Manuel Barreiro-de acosta Aurelio Lorenzo juan Enrique Dominguez-Muoz Department of Gastroenterology University Hospital of Santiago de CompostelaC/Choupanas/nE-15706-Santiago de CompostelaSpain

Infliximab (IFX) is currently the only biologic therapy used in the treatment of moderate-to-severe ulcerative colitis (UC). In the years to come, more biologic therapies will have a role in the management of moderate-to-severe UC. We report on two patients with steroid-dependent UC who, due to adverse reactions to IFX, have been under therapy with adalimumab for two years. Both patients received concomitant immunosuppressive treatment. Long term clinical remission and mucosal healing are described.

关键词： Adalimumab Ulcerative colitis Mucosalhealing Maintenance treatment