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Big data in healthcare:Conceptual network structure,key challenges and opportunities

Digital Communications and Networks 2023年第4期9卷 856-868页

作者： Leonardo B.Furstenaua Pedro Leivas Michele Kremer Sott Michael S.Dohan jose ricardo lopez-robles Manuel J.Cobo Nicola Luigi Bragazzi Kim-Kwang Raymond Choo Post-Graduate Program in Industrial Engineering Federal University of Rio Grande Do SulPorto Alegre90035-190Brazil University of Santa Cruz Do Sul Av.Independencia 2293Santa Cruz Do SulRSBrazil Business School Unisinos UniversityAv.Dr.Nilo Peçanha 160091330-002Porto AlegreBrazil Faculty of Business Administration Lakehead UniversityThunder BayOntarioCanada Autonomous University of Zacatecas Av.Ramon Lopez Velarde Col.CentroZacatecas98000Mexico Department of Computer Science and Artificial Intelligence Andalusian Research Institute in Data Science and Computational Intelligence(DaSCI)University of GranadaGranada 18071Spain York University ON M3J 1P3Canada Department of Information Systems and Cyber Security University of Texas at San AntonioSan AntonioTX78249USA

Big data is a concept that deals with large or complex data sets by using data analysis tools(e.g.,data mining,machine learning)to analyze information extracted from several sources *** data has attracted wide attention from academia,for example,in supporting patients and health professionals by improving the accuracy of decision-making,diagnosis and disease *** research aimed to perform a Bibliometric Performance and Network Analysis(BPNA)supported by a Scoping Review(SR)to depict the strategic themes,thematic evolution structure,main challenges and opportunities related to the concept of big data applied in the healthcare *** this goal in mind,4857 documents from the Web of Science covering the period between 2009 to June 2020 were analyzed with the support of SciMAT *** bibliometric performance showed the number of publications and citations over time,scientific productivity and the geographic distribution of publications and research *** strategic diagram yielded 20 clusters and their relative importance in terms of centrality and *** thematic evolution structure presented the most important themes and how it changes over ***,we presented the main challenges and future opportunities of big data in healthcare.

关键词： Big data Healthcare digitalization Bibliometric Strategic intelligence Co-word analysis SciMAT

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Validity of automated refraction after segmented refractive multifocal intraocular lens implantation

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International Journal of Ophthalmology(English edition) 2017年第11期10卷 1728-1733页

作者： Cesar Albarran-Diego Gonzalo Munoz Stephanie Rohrweck Satiago Garcia-Lazaro jose ricardo Albero Clinica Baviera Castellon Castellon de la Plana 12001 Spain Optics Optometry and Vision Sciences Department University of Valencia Burjassot 46100 Spain

AIM： To evaluate the clinical utility of automated refraction（AR） and keratometry（KR） compared with subjective or manifest refraction（MR） after cataract or refractive lens exchange surgery with implantation of Lentis Mplus X（Oculentis GmbH） refractive multifocal intraocular lens（IOL）.METHODS： Eighty-six eyes implanted with the Lentis Mplus X multifocal IOL were included. MR was performed in all patients followed by three consecutive AR measurements using the Topcon KR-8000 autorefractor. Assessment of repeatability of consecutive AR before and after dilation with phenylephrine 10%, and comparison of the AR and KR with MR using vector analysis were performed at 3 mo ***： Analysis showed excellent repeatability of the AR measurements. Linear regression of AR versus MR showed good correlation for sphere and spherical equivalent, whereas the correlation for astigmatism was low. The mean difference AR-MR was-1.28±0.29 diopters（D） for sphere. Astigmatism showed better correlation between KR and MR. CONCLUSION： We suggest AR sphere plus 1.25 D and the KR cylinder as the starting point for MR in eyes with a Lentis Mplus X multifocal IOL. If AR measurements are equal to MR, decentration of the IOL should be suspected.

关键词： autorefraction vector analysis agreement multifocal intraocular lenses

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Resistance and susceptibility of alfalfa （Medicago sativa L.） cultivars to the aphid Therioaphis maculata （Homoptera： Aphididae）： insect biology and cultivar evaluation

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Insect Science 2006年第1期13卷 55-60页

作者： ALEXANDRE DE ALMEIDA E SILVA ELENICE MOURO VARANDA jose ricardo BAROSELA Laboratorio de Entomologia IPEPATRO RO Brasil Departamento de Biologia Faculdade de Filosofia Ciencias e Letras de Ribeirao Preto Universidade de Sao Paulo Ribeirao Preto SP Brazil

Biology of the aphid Therioaphis maculata was studied on alfalfa （Medicago sativa L.）, including four resistant （Mesa-Sirsa, CUF101, Baker and Lahontan） and two susceptible （ARC and Caliverde） alfalfa cultivars, and one of the most cropped Brazilian cultivars, Crioula. Under controlled conditions, antibiosis （i.e., reduced longevity, fecundity and increased mortality of the aphid） was observed mainly on the resistant alfalfa cultivars, except on Lahontan. Crioula seemed to be tolerant to aphids. Present data support geographic limitation usage of cultivars, and we suggest Baker and Mesa-Sirsa as sources of antibiosis, and provide biological information of a tropical T. maculata biotype on alfalfa.

关键词： alfalfa cultivars aphid resistance susceptibility Therioaphis maculata

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Exploring research on ecotechnology through artificial intelligence and bibliometric maps

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Environmental Science and Ecotechnology 2024年第5期21卷 405-412页

作者： ricardo Ruiz-Sanchez ricardo Arencibia-Jorge Julia Tagüena jose Luis Jimenez-Andrade Humberto Carrillo-Calvet Unidad Profesional Interdisciplinaria de Ingeniería Palenque(UPIIP) Instituto Politecnico NacionalPalenqueChiapasCP 29960Mexico Complexity Sciences Center National Autonomous University of MexicoCircuito Centro Cultural s/nCoyoacan04510Mexico CityMexico Institute of Renewable Energies(IER) National Autonomous University of MexicoPriv.Xochicalco s/nCol.CentroTemixcoMorelosCP 62580Mexico Faculty of Sciences National Autonomous University of MexicoCircuito Centro Cultural s/nCoyoacan04510Mexico CityMexico

Ecotechnology,quintessential for crafting sustainable socio-environmental strategies,remains tantalizingly *** analysis,steered by the nuances of machine learning and augmented by bibliometric insights,delineates the expansive terrain of this domain,elucidates pivotal research themes and conundrums,and discerns the vanguard nations in this ***,we deftly connect our discoveries to the United Nations'2030 Sustainable Development Goals,thereby accentuating the profound societal ramifications of ecotechnology.

关键词： Ecotechnologies Bibliometrics Sustainable development goals Network analysis SOM neural networks

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Diagnosis of breast cancer by analysis of sialic acid concentrations in human saliva by surface-enhanced Raman spectroscopy of silver nanoparticles

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Nano Research 2017年第11期10卷 3662-3670页

作者： Aida Hernandez-Arteaga jose de Jeses Zermeno Nava Eleazar Samuel Kolosovas-Machuca J. Jesus Velazquez-Salazar Ekaterina Vinogradova Miguel jose-Yacaman Hugo ricardo Navarro-Contreras Coordinacion para la Innovacion y Aplicacion de la Ciencia y la Tecnologia(CIACYT) Universidad Autonoma de San Luis Potosi(A)lvaro Obregon 64 San Luis Potosi S.L.P.78000 Mexico Division de Gineco-Obstetricia Hospital Central Dr.Ignacio Morones Prieto Ave.Venustiano Carranza 2395 Zona Universitaria San Luis Potosi S.L.P.78290 Mexico Department of Physics and Astronomy University of Texas at San Antonio San Antonio TX 78249 USA

Breast cancer is the most common type of malignant tumor among women and their second leading cause of cancer-related *** most common method for screening and diagnosis is ***,two main problems have been ***,the dose of radiation received during the test prevents the method from the use on women who are 〈 40 years ***,there can be mammogram failure owing to the lack of tumor contrast with the fibrous ***,there is a need for screening methods that will help to identify high-risk *** developed a biological marker test that can help to identify *** levels of sialic acid （SA） in saliva are known to correlated with breast *** this study,we evaluated the feasibility of Raman spectroscopy as a method for quantification of SA in saliva,using citrate-reduced silver nanoparticles （cit-Ag-NPs） as a surface-enhanced Raman spectroscopy （SERS） *** of SA was accomplished by measuring its intensity in saliva and comparing it with a calibration curve of SA *** mean SA concentration in saliva was found to be significantly higher among 100 breast cancer patients （18.3 ＆#177; 9.4 mg＆#183;dL-1;mean ＆#177; SD） than among 106 healthy controls （3.5 ＆#177; 1.0 mg＆#183;dL-1）.The SERS test showed sensitivity of 94% and specificity 98% for detection of patients with breast cancer,assuming that SA concentration 〉 7 mg＆#183;dL-1 is a cutoff for positive test *** findings prove the usefulness of this SERS technique as a simple,convenient,and highly sensitive method of quantitative analysis of SA in *** simplicity of this nanotechnological test may help to substantially reduce the mortality among patients with breast cancer by providing women with a simple,noninvasive screening test that can be applied regardless of age or density of breast tissue.

关键词： breast cancer surface-enhanced Raman spectroscopy (SERS) Raman nanoparticles sialic acid

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Developing and validating a nestling photographic aging guide for cavity-nesting birds: an example with the European Bee-eater(Merops apiaster)

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Avian Research 2020年第1期11卷 57-64页

作者： Joana S.Costa Afonso D.Rocha ricardo A.Correia jose A.Alves Department of Biology&CESAM University of AveiroCampus Universitario de Santiago3810-193 AveiroPortugal Institute of Biological and Health Sciences(ICBS) Federal University of AlagoasMaceioALBrazil University of Iceland South Iceland Research CentreLindarbraut 4840 LaugarvatnIceland

Background: Accurate estimation of nestlings’ age is essential in avian demography studies as well as in population ecology and conservation. For example, it can be useful for synchronizing nest visits with events of particular interest, such as the age at which young can be safely ringed, or in choosing the best period to attain the most accurate calculation of laying or hatching ***: We constructed a photographic guide for aging European Bee-eaters(Merops apiaster) nestlings to 3-day age classes and evaluated the aging method by performing a validation exercise with several observers with no previous experience in aging bee-eater ***: The aging guide for bee-eater nestlings allowed estimating age to within 3 days with an average accuracy of 0.85. We found the optimal period for aging nestlings was between days 13-18(with accuracy between 0.94 and 0.99), during which the status of feather development was more easily distinguishable from the preceding and subsequent age classes. During the first 3 days after hatching, nestlings could also be aged with high accuracy(0.93). The small size of the nestling in relation to the eggs and the nestling’s inability to raise its head during these first days allowed for good discrimination from the subsequent age class. Between days 25 and 28, nestlings were correctly aged in only half of assignments(0.55 sensitivity) and nestlings belonging to class 7(days 7-9) were the least correctly identified(0.38 sensitivity). However, by visiting the nests at 12 days intervals it is possible to achieve the highest accuracy in age estimation with the smallest disturbance and logistic ***: This study highlighted how indirect methods and a simple protocol can be established and employed to quickly estimate nestling age in cases where handling nestlings is challenging or impossible, while minimizing disturbance in and around the nest.

关键词： Age estimation Chick development Feather growth Image guide Nest visit Plumage colour

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Intelligent collision risk detection in medium-sized cities of developing countries,using naturalistic driving:A review

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Journal of Traffic and Transportation Engineering(English Edition) 2022年第6期9卷 912-929页

作者： Juan jose Paredes Santiago Felipe Yepes ricardo Salazar-Cabrera Alvaro Pachon dela Cruz Juan Manuel Madrid Molina Telematics Engineering Research Group(GIT) Telematics DepartmentUniversidad Del CaucaPopayanColombia Information Technology and Telecommunications Research Group(12T) Universidad IcesiCaliColombia

Traffic accidents are one of the most serious problems worldwide,being one of the leading causes of death and economic loss in the ***-and middle-income countries,mainly their medium-sized cities,are among the most affected by this problem.93%of traffic accidents occur in low and middle-income countries,even though these countries have approximately 60%of the world’s *** occurs mainly because in these types of countries,especially in medium-sized cities(target context),there are no ideal conditions for driving,such as adequate road infrastructure,good condition of vehicles,and rigorous safety *** data analysis techniques including machine learning(ML)have increasingly been used to solve this *** driving(ND)can be applied as a data collection method that provides information on traffic *** commonly uses a vehicle’s kinematic data to detect high-risk driving behaviors that could cause an *** objectives of this document are to present a review of different alternatives that help in data collection and creation of intelligent solutions related to detection of possible traffic accidents,principally using ND;and to propose an intelligent collision risk detection system(ICRDS)for identification of areas with a high probability of TA in the target *** the review,it was possible to analyze and evaluate the devices,variables and algorithms that help characterize a risk event in driving,considering the target *** development of a prototype of an ICRDS for a medium-sized city in a developing country is considered viable,considering the identified components,with the aim of identifying risk events in driving,and areas of high probability of accidents in the city.

关键词： Naturalistic driving Near-crash Traffic accident Vehicle data collection

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MicroRNAs expression dynamics reveal post-transcriptional mechanisms regulating seed development in Phaseolus vulgaris L.

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Horticulture Research 2021年第1期8卷 195-211页

作者： jose ricardo Parreira Michela Cappuccio Alma Balestrazzi Pedro Fevereiro Susana de Sousa Araujo Instituto de Tecnologia Quimica e Biologica Antonio Xavier Universidade Nova de LisboaAvenida da Republica2780-157 OeirasPortugal Department of Biology and Biotechnology“L.Spallanzani” University of Paviavia Ferrata 927100 PaviaItaly InnovPlantProtect Collaborative Laboratory Estrada de Gil Vaz7351-901 ElvasPortugal Present address:Association BLC3-Technology and Innovation Campus Centre Bio R&D UnitRua Nossa Senhora da Conceicao 2Lagares da Beira3405-155 Oliveira do HospitalPortugal

The knowledge on post-transcriptional regulation mechanisms implicated in seed development(SD)is still limited,particularly in one of the most consumed grain legumes,Phaseolus vulgaris *** explore for the first time the miRNA expression dynamics in *** developing ***-two known and 39 new miRNAs were found expressed in *** developing *** of the miRNAs identified were more abundant at 10 and 40 days after anthesis,suggesting that late embryogenesis/early filling and desiccation were SD stages in which miRNA action is more *** analysis and target prediction identified targets for 77 expressed *** several known miRNAs were predicted to target HD-ZIP,ARF,SPL,and NF-Y transcription factors families,most of the predicted targets for new miRNAs encode for functional ***-targets expression profiles evidenced that these miRNAs could tune distinct seed developmental *** more accumulated at early SD stages were implicated in regulating the end of embryogenesis,postponing the seed maturation program,storage compound synthesis and *** more accumulated at late SD stages could be implicated in seed quiescence,desiccation tolerance,and longevity with still uncovered roles in *** miRNAs herein described represent novel *** resources with potential application in future biotechnological approaches to modulate the expression of genes implicated in legume seed traits with impact in horticultural production systems.

关键词： mechanisms dynamics regulating

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Sampling Error Estimation in Stratified Surveys

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Open Journal of Statistics 2013年第3期3卷 200-212页

作者： ricardo Cao jose A.Vilar Juan M.Vilar Ana K.lopez Department of Mathematics Campus de ElvinaUniversity of A CorunaA CorunaSpain

Many operations carried out by official statistical institutes use large-scale surveys obtained by stratified random sampling without replacement. Variables commonly examined in this type of surveys are binary, categorical and continuous, and hence, the estimates of interest involve estimates of proportions, totals and means. The problem of approximating the sampling relative error of this kind of estimates is studied in this paper. Some new jackknife methods are proposed and compared with plug-in and bootstrap methods. An extensive simulation study is carried out to compare the behavior of all the methods considered in this paper.

关键词： Variance Estimation Jackknife Bootstrap Stratified Sampling

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Experimental study on the wear evolution of different PVD coated tools under milling operations of LDX2101 duplex stainless steel

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Advances in Manufacturing 2023年第1期11卷 158-179页

作者： Vitor F.C.Sousa Francisco J.G.Silva ricardo Alexandre jose S.Fecheira Gustavo Pinto Andresa Baptista ISEP-School of Engineering Polytechnic of PortoRua Dr.António Bernardino de Almeida4314200–072PortoPortugal INEGI-Driving Science and Innovation Rua Dr.Roberto Frias4004200–465PortoPortugal TEandM-Technology Engineering and MaterialsS.A.Parque Industrial do TaveiroLotes 41-423045–504TaveiroPortugal

Duplex stainless steels are being used on applications that require,especially,high corrosion resistance and overall good mechanical properties,such as the naval and oil-gas exploration *** components employed in these industries are usually obtained by machining,however,these alloys have low machinability when compared to conventional stainless *** this work,a study of the wear developed when milling duplex stainless-steel,LDX 2101,is going to be presented and evaluated,employing four types of milling tools with different geometries and coatings,while studying the influence of feed rate and cutting length in the wear of these *** used have been provided with two and four flutes,as well as three different coatings,namely:TiAlN,TiAlSiN and *** cutting behavior of these tools was analyzed;data relative to the cutting forces developed during the process were obtained;and roughness measurements of the machined surfaces were *** tools were then submitted to scanning electron microscope(SEM)analysis,enabling the identification of the wear mechanisms that tools were subjected to when machining this material,furthermore,the early stages of these mechanisms were also *** this work was done with the goal of relating the machining parameters and cutting force values obtained,identifying,and discussing the wear patterns that were observed in the coating and tools after the milling tests,providing further information on the machining of these alloys.

关键词： Duplex stainless-steel Milling Tool coatings Surface roughness Wear mechanisms

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