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Multi-criteria decision making methods to address rural land allocation problems:A systematic review

International Soil and Water Conservation Research 2021年第4期9卷 490-501页

作者： Sintayehu Legesse Gebre Dirk Cattrysse Esayas Alemayehu jos van orshove. Department of Mechanical Engineering Center for Industrial ManagementTraffic&InfrastructureKU Leuven(University of Leuven)Celestijnenlaan 3003001LeuvenBelgium Department of Earth and Environmental Sciences Division of ForestNature and LandscapeKU Leuven(University of Leuven)Celestijnenlaan 200E3001LeuvenBelgium Department of Natural Resource Management Jimma UniversityJimmaEthiopia Department of Civil and Environmental Engineering JITJimma UniversityJimmaEthiopia

Land allocation has been an important issue in land use planning research *** allocation involves different multifunctional activities of maximizing environmental,economic and social ***-criteria decision making(MCDM)method is the most popular tool to optimize land allocation problems by considering decision variables,conflicting objectives,and ***,decision-makers face problems on how to optimize the land allocation while minimizing the conflicting trade-offs existing in the decision *** this review study,we aim at identifying and extracting information on MCDM methods to solve land allocation problems from English language articles published between 2000 and 2019 and indexed by four scientific literature databases(Web of Science,Science Direct,Scopus,Google scholar).To this end,we applied a systematic literature review approach,*** Preferred Reporting Items for Systematic Reviews and Meta-Analysis procedure(Moher et al.,2009),with a structured database search expression.120 articles were selected of which,after careful screening of title,keywords and abstract,69 were retained for detailed *** review study report compiles comprehensive information by classifying the papers into application area,optimization objectives,criteria used,decision techniques,publication year and study *** summary,we found that in the last two decades,the use of the MCDM method has increased,particularly in Europe and ***(analytical hierarchal process)is frequently used for multi-attribute land allocation problems with reference to ecotourism and ecosystem ***(linear programming)and SA(simulating annealing)methods are predominantly used to optimize multi-objectives complex agricultural and forest land allocation problems respectively.

关键词： Database Allocation Decision techniques PRISMA

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Simplified thermal and hygric building models： A literature review

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Frontiers of Architectural Research 2012年第4期1卷 318-325页

作者： Rick Kramer jos van Schijndel Henk Schellen Deportment of the Built Environment Eindhoven University of Technology Eindhoven 5612 AZ The Netherlonds

This paper provides a systematic literature review on simplified building modelso Questions are answered like： What kind of modelling approaches are applied？ What are their （dis）advantages？ What are important modelling aspects？ The review showed that simplified building models can be classified into neural network models （black box）, linear parametric models （black box or grey box） and lumped capacitance models （white box）. Research has mainly dealt with network topology, but more research is needed on the influence of input parameters. The review showed that particularly the modelling of the influence of sun irradiation and thermal capacitance is not performed consistently amongst researchers. Furthermore, a model with physical meaning, dealing with both temperature and relative humidity, is still lacking. Inverse modelling has been widely applied to determine models parameters. Different optimization algorithms have been used, but mainly the conventional Gaus-Newton and the newer genetic algorithms. However, the combination of algorithms to combine their strengths has not been researched. Despite all the attention for state of the art building performance simulation tools, simplified building models should not be forgotten since they have many useful applications. Further research is needed to develop a simplified hygric and thermal building model with physical meaning.

关键词： Literature review Building performancesimulation Simplified buildingmodels Inverse modelling Climate change

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Impurity analysis of gentamicin bulk samples by improved liquid chromatography-ion trap mass spectrometry

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Science China Chemistry 2011年第9期54卷 1518-1528页

作者： ZHENG Chao WANG BoChu WANG MingJuan HOOGMARTENS jos SCHEPDAEL Ann van ADAMS Erwin Bioengineering College of Chongqing University Chongqing 400030 China Katholieke Universiteit Leuven Faculteit Farmaceutische Wetenschappen Laboratorium voor Farmaceutische Analyse O&N2 PB 923 Herestraat 49 B-3000 Leuven Belgium National Institute for Control of Pharmaceutical and Biological Products Beijing 100050 China

Several gentamicin bulk samples from different origins were investigated using an LC/MS *** equipped with ion trap MS with positive ionization was performed on a Capcell Pak C18(AQ) column with the mobile phase containing 50 mM trifluoroacetic(TFA) and *** present in batches of gentamicin bulk samples were elucidated and compared according to their fragmentation *** total seventeen impurities present in samples,five impurities were not elucidated and two compounds were identified *** was observed that the impurity profiles were different in samples from different origins which indicate necessity in the quality control of gentamicin.

关键词： gentamicin liquid chromatography LC/MS impurity analysis

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A perspective on causality assessment in epigenetic research on neurodegenerative disorders

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Neural Regeneration Research 2023年第2期18卷 331-332页

作者： Philippos Koulousakis Assia Tiane Niels Hellings jos Prickaerts Daniel van den Hove Tim vanmierlo Department of Psychiatry and Neuropsychology School for Mental Health and NeuroscienceMaastricht UniversityMaastrichtThe Netherlands Department of Neuroscience Biomedical Research InstituteFaculty of Medicine and Life SciencesHasselt UniversityHasseltBelgium University MS Center(UMSC)Hasselt-Pelt HasseltBelgium Department of Immunology and Infection Biomedical Research InstituteFaculty of Medicine and Life SciencesHasselt UniversityHasseltBelgium Department of Psychiatry Psychosomatics and PsychotherapyUniversity of WuerzburgWuerzburgGermany

Epigenetics refers to herita ble and reversible processes regulating gene expression that do not involve a change to the DNA *** modifications include DNA modifications(*** methylation a nd hydroxymethyl at ion),histo... 详细信息

关键词： degenerative sequence modification

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Human liver stem/progenitor cells decrease serum bilirubin in hyperbilirubinemic Gunn rat

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World Journal of Gastroenterology 2014年第30期20卷 10553-10563页

作者： Cédric Maerckx Tatiana Tondreau Silvia Berardis jos van Pelt Mustapha Najimi Etienne Sokal Laboratory of Pediatric Hepatology and Cell Therapy Université Catholique de Louvain - Institut de Recherche Clinique et Expérimentale1200 BrusselsBelgium Katholieke Universiteit Leuven Hepatologie3000 LeuvenBelgium

AIM: To test the ability of adult-derived human liver stem/progenitor cells (ADHLSC) from large scale cultures to conjugate bilirubin in vitro and in bilirubin conjugation deficient rat.

关键词： Liver stem/progenitor cells Gunn rat Hepatocyte in vitro and in situ differentiation Uridine diphosphate-glucuronosyltransferase 1A1

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The Salt Overly Sensitive （SOS） Pathway： Established and Emerging Roles

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Molecular Plant 2013年第2期6卷 275-286页

作者： Hongtao Ji josé M. Pardo Giorgia Batelli Michael J. van Oosten Ray A. Bressan Xia Li The State Key Laboratory of Plant Cell and Chromosome Engineering Center of Agricultural Resources Research Institute of Genetics andDevelopmental Biology Chinese Academy of Sciences Shijiazhuang Hebei 050021 PR China Instituto de Recursos Naturales y Agrobiologia Consejo Superior de Investigaciones Cientificas Sevilla-41012 Spain CNR Institute of Plant Genetics (CNR-IGV) Via Universita' i33 80055 Portici Italy Department of Agricultural Engineering and Agronomy University of Naples Federico II Via Universit~ 100 80055 Portici Italy Center for Plant Environmental Stress Physiology Purdue University West Lafayette IN 47907-2010 USA Department Biological Sciences King Abdulaziz University Kingdom of Saudi Arabia

Soil salinity is a growing problem around the world with special relevance in farmlands. The ability to sense and respond to environmental stimuli is among the most fundamental processes that enable plants to survive. At the cellular level, the Salt Overly Sensitive （SOS） signaling pathway that comprises SOS3, SOS2, and SOS1 has been proposed to mediate cellular signaling under salt stress, to maintain ion homeostasis. Less well known is how cellularly heterog- enous organs couple the salt signals to homeostasis maintenance of different types of cells and to appropriate growth of the entire organ and plant. Recent evidence strongly indicates that different regulatory mechanisms are adopted by roots and shoots in response to salt stress. Several reports have stated that, in roots, the SOS proteins may have novel roles in addition to their functions in sodium homeostasis. SOS3 plays a critical role in plastic development of lateral roots through modulation of auxin gradients and maxima in roots under mild salt conditions. The SOS proteins also play a role in the dynamics of cytoskeleton under stress. These results imply a high complexity of the regulatory networks involved in plant response to salinity. This review focuses on the emerging complexity of the SOS signaling and SOS protein functions, and highlights recent understanding on how the SOS proteins contribute to different responses to salt stress besides ion homeostasis.

关键词： auxin ion homeostasis root system architecture salt stress the SOS signaling pathway.

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Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery

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World Journal of Gastroenterology 2008年第45期14卷 6960-6969页

作者： Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen Department of Surgery VU University Medical Center Amsterdam Amsterdam and Medical Center Alkmaar Department of Surgery VU University Medical Center Amsterdam Department of Surgery Catharina Hospital Department of Clinical Chemistry VU University Medical Center Amsterdam Department of Epidemiology and Biostatistics VU University Medical Center Amsterdam Department of Surgery Medical Center Alkmaar

AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal ***: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after ***: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery.

关键词： Antioxidants Critical illness Enteral nutrition Oxidative stress Surgery Upper gastrointestinal tract

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Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

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Cellular & Molecular Immunology 2021年第6期18卷 1528-1544页

作者： Renato G.S.Chirivi jos W.Gvan Rosmalen Maarten van der Linden Maximilien Euler Gonny Schmets Galina Bogatkevich Konstantinos Kambas Jonas Hahn Quinte Braster Oliver Soehnlein Markus H.Hoffmann Helmuth H.Gvan Es jos M.H.Raats ModiQuest B.V. OssThe Netherlands Citryll B.V. OssThe Netherlands Department of Internal Medicine 3-Rheumatology and Immunology University Hospital ErlangenFriedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital ErlangenErlangenGermany Department of Medicine Division of Rheumatology and ImmunologyMedical University of South CarolinaCharlestonSCUSA Laboratory of Molecular Hematology Democritus University of ThraceAlexandroupoliGreece Institute for Cardiovascular Prevention(IPEK) Ludwig-Maximilians-University MunichMunichGermany German Center for Cardiovascular Research(DZHK) Partner Site Munich Heart AllianceMunichGermany Department of Physiology and Pharmacology Karolinska InstitutetStockholmSweden

Excessive release of neutrophil extracellular traps(NETs)is associated with disease severity and contributes to tissue injury,followed by severe organ *** or genetic inhibition of NET release reduces pathology in multiple inflammatory disease models,indicating that NETs are potential therapeutic ***,we demonstrate using a preclinical basket approach that our therapeutic anti-citrullinated protein antibody(tACPA)has broad therapeutic *** with tACPA prevents disease symptoms in various mouse models with plausible NET-mediated pathology,including inflammatory arthritis(IA),pulmonary fibrosis,inflammatory bowel disease and *** show that citrulline residues in the N-termini of histones 2A and 4 are specific targets for therapeutic intervention,whereas antibodies against other N-terminal post-translational histone modifications have no therapeutic *** citrullinated histones are generated during NET release,we investigated the ability of tACPA to inhibit NET *** suppressed NET release from human neutrophils triggered with physiologically relevant human disease-related ***,tACPA diminished NET release and potentially initiated NET uptake by macrophages in vivo,which was associated with reduced tissue damage in the joints of a chronic arthritis mouse model of *** our knowledge,we are the first to describe an antibody with NET-inhibiting properties and thereby propose tACPA as a drug candidate for NET-mediated inflammatory diseases,as it eliminates the noxious triggers that lead to continued inflammation and tissue damage in a multidimensional manner.

关键词： Neutrophil Extracellular Traps Autoimmunity Citrullination Therapeutic Antibody NET inhibition

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Drought and conflicts at the local level: Establishing a water sharing mechanism for the summer-autumn rice production in Central Vietnam

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International Soil and Water Conservation Research 2019年第4期7卷 362-375页

作者： Chuong van Huynh Catharien Terwisscha van Scheltinga Ty Huu Pham Non Quoc Duong Phuong Thi Tran Linh Hoang Khanh Nguyen Tung Gia Pham Ngoc Bich Nguyen jos Timmerman Hue University Viet Nam Climate Change and Adaptive Land and Water Management Group Wageningen Environmental ResearchNetherlands University of Agriculture and Forestry Hue UniversityViet Nam

In recent years,water for agricultural production gradually became a significant challenge in the context of climate change in *** solutions are required,which consider the use of resources for both human needs and ecology,and that account for the equitable distribution and the livelihood of the farmers now and in the *** particular,the farmers in the province of Quang Nam faring water shortage in the cultivation of paddy in the summer-autumn *** arise regarding the sharing of the water between the farmers,the drinking water company and the hydropower *** the context of climate change,the water shortage is expected to increase in the *** article presents the results of participatory action research (PAR) approach to develop a local level mechanism for water sharing,in which stakeholders actively *** sharing mechanism was developed,envisioning a sustainable solution for inclusive water *** mechanism was successfully implemented in two cases,one at commune level (Tho stream) and one at the district level (Mo stream).The participatory approach proved to be successful in setting up a broadly acceptable mechanism that will need to be further incorporated in the institutional set-up.

关键词： Adaptation Agriculture Climate change Governance Rice production Water sharing

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The Effect of Micro Air Movement on the Heat and Moisture Characteristics of Building Constructions

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Journal of Civil Engineering and Architecture 2010年第10期4卷 9-15页

作者： A.W.M. （jos） van Schijndel Eindhoven University of Technology Eindhoven Netherlands

The research focuses on the effect of air movement through building constructions. Although the typical air movement inside building constructions is quite small （velocity is of order -10-5 m/s）, this research shows the impact on the heat and moisture characteristics. The paper presents a case study on the modeling and simulation of 2D heat and moisture transport with and without air movement for a building construction using a state-of-art multiphysics FEM software tool. Most other heat and moisture related models don＇t include airflow or use a steady airflow through the construction during the simulation period. However, in this model, the wind induced pressure is dynamic and thus also the airflow through the construction is dynamic. For this particular case study, the results indicate that at the intemal surface, the vapor pressure is almost not influenced by both the 2D effect and the wind speed. The temperatures at the inner surface are mostly influenced by the 2D effect. Only at wind pressure differences above 30 Pa, the airflow has a significant effect. At the extemal surface, the temperatttres are not influenced by both the 2D effect and the wind speed. However, the vapor pressure seems to be quite dependent on the wind induced pressure. Overall it is concluded that air movement through building materials seems to have a significant impact on the heat and moisture characteristics. In order to verify this statement and validate the models, new in-depth experiments including air flow through materials are recommended.

关键词： Construction heat moisture transfer air movement modeling.

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