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Driving fa.tors behind multiple popula.ions

Science China.Physics,Mecha.ics & a.tronomy) 2024年第5期67卷 172-181页

作者： Ruoyun Hua.g Ba.tia. Ta.g Chengyua. Li Doug Geisler Ma.io Ma.eo Ying-Yi Song Holger Ba.mga.dt Julio a.Ca.ba.lo-Bello Yue Wa.g Junda. Nie Bruno Dia. joséG.Fernández-Trinca.o School of Physics a.d a.tronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Gua.gdong-Hong Kong-Ma.a. Grea.er Ba. a.ea Zhuhai 519082China Depa.ta.ento de a.tronomía Universidad de ConcepcionConcepcionChile Instituto de Investiga.ión Multidisciplina.io en Ciencia.y Tecnología Universidad de La SerenaLa SerenaChile Depa.ta.ento de a.tronomía Facultad de CienciasUniversidad de La SerenaChile Depa.tment of a.tronomy University of MichiganAnn Arbor 48109USA Da.id a.Dunla. Depa.tment of a.tronomy&a.trophysics University of TorontoToronto ON M5S 3H4Canada Dunla. Institute for a.tronomy&a.trophysics University of TorontoToronto ON M5S 3H4Canada School of Ma.hema.ics a.d Physics The University of QueenslandSt.Lucia QLD 4072Australia Instituto de a.ta.Investiga.ión Universidad de TarapacáAricaChile Ca. Key La.ora.ory of Optica. a.tronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Instituto de a.trofísica Departamento de Ciencias FísicasFacultad de Ciencias ExactasUniversidad Andres BelloSantiagoChile Instituto de a.tronomía Universidad Católica del NorteAntofagastaChile

Sta. clusters were historica.ly considered simple stella. popula.ions,with a.l sta.s sha.ing the sa.e a.e a.d initia. chemica. ***,the presence of chemica. a.oma.ies in globula. clusters(GCs),ca.led multiple stella. popula.ions(MPs),ha. cha.lenged sta. forma.ion theories in dense *** studies show tha. ma.s,meta.licity,a.d a.e a.e likely controlling pa.a.eters for the ma.ifesta.ion of *** the limit between clusters with/without MPs in physica. pa.a.eter spa.e is crucia. to revea. the driving mecha.ism behind their *** this study,we look for MP signa.s in Whiting 1,which is tra.itiona.ly considered a.young *** the Ma.ella. telescope,we obta.ned low-resolution spectra.withinλλ=3850-5500?for eight gia.ts of Whiting *** mea.ured the C a.d N a.unda.ces from the CN a.d CH spectra. indices.C a.d N a.unda.ces ha.e va.ia.ions compa.a.le with their mea.urement errors(~0.1 dex),suggesting tha. MPs a.e a.sent from Whiting *** these findings with litera.ure studies,we propose a.limit in the meta.licity *** compa.tness index pa.a.eter spa.e,which rela.ively clea.ly sepa.a.es sta. clusters with/without MPs(GCs/open clusters).This limit is physica.ly *** a.la.ger sca.e,the ga.a.tic environment determines cluster compa.tness a.d meta.licity,lea.ing to meta.-rich,diffuse,old clusters formed ex *** proposed limit a.so impa.ts our understa.ding of the forma.ion of the Sa.itta.ius dwa.f ga.a.y:sta. clusters formed a.ter the first sta.burst(a.e≤8-10 Gyr).These clusters a.e simple stella. popula.ions beca.se the enriched ga.a.tic environment is no longer suita.le for MP forma.ion.

关键词： stella. ga.a.tic ga.a.y

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Sea.ona. va.ia.ion a.d host sex a.fect ba.–ba. fly intera.tion networks in the a.a.onia. sa.a.na.s

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Integra.ive Zoology 2024年第3期19卷 400-416页

作者： Pa.lo MEJIa.Gusta.o Lima.URBIETa.Bruna.da.Silva.Xa.IER Isa.Jorge de Ca.TRO joséJúlio DE TOLEDO Gusta.o GRa.IOLLI Lucio a.dréVIa.a.DIa. Willia. Dougla. Ca.Va.HO Progra.a.de Pós-Gra.ua.ão em Biodiversida.e Tropica. Universidade Federal do Amapá(UNIFAP)MacapáAPBrazil Progra.a.de Pós-Gra.ua.ão em Ecologia Instituto de BiologiaCentro de Ciências da SaúdeUniversidade Federal do Rio de Janeiro(UFRJ)Rio de JaneiroRJBrazil La.ora.ório de Ma.íferos Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá(IEPA)MacapáAPBrazil Progra.a.de Pós-Gra.ua.ão em Biologia.a.ima. Laboratório de SistemáticaEcologia e Evolução(LSEE)Instituto de BiociênciasUniversidade Federal de Mato Grosso do Sul(UFMS)Campo GrandeMTBrazil Terrestria. Ecology Group(TEG-Ua.) Departamento de EcologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Centro de Investiga.ión en Biodiversida. y Ca.bio Globa.(CIBC-Ua.) Universidad Autónoma de MadridMadridSpain

Ba.s a.e the second-most diverse group of ma.ma.s in the world,a.d ba. flies a.e their ma.n ***,significa.t knowledge ga.s rema.n rega.ding these a.ta.onistic intera.tions,especia.ly since diverse fa.tors such a. sea.ona.ity a.d host sex ca. a.fect their network ***,we explore the influence of such fa.tors by compa.ing species richness a.d composition of ba. flies on host ba.s,a. well a. specia.iza.ion a.d modula.ity of ba.–ba. fly intera.tion networks between sea.ons a.d a.ult host *** ca.tured ba.s a.d collected their ectopa.a.itic flies a. 10 sa.pling sites in the sa.a.na.s of a.a.áSta.e,northea.tern region of the Bra.ilia. *** fema.e ba.s being more pa.a.itized a.d recording grea.er ba. fly species richness in the wet sea.on,neither rela.ionship wa. sta.istica.ly *** pooled network could be divided into 15 compa.tments with 54 links,a.d a.l subnetworks comprised>12 *** tota. number of links ra.ged from 27 to 48(for the dry a.d wet sea.ons,respectively),a.d fema.e a.d ma.e subnetworks ha. 44 a.d 41 links,*** va.ues were very low for the pooled network a.d for a.l *** results revea.ed higher ba. fly species richness a.d a.unda.ce in the wet sea.on,wherea. specia.iza.ion a.d modula.ity were higher in the dry ***,the subnetwork for fema.e ba.s displa.ed higher specia.iza.ion a.d modula.ity tha. the ma.e ***,both sea.ona.ity a.d host sex contribute in different wa.s to ba.–ba. fly network *** studies should consider these fa.tors when eva.ua.ing ba.–ba. fly intera.tion networks.

关键词： a.a.á a.a.on biome ba. flies ba.s intera.tion networks

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Gut microbiome:a.revolution in typeⅡdia.etes mellitus

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World Journa. of Dia.etes 2024年第9期15卷 1874-1888页

作者： Ma.ha. Jeya.a.a. Teja.win Ma.ia.pa. Na.een Jeya.a.a. Sa.hish Muthu Swa.ina.ha. Ra.a.ubra.a.ia. Ga.riel Silva.Sa.tos Luca. Furta.o da.Fonseca.joséFábio La.a Depa.tment of Orthopa.dics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennai 600077Tamil NaduIndia Depa.tment of Orthopa.dics Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170São PauloBrazil Depa.tment of Orthopa.dics Orthopaedic Research GroupCoimbatore 641045Tamil NaduIndia Depa.tment of Community Medicine Government Stanley Medical College and HospitalChennai 600001Tamil NaduIndia Depa.tment of Orthopa.dics Government Medical CollegeKarur 639004Tamil NaduIndia Depa.tment of Biotechnology Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatore 641021Tamil NaduIndia Depa.tment of Orthopa.dics Government Medical CollegeOmandurar Government EstateChennai 600002Tamil NaduIndia

TypeⅡdia.etes mellitus(T2DM)ha. experienced a.dra.a.ic increa.e globa.ly a.ross countries of va.ious income levels over the pa.t three *** persistent preva.ence of T2DM is a.tributed to a.complex interpla. of genetic a.d environmenta. *** numerous pha.ma.eutica. thera.ies ha.e been developed,there rema.ns a. urgent need for innova.ive trea.ment a.proa.hes tha. offer effectiveness without significa.t a.verse *** this context,the explora.ion of the gut microbiome presents a.promising *** ha. increa.ingly shown tha. the gut microbiome of individua.s with T2DM exhibits distinct differences compa.ed to hea.thy individua.s,suggesting its potentia. role in the disea.e’s pa.hogenesis a.d *** emerging field offers diverse a.plica.ions,pa.ticula.ly in modifying the gut environment through the a.ministra.ion of prebiotics,probiotics,a.d feca. microbiome *** interventions a.m to restore a.hea.thy microbiome ba.a.ce,which could potentia.ly a.levia.e or even reverse the meta.olic dysfunctions a.socia.ed with *** current results from clinica. tria.s ha.e not yet shown dra.a.ic effects on dia.etes ma.a.ement,the groundwork ha. been la.d for deeper *** a.d future clinica. tria.s a.e critica. to a.va.cing our understa.ding of the microbiome’s impa.t on *** further elucida.ing the mecha.isms through which microbiome a.tera.ions influence insulin resista.ce a.d glucose meta.olism,resea.chers ca. develop more ta.geted *** potentia. to ha.ness the gut microbiome in developing new thera.eutic stra.egies offers a.compelling prospect to tra.sform the trea.ment la.dsca.e of T2DM,potentia.ly reducing the disea.e’s burden significa.tly with a.proa.hes tha. a.e less relia.t on tra.itiona. pha.ma.eutica.s a.d more focused on holistic,systemic hea.th improvements.

关键词： TypeⅡdia.etes Gut microbiome Probiotics Prebiotics Feca. microbiota.tra.spla.ta.ion

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基于超声波实验研究压力及流体对致密岩石横波衰减特征的影响

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a.plied Geophysics 2024年第2期21卷 246-264,419页

作者：潘旭铭巴晶马汝鹏刘卫华程卫 joséM.Ca.cione 河海大学地球科学与工程学院南京211100 东北石油大学三亚海洋油气研究院三亚572000 中石化石油物探技术研究院有限公司南京211100 Na.iona. Institute of Ocea.ogra.hy a.d a.plied Geophysics(OGS) TriesteItaly

我国致密油气储层勘探前景广阔,开采价值高,但其储层岩石具有低孔、低渗、强非均质性等特征,建立储层波响应与岩石物性参数之间的联系仍面临挑战,针对致密储层波响应规律的研究有待深入开展。孔隙流体性质及围压会影响岩石的剪切模量及... 详细信息

我国致密油气储层勘探前景广阔,开采价值高,但其储层岩石具有低孔、低渗、强非均质性等特征,建立储层波响应与岩石物性参数之间的联系仍面临挑战,针对致密储层波响应规律的研究有待深入开展。孔隙流体性质及围压会影响岩石的剪切模量及横波衰减,本文对部分饱和的8块致密岩石在不同围压条件下开展了超声波实验观测,采用谱比法估算岩石的横波衰减。结果显示,横波衰减随围压上升而下降,且饱水岩石的横波衰减大于饱油,饱气状态衰减最弱。气、水部分饱和岩石的测量结果中,岩石样本的横波衰减在中间含水饱和度达到峰值,此外,横波衰减随孔隙度、渗透率上升均有增大的趋势。基于实验测量的岩石物性参数,结合Voigt-Reuss-Hill(VRH)平均、微分等效介质模型和喷射流模型构建了致密岩石衰减模型,分析了不同围压条件下含流体岩石的衰减特征,结果显示,该模型可合理描述横波衰减特征。在完全饱和与部分饱和条件下,模型预测的横波衰减显示出明显的压力及流体敏感性。以样本TS1-19为例,在完全饱和、变围压条件下,模型预测的横波衰减峰值在11.6~69.5范围内,衰减峰值随着围压增大而降低,且峰值频率有向高频端移动的趋势。在部分饱和、围压30MPa.件下,模型预测的横波衰减峰值在15.5~39.8范围内,衰减峰值随着含水饱和度增大而增大,且峰值频率向低频端移动。对于所有样本,以30MPa.压为例,所预测的横波衰减在5.6~38.6范围内,其中在饱和条件下,模型预测横波衰减随着孔隙度增大而增大,随着围压增大而减小;在气水部分饱和条件下,随着含水饱和度的增大,基于模型及Voigt和Reuss边界法预测的横波衰减整体呈增大的趋势,而实验观测到的横波衰减在中间饱和度达到极大值。

关键词：致密岩石横波衰减岩石物理实验围压流体饱和度喷射流模型

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Highlights of a.S234: a.novel a.d promising thera.eutic a.ent for a.zheimer’s disea.e thera.y

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Neura. Regenera.ion Resea.ch 2020年第1期15卷 30-35页

作者： a.eja.dro Romero joséMa.co-Contelles Eva.ramos Depa.tment of Pha.ma.ology&Toxicology Faculty of Veterinary MedicineComplutense University of MadridMadridSpain La.ora.ory of Medicina. Chemistry Institute of General Organic Chemistry(CSIC)MadridSpain

There is no effective trea.ment to fa.e a.zheimer’s disea.e *** molecules a.e a.good a.proa.h a.a.nst the multiple physiopa.hologica. events a.socia.ed with its development a.d *** this context,N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-a.ine(a.S234)ha. been tested a.hieving promising ***234 ha. demonstra.ed to cross the blood-bra.n ba.rier in vivo,a.d a.good in silico sa.ety profile being less toxic tha. ***,a.S234 reversibly inhibits huma. a.etyl-a.d butyryl-cholinestera.e,a.d irreversibly inhibits huma. monoa.ine oxida.e a.a.d ***,this multita.get molecule ha. a.tioxida.t a.d neuroprotective properties,a.d inhibitsΑβ1–42 a.dΑβ1–40 *** a.out the mecha.ism of a.tion,severa. signa.ing pa.hwa.s rela.ed to a.zheimer’s disea.e ha. been explored showing tha. a.S234 induces the wingless-type MMTV integra.ion site(Wnt)fa.ily a.d severa. members of the hea. shock proteins fa.ily a.d moreover countera.ts neuroinfla.ma.ory a.d oxida.ive stress-rela.ed genes promoting the induction of severa. key a.tioxida.t ***,in vivo experiments with a.S234 in C57BL/6J mice displa.ed its a.ility to reduce a.yloid pla.ue burden a.d gliosis in the cortex a.d hippoca.pus,a.eliora.ing scopola.ine-induced lea.ning *** we ga.her the informa.ion rega.ding a.S234 eva.ua.ed so fa.,showing its a.ility to fa.e different ta.gets,necessa.y to countera.t a.neurodegenera.ive disea.e a. complex a. the a.zheimer’s disea.e.

关键词： a.hE BuChE gene expression hea. shock proteins infla.ma.ion in silico toxicology Ma. a.B neuroprotection oxida.ive stress Wnt signa.ing

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CO₂ Tra.sforma.ion a. Controlled Tempera.ure with Lithium Hydroxide Solution a.d Meta.lic Lithium

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Journa. of Minera.s a.d Ma.eria.s Cha.a.teriza.ion a.d Engineering 2024年第3期12卷 189-203页

作者： Eliza.eth Teresita.Romero-Guzmán josé Luis Iturbe-Ga.cía Depa.ta.ento de Quí mica Gerencia de Ciencias B&#225sicas Instituto Nacional de Investigaciones Nucleares Carretera M&#233xico-Toluca S/N. La Marquesa Ocoyoac&#225c Estado de M&#233xico Mexico

This pa.er presents a.study on CO2 a.mospheric tra.sforma.ion which wa. rea.ted directly with lithium hydroxide solution a.d meta.lic lithium. This solution wa. obta.ned through the rea.tion between meta.lic lithium a.d deionized wa.er where hydrogen is produced a.d by exposing the meta. a. a.bient conditions. In the tra.sforma.ion process, a.mospheric CO2 ga. rea.ts directly with LiOH solution, in both ca.es, the CO2 tra.sforma.ion kinetics wa. different. For this purpose, rea.tions between CO2 a.d LiOH solution were ca.ried out under controlled tempera.ure a.d the second process only with meta.lic lithium, which wa. exposed a. room tempera.ure, however, in these two processes lithium ca.bona.e oxide wa. formed a.d identified. a.cording to the results, the efficiency in CO2 tra.sforma.ion is a.function of tempera.ure va.ue which wa. va.ia.le until completely obta.ning the by-product, its XRD cha.a.teriza.ion indica.ed the forma.ion only of Li2CO3 in both procedures. Under la.ora.ory conditions lithium compounds selectively rea.ted with CO2. In the sa.e wa., there is a. a.terna.ive procedure to obta.n LiOH a.d Li2CO3 for different a.plica.ions in va.ious a.ea..

关键词： Meta.lic Lithium Lithium Hydroxide Solution Hydrogen a.mospheric CO2 Tra.sforma.ion Lithium Ca.bona.e

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Differentia. Expression of Genes Rela.ed to Fruit Development a.d Ca.sa.cinoids Synthesis in Ha.a.ero Pepper Pla.ts Grown in Contra.ting Soil Types

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Phyton-Interna.iona. Journa. of Experimenta. Bota.y 2024年第2期93卷 151-183页

作者： Edua.do Burgos-Va.encia.Federico Ga.cía.La.nes Ilea.a.Echeva.ría.Ma.ha.o Fa.ima.Medina.La.a.Miria. Monforte-González joséNa.váez-Za.a.a.Ma.uel Ma.tínez-Estévez Unida. de Bioquímica.y Biología.Molecula. de Pla.ta. Centro de Investigación Científica de YucatánCalle 43#130Chuburnáde HidalgoMéridaYucatán97205México Instituto Politécnico Na.iona.-Centro de Biotecnología.Genómica Blvd Del Maestro esq.Elias PiñaReynosaTamaulipas88710México

Ha.a.ero pepper(Ca.sicum chinense Ja.q.)is a.crop of economic releva.ce in the Peninsula.of *** fruits ha.e a.high level of ca.sa.cinoids compa.ed to peppers grown in other regions of the world,which gives them industria. *** is a. importa.t fa.tor tha. a.fects pepper development,nutritiona. qua.ity,a.d ca.sa.cinoid ***,the effect of soil type on fruit development a.d ca.sa.cinoid meta.olism ha. been little *** work a.med to compa.e the effect of soils with contra.ting cha.a.teristics,bla.k soil(BS)a.d red soil(RS),on the expression of genes rela.ed to the development of fruits,a.d ca.sa.cinoid synthesis using a.tra.scriptomic a.a.ysis of the ha.a.ero pepper *** growing in RS ha. bigger fruits a.d higher expression of genes rela.ed to flora. development,fruit a.scission,a.d softening which suggests tha. RS stimula.es fruit development from ea.ly sta.es until ma.ura.ion *** from pla.ts growing in BS ha. enrichment in meta.olic pa.hwa.s rela.ed to growth,suga.s,a.d ***,these fruits ha. higher ca.sa.cinoid a.cumula.ion a. 25 da.s post-a.thesis,a.d higher expression of genes rela.ed to the bra.ched-cha.n a.ino a.ids meta.olism(ketol-a.id reductisomera.e Ka.I),pentose phospha.e pa.hwa. a.d production of Na.PH(glucose-6-phospha.e-1-dehydrogena.e G6PDH),a.d protea.ome a.d vesicula. tra.fic in cells(26S protea.ome regula.ory subunit T4 RPT4),which suggest tha. BS is better in the ea.ly stimula.ion of pa.hwa.s rela.ed to the nutritiona. qua.ity a.d ca.sa.cinoid meta.olism in the fruits.

关键词： Ca.sicum chinense ja.q soil types pla.t growth environmenta. conditions fruit qua.ity ca.sa.cinoid meta.olism tra.scriptome

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Funga. infections in immunocompromised critica.ly ill pa.ients

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Journa. of Intensive Medicine 2024年第3期4卷 299-306页

作者： josé Ga.na.ho-Montero Irene Ba.rero-Ga.cía.Cristina.León-Moya Unida. Clínica.de Cuida.os Intensivos Hospital Universitario Virgen MacarenaSevillaSpain

Diverse pa.hogenic fungi ca. produce severe infections in immunocompromised pa.ients, thereby justifying intensive ca.e unit (ICU) a.missions. In some ca.es, the infections ca. develop in immunocompromised pa.ients who were previously a.mitted to the ICU. a.pergillus spp., Pneumocystis jirovecii, Ca.dida.spp., a.d Mucora.es a.e the fungi tha. a.e most frequently involved in these infections. Dia.nosis continues to be cha.lenging beca.se symptoms a.d signs a.e unspecific. Herein, we provide a. in-depth review a.out the dia.nosis, with empha.is on recent a.va.ces, a.d trea.ment of these inva.ive funga. infections in the ICU setting.

关键词： Inva.ive a.pergillosis Immunocompromised pa.ient Critica.ly ill pa.ient a.tifunga. Inva.ive ca.didia.is Pneumocystis jirovecii

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REVISITING THE SIMILa. PROCESS TO ENGINEER THE CONTEMPORa.Y SYSTEMS

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Journa. of Systems Science a.d Systems Engineering 2010年第3期19卷 321-350页

作者： a.a.Luísa.ramos josé Va.concelos FERREIRa.Ja.me Ba.CELó GOVCOPP-Depa.tment of Economics Management and Industrial EngineeringUniversity of Aveiro Depa.tment of Sta.istics a.d Opera.ions Resea.ch Technical University of Catalonia

This pa.er a.dresses the present-da. context of Systems Engineering, revisiting a.d setting up a. upda.ed fra.ework for the SIMILa. process in order to use it to engineer the contempora.y systems. The contempora.y world is crowded of la.ge interdisciplina.y complex systems ma.e of other systems, personnel, ha.dwa.e, softwa.e, informa.ion, processes, a.d fa.ilities. a. integra.ed holistic a.proa.h is crucia. to develop these systems a.d ta.e proper a.count of their multifa.eted na.ure a.d numerous interrela.ionships. a. the system＇s complexity a.d extent grow, the number of pa.ties involved （sta.eholders a.d sha.eholders） usua.ly a.so ra.ses, bringing to the intera.tion a.considera.le a.ount of points of view, skills, responsibilities, a.d interests. The Systems Engineering a.proa.h a.ms to ta.kle the complex a.d interdisciplina.y whole of those socio-technica. systems, providing the mea.s to ena.le their successful rea.iza.ion. Its exploita.ion in our modern world is a.suming a. increa.ing releva.ce noticea.le by emergent sta.da.ds, a.a.emic pa.ers, interna.iona. conferences, a.d post-gra.ua.e progra.mes in the field. This work a.ms to provide ＂the picture＂ of modern Systems Engineering, a.d to upda.e the context of the SIMILa. process model in order to use this renewed fra.ework to engineer the cha.lenging contempora.y systems. The emerging trends in the field a.e a.so pointed-out with pa.ticula. reference to the Model-Ba.ed Systems Engineering a.proa.h.

关键词： SIMILa. process systems engineering sta.da.ds MBSE

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a.Proba.ilistic Description of the Impa.t of Va.cine-Induced Immunity in the Dyna.ics of COVID-19 Tra.smission

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Open Journa. of Modelling a.d Simula.ion 2024年第2期12卷 59-73页

作者： Ja.ier Blecua.Jua. Fernández-Recio josé Ma.uel Gutiérrez Instituto de Ciencia. de la.Vid y del Vino (ICVV) CSIC-Universidad de La Rioja-Gobierno de La Rioja Logro&#241o Spain Depa.ta.ento de Ma.emá ticas y Computaci&#243n Universidad de La Rioja Logro&#241o Spain

The recent outbrea. of COVID-19 ha. ca.sed millions of dea.hs worldwide a.d a.huge societa. a.d economic impa.t in virtua.ly a.l countries. a.la.ge va.iety of ma.hema.ica. models to describe the dyna.ics of COVID-19 tra.smission ha.e been reported. a.ong them, Ba.esia. proba.ilistic models of COVID-19 tra.smission dyna.ics ha.e been very efficient in the interpreta.ion of ea.ly da.a.from the beginning of the pa.demic, helping to estima.e the impa.t of non-pha.ma.ologica. mea.ures in ea.h country, a.d foreca.ting the evolution of the pa.demic in different potentia. scena.ios. These models use proba.ility distribution curves to describe key dyna.ic a.pects of the tra.smission, like the proba.ility for every infected person of infecting other individua.s, dying or recovering, with pa.a.eters obta.ned from experimenta. epidemiologica. da.a. However, the impa.t of va.cine-induced immunity, which ha. been key for controlling the public hea.th emergency ca.sed by the pa.demic, ha. been more cha.lenging to describe in these models, due to the complexity of experimenta. da.a. Here we report different proba.ility distribution curves to model the a.quisition a.d deca. of immunity a.ter va.cina.ion. We discuss the ma.hema.ica. ba.kground a.d how these models ca. be integra.ed in existing Ba.esia. proba.ilistic models to provide a.good estima.ion of the dyna.ics of COVID-19 tra.smission during the entire pa.demic period.

关键词： COVID-19 Tra.smission Dyna.ics Proba.ilistic Model Ba.esia. a.a.ysis Ma.kov Cha.n Monte Ca.lo

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