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r.cent advances in the diagnosis of human schistosomiasis

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Asian Pacific Jour.al of Tr.pical Medicine 2008年第1期1卷 63-68页

作者： jones MK Austr.lian Centr. for.Inter.ational and Tr.pical Health Queensland Institute of Medical ResearchHerstonQueenslandAustraliaSchool of Veterinary ScienceThe University of QueenslandSt LuciaQueenslandAustralia

Schistosomiasis,caused by par.sitic bloodflukes of the genus Schistosoma,is a major.sour.e of human disease in developing tr.pical *** paper.r.views the diagnostic var.ous assays for.schistosomiasis,with par.icular.r.fer.nce to r.cent advances in assays incor.or.ting dir.ct par.sitological examination,ser.logy,antigen detection,and polymer.se chain r.action detection of par.site genetic mater.al.

关键词： schistosomiasis diagnosis par.sitology ser.logy

Chr.matic Mapping of Par.ial Dischar.e Signals

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高电压技术 2013年第10期39卷 2532-2540页

作者： M. r.gaa G. r. jones A. G. Deakin J. W. Spencer Nor.her. Power.r.d Castleford WF 10 5DS UK Depar.ment of Electr.cal Engineer.ng and Electr.nics Centre for Intelligent Monitoring Systems University of Liverpool Liverpool L69 3G J UK

This contr.bution descr.bes the use of chr.matic techniques for.quantifying signatur.s of par.ial dischar.es(PD).A br.ef descr.ption of the basis of chr.matic monitor.ng is given along with explanations of how the appr.ach may be applied for.addr.ssing signals pr.duced by *** test data fr.m sever.l sour.es for.differ.nt types of PDs,oper.ting conditions and geometr.es have been subjected to the chr.matic *** include a point-plane gap,a spher. in a liquid and tr.eing in a *** changes in PD signals have been investigated as a function of the amplitude of the alter.ating voltage pr.ducing the PD,the time dur.tion befor. full electr.cal br.akdown and for.differ.nt for.s of *** of the chr.matic pr.cessing of these data ar. pr.sented in the for. of a number.of chr.matic maps r.lating to differ.nt quar.er.cycles of the alter.ating voltage pr.ducing the *** r.sults show the potential of the chr.matic techniques for.indicating the likelihood of full electr.cal br.akdown and for.distinguishing between cer.ain for.s of PDs.A summar. of the chr.matic pr.cessing pr.cedur.s is pr.sented for.pr.ducing chr.matic maps and for.adaptation in fur.her.explor.ng PD signal featur.s.

关键词：局部放电信号 PD信号映射交流电压彩色地图测试数据几何形状操作条件

Leishmania tar.ntolae: an alter.ative appr.ach to the pr.duction of monoclonal antibodies to tr.at emer.ing vir.l infections

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Infectious Diseases of Pover.y 2015年第1期4卷 83-87页

作者： Joshua D jones Division of Vir.logy Department of PathologyUniversity of CambridgeTennis Court RoadCambridge CB21QPUK

Backgr.und:Monoclonal antibody ther.py has an impor.ant r.le to play as a post-exposur. pr.phylactic and ther.peutic for.the tr.atment of vir.l infections,including emer.ing *** example,sever.l patients of the pr.sent Ebola vir.s outbr.ak in West Afr.ca wer. tr.ated with ZMapp,a cocktail of thr.e monoclonal antibodies which ar. expr.ssed in Nicotiana ***:The major.ty of monoclonal antibodies in clinical use ar. expr.ssed in mammalian cell lines which offer.native folding and glycosylation of the expr.ssed *** antibody expr.ssion in vegetal systems offer. advantages over.expr.ssion in mammalian cell lines,including impr.ved potential for.scale up and r.duced *** this paper.I highlight the advantages of an upcoming pr.tozoal system for.the expr.ssion of r.combinant antibody *** tar.ntolae offer. a r.bust,economical expr.ssion of pr.teins with mammalian glycosylation patter.s expr.ssed in stable cell lines and gr.wn in suspension *** advantages of this system make it par.icular.y suited for.use in developing ***:Given the potential impor.ance of monoclonal antibody ther.py in the containment of emer.ing vir.l infections,novel and alter.ative str.tegies to impr.ve pr.duction must be explor.d.

关键词： Antibody Ebola Emer.ing Expr.ssion Infection Leishmania Monoclonal Ther.py

Per.pectives for.the r.cover. of r.r. ear.hs fr.m end-of-life fluor.scent lamps

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Jour.al of r.r. Ear.hs 2014年第3期32卷 195-200页

作者： K.Binnemans P.T.jones Depar.ment of Chemistr. KU Leuven – University of LeuvenCelestijnenlaan 200F- box 2404 B-3001 Heverlee Belgium Depar.ment of Metallur.y and Mater.als Engineer.ng KU Leuven – University of LeuvenKasteelpark Arenberg 44 - box 2450 B-3001 Heverlee Belgium

This vision paper.discusses the advantages and disadvantages of the thr.e main options for.the r.cycling of r.r.-ear.h ele- ments fr.m end-of-life fluor.scent lamps：（1） dir.ct r.-use of the lamp phosphor.mixtur.; （2） separ.tion of the lamp phosphor.mixtur. into the differ.nt phosphor.components; （3） r.cover. of the r.r.-ear.h content. An over.iew is given of commer.ial activities in Eur.pe in the domain of r.cycling of mater.als fr.m end-of-life fluor.scent lamps and the r.cover. of r.r. ear.hs fr.m these lamps. The collection of end-of-life fluor.scent lamps is cur.ently dr.ven by a legal fr.mewor. that pr.hibited the r.lease of mer.ur. to the envir.nment. The contaminations of the lamp phosphor.powder. by mer.ur. and by small glass par.icles of cr.shed fluor.scent lamps ar. limiting factor. in the r.cycling pr.cess. r.sear.h should be dir.cted to an advanced clean-up of the r.claimed lamp phosphor.fr.ction, and in par.icular.to the r.moval of mer.ur. and glass fr.gments. The r.cover. of r.r. ear.hs fr.m the lamp phosphor. could be facilitated by taking advantage of the differ.nces in r.sistance of the differ.nt lamp phosphor. by chemical attack by inor.anic ac- ids and bases.

关键词： balance pr.blem fluor.scence lamps lamp phosphor. lanthanides r.r.-ear.h elements r.cycling ur.an mining

Contempor.r. management 3r. ed. 3rd ed.

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Affect and pr.fr.ntal hemodynamics dur.ng exer.ise under.immer.ive audiovisual stimulation:Impr.ving the exper.ence of exer.ise for.over.eight adults

2003年

作者： Gar.th r. jones Jennifer.M. Geor.e

Includes index.

ISBN: (纸本)0071151214

Includes index.

关键词： Management.

来源：畅想之星图书光盘版（南... 畅想之星图书光盘版（南... 评论

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Jour.al of Spor. and Health Science 2019年第4期8卷 325-338页

作者： Leighton jones Panteleimon Ekkekakis Academy of Spor. and Physical Activity Sheffield Hallam UniversitySheffieldS10 2BPUK Depar.ment of Kinesiology Iowa State UniversityAmesIA 50011USA

Objective:r.sear.h on methods of impr.ving the affective exper.ence of exer.ise r.mains limited,especially for.low-active over.eight *** investigated the effectiveness of a vir.ual-r.ality headset and headphones in impr.ving affective r.sponses over.conventionally deliver.d audiovisual ***:Low-active,over.eight adults(16 women,5 men;age:34.67±9.62 year.;body mass index:28.56±4.95 kg/m^2;peak oxygen uptake for.men:29.14±6.56 mL/kg/min,for.women:22.67±4.52 mL/kg/min,mean±SD)completed 15-min sessions of r.cumbent cycling at the ventilator. thr.shold:(a)high immer.ion(HI,vir.ual r.ality headset and headphones),(b)low immer.ion(LI,television scr.en and speaker.),and(c)***-exer.ise pleasur. and post-exer.ise enj oyment wer. *** of the r.ght dor.olater.l pr. fr.ntal cor.ex(dIPFC)was assessed with near.infr.r.d ***:Higher.pleasur. was r.por.ed dur.ng HI than dur.ng LI and Contr.l(Condition×Time inter.ction;pr.icipants who r.por.ed a pr.fer.nce for.low exer.ise intensity showed higher.dIPFC oxygenation dur.ng Contr.l,but this differ.nce diminished dur.ng LI and HI(Condition×Time×Pr.fer.nce inter.ction;p=0.036,ηp^2=0.10).Conclusion:Compar.d with conventionally deliver.d audiovisual stimulation,using a vir.ual-r.ality headset str.ngthens the dissociative effect,fur.her.impr.ving affective r.sponses to exer.ise at the ventilator. thr.shold among over.eight,low-active *** by competing with inter.ceptive affer.nts at the level of sensor. input,audiovisual stimulation may lessen r.liance on cognitive effor.s to attenuate declining affect,as indicated by lower.r.ght dIPFC activity,par.icular.y among par.icipants disinclined towar. high exer.ise intensity.

关键词： Affective valence Enjoyment Immer.ion Music Video

Pancr.atic cancer. A r.view of clinical diagnosis, epidemiology, tr.atment and outcomes

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Wor.d Jour.al of Gastr.enter.logy 2018年第43期24卷 4846-4861页

作者： Andr.w McGuigan Paul Kelly r.char. C Tur.ington Clair. jones Helen G Coleman r.Stephen McCain Centr. for.Cancer.r.sear.h and Cell Biology Queen’s University Belfast Depar.ment of Pathology Royal Victoria HospitalBelfast Depar.ment of Hepatobiliar. Sur.er. Mater Hospital Centr. for.Public Health Queen’s University Belfast

This r.view aims to outline the most up-to-date knowledge of pancr.atic adenocar.inoma r.sk, diagnostics, tr.atment and outcomes, while identifying gaps that aim to stimulate fur.her.r.sear.h in this under.tudied malignancy. Pancr.atic adenocar.inoma is a lethal condition with a r.sing incidence, pr.dicted to become the second leading cause of cancer.death in some r.gions. It often pr.sents at an advanced stage, which contr.butes to poor.five-year.sur.ival r.tes of 2%-9%, r.nking fir.ly last amongst all cancer.sites in ter.s of pr.gnostic outcomes for.patients. Better.under.tanding of the r.sk factor. and symptoms associated with this disease is essential to infor. both health pr.fessionals and the gener.l population of potential pr.ventive and/or.ear.y detection measur.s. The identification of high-r.sk patients who could benefit fr.m scr.ening to detect pr.-malignant conditions such as pancr.atic intr.epithelial neoplasia, intr.ductal papillar. mucinous neoplasms and mucinous cystic neoplasms is ur.ently r.quir.d, however.an acceptable scr.ening test has yet to be identified. The management of pancr.atic adenocar.inoma is evolving, with the intr.duction of new sur.ical techniques and medical ther.pies such as lapar.scopic techniques and neo-adjuvant chemor.diother.py, however.this has only led to modest impr.vements in outcomes. The identification of novel biomar.er. is desir.ble to move towar.s a pr.cision medicine er., wher. pancr.atic cancer.ther.py can be tailor.d to the individual patient, while unnecessar. tr.atments that have negative consequences on quality of life could be pr.vented for.other.. r.sear.h effor.s must also focus on the development of new agents and deliver. systems. Over.ll, consider.ble pr.gr.ss is r.quir.d to r.duce the bur.en associated with pancr.atic cancer. r.cent, r.newed effor.s to fund lar.e consor.ia and r.sear.h into pancr.atic adenocar.inoma ar. welcomed, but fur.her.str.ams will be necessar. to facilitate the momentum needed to

关键词： Pancr.atic cancer Pancr.atic adenocar.inoma Pancr.atic cancer.r.sk factor. Pancr.atic cancer.tr.atment

Outcomes of Pr.ngle maneuver.in patients under.oing hepatic r.section for.color.ctal liver.metastases

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Hepatobiliar. & Pancr.atic Diseases Inter.ational 2021年第6期20卷 588-591页

作者： Li Lian Kuan Chr.stopher.P Neal Vaux r.ber.son Michael jones Ashley r.Dennison Giuseppe Gar.ea Depar.ment of Hepatobiliar. and Pancr.atic Sur.er. Leicester General HospitalUniversity Hospitals of Leicester NHS TrustLeicester LE54PWUK Discipline of Sur.er. The Queen Elizabeth HospitalThe University of AdelaideAdelaideSouth AustraliaAustralia

To the Editor.The Pr.ngle maneuver.PM)was initially descr.bed mor. than a centur. ago to contr.l bleeding associated with hepatic tr.uma and it r.mains the most common method to block hepatic inflow and minimize blood... 详细信息

关键词： hepatic Pr.ngle r.section

Sever. acute pancr.atitis： pathogenesis, diagnosis and sur.ical management

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Hepatobiliar. & Pancr.atic Diseases Inter.ational 2017年第2期16卷 155-159页

作者： Mar. Por.elli Chr.stopher.David jones Depar.ment of Gener.l Sur.er. University Hospital Ayr Ayr KA6 6DX UK

BACKGr.UND： Sever. acute pancr.atitis is a subtype of acute pancr.atitis, associated with multiple or.an failur. and systemic inflammator. r.sponse syndr.me. In this qualitative r.view we looked at the pr.nciples of pathogenesis, classification and sur.ical management of sever. acute pancr.atitis. We also looked at the cur.ent shift in par.digm in the management of sever. acute pancr.atitis since the guideline developed by the Br.tish Society of *** SOUr.ES： Studies published between 1st Januar. 1991 and 31st December.2015 wer. identified with Pub Med, MEDLINE, EMBASE and Google Scholar.online sear.h engines using the following Medical Subject Headings： “acute pancr.atitis, necr.sis, mor.ality, pathogenesis, incidence” and the ter.s “open necr.sectomy and minimally invasive necr.sectomy”.The National Institute of Clinical Excellence（NICE） Guidelines wer. also included in our.study. Inclusion cr.ter.a for.our.clinical r.view included established guidelines, r.ndomized contr.lled tr.als and non-r.ndomized contr.lled tr.als with a follow-up dur.tion of mor. than 6 ***： The incidence of sever. acute pancr.atitis within the UK is significantly r.sing and pathogenetic theor.es ar. still contr.ver.ial. In developed countr.es, the most common cause is biliar. calculi. The Br.tish Society of Gastr.enter.logy,acknowledges the r.vised Atlanta cr.ter.a for.pr.diction of sever.ty. A newer.Deter.inant-based system has been *** pr.nciple of sur.ical management of acute necr.tizing pancr.atitis r.quir.s intensive car. management, identifying infection and if indicated, debr.dement of any infected necr.tic ar.a. The cur.ent pr.cedur.s opted for.include standar. sur.ical open necr.sectomy, endoscopic necr.sectomy and minimally invasive necr.sectomy. The cur.ent par.digm is shifting towar.s a step-up ***： Sever. acute pancr.atitis is still a subject of gr.y ar.as in its sur.ical management even though new studies have been r.cor.e

关键词： sever. acute pancr.atitis acute pancr.atitis necr.sis mor.ality pathogenesis incidence open necr.sectomy and minimally invasive necr.sectomy