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Postprandial triglyceride metabolism in elderly men with subnormal testosterone levels

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Asian Journal of Andrology 2008年第4期10卷 542-549页

作者： Ingvild Agledahl john-Bjarne hansen Johan Svartberg Department of Medicine University Hospital of North Norway TromsO 9038 Norway Center for Atherothrombotic Research in TromsФ （CART） Institute of Clinical Medicine University of TromsФ TromsФ 9037 Norway institute of Clinical Medicine University of TromsФ TromsФ 9037 Norway

Aim： To investigate the level of postprandial triglycerides （TG）s in elderly men with subnormal testosterone level （≤ 11.0 nmol/L） compared to men with normal testosterone level （〉 11.0 nmol/L）. Methods： Thirthy-seven men with subnormal and 41 men with normal testosterone aged 60-80 years underwent an oral fat load and TG levels were measured fasting and 2, 4, 6 and 8 h afterwards. Results： Men with subnormal testosterone had significantly higher body mass index （BMI） and waist circumference （P 〈 0.001） than men with normal testosterone. They had significantly higher area under curve （AUC, P = 0.037）, incremental area under curve （AUCi, P = 0.035） and TG response （TGR, P = 0.014） for serum-TG and significantly higher AUC （P = 0.023）, AUCi （P = 0.023） and TGR （P = 0.014） for chylomicron-TG compared to men with normal testosterone level. Adjusting for waist circumference erased the significant differences between the groups in postprandial triglyceridemia. Conclusion： Men with subnormal testosterone have increased postprandial TG levels indicating an impaired metabolism of postprandial TG-rich lipoproteins （TRL）, which may add to an unfavourable lipid profile and promote development of atherosclerosis.

关键词： testosterone sex hormone-binding globulin postprandial triglycerides abdominal obesity waist circumference

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奈特解剖涂色书

作者： (美)john T. hansen

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一种经济高效的电子战系统仿真方法

中国电子商情 2015年第6期 36-38页

作者： john S hansen 是德科技公司

电子战（EW）的概念非常宽泛,但通常都包括干扰敌方使用电磁波谱（EMS）,或通过分析敌方有意或无意发送的电磁（EM）信号,以收集有关敌方行动计划或作战能力的情报。仿真电子战系统在现场遇到的频谱环境是一项极其复杂的任务,这需要超... 详细信息

电子战（EW）的概念非常宽泛,但通常都包括干扰敌方使用电磁波谱（EMS）,或通过分析敌方有意或无意发送的电磁（EM）信号,以收集有关敌方行动计划或作战能力的情报。仿真电子战系统在现场遇到的频谱环境是一项极其复杂的任务,这需要超乎想象的高效率且经过验证的测试操作能力。同时,严格的预算使电子战测试面临新的挑战。

关键词：电子战系统频谱环境系统仿真测试操作电磁波谱作战能力仿真要求系统集成在现场波形存储器

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基于情境感知的服务系统(英文)

计算机系统应用 2009年第6期18卷 161-167页

作者： Jφrgen Staunstrup 童缙郁莲李伟平林慧苹褚伟杰 john Paulin hansen Arne Glenstrup Thomas Hildebrandt 哥本哈根信息技术大学北京大学软件与微电子学院北京102600

The paper gives an overview of a recently started research project addressing the question:Can context be exploited to add value to IT-services?Beyond today's way-finding services based on GPS and maps,we believe there is a new class of context-aware pervasive services making good use of a broad range of context information(***,time of day,temperature,history as well as relative location of friends and belongings).Last but not least we believe one can find ways of adding value to IT-services by using disembodied conversational agents based on voice,sounds and visual signals integrated into the environment, instead of being guided by explicit directions shown on a *** project aims at giving both new fundamental insight about the theory behind IT-services,their architecture and user interfaces and at building a number of prototypes demonstrating innovative context-aware pervasive IT-services.

关键词：情境感知服务系统 GPS 全球定位系统

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支持两种总线宽度的单板机

电子设计技术 1996年第4期 56-56页

作者： john hansen Advanced Micro Devices Austin TX

图1中的设计允许单板机支持8位和16位总线宽度。8位Am186EMμC采用两块SRAM,并含有0Ω电阻器或跨接线,连接A;和WHB到SRAM。16位Am188EMμC采

关键词：单板机纳秒

Fructose-sorbitol ingestion provokes gastrointestinal symptoms in patients with eating disorders

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World Journal of Gastroenterology 2009年第42期15卷 5295-5299页

作者： Noel Friesen Ross D hansen Suzanne F Abraham john E Kellow Department of Obstetrics and Gynaecology Royal North Shore HospitalUniversity of SydneySydney 2065Australia Department of Gastroenterology Royal North Shore HospitalUniversity of SydneySydney 2065Australia

AIM:To evaluate gastrointestinal(GI) symptoms and breath hydrogen responses to oral fructose-sorbitol(F-S) and glucose challenges in eating disorder(ED) ***:GI symptoms and hydrogen breath concentration were monitored in 26 female ED inpatients for 3 h,following ingestion of 50 g glucose on one day,and 25 g fructose/5 g sorbitol on the next day,after an overnight fast on each *** to F-S were compared to those of 20 asymptomatic healthy ***:F-S provoked GI symptoms in 15 ED patients and one healthy control(P 17.5 kg/m 2(P < 0.01) .There were no differences in psychological scores,prevalence of functional GI disorders or breath hydrogen responses between patients with and without an F-S ***:F-S,but not glucose,provokes GI symptoms in ED patients,predominantly those with low *** findings are important in the dietary management of ED patients.

关键词： Fructose Sorbitol Malabsorption syndromes Functional gastrointestinal disorders Eating disorders Underweight

Simultaneous endoscopic and video-assisted retroperitoneal debridement in walled-off pancreatic necrosis using a laparoscopic access platform:Two case reports

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World Journal of Gastroenterology 2022年第5期28卷 588-593页

作者： Lars Lindgaard Morten Laksáfoss Lauritsen Srdan Novovic Erik Feldager hansen john Gásdal Karstensen Palle Nordblad Schmidt Pancreatitis Centre East(PACE) Gastro UnitCopenhagen University Hospital-Amager and HvidovreHvidovre 2650Capital RegionDenmark Department of Clinical Medicine University of CopenhagenCopenhagen 2100Capital RegionDenmark

BACKGROUND Infected walled-off necrosis is a potentially life-threatening complication of necrotizing *** some patients can be treated by drainage alone,many patients also need evacuation of the infected *** necroses in relation to the pancreatic bed are easily reached via an endoscopic transluminal approach,whereas necroses that involve the paracolic gutters and the pelvis are most efficiently treated via a percutaneous *** and complex necroses may need a combination of the two *** SUMMARY Transluminal and percutaneous drainage followed by simultaneous endoscopic and modified video-assisted retroperitoneal debridement was carried out in two patients with very large(32-38 cm),infected walled-off necroses using a laparoscopic access *** 34 d and 86 d and a total of 9 and 14 procedures,respectively,complete regression of the walled-off necroses was *** laparoscopic access platform improved both access to the cavities as well as the *** transluminal and percutaneous necrosectomy are feasible with the laparoscopic access platform serving as a useful *** This approach may be necessary to control infection and achieve regression in some patients with complex collections.

关键词： Acute necrotizing pancreatitis Walled-off necroses Minimally invasive surgical procedures

Ineffective oesophageal motility:Manometric subsets exhibit different symptom profiles

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World Journal of Gastroenterology 2008年第23期14卷 3719-3724页

作者： Horst Gunter Haack Ross David hansen Allison Malcolm john Edward Kellow Department of Gastroenterology Gastrointestinal Investigation UnitRoyal North Shore HospitalUniversity of SydneyAustralia

AIM:To compare the demographic and clinical features of different manometric subsets of ineffective oesophageal motility(IOM;defined as ≥ 30% wet swallows with distal contractile amplitude < 30 mmHg) ,and to determine whether the prevalence of gastro-oesophageal reflux differs between IOM subsets. METHODS:Clinical characteristics of manometric subsets were determined in 100 IOM patients(73 female,median age 58 years) and compared to those of 100 age-and gender-matched patient controls with oesophageal symptoms,but normal manometry. Supine oesophageal manometry was performed with an eight-channel DentSleeve water-perfused catheter,and an ambulatory pH study assessed gastro-oesophageal reflux. RESULTS:Patients in the IOM subset featuring a majority of low-amplitude simultaneous contractions(LASC) experienced less heartburn(prevalence 26%) ,but more dysphagia(57%) than those in the IOM subset featuring low-amplitude propagated contractions(LAP;heartburn 70%,dysphagia 24%;both P ≤ 0.01) . LASC patients also experienced less heartburn and more dysphagia than patient controls(heartburn 68%,dysphagia 11%;both P < 0.001) . The prevalence of heartburn and dysphagia in IOM patients featuring a majority of non-transmitted sequences(NT) was 54%(P = 0.04 vs LASC) and 36%(P < 0.01 vs controls) ,respectively. No differences inage and gender distribution,chest pain prevalence,acid exposure time(AET) and symptom/reflux association existed between IOM subsets,or between subsets and controls. CONCLUSION:IOM patients with LASC exhibit a different symptom profile to those with LAP,but do not differ in gastro-oesophageal reflux prevalence. These findings raise the possibility of different pathophysiological mechanisms in IOM subsets,which warrants further investigation.

关键词： Age Dysphagia Heartburn Ineffective oesophageal motility Oesophageal manometry Simultaneous contractions

Dietary stimulation of the endogenous somatotropic axis in weaner and growerfinisher pigs using medium chain triglycerides and cysteamine hydrochloride

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Journal of Animal Science and Biotechnology 2017年第2期8卷 405-416页

作者： David W.Miller Zoe Prosser Edward Y.W.Chee Christian F.hansen Frank R.Dunshea Bruce P.Mullan john R.Pluske School of Veterinary and Life Sciences Murdoch UniversityMurdochWA6150Australia Department of Large Animal Sciences Faculty of Health and Medical SciencesUniversity of CopenhagenGroennegaardsvej 21870 Frederiksberg CDenmark Melbourne School of Land and Environment University of MelbourneParkvilleVlC 3051Australia Department of Agriculture and Food Western Australia Bentley Delivery CenterLocked Bag4BentleyWA 6983Australia

Background： Three experiments were conducted to examine the overall hypothesis that addition of medium chain triglycerides（MCT） and cysteamine hydrochloride（CSH） into the diets of young and growing pigs would stimulate the endogenous somatotropic axis to improve growth and ***： In Experiment 1, weaner pigs were given either a 5 d dietary supplement of 5 % MCT（n = 8） or a control diet（n = 8）. MCT increased the plasma concentration of growth hormone（GH; P ＆lt; 0.05） and the GH secretagogue,ghrelin（P ＆lt; 0.05）. Additionally, the MCT treatment reduced scouring（P ＆lt; 0.05）, maintained villous height in the small intestine（P ＆lt; 0.05） and stabilised daily weight gain（P ＆lt; 0.05）, compared to the controls. Experiment 2compared the effects of 4 levels（0, 1, 3 and 6 % v/v） of MCT supplementation in grower-finisher male pigs, of approximately 35 kg live weight（n = 15 per treatment）. Blood samples taken after 7 wk of treatment showed that the MCT supplementation increased circulating ghrelin（P ＆lt; 0.001）, GH（P ＆lt; 0.01） and insulin（P ＆lt; 0.05）concentrations in a dose-dependent manner. Daily weight gain, feed intake and feed conversion ratio were not affected by the MCT diets. In Experiment 3, 64 female pigs of approximately 60 kg live weight were allocated to one of three dietary treatments： control（n = 20）; 6 % MCT（n = 21）; and 70 mg/kg CSH（n = 21）. After 3 wk of supplementation, the MCT treated pigs had a higher plasma concentration of ghrelin compared to the control and CSH pigs（P ＆lt; 0.05）. Plasma concentrations of GH and weight were not affected by any of the dietary ***： Evidence is provided in Experiment 1 to support the use of dietary MCT supplements, perhaps acting via stimulation of somatotropic endocrine pathways, to minimise weaning-associated disorders such as slowing of growth and diarrhoea. In Experiments 2 and 3, although there was no effect on weight gain or feed conversion ratio in either experiment, MCT and CSH incr

关键词： Ghrelin Growth Pig Somatotropin

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