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A Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults—China,2017–2021

China CDC weekly 2024年第23期6卷 537-541,I0001-I0007页

作者： Yidan Qiu Saisai Ji chen chen Jinhui Zhou Jun Wang Bing Wu Yuan Wei Fangyu Li Xulin Zheng Lanjing Xu Zheng Zhang Feng Zhao Guangdi chen john SJi Yuebin Lyu Shilu Tong Xiaoming Shi Department of Big Data in Health Science School of Public HealthZhejiang UniversityHangzhou CityZhejiang ProvinceChina China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina Center for Global Health School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of Epidemiology and Biostatistics School of Public HealthJilin UniversityChangchun CityJilin ProvinceChina School of Public Health China Medical UniversityShenyang CityLiaoning ProvinceChina Institute of Environmental Health School of Public Healthand Bioelectromagnetics LaboratorySchool of MedicineZhejiang UniversityHangzhou CityZhejiang ProvinceChina Environmental Research Center Duke Kunshan UniversityKunshan CityJiangsu ProvinceChina Nicholas School of the Environment Duke UniversityDurhamNCUSA School of Public Health Institute of Environment and Population HealthAnhui Medical UniversityHefei CityAnhui ProvinceChina School of Public Health and Social Work Queensland University of TechnologyBrisbaneAustralia

What is already known about this topic?Antimony(Sb)has been identified as a new neurotoxicant that impacts neurological functions in animal ***,its effects on the human population remain *** is added by this report?The study reveals that there is an association between exposure to Sb and a higher incidence of cognitive impairment in older *** dose-response curve demonstrates that the risk of cognitive impairment consistently increased with higher levels of Sb exposure without a discernible *** are the implications for public health practice?Reducing exposure to Sb may have a beneficial effect in delaying or preventing the onset of cognitive *** intervention has the potential to significantly decrease the disease burden associated with cognitive impairment,ultimately contributing to social development.

关键词： Antimony development. exposure

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等通道角挤压制备细晶ZK60镁合金的组织与力学性能

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中国有色金属学报 2010年第12期20卷 2274-2282页

作者：何运斌潘清林覃银江刘晓艳李文斌 Yu-lung CHIU john J J chen 中南大学材料科学与工程学院长沙410083 Department of Chemical and Materials Engineering University of Auckland

利用两种等通道角挤压(ECAP)方法(普通单步ECAP和两步ECAP)制备细晶ZK60合金。采用金相显微镜、扫描电镜、透射电镜和X射线衍射仪对合金的组织和织构进行观察,通过拉伸试验研究不同ECAP方法对合金力学性能的影响。结果表明:与单步ECAP... 详细信息

利用两种等通道角挤压(ECAP)方法(普通单步ECAP和两步ECAP)制备细晶ZK60合金。采用金相显微镜、扫描电镜、透射电镜和X射线衍射仪对合金的组织和织构进行观察,通过拉伸试验研究不同ECAP方法对合金力学性能的影响。结果表明:与单步ECAP变形相比,两步ECAP变形,由于降低了变形温度,晶粒细化效果更好;经过(240℃,4道次)+(180℃,4道次)两步ECAP变形后,合金晶粒细化至约0.8μm;合金的力学性能与材料的织构密切相关,由于存在织构软化效应,与挤压态相比,经单步ECAP变形后合金的强度有所降低,而伸长率明显提高;但经两步ECAP变形后,由于细晶强化和亚结构强化的作用,合金的强度得到提高。

关键词： ZK60镁合金等通道角挤压显微组织力学性能动态回复再结晶织构

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Three-dimensional thermochemical model and melt distribution beneath Northeast China

Three-dimensional thermochemical model and melt distribution...

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2020年中国地球科学联合学术年会

作者： Anqi Zhang Zhen Guo Juan Carlos Afonso Y.john chen Southern University of Science and Technology Macquarie University

Intraplate volcanisms spanning from the Late Cretaceous to present are widespread in Northeast China(NEC). Numerous geophysical and geochemical studies have been carried out during the past few decades to explore the origin and mantle dynamic of these intraplate volcanisms. However, the hypotheses put forward for the geodynamic evolution of the region are diverse and often controversial, such as mantle plume, mantle upwelling originates from the transition zone, small-scale convection, and the influx of fluid released from the stagnant slab of the Pacific plate in the mantle transition zone.

关键词： Three-dimensional thermochemical model and melt distribution beneath Northeast China

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Seismic azimuthal anisotropy of NE Tibet from seismic ambient noise DBF tomography: implication for crustal deformation

Seismic azimuthal anisotropy of NE Tibet from seismic ambien...

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2022年中国地球科学联合学术年会

作者： Xiaoyang Wu Zhen Guo Shilin Li Yong Yu Yongshun john chen

We present a double beamforming tomography (DBF) method to extract both phase velocity and azimuthal anisotropy directly from seismic ambient noise cross-correlations. With the dense seismic network ChinArray-Himalaya II, we imaged Rayleigh wave phase velocities and azimuthal anisotropy in the northeastern Tibetan Plateau for periods of 8–40 s. We then inverted 3-D anisotropic shear wave velocity model of the crust beneath northeastern Tibet (NE Tibet).

关键词： DBF Seismic azimuthal anisotropy of NE Tibet from seismic ambient noise DBF tomography implication for crustal deformation

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The role of optical coherence tomography in neuro-ophthalmology

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Annals of Eye Science 2018年第1期3卷 228-245页

作者： john J.chen Fiona Costello Department of Ophthalmology Mayo ClinicRochesterMinnesotaUSA Department of Neurology Mayo ClinicRochesterMinnesotaUSA Departments of Surgery University of CalgaryCalgaryAlbertaCanada Clinical Neurosciences University of CalgaryCalgaryAlbertaCanada

Optical coherence tomography(OCT)is an ocular imaging technique that can complement the neuro-ophthalmic assessment,and inform our understanding regarding functional consequences of neuroaxonal injury in the afferent visual ***,OCT has emerged as a surrogate end-point in the diagnosis and follow up of several demyelinating syndromes of the central nervous system(CNS),including optic neuritis(ON)associated with:multiple sclerosis(MS),neuromyelitis optica spectrum disorder(NMOSD),and anti-myelin oligodendrocyte glycoprotein(MOG)*** advancements in enhanced depth imaging(EDI)OCT have distinguished this technique as a new gold standard in the diagnosis of optic disc drusen(ODD).Moreover,OCT may enhance our ability to distinguish cases of papilledema from pseudopapilledema caused by *** the setting of idiopathic intracranial hypertension(IIH),OCT has shown benefit in tracking responses to treatment,with respect to reduced retinal nerve fiber layer(RNFL)measures and morphological changes in the angling of Bruch’s *** follow up of OCT measured ganglion cell-inner plexiform layer thickness may be of particular value in managing IIH patients who have secondary optic *** of compressive optic neuropathies may be readily diagnosed with OCT,even in the absence of overt visual field ***,OCT values may offer some prognostic value in predicting post-operative outcomes in these ***,OCT can be indispensable in differentiating optic neuropathies from retinal diseases in patients presenting with vision loss,and an unrevealing fundus *** this review,our over-arching goal is to highlight the potential role of OCT,as an ancillary investigation,in the diagnosis and management of various optic nerve disorders.

关键词： Optical coherence tomography(OCT) retinal nerve fiber layer(RNFL) ganglion cell-inner plexiform layer(GCIP)thickness optic neuritis(ON) optic disc drusen(ODD)

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高温透明铝电解槽中50 cm^(2)石墨阳极上气泡析出行为

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中国有色金属学报 2021年第7期31卷 1933-1943页

作者：关月超王壮牛宏坤杨酉坚王兆文高炳亮 LIU Jingjing Mark P TAYLOR john J J chen 东北大学冶金学院沈阳110819 Department of Chemical and Materials Engineering University of AucklandAuckland 1142New Zealand

铝电解阳极气泡行为对研究电解质流场模拟和阳极效应都至关重要。本文采用高温透明电解槽观测了底面积为50 cm^(2)(10 cm×5 cm)的石墨阳极上的气泡行为,实验温度为924℃。结果表明:在阳极电流密度为0.3~1.7A/cm^(2)范围内,最大气体覆... 详细信息

铝电解阳极气泡行为对研究电解质流场模拟和阳极效应都至关重要。本文采用高温透明电解槽观测了底面积为50 cm^(2)(10 cm×5 cm)的石墨阳极上的气泡行为,实验温度为924℃。结果表明:在阳极电流密度为0.3~1.7A/cm^(2)范围内,最大气体覆盖率在48%~65%之间,与工业电解槽炭阳极上的最大气体覆盖率相近,低于文献中小尺寸阳极上观测到的60%~100%。通过SEM/EDS分析发现,气泡成核的优先位置与炭阳极表面的层状结构位置吻合,层状碳结构对CO_(2)气泡润湿性好于致密碳结构,并抑制二氧化碳气泡的滑动,促进大气泡的生成。

关键词：铝电解透明电解槽炭阳极对电解质的润湿性气泡行为气泡成核

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Biomimetic natural biomaterials for tissue engineering and regenerative medicine:new biosynthesis methods,recent advances,and emerging applications

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Military Medical Research 2024年第1期11卷 50-79页

作者： Shuai Liu Jiang-Ming Yu Yan-Chang Gan Xiao-Zhong Qiu Zhe-chen Gao Huan Wang Shi-Xuan chen Yuan Xiong Guo-Hui Liu Si-En Lin Alec McCarthy johnson V.john Dai-Xu Wei Hong-Hao Hou Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering the Fifth Affiliated HospitalSchool of Basic Medical ScienceSouthern Medical UniversityGuangzhou 510900China Department of Orthopedics Tongren HospitalShanghai Jiao Tong UniversityShanghai 200336China The Eighth Affiliated Hospital Sun Yat-Sen UniversityShenzhen 518033GuangdongChina Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325011ZhejiangChina Department of Orthopedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Orthopaedics and Traumatology Faculty of Medicinethe Chinese University of Hong KongHong Kong SAR 999077China Department of Functional Materials Terasaki Institute for Biomedical InnovationLos AngelesCA 90064USA Mary&Dick Holland Regenerative Medicine Program College of MedicineUniversity of Nebraska Medical CenterOmahaNE 68130USA Zigong Affiliated Hospital of Southwest Medical University Zigong Psychiatric Research CenterZigong Institute of Brain ScienceZigong 643002SichuanChina Key Laboratory of Resource Biology and Biotechnology in Western China Ministry of EducationSchool of MedicineDepartment of Life Sciences and MedicineNorthwest UniversityXi’an 710127China

Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering(TE)and regenerative *** contrast to conventional biomaterials or synthetic materials,biomimetic scaffolds based on natural biomaterial can offer cells a broad spectrum of biochemical and biophysical cues that mimic the in vivo extracellular matrix(ECM).Additionally,such materials have mechanical adaptability,micro-structure interconnectivity,and inherent bioactivity,making them ideal for the design of living implants for specific applications in TE and regenerative *** paper provides an overview for recent progress of biomimetic natural biomaterials(BNBMs),including advances in their preparation,functionality,potential applications and future *** highlight recent advances in the fabrication of BNBMs and outline general strategies for functionalizing and tailoring the BNBMs with various biological and physicochemical characteristics of native ***,we offer an overview of recent key advances in the functionalization and applications of versatile BNBMs for TE ***,we conclude by offering our perspective on open challenges and future developments in this rapidly-evolving field.

关键词： Biomimic Scaffold Biosynthesis Natural biomaterial Tissue engineering

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道家思想对加拿大华裔英语文学的深远影响

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内蒙古大学学报（哲学社会科学版） 2010年第1期42卷 117-121页

作者：陈中明加拿大温哥华环球中华文化学院/英属哥伦比亚大学

自20世纪70年代以来,加拿大文坛相继出现了一批华裔英语作家。在他们创作的诗歌、小说和戏剧等文学作品中体现出了道家思想或道家哲理。目前,关于这些作品的研究绝大多数仍流于表面或单向的探索,尚未从整个价值体系和哲理性高度来梳理... 详细信息

自20世纪70年代以来,加拿大文坛相继出现了一批华裔英语作家。在他们创作的诗歌、小说和戏剧等文学作品中体现出了道家思想或道家哲理。目前,关于这些作品的研究绝大多数仍流于表面或单向的探索,尚未从整个价值体系和哲理性高度来梳理华裔文学所体现的文化现象,也尚未归纳到一定的理论高度和全球性意义。以颇具代表性的文本为研究基点,可以看出,在加拿大华裔英语文学作品中体现出了回归和弘扬并光大华夏道家的思想;加拿大华裔作家对中国文学和文化寻根溯源,努力发掘和弘扬中国传统文化对世界的影响和价值。

关键词：道家思想道家哲学和美学加拿大华裔英语文学中国文化

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Low-Cost Federated Broad Learning for Privacy-Preserved Knowledge Sharing in the RIS-Aided Internet of Vehicles

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Engineering 2024年第2期33卷 178-189页

作者： Xiaoming Yuan Jiahui chen Ning Zhang Qiang(john)Ye Changle Li Chunsheng Zhu Xuemin Sherman Shen Qinhuangdao Branch Campus Northeastern UniversityQinhuangdao 066004China State Key Laboratory of Integrated Services Networks&the Research Institute of Smart Transportation Xidian UniversityXi’an 710071China Department of Electrical and Computer Engineering University of WindsorWindsorON N9B 3P4Canada Department of Electrical and Software Engineering University of CalgaryCalgaryAB T2N 1N4Canada SUSTech Institute of Future Networks Southern University of Science and TechnologyShenzhen 518055China Department of Electrical and Computer Engineering University of WaterlooWaterlooON N2L 3G1Canada

High-efficiency and low-cost knowledge sharing can improve the decision-making ability of autonomous vehicles by mining knowledge from the Internet of Vehicles(IoVs).However,it is challenging to ensure high efficiency of local data learning models while preventing privacy leakage in a high mobility *** order to protect data privacy and improve data learning efficiency in knowledge sharing,we propose an asynchronous federated broad learning(FBL)framework that integrates broad learning(BL)into federated learning(FL).In FBL,we design a broad fully connected model(BFCM)as a local model for training client *** enhance the wireless channel quality for knowledge sharing and reduce the communication and computation cost of participating clients,we construct a joint resource allocation and reconfigurable intelligent surface(RIS)configuration optimization framework for *** problem is decoupled into two convex *** to improve the resource scheduling efficiency in FBL,a double Davidon–Fletcher–Powell(DDFP)algorithm is presented to solve the time slot allocation and RIS configuration *** on the results of resource scheduling,we design a reward-allocation algorithm based on federated incentive learning(FIL)in FBL to compensate clients for their *** simulation results show that the proposed FBL framework achieves better performance than the comparison models in terms of efficiency,accuracy,and cost for knowledge sharing in the IoV.

关键词： Knowledge sharing Internet of Vehicles Federated learning Broad learning Reconfigurable intelligent surfaces Resource allocation

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注重学习过程考核的加拿大微积分课程教学——布兰登大学的微积分课程教学给我们的启示

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大连大学学报 2019年第6期40卷 129-132页

作者：王红丽 john chen 大连大学信息工程学院辽宁大连116622 布兰登大学数学和计算机科学系加拿大

在中外高等教育中,"微积分"都是一门重要的基础课程,只是根据学生专业的不同,对这门课程要求修读的深浅层次有所差异而已。本文在对加拿大布兰登大学微积分教学的实地体验和研究中,特别关注到该校微积分教学中的过程学习和考核两个方面... 详细信息

在中外高等教育中,"微积分"都是一门重要的基础课程,只是根据学生专业的不同,对这门课程要求修读的深浅层次有所差异而已。本文在对加拿大布兰登大学微积分教学的实地体验和研究中,特别关注到该校微积分教学中的过程学习和考核两个方面,并对比我校的高等数学课程教学,给出了值得借鉴的布兰登大学微积分教学实践和经验。

关键词：微积分课程过程考核形成性评价布兰登大学教学

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