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Audit of Neonatal Jaundice as Experienced at a Mission Hospital in Western Nigeria

Open Journal of Pediatrics 2024年第1期14卷 50-62页

作者： joel-medewase victor idowu Department of Paediatrics and Child Health Ladoke Akintola University of Technology Ogbomoso Nigeria

Introduction: Neonatal jaundice (NNJ) is a common disorder in neonates that can impact negatively on the brain and cause death. The peculiarities in aetiology and solutions for different settings are a knowledge gap. This informed the desire to determine local aetiology and solutions for neonatal jaundice in a missionary hospital in Abeokuta, Southwestern Nigeria. Methods: Consecutive consenting babies diagnosed with significant neonatal jaundice were studied between July 2016 and June 2019. Institutional ethical consent was obtained. A proforma was used to obtain socio-demographic data and other relevant information such as age, sex, birthweight, gestational age and history regarding the jaundice. All the information obtained was inputted into a computer and analysed with SPSS version 16. Results: A total of 179 babies with neonatal jaundice comprising of 120 (67.0%) boys and 59 (33.0%) girls with ages ranging between 1 and 12 days (mean 2.7 ± 2.9) were studied. Prematurity, ABO incompatibility, neonatal sepsis and glucose-6-phosphate enzyme deficiency accounted for over 80% of the causes of significant NNJ. Sixty (33.5%) of the 179 babies studied developed acute bilirubin encephalopathy and 11 (6.1%) mortalities were recorded. Higher proportions of babies that were out-born with spontaneous vaginal delivery modes had acute bilirubin encephalopathy (p < 0.05). Mothers with formal education had better outcome compared to mothers without, in terms of mortalities (p < 0.05). Conclusion: Neonatal jaundice is still a significant cause of morbidity and mortality in the neonatal age group. Maternal education is key to good outcome in neonatal jaundice.

关键词： Jaundice Neonates Bilirubinaemia Encephalopathy and Outcomes

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Congenital Bilateral Proximal Radio-Ulnar Synostosis in a Nigerian Child

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Open Journal of Pediatrics 2024年第1期14卷 101-107页

作者： Alabi Ayobami Oyetunji joel-medewase victor idowu Olalere Ayankemi Adenike joel Iretiayo Titilolu Sayomi Bukola Adetutu Oladibu Olanike Taiye Adetoye Mayowa Mary Ashaolu Oluwakayode Joseph Department of Paediatrics and Child Health Ladoke Akintola University of Technology Ogbomoso Nigeria Department of Radiology Ladoke Akintola University of Technology Ogbomoso Nigeria Department of Radiology University College Hospital Ibadan Nigeria Department of Paediatrics and Child Health LAUTECH Teaching Hospital Ogbomoso Nigeria

Congenital radio-ulnar synostosis (CRUS) is a rare skeletal malformation of the upper limb and the most common congenital functional disorder of the elbow joint, causing limitation in forearm rotational movements, which may lead to difficulties with some activities of daily living. We reported a 4-year-old girl with congenital bilateral proximal radio-ulnar synostosis who presented with functional discomfort due to limitation of the prono-supination movements of the forearms and abnormal gestures when handling objects. She has clinical and radiological features of congenital radio-ulnar synostosis (CRUS). However, the parents declined corrective surgery because of wrong perception of the condition to be normal. This case highlighted the poor health seeking behavior and wrong illness perception prevalent in the developing countries.

关键词： Congenital Radio-Ulnar Synostosis Upper Limb Congenital Anomalies Pro-no-Supination

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Beverage intake preference and bowel preparation laxative taste preference for colonoscopy

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2015年第3期6卷 84-88页

作者： Adeyinka O Laiyemo Clinton Burnside Maryam A Laiyemo John Kwagyan Carla D Williams Kolapo A idowu Hassan Ashktorab Angesom Kibreab victor F Scott Andrew K Sanderson Department of Medicine Howard University College of Medicine Howard University Cancer Center Department of Biological Sciences College of Arts and Sciences Howard University Georgetown-Howard Universities Center for Clinical and Translations Science

AIM: To examine whether non-alcoholic beverage intake preferences can guide polyethylene glycol(PEG)-based bowel laxative preparation selection for ***: We conducted eight public taste test sessions using commercially procured(A) unflavored PEG,(B) citrus flavored PEG and(C) PEG with ascorbate(Moviprep). We collected characteristics of volunteers including their beverage intake preferences. The volunteers tasted the laxatives in randomly assigned orders and ranked the laxatives as 1st, 2nd, and 3rd based on their taste preferences. Our primary outcome is the number of 1st place rankings for each preparation. RESULTS: A total of 777 volunteers completed the study. Unflavored PEG was ranked as 1st by 70(9.0%), flavored PEG by 534(68.7%) and PEG with ascorbate by173(22.3%) volunteers. Demographic, lifestyle characteristics and beverage intake patterns for coffee, tea, and carbonated drinks did not predict PEG-based laxative ***: Beverage intake pattern was not a useful guide for PEG-based laxative preference. It is important to develop more tolerable and affordable bowel preparation laxatives for colonoscopy. Also, patients should taste their PEG solution with and without flavoring before flavoring the entire gallon as this may give them more opportunity to pick a pattern that may be more tolerable.

关键词： Bowel preparation Laxatives Colonoscopy Taste tests Colon cancer Screening

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