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Cost-effectiveness of endoscopic ultrasound-guided coils plus cyanoacrylate injection compared to endoscopic cyanoacrylate injection in the management of gastric varices

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World Journal of Gastrointestinal Endoscopy 2021年第1期13卷 13-23页

作者： carlos Robles-Medranda joao Autran Nebel Miguel Puga-Tejada Roberto Oleas Jorge Baquerizo-Burgos Jesenia Ospina-Arboleda Manuel Valero Hannah Pitanga-Lukashok Gastroenterology and Endoscopy Division Instituto Ecuatoriano de Enfermedades DigestivasGuayaquil 090505GuayasEcuador

BACKGROUND Cyanoacrylate(CYA)injection can be performed using a standard upper endoscopy technique or under endoscopic ultrasound(EUS)guidance alone or in combination with *** is little information available on the economic impact of these treatment *** To compare the cost-effectiveness of treating gastric varices by CYA injection via upper endoscopy vs coils plus CYA guided by *** This was an observational,descriptive,and retrospective *** were allocated into two groups:A CYA group and coils plus CYA *** baseline characteristics were compared,and a cost analysis was *** Overall,36 patients were included(19 in the CYA group and 17 in the coils+CYA group).All patients in the CYA group had acute *** underwent a higher mean number of procedures(1.47 vs 1,P=0.025),and the mean volume of glue used was 2.15 vs 1.65 mL,P=*** coils+CYA group showed a higher technical success rate(100%vs 84.2%),with a complication rate similar to the CYA *** majority of CYA patients required hospitalization,and although the mean total per procedure cost was lower(United States$1350.29 vs United States$2978),the mean total treatment cost was significantly different(United States$11060.89 for CYA vs United States$3007.13 for coils+CYA,P=0.03).CONCLUSION The use of EUS-guided coils plus cyanoacrylate is more cost-effective than cyanoacrylate injection when the total costs are ***,randomized trials are needed to validate the cost-effectiveness of the EUS-guided approach to treat gastric varices.

关键词： Cost-effectiveness Endoscopic ultrasound-guided therapy Gastric varices Gastrointestinal bleeding Hemostasis Therapy

Evaluation of the Size and Location of the Genial Plexus,Related to Age,Sex and Dental Presence,in Implant Surgeries

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Journal of Biomedical Science and Engineering 2017年第10期10卷 456-465页

作者： joao Henrique Scotti Alerico Neuza Maria Souza Picorelli Assis carlos Eduardo Francischone Karina Lopes Devito Francisco Antoninho Alerico Bruno Salles Sotto-Maior Department of Implantology Sao Leopoldo Mandic Dental Research CenterSao LeopoldoBrazil Department of Dental Clinic Federal University of Juiz de ForaJuiz de ForaBrazil Department of Diagnosis Paranaense UniversityFrancisco BeltraoBrazil Department of Restorative Dentistry Federal University of Juiz de ForaJuiz de ForaBrazil

Generally being considered as a safe area for surgical approaches, the region between the mental foramina presents important anatomical structures. The objective of this study was to measure the dimensions of the genial plexus and its three-dimensional location in CBCT images, correlating the characteristics of this structure with dental presence, sex and age of patients. A total of 149 cone beam computer tomography (CBCT) scans of dentate (n = 74) and edentulous patients (n = 75) were selected, 59 male and 90 female, aged 18 - 86 years. Measurements of width and length of the genial canal were performed, and the shortest distances of the genial plexus were determined in relation to the alveolar bone crest, the buccal cortical bone and the base of the mandible. The results indicated significant differences between the dentate and edentulous groups for the mandibular canal length (p = 0.030), distance from alveolar crest (p < 0.001), and distance from buccal cortical bone (p < 0.001), with significantly higher values in dentate patients. As for gender, the distances between the genial plexus and the alveolar bone crest (p < 0.001) and the buccal cortical bone (p = 0.028) were significantly shorter for females. Regarding age, only the distance between the genial plexus and the alveolar crest showed a significant difference (p < 0.001), and the smallest values were measured in the older patients. It can be concluded that there are variations of the genial plexus in relation to gender, age and between edentulous and dentate patients. Therefore, the anterior region of the mandible, especially the midline should be observed with caution when undergoing surgical procedures, such as removal of bone grafts and installation of dental implants.

关键词： Genial Canal Cone-Beam Computed Tomography Dental Implants Measurement Paresthesia

Investigation of Galactic open cluster remnants： the case of NGC 7193

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Research in Astronomy and Astrophysics 2017年第1期17卷 31-54页

作者： Mateus de Souza Angelo joao Francisco Coelho dos Santos Jr Wagner Jose Barbosa Corradi Francisco Ferreira de Souza Maia Andres Eduardo Piatti Departamento de Fisica ICEx Universidade Federal de Minas Gerais Av. Antonio Carlos 6627 31270-901 Belo Horizonte MG Brazil Observatorio Astronomico Universidad Nacional de Cordoba Laprida 854 5000 Cordoba Argentina Consejo Nacional de Investigaciones Cientificas y Tecnicas Av. Rivadavia 1917 C1033AAJ Buenos AiresArgentina

Galactic open clusters （OCs） that survive the early gas-expulsion phase are gradually de- stroyed over time by the action of disruptive dynamical processes. Their final evolutionary stages are characterized by a poorly populated concentration of stars called an open cluster remnant （OCR）. This study is devoted to assessing the real physical nature of the OCR candidate NGC 7193. GMOS/Gemini spectroscopy of 53 stars in the inner target region were obtained to derive radial velocities and at- mospheric parameters. We also employed photometric and proper motion data. The analysis method consists of the following steps：（i） analysis of the statistical resemblance between the cluster and a set of field samples with respect to the sequences defined in color-magnitude diagrams （CMDs）; （ii） a 5-dimensional iterative exclusion routine was employed to identify outliers from kinematical and posi- tional data; （iii） isochrone fitting to thes× （J - Ks） CMD of the remaining stars and the dispersion of spectral types along empirical sequences in the （J - H） × （H - Ks） diagram were checked. A group of stars was identified for which the mean heliocentric distance is compatible with that obtained via isochrone fitting and whose metallicities are compatible with each other. Fifteen of the member stars observed spectroscopically were identified together with another 19 probable members. Our results indi- cate that NGC 7193 is a genuine OCR, of a once very populous OC, for which the following parameters were derived： d = 501±46 pc, t = 2.5±1.2 Gyr, （[Fe/H]） = -0.17±0.23 and E（B-V） = 0.05±0.05. Its luminosity and mass functions show depletion of low mass stars, confirming the OCR is in a dynam- ically evolved state.

关键词： open cluster remnants - Galactic open clusters

Clinical,Laboratory and Echografic Evaluation of Patients with Deep Vein Thrombosis Following Total Knee Arthroplasty

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Open Journal of Orthopedics 2019年第2期9卷 23-29页

作者： carlos Roberto Schwartsmann Mario Arthur Rockenbach Binz Marco Tonding Ferreira Felipe Roth Ivan Fadanelli Simionato Leandro de Freitas Spinelli joao Pedro Farina Brunelli Universidade Federal de Ciencias Medicas de Porto Alegre Porto AlegreBrazil Orthopaedics and Traumatology Service of the Santa Casa de Porto Alegre Hospitalar Complex Porto AlegreBrazil

Introduction: Total knee arthroplasty, being a major surgery, carries a risk of post-operative deep vein thrombosis (DVT). The main objective of the present study was to elucidate the association of clinical, laboratory, and echographic findings with the occurrence of DVT. Patients and Methods: The present study was prospective and non-randomized, with restricted exclusion criteria. Forty patients were submitted to total knee arthroplasty due to osteoarthritis. Patients were clinically evaluated by laboratory tests, assessment of pain and calf circumference, and the presence of Homans’ sign. Echo Doppler was performed in each patient on postoperative day 7. The echographic evaluation divided the patients into two groups: positive (G1) and negative for thrombosis (G2). All patients received prophylactic heparin during the 7-day hospital admission. Results: Eleven patients complained of pain (analgesic medication was used during the entire admission). Leg circumference variation from the pre-operative period to post-operative day 7 was: G1, 1.70 ± 1.12 cm and G2, 0.68 ± 1.25 cm (p = 0.03). Homans’ sign was considered positive in 10 patients. Echographic evaluation was positive in 11 patients (27.5%). No cases of pulmonary embolism, infection, or death were observed. Conclusions: The incidence of DVT was 27.5%, with an increase in leg circumference being the main predictive factor (p = 0.03).

关键词： Knee Arthroplasty DVT Knee Replacement

Total Knee Arthroplasty:Patellar Replacement’s Influence in Patient Quality of Life Postoperatively

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Open Journal of Orthopedics 2017年第8期7卷 228-234页

作者： carlos Roberto Schwartsmann Gabriel Severo da Silva Ivan Fadanelli Simionato Flavia Magalhaes Nunes Henrique Lammerhirt joao Pedro Farina Brunelli Leandro de Freitas Spinelli Federal University of Medical Sciences Porto AlegreBrazil Department of Orthopedics and Traumatology Irmandade Santa Casa de Misericordia de Porto AlegrePorto AlegreBrazil

Objective: To study the influence of patellar resurfacing on quality of life under a standardised score. The chosen score was the Knee Society Score (KSS), which considers range of motion, pain, contractors, alignment and stability. Methods: Retrospective review of 60 patients submitted to total knee arthroplasty (TKA) was divided into two groups: with patellar resurfacing (PR) and without patellar resurfacing (NPR). We reviewed data from these patients containing the KSS, which are routinely used in our service. Data were analysed from 2013 to 2014, with a minimal patient follow-up of 18 months. Results: There were no unsatisfactory scores in our study. Total scores (KSS) were similar between the groups (mean KSS: PR = 88.36 ± 9.64;NPR = 84.26 ± 9.44 [p = 0.1]). While stratifying into groups (poor, fair, good, excellent), we found excellent results in 84.8% of PR versus 59.3% NPR (p = 0.056). These data did not reach statistical significance and can therefore be considered a coincidental result. Conclusion: Although these results did not show statistical significance (p = 0.056), patellar resurfacing patients tend to get more “excellent” results after 18 months of follow-up in quality of life when evaluated by KSS. Perhaps a larger amount of patients would suffice to acquire statistical significance in a future study.

关键词： Knee Arthroplasty Patella Joint Instability Quality of Life

Organomineral Phosphorus Fertilization in the Production of Corn,Soybean and Bean Cultivated in Succession

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American Journal of Plant Sciences 2017年第10期8卷 2407-2421页

作者： Denize Carvalho Martins Alvaro Vilela De Resende joao carlos Cardoso Galvao Eduardo De Paula Simao José Paulo Da Costa Ferreira Gabriela De Oliveira Almeida Department of Plant Science Federal University of VicosaVicosaBrazil Embrapa Maize and Sorghum Sete LagoasBrazil Federal University of Sao joao Del Rei Sete LagoasBrazil

The use of organic waste in agriculture has been used aiming at greater productivity, decrease in the cost of production and sustainable use of resources. The present study aimed at evaluating the effect of phosphate fertilization with the maintenance of organomineral fertilizers, combining poultry manure and soluble or reactive phosphate, in the production of grains in corn culture and the residual effect for subsequent crops of beans and soybeans. The experiment was conducted in Sete Lagoas, MG, in 2015, using three fertilizers with sources of different phosphorus sources (triple super phosphate—STP, organomineral with STP and organomineral with Bayovar phosphate) applied at the doses of 65, 130, 195 and 260 kg·ha¯1 of P2O5 total, and compared to the control without phosphate fertilization. We evaluated the contents of foliar P, P accumulation in the grains, yields of corn grains, beans and soy, accumulated productivity and export of accumulated P of the three cultures. The three cultures assessed presented higher productivity when compared to the average of the factorial treatments that received phosphate fertilization relative to the control. Organomineral fertilizers increased grain production, obtaining average productivity equal to or greater than those obtained with the exclusive use of STP.

关键词： Reactive Phosphate Poultry Manure New Fertilizers

The importance of post-mortem examinations in cetacean biology:A report of a necropsy on Stenella coeruleoalba(Meyen,1833)(Cetacea:Delphinidae),from the Azores,Northeastern Atlantic

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Journal of Coastal Life Medicine 2016年第8期4卷 670-672页

作者： Mário César Sedrez joao de Avila Barcelos joao Pedro Barreiros Programa de Pós-Graduacao em Ecologia e Recursos Naturais Universidade Federal de São CarlosCP 676CEP:13565-905Sao CarlosSPBrazil Instituto Federal de Santa Catarina Jaraguádo SulCEP:89254-430SCSPBrazil Department of Agricultural Sciences Centre for EcologyEvolution and Environmental Changes/Azorean Biodiversity GroupUniversity of the Azores9700-042 Angra do HeroísmoPortugal Department of Agricultural Sciences Agricultural and Environmental Science and Technology Research CentreUniversity of the Azores9700-042 Angra do HeroísmoPortugal

This article reports the necropsy of a specimen of striped dolphin Stenella coeruleoalba found stranded in the north coast of Terceira Island,Azores,***,the importance of standard protocols in post-mortem examinations and the need to adequately proceed were *** marine mammals are valuable specimens for several studies of pathology and other veterinary medical *** the causa mortis was not determined,the full access to stranded specimens was crucial,not only for pathology studies but also for a proper training to veterinary medicine students whenever possible.

关键词： Strandings Cetacea Veterinary medicine Necropsy procedures Causa mortis

Antibody-Cytokeratin Marker 34βE12 in Prostate Cancer Detection

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Journal of Pharmacy and Pharmacology 2019年第4期7卷 187-197页

作者： Luiz carlos de Araújo Souza Vinícius Carvalhêdo Cunha Hugo Oliveira de Figueiredo Cavalcanti joao Ricardo Alves Sandra Lúcia Branco Mendes Coutinho Undergraduates of Medicine in the University Center of Brasilia(UniCEUB)and Researchers in the Department of Cytopathology and Pathological Anatomy of the Base Institute of the Federal District(NUCAP-IHBDF) Hospital Medical Sector Sul-Asa SulBrasilia 70330-150Brazil Resident Physician in Anatomical Pathology of the Federal District Base Institute(NUCAP-IHBDF) Hospital Medical Sector SulAsa SulBrasilia 70330-150Brazil Urologist Physician of the Clinical Body of the Federal District Base Institute and Urocentro(IHBDF) Hospital Medical Sector Sul-Asa SulBrasilia 70330-150Brazil Physician Anatomopathologist and Head of the Department of Cytopathology and Anatomical Pathology of the Federal District Base Institute(NUCAP-IHBDF) Hospital Medical Sector Sul-Asa SulBrasilia 70330-150Brazil

Introduction:The histological diagnosis of prostate cancer is commonly based on morphological *** presence of malignant tissue mixed with benign tissue,or the presence of carcinoma that mimics benignity may generate difficulty in the diagnostic ***,the application of immunohistochemistry contributes its diagnostic ***:To evaluate the 34βE12 marker in the detection of adenocarcinoma(ADn),atypical small acinar proliferation(ASAp),regular prostatic tissue(RPT)and regular prostatic tissue alternated by atrophy spotlights(RPTa)in transrectal biopsy guided by ultrasonography of patients with suspected prostate ***:Analysis of 34 patients who underwent ultrasound-guided transrectal biopsy with subsequent analysis by H&E staining and 34βE12 labeling for elucidation of neoplasms or diseased tissues with doubtful ***:The marker 34βE12 showed negativity in 100%of the neoplasms ADn,positivity in 100%of the benign prostatic tissues(RPT and RPTa);the patients with ASAp presented positivity(20%)and negativity(80%).The chi-square test(χ2)showed that there is an association(χ2=29.55 and p<0.0001)between the groups,that is,the 34βE12 marker has a significant value(p<0.0001)in the elucidation of patients with prostatic neoplasia and benign prostatic *** and Conclusion:With the early screening of prostate cancer in the modern era,pathologists have become increasingly challenged to diagnose small outbreaks of cancer when only a few atypical glands are present in transrectal biopsy-guided *** 34βE12 marker becomes an important tool in elucidating diagnoses such as ADn and ASAp.

关键词： Antibody-cytokeratin marker 34βE12 adenocarcinoma(ADn) atypical small acinar proliferation(ASAp) regular prostatic tissue(RPT) regular prostatic tissue alternated by atrophy spotlights(RPTa)

Group Analysis＂ Other Sights of the Conscious and the Unconscious

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Psychology Research 2015年第1期5卷 10-22页

作者： Abreu-Afonso Jose Dinis Cesar Ferreira Guilherme Sara Maria Caseiro Ferro Marques Paulo Motta Melo joao carlos Neto Isaura Porto Manuela Rodrigues Teresa Bastos Valente Aucindio Portuguese Group Analytic Society and Group Analytic Psychotherapy (SPG PAG) Lisbon Portugal