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Mechanical properties and corrosion behavior of selective laser melted 316L stainless steel after different heat treatment processes

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Journal of Materials Science & Technology 2019年第7期35卷 1499-1507页

作者： Decheng Kong Chaofang Dong Xiaoqing Ni Liang Zhang jizheng Yao Cheng Man xuequn Cheng Kui Xiao Xiaogang Li Beijing Advanced Innovation Center for Materials Genome Engineering Key Laboratory for Corrosion and Protection (MOE)Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083China Shanghai Engineering Research Center of 3D Printing Materials Shanghai Research Institute of MaterialsShanghai 200437China School of Materials Science and Engineering Ocean University of ChinaQingdao 266100China

Irregular grains, high interfacial stresses and anisotropic properties widely exist in 3D-printed metallic materials, and this paper investigated the effects of heat treatment on the microstructural, mechanical and corrosion properties of 316 L stainless steel fabricated by selective laser melting. Sub-grains and low-angle boundaries exist in the as-received selective laser melted(SLMed) 316 L stainless steel. After heat treatment at 1050℃, the sub-grains and low-angle boundaries changed slightly, and the stress state and strength decreased to some extent due to the decrease of dislocation density. After heat treatment at 1200℃, the grains became uniform, and the dislocation cells vanished, which led to a sharp decline in the hardness and strength. However, the ductility was improved after recrystallization heat *** passive film thickness and corrosion potential of the SLMed 316 L stainless steel decreased after heat treatment, and the pitting potential also decreased due to the accelerated transition from metastable to steady-state pitting;this accelerated transition was caused by the presence of weak passive films at the enlarged pores after heat treatment, especially for an adequate solid solution treatment.

关键词： 316L stainless steel Selective laser melting Heat treatment Microstructure Mechanical property Corrosion behaviour

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An Efficient Trap Passivator for Perovskite Solar Cells:Poly(propylene glycol)bis(2‑aminopropyl ether)

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Nano-Micro Letters 2020年第12期12卷 251-263页

作者： Ningli Chen Xiaohui Yi Jing Zhuang Yuanzhi Wei Yanyan Zhang Fuyi Wang Shaokui Cao Cheng Li jizheng Wang CAS Key Laboratory of Organic Solids Beijing National Laboratory for Molecular SciencesInstitute of Chemistry Chinese Academy of SciencesBeijing 100190People’s Republic of China University of Chinese Academy of Sciences Beijing 100190People’s Republic of China Department of Physics Xiamen UniversityXiamen 361005People’s Republic of China CAS Key Laboratory of Analytical Chemistry for Living Biosystems Beijing National Laboratory for Molecular SciencesInstitute of Chemistry Chinese Academy of SciencesBeijing 100190People’s Republic of China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450000People’s Republic of China

Perovskite solar cells(PSCs)are regarded as promising candidates for future renewable energy ***-density defects in the perovskite films,however,lead to unsatisfactory device ***,poly(propylene glycol)bis(2-aminopropyl ether)(PEA)additive is utilized to passivate the trap states in *** PEA molecules chemically interact with lead ions in perovskite,considerably passivate surface and bulk defects,which is in favor of charge transfer and ***,the PEA additive can efficiently block moisture and oxygen to prolong the device *** a result,PEA-treated MAPbI3(MA:CH3NH3)solar cells show increased power conversion efficiency(PCE)(from 17.18 to 18.87%)and good longterm *** PEA is introduced to(FAPbI3)1-x(MAPbBr3)x(FA:HC(NH2)2)solar cells,the PCE is enhanced from 19.66 to 21.60%.For both perovskites,their severe device hysteresis is efficiently relieved by PEA.

关键词： Defects Grain boundaries Passivation Stability Perovskite solar cells

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Erratum to:Emergence of charge density wave and Ising superconductivity in centrosymmetric monolayer 1T-HfTe_(2)

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Nano Research 2023年第8期16卷 11544-11544页

作者： Dawei Wang jizheng Wu Chen Si Department of Medical Engineering Medical Supplies Center of PLA General HospitalBeijing 100853China School of Materials Science and Engineering Beihang UniversityBeijing 100191China

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富营养化高原浅水湖泊持续多年生态修复工程效果分析——以滇池大泊口为例

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湖泊科学 2023年第5期35卷 1549-1561页

作者：华映肖潘继征杜劲松李杨杨齐徐双黄育红中国科学院南京地理与湖泊研究所湖泊与环境国家重点实验室南京210008 中国科学院大学北京100049 滇池湖泊生态系统云南省野外科学观测研究站昆明650228 昆明市滇池高原湖泊研究院昆明650228 苏州科技大学环境科学与工程学院苏州215009

大泊口位于滇池草海南部,水域面积0.52 km^(2),平均水深约2 m,作为滇池草海重富营养化水域生态修复示范区,大泊口分别于2015和2019年开展了两期生态修复工程,经过近年来的系统治理,大泊口水生态治理效果初步显现。为分析探究成功修复湖... 详细信息

大泊口位于滇池草海南部,水域面积0.52 km^(2),平均水深约2 m,作为滇池草海重富营养化水域生态修复示范区,大泊口分别于2015和2019年开展了两期生态修复工程,经过近年来的系统治理,大泊口水生态治理效果初步显现。为分析探究成功修复湖区水质改善、生态系统企稳向好的原因,本研究选择2015年2月—2021年12月共7年的连续监测数据,根据工程开展情况以及水生态状况将大泊口水域划分为4个部分(A1~A4水域),首先分析4个区域内主要的水质指标(悬浮物(SS)、化学需氧量(COD_(Cr))、总磷(TP)、总氮(TN)和叶绿素a(Chl.a))的变化趋势和相关性,其次探究不同类型生态工程的修复效果,最后与草海和外海水域进行对比,分析大泊口的治理效果。结果表明,治理后大泊口A1~A4水域的COD_(Cr)、TP和Chl.a稳定下降,COD_(Cr)分别降低18.65、27.96、25.26、40.92 mg/L,TP分别降低0.11、0.10、0.11、0.14mg/L,Chl.a分别降低0.037、0.068、0.067、0.106 mg/L,SS具有较强的季节性波动,TN仅有东南部A4水域表现出持续下降的趋势,平均下降0.68 mg/L。通过相关性分析得出,COD_(Cr)、TP与Chl.a的相关性最强,COD_(Cr)和TP可能是影响大泊口藻类生长的关键环境因子;大泊口开展的引水换水工程和微滤净化(除藻)工程,降低了营养盐浓度、加速了水体交换,进而降低了藻类生物量以及发生藻源性污染的风险,再通过沉水植物修复工程进一步净化水质,为形成稳定的草型湖泊提供条件,并且认为沉水植物修复工程是上述工程中最为直接、经济和长效的手段措施;最后将大泊口典型水域的水质和草海、外海水质进行比较,可以认为在相同的地理及气候条件下,大泊口东南水域的生态修复取得了一定的成功。大泊口部分湖区可作为重度富营养化藻型湖区成功修复的案例,其生态修复经验对于持续推进大泊口、草海甚至整个滇池的生态环境修复具有重要的借鉴和参考价值。

关键词：生态修复水质改善治理效果滇池大泊口

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异构智能网联汽车编队延迟补偿控制研究

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汽车工程 2023年第9期45卷 1573-1582页

作者：刘济铮王震坡孙逢春张雷北京理工大学机械与车辆学院北京100081 电动车辆国家工程技术研究中心北京100081

智能网联汽车多车编队行驶可有效缩短跟车间距和提升交通系统通行效率,但多车编队控制须解决异构编队控制器的普适性问题,且能够在执行器响应延迟和通讯延迟情况下保证车辆编队的弦稳定性。本文提出一种面向异构智能网联汽车编队的延迟... 详细信息

智能网联汽车多车编队行驶可有效缩短跟车间距和提升交通系统通行效率,但多车编队控制须解决异构编队控制器的普适性问题,且能够在执行器响应延迟和通讯延迟情况下保证车辆编队的弦稳定性。本文提出一种面向异构智能网联汽车编队的延迟补偿控制方法,在无须获取他车系统动力学参数及控制输入前提下,利用他车加速度信息即可实现车辆编队纵向跟踪控制;此外,提出一种基于Smith预测器的延迟补偿控制架构,分别消除和降低了执行器响应延迟和通讯延迟对车辆编队弦稳定性的影响。典型工况仿真结果表明,相较常见车辆编队控制方法,本文提出的异构车辆编队延迟补偿控制器的跟车误差降低了80.7%,有效减小了最小车头时距和跟车间距。

关键词：智能网联汽车异构车辆编队延迟补偿弦稳定性

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Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy

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Protein & Cell 2019年第3期10卷 178-195页

作者： Lin Cao jizheng Chen Yaxin Wang Yuting Yang Jie Qing Zihe Rao Xinwen Chen Zhiyong Lou College of Pharmacy&State Key Laboratory of Medicinal Chemical Biology Nankai UniversityTianjin 300071China National Laboratory of Macromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China State Key Laboratory of Virology Wuhan Institute of VirologyChinese Academy of SciencesWuhan 430071China School of Medicine and Collaborative Innovation Center of Biotherapy Tsinghua UniversityBeijing 100084China Beijing No.166 High School Beijing 100006China

Hepatitis C virus(HCV)is a leading cause of liver disease *** several HCV protease/polymerase inhibitors were recently approved by ***,the combination of antivirals targeting multiple processes of HCV lifecycle would optimize anti-HCV therapy and against potential *** entry is an essential target step for antiviral development,but FDA-approved HCV entry inhibitor remains *** we identify serotonin 2A receptor(5-HT2aR)is a HCV entry factor amendable to therapeutic intervention by a chemical biology *** silencing of 5-HT2aR and clinically available 5-HT2aR antagonist suppress cell culture-derived HCV(HCVcc)in different liver cells and primary human hepatocytes at late endocytosis *** mechanism is related to regulate the correct plasma membrane localization of claudin 1(CLDN1).Moreover,phenoxybenzamine(PBZ),an FDAapproved 5-HT2aR antagonist,inhibits all major HCV genotypes in vitro and displays synergy in combination with clinical used anti-HCV *** impact of PBZ on HCV genotype 2a is documented in immune-competent humanized transgenic *** results not only expand the understanding of HCV entry,but also present a promising target for the invention of HCV entry inhibitor.

关键词： HCV serotonin 2A receptor entry antiviral drug

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Arginine methylation of ribose-5-phosphate isomerase A senses glucose to promote human colorectal cancer cell survival

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Science China(Life Sciences) 2020年第9期63卷 1394-1405页

作者： jizheng Guo Qixiang Zhang Ying Su Xiaochen Lu Yiping Wang Miao Yin Weiguo Hu Wenyu Wen Qun-Ying Lei Department of Biochemistry and Molecular Biology School of Basic Medical ScienceShanghai Medical CollegeFudan UniversityShanghai 200032China Fudan University Shanghai Cancer Center Department of OncologyShanghai Medical CollegeFudan UniversityShanghai 200032China Institutes of Biomedical Sciences Shanghai Medical CollegeFudan UniversityShanghai 200032China State Key Laboratory of Medical Neurobiology Shanghai Medical College Fudan UniversityShanghai 200032China

Cancer cells remodel their metabolic network to adapt to variable nutrient availability. Pentose phosphate pathway(PPP) plays protective and biosynthetic roles by oxidizing glucose to generate reducing power and ribose. How cancer cells modulate PPP activity in response to glucose supply remains unclear. Here we show that ribose-5-phosphate isomerase A(RPIA), an enzyme in PPP, directly interacts with co-activator associated arginine methyltransferase 1(CARM1) and is methylated at arginine 42(R42). R42 methylation up-regulates the catalytic activity of RPIA. Furthermore, glucose deprivation strengthens the binding of CARM1 with RPIA to induce R42 hypermethylation. Insufficient glucose supply links to RPIA hypermethylation at R42, which increases oxidative PPP flux. RPIA methylation supports ROS clearance by enhancing NADPH production and fuels nucleic acid synthesis by increasing ribose supply. Importantly, RPIA methylation at R42 significantly potentiates colorectal cancer cell survival under glucose starvation. Collectively, RPIA methylation connects glucose availability to nucleotide synthesis and redox homeostasis.

关键词： ribose-5-phosphate isomerase A CARM1 arginine methylation pentose phosphate pathway ribulose-5-phosphate reactive oxygen species colorectal cancer

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Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients

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Signal Transduction and Targeted Therapy 2021年第9期6卷 2822-2830页

作者： Yanbo Wang Xiaoju Zhu Xia-Ming Jiang Jingwei Guo Zheng Fu Zhen Zhou Ping Yang Hongyuan Guo xu Guo Gaoli Liang Ping Zeng Gengfu Xiao jizheng Ma Xin Yin Lei-Ke Zhang Chao Yan Chen-Yu Zhang Nanjing Drum Tower Hospital Center of Molecular Diagnostic and Therapy Chinese Academy of Medical Sciences Research Unit of Extracellular RNAState Key Laboratory of Pharmaceutical BiotechnologyJiangsu Engineering Research Center for MicroRNA Biology and BiotechnologyNJU Advanced Institute of Life Sciences(NAILS)NJU Institute of Al Biomedicine and BiotechnologyChemistry and Biomedicine Innovation Center(ChemBIC)School of Life SciencesNanjing UniversityNanjingChina State Key Laboratory of Virology Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhanHubeiChina Department of Clinical Laboratory The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjingChina The MOH Key Laboratory of Geriatrics Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijingChina The Research Center of Military Exercise Science The Army Engineering University of PLANanjingJiangsuChina

Elderly people and patients with comorbidities are at higher risk of COVID-19 infection,resulting in severe complications and high ***,the underlying mechanisms are *** this study,we investigate whether miRNAs in serum exosomes can exert antiviral functions and affect the response to COVID-19 in the elderly and people with diabetes.

关键词： patients mortality infection

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运动与肌肉——大脑间的交流

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体育科技文献通报 2022年第5期30卷 254-258页

作者：徐琳马继政江苏省司法警官高等职业学校江苏镇江212000 中国人民解放军陆军工程大学军事运动科学研究中心江苏南京211101

运动对大脑健康有许多有益的影响,例如有助于降低痴呆、抑郁和压力的风险,它在维持和恢复认知功能、代谢控制等方面有积极作用。运动被大脑感知的事实表明,肌肉诱发的周边因素使肌肉和大脑功能之间存在直接的相互影响。机体在运动后骨... 详细信息

运动对大脑健康有许多有益的影响,例如有助于降低痴呆、抑郁和压力的风险,它在维持和恢复认知功能、代谢控制等方面有积极作用。运动被大脑感知的事实表明,肌肉诱发的周边因素使肌肉和大脑功能之间存在直接的相互影响。机体在运动后骨骼肌能够分泌肌肉因子,这些肌肉因子可以直接或通过改变脑源性神经营养因子(Brain-derived neurotrophic factor,BDNF)蛋白水平来影响海马功能。越来越多的证据表明,肌肉因子组织蛋白酶B(Cathepsin B,CTSB)可以通过血脑屏障,增强BDNF的产生,从而促进神经发生、记忆和学习。同时,运动也增加了纤维连接蛋白III型结构域蛋白5(Fibronectin typeⅢdomain protein 5,FNDC5)的神经元基因表达,同样有助于增加大脑中BDNF的水平。运动还增加了依赖过氧化物酶体增殖物激活受体-γ辅助调节因子-1α(Peroxisome proliferator-activated receptor-γcoactlvator-1α,PGC-1α)的犬尿氨酸转氨酶的肌肉表达,从而诱导神经毒性犬尿氨酸和神经保护犬尿氨酸之间的平衡发生有益的转变,从而减轻类似抑郁的症状。本文回顾了一些肌肉因子对脑功能影响的诸多证据,肌肉因子的存在增强了对肌肉与大脑之间有效沟通的理解,从而更好地了解运动锻炼在整个机体水平上发挥有益作用。

关键词：脑源性神经营养因子纤维连接蛋白III型结构域蛋白5 组织蛋白酶B

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Seasonal dynamic changes in bacterial compositions in the Inner Mongolia desert steppe

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Frontiers in Biology 2009年第2期4卷 187-191页

作者： Ping LU Wanli MA Hao LI Yongsheng WU Guifen LV jizheng HE College of Life Science and Technology Inner Mongolia Normal UniversityHuhhot 010022China Research Center of Ecology and Environment Chinese Academy of SciencesBeijing 100083China Planning and Design Academy of Forestry Products Industry State Forestry AdministrationBeijing 100714China

Polymerase chain reaction-denaturing gradient gel electrophoresis(PCR-DGGE)technique was employed to examine the seasonal dynamic changes in bacterial community composition in the Inner Mongolia desert steppe using specific primers F954 and *** and reproducible bands were sequenced,and the phylogenic tree was *** results show that the bacterial community composition changed between different *** specific bands were different between the sampling sites with light and heavy levels of degraded *** main types of bacteria constituting the microbial community in the Inner Mongolia desert steppe belonged to the α,γ and δ-sub phyla of Proteobacteria,Bacteroidetes and *** unculturable bacteria accounted for 69%of the whole bacterial community of the Inner Mongolia desert steppe.

关键词： Polymerase chain reaction-denaturing gradient gel electrophoresis(PCR-DGGE) Inner Mongolia desert steppe community composition seasonal dynamic change

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