检索结果-南通市图书馆

稀有金属材料与工程 2006年第A03期35卷 270-273页

作者： Nongyue He Yuanying zhang jinan zhang State Key Laboratory of Bioelectronics Southeast University Nanjing 210096 China Jiangsu Cancer Hospital Nanjing 210007 China Research Institute of Cardiovascular Disease First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China

Hypertrophic cardiomyopathy (HCM) is one of the diseases damaging people health most badly and some mutations of exons in cardiac troponin I (cTnI) gene are closely associated with family hypertrophic cardiomyopathy (FHCM).A microarray was fabricated to screen mutations in exons 3,5,7,and 8 in cTnI *** were designed for the PCR (polymerase chain reaction) to amplify the target DNA fragments from fresh blood *** order to simplify the PCR process,multiplex PCR technology was investigated in *** concentration of Mg^(2+) played an important role in multiplex PCR process,a properly low concentration of Mg^(2+) submitted a better speciality of PCR *** speciality was also favored when the annealing temperature was reasonably enhanced and 64℃is the optimal annealing temperature for the multiplex PCR *** applying the fabricated gene-chip to detect the target fragments from PCR mixture,the signal intensity sequence is in accordance with that from theoretic estimate.

关键词： hypertrophic cardiomyopathy(HCM) gene-chip multiplex PCR mutation hybridization

Proteomic analysis of urinary exosomes reveals ferroptosis-associated proteins are involved in diabetic nephropathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第5期11卷 6-8页

作者： Kaida Mu Yanping Yang Xiaofei An Jie Zhu Jing zhang Yanfei Jiang Xiaorong Yang jinan zhang Department of Endocrinology and Metabolism Shanghai University of Medicine&Health Sciences Affiliated Zhoupu HospitalShanghai 201318China Department of Endocrinology Affiliated Hospital of Nanjing University of Chinese MedicineNanjingJiangsu 210029China

Diabetic nephropathy(DN)is one of the major microvascular complications of diabetes mellitus and a major cause of end-stage renal disease(ESRD).The pathogenesis of DN is unknown,but it is closely related to disorders of glucolipid metabolism,abnormal hemodynamics,chronic inflammatory response,oxidative stress,and *** DN develops into ESRD,it is often more difficult to treat than ESRD caused by other kidney ***,a deeper knowledge of the pathophysiological mechanisms of DN and the discovery of candidate markers for early diagnosis are *** secreted by renal cells can regulate a series of pathophysiological processes such as translation and transcription by releasing miRNAs or proteins,thereby regulating the biological functions and phenotype of recipient kidney *** has been found that miRNA secreted by urinary exosomes in patients with DN is involved in the occurrence and development of DN and may become biological markers.1 However,studies on exosome proteins are relatively few and lack validation in *** the present study,we identified an altered pathway in urinary exosomes from DN patients for the first ***,the altered ferroptosis-related proteins may represent novel candidate markers for early progression of disease and/or early treatment effects.

关键词： urinary metabolism diagnosis

Study on activated carbon in chromium-containingwastewater treatment by XPS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 1994年第2期6卷 173-179页

作者： Yang Jun Wang Yunxiu(Shandong University of Technology,jinan 250014, China)zhang Yinsheng(Shandong Non-Metallic Material Research Institute,jinan 250014, China)

The mechanism of activated carbon treatment with chromium-containing wastewater byX-ray photoelectron spectroscopy (XPS) and that of adsorption and reduction reaction of the acti-vated carbon with hexavalent chromium solution are presented in this paper. The XPS results showthat at PH6,the main process is adsorption of the car-bon to Cr(VI). The optimum range of treatment is at pH 3-6,in which removal efficiency ofadsorption and reduction is relatively high. It demonstrates that the reduction mechanism is aheterogeneous acid catalysis process.

关键词： wastewater treatment X-ray photoelectron spectrometry activated carbon.

Embarking on a New Journey Toward High-Quality Social Security

在线全文

学校读者我要写书评

暂无评论

Qiu Shi 2021年第4期13卷 61-70页

作者： zhang jinan CPC Leadership Group of Ministry of Human Resources and Social Security

In his speech to the 28th group study session of the Communist Party of China(CPC)Central Committee Political Bureau,General Secretary Xi Jinping emphasized that social security is a fundamental institutional guarante... 详细信息

关键词： ping guarantee fairness

Pushing for Fuller md Higher Quality Employment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Qiu Shi 2018年第4期10卷 99-103页

作者： zhang jinan Resources and Social Security of the People's Republic of China

*** new landscape facing employment The Chinese government is committed to a strategy that puts employ-ment *** has implemented proactive employment policies and made a series of relevant decisions and *** results have been achieved through these efforts,with employment continuing to expand and constant optimization taking place in the employment structure.

关键词： Employment Chinese government

A COUPLED THERMO-HYDRAULIC MODEL FOR STEAM FLOW IN PIPE NETWORKS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2009年第6期21卷 861-866页

作者： LIU Qing-tang zhang Zeng-gang PAN Ji-hong GUO Jing-qiang School of Energy Source and Power Engineering Shandong University Jinan 250061 China School of Thermal Power Engineering Shandong Jianzhu University Jinan 250101 China Yishui Municipal Engineering Co. Yishui 276400 China

This article aims to establish a coupled thermo-hydraulic mathematical model for steam network by adopting a set of equations, i.e., the continuity equation, motion equation, energy equation, state equation and enthalpy equation and considering the interaction of hydraulic and thermal working conditions. The model is simplified according to steam flow features in pipe networks. The unsteady flow model is simplified to a steady one with considering engineering practice and the solution to the governing equations are obtained by using the standard fourth-order Runge-Kutta method. Many factors of steam flow are generally considered, such as condensability, change of state, friction and heat transfer in the model. It is concluded that coupled iteration can be employed in steam network thermo-hydraulic computation. The numerical results with the model are basically in accordance with practical operation data.

关键词： steam flow thermo-hydraulic coupling mathematical model hydraulic calculation

Preliminary studies on the characteristics of growth of released prawn, Penaeus orientalis Kishinouye, for reproduction in middle Huanghai Sea fishing ground

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 1992年第1期11卷 145-151页

作者： Chen ZongyaoShandong Fisheries Bureau, jinan, ChinaLiu Yongchang, zhang Yunshang Gao Yongf uMarine Fisheries Research Institute of Shandong, Yantai, Chaa

The growing demand of prawn protein in the world has been demanding an increasing catch of prawn from the sea which, however, fails to meet the needs due to over exploitation. This ease has always been a keen subject among us fishery seientists. With the support and guidance of the Provincial Government of Shandong, the Shandong Fishery Bureau has been carrying out a project of "the Ex-

关键词： Penaeus orientalis Kishinouye for reproduction in middle Huanghai Sea fishing ground

Studies on the Phase Behavior of Lyotropic Liquid Crystal in DAD/C_4OH/n-C_8H_(18)/D_2O System

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1997年第9期8卷 821-824页

作者： Qiang SHEN Gan Zuo LI Cheng Song MA(Institute of Colloid Interface. Shandong University,jinan,250100)Yan zhang HUANG(Institute of Mechanics of Fluids in Porous Medium, Chinese Academy of Science, Langfang. 065007) SHANDONG UNIV INST COLLOID INTERFACEJINAN 250100PEOPLES R CHINA CHINESE ACAD SCI INST MECH FLUIDS POROUS MEDLANGFANG 065007PEOPLES R CHINA

The lytropic liquid crystals in dodecanic acid diethanolamine (DAD) /n-butanol (C4OH) /octane (n-C8H18) /deuteron (D2O) system were studied to determine the phase regions and were investigated by 2H-NMR spectroscopy,optical polarizing microscope and small-angle X-ray diffraction (SAXD) *** results indicate that the lamellar,hexagonal and cubic liquid crystals all exist in the above *** the weight ratio of DAD and C4OH constant,the microphase Structure,2H quadruple splitting and the interlayer spacing are all changed with the addition of deuteron.

关键词： OH Studies on the Phase Behavior of Lyotropic Liquid Crystal in DAD/C4OH/n-C8H DAD D2O System

ON SOME RESULTS OF YI AND THEIR APPLICATIONS IN THE FUNCTIONAL EQUATIONS

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Scientia 2010年第5期30卷 1649-1660页

作者：杨连中张继龙 School of Mathematics and System Sciences Shandong University LMIB and School of Mathematics and System Sciences Beihang University

In this article, we establish some uniqueness theorems that improves some results of H. X. Yi for a family of meromorphic functions, and as applications, we give some results about the non-existence of meromorphic sol... 详细信息

关键词： functional equations meromorphic functions uniqueness

在线全文

学校读者我要写书评

暂无评论

师范生心理素质评价量表的研制

心理科学 2004年第2期27卷 453-455页

作者：张景焕张承芬常淑敏北京师范大学心理学院北京100875 济南大学济南250022 山东师范大学教科院济南250014

该研究在前期研究的基础上,经进一步理论分析,初步编制了由责任感、有恒性、客观性、非权势性、创造性、监控性、教育效能感、角色认同、成就动机9个分量表构成的“师范生心理素质评价量表”。经项目分析、预测、非正式测量确定了量表... 详细信息

该研究在前期研究的基础上,经进一步理论分析,初步编制了由责任感、有恒性、客观性、非权势性、创造性、监控性、教育效能感、角色认同、成就动机9个分量表构成的“师范生心理素质评价量表”。经项目分析、预测、非正式测量确定了量表的具体测验题。对976名师范生正式测量结果的分析表明。该量表有较高的信度和效度,能够较好地评定师范生的心理素质,对优秀教师与一般教师亦有一定的区分鉴别作用。在文章的最后,作者进一步讨论了师范生心理素质及其结构。

关键词：师范生心理素质量表信度效度测量结果效度