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Fabrication of cast carbon steel with ultrafine TiC particles

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 54-57页

作者： Sang-Hoon LEE jin-ju park Sung-Mo HONG Byoung-Sun HAN Min-Ku LEE Chang-Kyu RHEE Nuclear Materials Research Division Korea Atomic Energy Research Institute Daejeon 305-353 Korea

The carbon steels dispersed with ultrafine TiC particles were fabricated by conventional casting method. The casting process is more economical than other available routes for metal matrix composite production, and the large sized components to be fabricated in short processing time. However, it is extremely difficult to obtain uniform dispersion of ultrafine ceramic particles in liquid metals due to the poor wettability and the specific gravity difference between the ceramic particle and metal matrix. In order to solve these problems, the mechanical milling (MM) and surface-active processes were introduced. As a result, Cu coated ultrafine TiC powders made by MM process using high energy ball milling machine were mixed with Sn powders as a surfactant to get better wettability by lowering the surface tension of carbon steel melt. The microstructural investigations by OM show that ultrafine TiC particles are distributed uniformly in carbon steel matrix. The grain sizes of the cast matrix with ultrafine TiC particles are much smaller than those without ultrafine TiC particles. This is probably due to the fact that TiC particles act as nucleation sites during solidification. The wear resistance of cast carbon steel composites added with MMed TiC/Cu-Sn powders is improved due to grain size refinement.

关键词： TiC particles mechanical milling carbon steel casting dispersion wettability

Inhibition of advanced glycation endproducts formation by Korean thistle,Cirsium maackii

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Asian Pacific Journal of Tropical Medicine 2015年第1期8卷 1-5页

作者： Hyun Ah jung jin ju park Byung Sun Min Hee jin jung Md.Nurul Islam Jae Sue Choi Department of Food Science and Human Nutrition Chonbuk National University Department of Food and Life Science Pukyong National University College of Pharmacy Catholic University of Daegu

Objective:To evaluate inhibitoy potential of seven Korean thistles against the advanced glyeatinn endproducts(AGE) formation as well as to identify responsible compounds from the most active ***:We used an in vitro AGE inhibition assay to evaluate the antidiabetic complication potential of the methanol extracts of the selected Korean ***:Among the seven Korean thistles,the leaves of Cirsium maackii(***) exhibited the most significant inhibitory activity against AGE *** means of bioassay-directed fractionation,a *** acid and 14 flavonoids were isolated from the active ethyl acetate soluble fraction of a methanol extract from *** *** and its 5-O-glueoside have been previously isolated:however,a lignan and 13 known compounds were isolated for the first lime from C maackii leaves in this *** of the isolated compounds exhibited inhibitory activities against potential AGE *** them,cernuoside was shown to be the most potent AGE inhibitor with an IC_(50) value of 21.21 μ mol/*** importantly,two major flavonoids,luteolin and ils 5-O-glucoside,also significantly inhibited AGE formation,with IC_(50) values of36.33 and 37.47 μmol/L,*** activity relationship revealed that the presence of free 3'and 4' dihydroxyl group in flavonoids skeleton played an important role in AGE ***:These results indicate that *** and C maackii-derived flavonoids might be explored further to develop therapeutic agents for the prevention of diabetic eoniplicalions due to their significant inhibitory activity against AGE formation.

关键词： Flavonoids Thistle Advanced glycation endproducts Diabetic complications Cirsium maackii

Formation of interfacial brittle phases sigma phase and IMC in hybrid titanium-to-stainless steel joint

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 7-11页

作者： Min Ku LEE jung Gu LEE Jong Keuk LEE Sung Mo HONG Sang Hoon LEE jin ju park Jae Woo KIM Chang Kyu RHEE Nuclear Materials Research Division Korea Atomic Energy Research Institute Daejeon 305-353 Korea

The microstructures of the brazed joints for commercially pure Ti and stainless steel were investigated by the applications of various filler alloys including Ag-, Ti-, Zr- and Ni-based alloys. Generally, the dissimilar joints between Ti and stainless steel were dominated by the Ti-based intermetallic compounds （IMCs）, e.g. （Ti, Zr）2（Fe, Ni）, TiFe, TiCu, and Ti2（Fe, Ni）, due to a significant dissolution of Ti from the base metal. The （Fe-Cr） cr phase was also observed near the stainless steel due to a segregation of Cr into the interface region. This research demonstrates empirically that the brittleness of the Ti and stainless steel joint can not be avoided only by applying single braze alloy or single insert metal, and thus an introduction of additional suitable interlayer between the filler alloy and the base metal is necessary to prevent the brittleness of the joint.

关键词： brazing titanium stainless steel intermetallic compounds (IMCs)

Polyherbal formula SC-E3 inhibits rheumatoid arthritis activity in a mouse model of type-Ⅱcollagen-induced arthritis

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Journal of Integrative Medicine 2021年第3期19卷 265-273页

作者： ju-Yeon park Young-Won Kwon Sun-Ah Kim Sun-Dong park Chang-Hyun Kim jin-Hee Kim ju-Hee Lee College of Korean Medicine Dongguk UniversityGoyang 10326Republic of Korea Department of Medicine College of MedicineDongguk UniversityGoyang 10326Republic of Korea Department of Biomedical Laboratory Science College of Health ScienceCheongju UniversityCheongju 28503Republic of Korea

Objective:SC-E3 is a polyherbal formula that contains five medicinal herbs used frequently in traditional herbal *** our previous study,we demonstrated the antioxidant and anti-inflammatory effects of *** present study examined the effects of SC-E3 in a mouse model of type-II collagen-induced arthritis(CIA).Methods:In vivo,male DBA/1 J mice were immunized by intradermal injection of bovine type-II collagen and complete or incomplete Freund’s adjuvant,to induce ***-E3 was orally administered daily for 23 *** vitro,bone marrow-derived macrophages(BMMs)were treated with macrophage colony-stimulating factor(M-CSF)and receptor activator of nuclear factor-j B ligand(RANKL)in the absence or presence of ***:Administrations of SC-E3 were found to have anti-arthritic effects in the joints of CIA mice,as evidenced by reduced paw swelling,bone erosion and deformation,inflammatory cell infiltration,and inflammation in synovial ***-E3 also reduced serum levels of tumor necrosis factor-a,interleukin-1 b,aspartate aminotransferase and alanine ***,tartrateresistant acid phosphatase-positive osteoclast numbers in the joints were significantly lower in SC-E3-treated CIA mice than in CIA *** addition,the differentiations of BMMs to multinucleated osteoclasts induced by M-CSF and RANKL stimulation were dose-dependently reduced by ***:These results suggest that SC-E3 possesses substantial anti-arthritic activity because it inhibits pro-inflammatory cytokines and osteoclastogenesis,and that SC-E3 has potential therapeutic use for the treatment of rheumatoid arthritis.

关键词： Herbal formula Anti-inflammatory Rheumatoid arthritis Collagen-induced arthritis Osteoclastogenesis

Biochar improves soil properties and corn productivity under drought conditions in South Korea

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Biochar 2023年第1期5卷 1148-1158页

作者： Jae-Hyuk park jin-ju Yun Seong-Heon Kim Jong-Hwan park Bharat Sharma Acharya ju-Sik Cho Se-Won Kang Department of Agricultural Chemistry Sunchon National UniversitySuncheon 57922Republic of Korea Division of Soil and Fertilizer National Institute of Agricultural SciencesRDAWanju 55365Republic of Korea Department of Life Resources Industry Dong-A UniversityBusan 49315Republic of Korea Rodale Institute Southeast Organic CenterChattahoochee HillsGA 30268USA Department of Agricultural Life Sciences Sunchon National UniversitySuncheon 57922Republic of Korea

Biochar has been shown to improve soil properties and plant productivity in soils with inherently low ***,little has been reported for upland corns under dry and wet precipitation *** study investigates the effect of biochar addition on a range of soil physicochemical,biological,and hydrological properties,and corn growth and productivity under agrometeorological drought and wet ***,experiments were laid out in a randomized complete block design with three replications at two sites during 2017 and 2018 in South *** included(i)CN:control(ii)IF:inorganic fertilizer(N-P-K)at 145-30-60 kg ha^(−1);(iii)BS:barley straw at 5 t ha^(−1);(iv)CWBC:corn waste biochar at 5 t ha^(−1);(v)CWBC+IF:corn waste biochar+inorganic fertilizer;(vi)CWBC+BS:corn waste biochar+barley *** year 2017 was relatively dry,whereas the year 2018 was *** drought conditions in the year 2017,biochar facilitated soil water ***,higher precipitation in 2018 increased the quantity and distribution of soil water and nutrients in the top 15 *** reduced soil bulk density,and increased porosity,cation exchange capacity and total organic carbon in both years but increased total bacterial counts during the dry year *** population was generally higher under wet ***,more soil CO_(2) was emitted in the wet year than in the dry *** further indicated that biochar can enhance corn biomass and grain yield regardless of precipitation *** grain index was,however,affected by rainfall and was significantly different across treatments in the year 2018 *** biomass,grain yield,and grain index were highest in CWBC+IF treatment and lowest under CN ***,biochar addition appeared to improve soil quality and soil conditioning effects in the drought and wet years,ameliorating soil and plant ***,biochar can improve water and nutrients storage,availability,and uptake,and

关键词： Biochar Drought Precipitation Soil CO_(2)

Chorioretinal response to intravitreal aflibercept injection in acute central serous chorioretinopathy

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International Journal of Ophthalmology(English edition) 2019年第12期12卷 1865-1871页

作者： Byung ju jung Kook Lee jin Hyung park Jae Hyung Lee Department of Ophthalmology and Visual Science Seoul St.Mary’s Hospital College of Medicine the Catholic University of Korea

AIM: To evaluate chorioretinal responses to intravitreal aflibercept injection(IAI) in patients with acute central serous chorioretinopathy(CSC). METHODS: Seventy-one eyes from 71 patients with symptomatic CSC for less than six months were included. Thirty-five eyes received a single IAI and 36 eyes were observed without treatment. Best-corrected visual acuity(BCVA), central subfield foveal thickness(CSFT), and subfoveal choroidal thickness(SFCT) were assessed at baseline and at 1, 2, and 3 mo. RESULTS: The mean SFCT in the IAI group decreased at 1 mo, rebounded at 2 mo and remained stable at 3 mo compared to the baseline, while significant change was not noted in the observation group. The mean CSFT decreased significantly during the 3-month study period in both groups, and was significantly lower in the IAI group at 1 mo(P<0.001). A rebound of CSFT between 1 and 2 mo was noted in 14 eyes(40.0%) in the IAI group and in 1 eye(2.8%) in the observation group(P<0.001). The significant visual improvement was achieved from 1 mo in the IAI group, and from 2 mo in the observation group. The rate of complete absorption of subretinal fluid at 3 mo did not differ between the two groups.(45.7% vs 41.7%, P=0.813). CONCLUSION: A single IAI for acute CSC induce a transient decrease in SFCT and CSFT, which implies that IAI may have a pharmacological effect on the underlying hyperpermeable choroid in acute CSC.

关键词： aflibercept acute central serous chorioretinopathy anti-vascular endothelial growth factor choroidal hyperpermeability choroidal thickness

Behaviour of cold-formed stainless steel beams at elevated temperatures

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第11期9卷 1507-1513页

作者： ju CHEN Wei-liang jin Department of Civil Engineering Zhejiang University Hangzhou 310058 China

A study of the behaviour of constructional cold-formed stainless steel beams at elevated temperatures was conducted in this paper. An accurate finite element model (FEM) for stainless steel beams was developed using the finite element program ABAQUS. Stainless steel beams having different cross-sections were simulated in this study. The nonlinear FEM was verified against the experimental results. Generally, the developed FEM could accurately simulate the stainless steel beams. Based on the high temperature stainless steel material test results, a parametric study was carried out on stainless steel beams at elevated tem- peratures using the verified FEM. Both high strength stainless steel EN 1.4462 and normal strength stainless steel EN 1.4301 were considered. A total of 42 stainless steel beams were simulated in the parametric study. The effect of temperatures on the behaviour of stainless steel beams was investigated. In addition, a limiting temperature for stainless steel beams was also proposed.

关键词： Elevated temperatures Finite element model (FEM) Fire Stainless steel beams

Corner strength enhancement of high strength cold-formed steel at normal room and elevated temperatures

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第9期9卷 1251-1257页

作者： ju CHEN Wei-liang jin Department of Civil Engineering Zhejiang University Hangzhou 310027 China

In this study, the suitability of current design methods for the 0.2% proof yield strength of the comer regions for high strength cold-formed steel at normal room temperature was investigated. The current standard predictions are generally accurate for outer comer specimen but conservative for inner comer specimen. Based on the experimental results, an analytical model to predict the comer strength of high strength cold-formed steel at normal room temperature was also proposed. The comparison indicated that the proposed model predicted well the comer strength of high strength cold-formed steel not only at normal room temperature but also at elevated temperatures. It is shown that the predictions obtained from the proposed model agree well with the test results. Generally the comer strength enhancement of high strength cold-formed steel decreases when the temperature increases.

关键词： Cold-formed steel Comer Elevated temperatures High strength steel Yield strength

Fruits extracts of Hovenia dulcis *** lipopolysaccharide—stimulated inflammatory responses through nuclear factor—kappaB pathway in Raw 264.7 cells

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 349-355页

作者： ju-Yeon park jin-Young Moon Sun-Dong park Won-Hwan park Hyuck Kim Jai-Eun Kim Department of Acupoint College of Korean Medicine.Dongguk University Department of Prescription College of Korean MedicineDongguk University Department of Diagnostics College of Korean Medicine.Dongguk University Department of Pathology College of Korean Medicine.Dongguk University

Objective:To investigate the anti-inflammatory effects and the action mechanism of the fruits of Horenia dulcis(***) in lipopolysaccharide(LPS)-induced mouse macrophage Raw ***:The extract of *** fruits(EHDF) were extracted with 70%*** macrophages were treated with different concentrations of EHDF in the presence and absence of LPS(1 μg/mL).To demonstrate the inflammatory mediators including nitric oxide,inducible nitric oxide synthase and cyclooxygenase(COX)-2 expression levels were analyzed by usingin vitro assay ***-derived pro-inflammatory cytokines including interleukin-1 β.tumor necrosis factor- α and prostaglandin F_2 were determined using ELISA *** viability,heme oxygenase-1 expression,nuclear factor-kappaB and nuclear factor F.2-related factors 2 translocation were also ***:EHDF potently inhibited the LPS-stimulated nitric oxide,inducible nitric oxide ***-2,interleukin-1 β and tumor necrosis factor- α expression in a dose-dependent *** suppressed the phosphorylation of inhibited kappaB-alpha and p65 nuclear *** of macrophage cells with EHDF alone induced the heme oxygenase-1 and nuclear translocation of nuclear factor E2-reIated factor ***:These results suggest that the ethanol extract of *** fruit exerts its anti-inflammatory effects by inhibiting inhibited kappaBalpha phorylation and nuclear translocation of nuclear factor-kappaB.

关键词： Fruits of Hovenia dulcis Inflammation Macrophage Nuclear factor-kappaB Heme oxygenase-1