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Corrected-loss estimation for Error-in-Variable partially linear model

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Science China Mathematics 2015年第5期58卷 1101-1114页

作者： jin jiao TONG XingWei School of Statistics Beijing Normal University

We consider an Error-in-Variable partially linear model where the covariates of linear part are measured with error which follows a normal distribution with a known covariance matrix. We propose a corrected-loss estimation of the covariate effect. The proposed estimator is asymptotically normal. Simulation studies are presented to show that the proposed method performs well with finite samples, and the proposed method is applied to a real data set.

关键词： partially linear model Error-in-Variable robust analysis

高质量学前教育的内涵意蕴、突出指向与实践理路

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黑龙江教师发展学院学报 2025年第1期44卷 125-130页

作者：黄金姣袁昊杰陕西省听力语言康复中心西安710016 东北师范大学教育学部长春130024

党的二十大以来高质量学前教育成为时代的呼唤。对高质量学前教育的内涵意蕴进行梳理,发现其具备五大突出指向,即目标指向学前儿童的全面自由和谐发展;学理指向本土学前教育理论的开辟创新;实践指向各要素的扩优提质,交互协同;制度指向... 详细信息

党的二十大以来高质量学前教育成为时代的呼唤。对高质量学前教育的内涵意蕴进行梳理,发现其具备五大突出指向,即目标指向学前儿童的全面自由和谐发展;学理指向本土学前教育理论的开辟创新;实践指向各要素的扩优提质,交互协同;制度指向动态化的灵活调整,准确适切;价值指向满足人们美好幸福生活的需要。高质量学前教育的突出指向决定了其是一项系统性工程。基于系统论视角探索中国高质量学前教育的实践理路,应坚守儿童本位的立场,达成系统目标的统一;加强系统的开放交流,促进多元主体的协同;把握系统的扰动涨落,构建动态化支持体系;促进系统的竞争协同,激发系统的内生动力;推动系统的创新演变,开辟中国式发展道路。

关键词：高质量学前教育内涵意蕴突出指向实践理路

Identification of Protein Coding Regions of Rice Genes Using Alternative Spectral Rotation Measure and Linear Discriminant Analysis

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Genomics, Proteomics & Bioinformatics 2004年第3期2卷 167-173页

作者： jiao jin Department of Statistics and Financial Mathematics School of Mathematical SciencesBeijing Normal Uni-versityBeijing 100875 Beijing Genomics Institute Beijing 101300China

An improved method, called Alternative Spectral Rotation (ASR) measure, for predicting protein coding regions in rice DNA has been developed. The method is based on the Spectral Rotation (SR) measure proposed by Kotlar and Lavner, and its accuracy is higher than that of the SR measure and the Spectral Content (SC) measure proposed by Tiwari et al. In order to increase the identifying accuracy, we chose three di?erent coding characters, namely the asymmetric, purine, and stop-codon variables as parameters, and an approving result was presented by the method of Linear Discriminant Analysis (LDA).

关键词： Alternative Spectral Rotation measure DFT nonparametric fitting LDA

Temperature and thermodynamic deformation analysis of the rotors on a twin screw multiphase pump with high gas volume fractions

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第9期12卷 720-730页

作者： Tie-yu GAO Dong-fang YANG Feng CAO jin-cheng jiao School of Energy and Power Engineering Xi'an Jiaotong University Xi'an 710049 China

The pressure increasing process within a twin screw multiphase pump, under the condition of high gas volume fractions (GVFs), induces large temperature and pressure changes that cause the rotors to deform. Rotor deformations heavily influence the backflow of the multiphase fluid through clearances within the twin screw multiphase pump and these deformations may even lead to pump failures. An accurate temperature and pressure distribution on the screw rotors need be obtained before the deformation analysis can be carried out. By means of small temperature and pressure sensors embedded into the groove at the root of the rotors, the temperatures of 12 points on the rotors and the pressure distributions of a twin screw multiphase pump under high GVFs conditions were recorded. Temperature test results were adopted to perform a heat transfer analysis for determining the temperature distribution on the screw rotors. Then deformation analyses, including thermal deformation, force deformation, and total deformation, were conducted according to the pressure and temperature distributions. Deformation analysis for different materials was also conducted under the same boundary conditions. A material was suggested for the manufacturing of rotors in a twin screw multiphase pump under the condition of high gas volume fractions.

关键词： Multiphase pump Twin screw rotor Thermal deformation Finite element analysis

Two-dimensional particle-in-cell modeling of blow-off impulse by X-ray irradiation

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Nuclear Science and Techniques 2024年第3期35卷 53-69页

作者： Ruibo Li jin-Long jiao Hui Luo Dezhi Zhang Dengwang Wang Kai Wang Graduate School of China Academy of Engineering Physics Beijing 100193China Zhejiang Institute of Modern Physics Institute of AstronomySchool of PhysicsZhejiang UniversityHangzhou 310027China National Key Laboratory of Intense Pulsed Radiation Simulation and Effect Northwest Institute of Nuclear TechnologyXi’an 710024China

Space objects such as spacecraft or missiles may be exposed to intense X-rays in outer space,leading to severe *** reinforcement of these objects to reduce the damage caused by X-ray irradiation is a significant *** blow-off impulse(BOI)is a crucial physical quantity for investigating material damage induced by X-ray ***,the accurate calculation of BOI is challenging,particularly for large deformations of materials with complex *** this study,we develop a novel two-dimensional particle-in-cell code,Xablation2D,to calculate BOIs under far-field X-ray *** significantly reduces the dependence of the numerical simulation on the grid *** reliability of this code is verified by simulation results from open-source codes,and the calculated BOIs are consistent with the experimental and analytical results.

关键词： X-ray irradiation Energy deposition Blow-off impulse Particle in cells

Performance evaluation of new epoxy resin-based composite phase change materials and their asphalt mixture

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第3期11卷 507-522页

作者： Yuchao Gao jiao jin Shuai Liu Yinfei Du Guoping Qian Jie Mao Yongqiang Zhu School of Traffic and Transportation Engineering Changsha University of Science and TechnologyChangsha 410114China School of Civil Engineering Central South UniversityChangsha 410075China Guangdong Guanyue Highway and Bridge Co. Ltd.Guangzhou 511452China

In recent years,the temperature-adjusted asphalt pavement has been an extensive concern by scholars in various countries,and this pavement can reduce temperaturerelated *** this study,the shaped composite phase change materials(CPCMs)were successfully synthesized by two processes,which are vacuum impregnation and epoxy ***,the applicability of CPCMs in asphalt mixtures was evaluated by microscopic characterization,chemical compatibility,thermal properties,durability,and leakage ***,CPCMs were applied to the asphalt mixture to evaluate its temperatureadjusted characteristics and pavement ***,the performance of the temperature-adjusted asphalt mixture was analyzed by integrating all *** research shows that the prepared CPCMs have excellent thermal properties and durability,the phase transition temperature is 48.93℃,and the phase transition enthalpy is 106.5 J/g,which fully meets the requirements for use in *** temperature-adjusted asphalt mixture could alleviate the occurrence of extreme temperature,which was 4.9℃lower than the conventional *** pavement performance of the temperatureadjusted asphalt mixture can meet the specified standards for humid *** the factors,the recommended amount of CPCMs is 1.5%.The research results provide a basis for the promotion of temperature-adjusted asphalt pavement and effectively support the development of pavement engineering technology.

关键词： Pavement engineering Temperature-adjusted asphalt mixture Phase change materials Thermal performance

FAT10 level in human gastric cancer and its relation with mutant p53 level,lymph node metastasis and TNM staging

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World Journal of Gastroenterology 2009年第18期15卷 2228-2233页

作者： Feng Ji Xi jin Chun-Hua jiao Qin-Wei Xu Zi-Wei Wang Yue-Liang Chen Department of Digestive Diseases First Affiliated Hospital of Zhejiang University Medical SchoolHangzhou 310003 Zhejiang Province China

AIM:To investigate the role of FAT10 and mutant p53 in the pathogenesis,severity and prognosis of gastric ***:FAT10,mutant p53 mRNA and protein levels were measured by reverse transcription(RT)-PCR and immunohistochemistry in gastric cancer tissue(n = 62),tumoradjacent tissue(n = 62) and normal gastric tissue(n = 62).Relation of FAT10 and mutant p53 expression with clinicopathological features and clinical outcomes of gastric cancer patients were ***:The FAT10,mutant p53 mRNA and protein levels were signif icantly higher in gastric cancer than in its adjacent and normal *** FAT10 and mutant p53 levels in gastric cancer tissue were significantly correlated with lymph node metastasis and tumor,nodes,metastasis(TNM) ***,the high FAT10 level was associated with the overall survival rate of *** Cox-proportional hazards model analysis showed that mRNA and protein levels of FAT10 and mutant p53,lymph node metastasis,distant metastasis and TNM stage were the independent prognostic factors for gastric ***:FAT10 may be involved in gastric carcinogenesis,and is a potential marker for the prognosis of gastric cancer ***10 and mutant p53 may play a common role in the carcinogenesis of gastric cancer.

关键词： Gastric cancer FAT10 Mutant p53 Prognosis

Enrichment and analysis of circulating tumor cells by integrating multivalent membrane nano-interface and endogenous enzyme-signal amplification

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Chinese Chemical Letters 2023年第1期34卷 574-577页

作者： Mengjiao Wang Dayong Li Chengjie Duan jin jiao Youjing Gong Xiaoping Wang Zhongyun Wang Yang Xiang State Key Laboratory of Pharmaceutical Biotechnology School of Life SciencesNanjing UniversityNanjing 210023China State Key Laboratory of Natural and Biomimetic Drugs Peking UniversityBeijing 100191China Department of Neurology Tongren HospitalShanghai JiaoTong University School of MedicineShanghai 200336China Department of Anesthesiology The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China

For circulating tumor cells(CTCs)-based cancer diagnosis and monitoring,effective enrichment and specific analysis of CTCs present significant *** biomembrane interfaces can enhance the highaffinity interactions between various receptors and ligands in life activities by mediating the rearrangement and positioning of membrane-bound components through its *** by this,we have constructed a multivalent membrane nano-interface using aptamer-linked liposomes for the efficient capture of ***,the subsequent introduction of rolling circle amplification(RCA)reaction has increased the number of aptamers and extended them to the surrounding space to improve the affinity of the membrane nano-interface for *** CTCs are enriched,alkaline phosphatase overexpressed on the surface of tumor cells is used as endogenous enzyme-mediated signal amplification by catalyzing 4-nitrophenyl phosphate(p NPP)with color change,achieving the analysis of ***,the enrichment and visual analysis of human hepatocellular carcinoma(HepG2)with a detection limit of 10 cells/m L can be obtained by integrating the multivalent membrane nano-interface and endogenous enzyme signal *** detection of the target in the serum proved this method has the potential for further clinical application and provides a potential method for studying the correlation between alkaline phosphatase dimer and cancer progression.

关键词： CTCs Nano-interface Alkaline phosphatase dimer Signal amplification Liposomes

Novel 6-bp Deletion Mutation in visfatin Gene and Its Associations with Birth Weight and Bodyweight in Chinese Cattle

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Journal of Integrative Agriculture 2012年第8期11卷 1327-1332页

作者： WANG Mou ZHANG Ya YU Hui LAI Xin-sheng ZHU jin-long jiao jin-zhen LAN Xian-yong LEI Chu-zhao ZHANG Liang-zhi CHEN Hong Shaanxi Key Laboratory of Molecular Biology for Agriculture College of Animal Science and TechnologyNorthwest A&F UniversityYangling 712100P.R.China

Visfatin, like insulin, induces phosphorylation of signal transduction proteins that operatate downstream of the insulin receptor. The present study is focused on detecting deletion of visfatin gene and analyzing its effect on growth traits in six Chinese cattle breeds （Nangyang, Luxi, Qinchuan, Jiaxian Red, Grassland Red, and Chinese Holstein） using DNA sequencing, PCR-SSCP and PCR-RFLP methods. For the first time, a 6-bp deletion of visfatin was described and two alleles were revealed：W and D. The χ2-test analysis demonstrated that all breeds were in agreement with Hardy-Weinberg equilibrium （P〉0.05）. The associations of the novel 6-bp deletion of visfatin gene with growth traits of Nanyang cattle at 6-, 12-, 18-, and 24-mon-old were analyzed. Birth weight, 12- and 24-mon-old cattle with genotype WW had greater birth weight and average daily gain than genotype WD （P〈0.01 or P〈0.05）. These results suggest that the deletion may influence the birth weight and bodyweight in 12 mon-old cattle.

关键词： visfatin deletion mutation cattle