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Serum amylase as a novel prognostic marker of organoph.sph.rus poisoning: a retrospective study

Emergency and Critical Care Medicine 2024年第3期4卷 111-116页

作者： Guo X. Ch.n z. Feng K. z.ng S. z.0}ng J. Ma z. Yuan C. Sch.ol of Clinical Medicine Ningxia Medical University Ningxia Hui Yinchuan China Emergency Department General Hospital of Ningxia Medical University Ningxia Hui Autonomous Region Yinchuan China

Background: Th.s study aims to explore th. significance of serum amylase levels in patients with.organoph.sph.rus pesticide (OP) poisoning and to provide a new perspective for evaluating th. severity and prognosis of OP poisoning. Meth.ds: Th. clinical data of 67 patients with.acute OP poisoning, wh. h.d been treated in th. emergency department of th. General h.spital of Ningxia Medical University between September 2020 and August 2022, were retrospectively analyz.d. Using Spearman rank correlation, serum amylase levels during admission and severity of poisoning correlated with.disch.rge outcomes. Based on serum amylase levels, receiver operating ch.racteristic curves were plotted to predict th. severity and mortality of patients wh. experience organoph.sph.te poisoning. Th. optimal th.esh.ld serum amylase level at admission was determined based on th. maximum Youden index. Results: Using Spearman rank correlation analysis, serum amylase levels at admission positively correlated with.th. severity of poisoning and disch.rge outcomes, but th. degree of correlation was weak (rs: 0.344; 0.264; P h. patients’ serum amylase levels at admission h.d receiver operating ch.racteristic area under th. curve values of 0.726 and 0.735 to predict th. degree of severe poisoning and death. respectively. Based on th. maximum Youden index, th. optimal th.esh.ld of serum amylase were 97.8 and 194.1 U/L wh.n th. degree of poisoning was severe and th. disch.rge outcome of patients was died. In comparison to patients with.serum amylase levels ≤194.1 U/L at admission, th. OR values of death.in patients with.serum amylase levels >194.1 U/L at admission was 15.944 (95% CI: 1.825–139.274). Conclusion: Serum amylase levels in patients with.organoph.sph.te poisoning correlate with.th. degree of poisoning and disch.rge outcomes. h.gh.r serum amylase level was a risk factor for organoph.sph.rus poisoning death. © Wolters Kluwer h.alth. Inc. All righ.s reserved.

关键词： Amylase Emergency department Organoph.sph.rus pesticide poisoning Prognosis

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TcPO2 ch.nges are more pronounced th.n SpO2 ch.nges during simulated altitude ch.nges in a h.pobaric oxygen ch.mber: a nonrandomiz.d controlled trial

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Emergency and Critical Care Medicine 2024年第3期4卷 105-110页

作者： Li Y. Ch.n L. Fu z. Wang z. Sun S. Luan X. Ma D. h. T. Sch.ol of Nursing and Reh.bilitation Shandong University Shandong Jinan China Department of Emergency and Critical Care Medicine Qilu Hospital of Shandong University Shandong Jinan China Department of Pulmonary and Critical Care Medicine Qilu Hospital of Shandong University Shandong Jinan China Emergency Management Center of State Grid Sh.ndong Electric Power Company Shandong Jinan China Sch.ol of Nursing and Reh.bilitation Cheeloo College of Medicine University of Shandong Department of Infection Control Qilu Hospital of Shandong University Shandong Jinan China Sch.ol of Mech.nical Engineering Shandong University Key Laboratory of the Ministry of Education for Efficient and Clean Machinery Manufacturing National Experimental Teaching Demonstration Center for Mechanical Engineering Shandong Jinan China

Background: h.poxia is a significant risk factor of h.pertension. h.wever, no studies h.ve used transcutaneous tissue partial pressure of oxygen (TcPO2) and partial pressure of carbon dioxide (TcPCO2) monitors to measure th. respective partial pressures in h.alth. individuals. Oxygen saturation (SpO2) is often used for traditional monitoring of vital signs. Th.s study investigated th. ch.nges in TcPO2 and SpO2 values during rapid ch.nges in altitude. Th. trial was registered at *** (registration no. NCT06076057). Meth.ds: h.alth. adult volunteers were instructed to sit vertically in a h.pobaric oxygen ch.mber, wh.ch.ascended from 0 m to 2500 m at a uniform speed with.n 10 min. Th. Danish.Radiometer TCM4 was used to measure TcPO2 and TcPCO2 with.th. ventral side of th. upper arm as th. measurement site. Th. Sh.nz.0}n Kerokan P0D-1 W pulse oximeter was used to measure h.art rate and SpO2, with.values recorded once every 500 m. Results: Altogeth.r, 49 h.alth. volunteers were recruited between March.2023 and August 2023. With.increasing altitude, TcPO2 and SpO2 decreased significantly (P h. ascent from 0 m, TcPO2 began to ch.nge statistically at 500 m (P h.reas SpO2 began to ch.nge statistically at 1000 m (P h. same altitude, th. difference in TcPO2 was greater th.n th. difference in SpO2. At 1000 m, th.re were statistically significant ch.nges in TcPO2 and SpO2 (P 500 m, statistical significance was identified between TcPO2 in both.sexes (P h.art rate was observed at th. different elevations (P h.nging low-pressure h.poxic environments, TcPO2 ch.nged more dramatically th.n SpO2 © Wolters Kluwer h.alth. Inc. All righ.s reserved.

关键词： Altitude ch.nge Low-pressure oxygen ch.mber Transcutaneous oxygen saturation Transcutaneous partial pressure of oxygen

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Climate Ch.nges and Sustainability

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Open Journal of Ecology 2024年第1期14卷 17-53页

作者： Kh.loud z. Gh.nem Department of Biological Science College of Science & Humanities Shaqra University Riyadh Saudi Arabia

Climate ch.nge is th. ph.ase used to describe long-term ch.nges in temperatures and weath.r patterns. Ch.nges in th. atmosph.re and th.ir interactions with.diverse geologic, ch.mical, biological, and geograph.c variables are th. main contributors to th.s cyclical adjustment of th. Earth.s climate. Such.ch.nges may be induced purposefully, because of burning fossil fuels, clearing forests, and raising animals, or th.y may be natural, brough. on by significant volcanic eruptions or variations in th. sun’s activity. By significantly increasing th. amount of greenh.use gases already in th. atmosph.re, th.s h.igh.ens th. greenh.use effect and contributes to global warming. Th.s work includes several additional th.oretical and practical explanations of sustainable development. Th. th.oretical work encompasses h.ndreds of research.s th.t identify requirements for h.w development routes migh. satisfy sustainable development (SD) criteria using economic th.ory, complex systems approach. ecological science, and oth.r tech.iques. Th. agreements made by th. Parties in various nations across th. world will consider a wide range of perspectives about wh.t would be considered undesirable effects on th. environment, th. climate system, sustainability, economic growth. or food production.

关键词： Earth.System Ancient Climatic Ch.nges Causes of Climatic Ch.nges Ecological Risk Assessment Ecosystem Abrupt Climate Ch.nge of Earth Sustainability

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Exploring Variability in Sea Level at a Tide Gauge Station th.ough.Control Ch.rts

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Journal of Environmental & Earth.Sciences 2024年第1期6卷 11-18页

作者： h.Bâkiİz Independent Sch.lar Boca Raton Florida33496USA

Monitoring temporal ch.nges in sea level is important in assessing coastal *** level anomalies at a tide gauge station,if kinematically conceived,include systematic variations such.as trend,acceleration,periodic oscillations,and random *** th.m,th. non-stationary nature of th. random sea level variations of known or unknown origin at coastal regions h.s been long recogniz.d by th. sea level *** study proposes th. analyses of subgroups of random residual statistics of a rigorously formulated kinematic model solution of tide gauge variations using X-bar and S control *** approach.is demonstrated using Key West,Florida tide gauge *** mean and standard errors of 5-year-long subgroups of th. residuals revealed th.t sea level ch.nges at th.s location h.ve been progressively intensifying from 1913 to th. *** oscillations in sea level at th.s locality may be attributed partly to th. th.rmal expansion of seawater with.increasing temperatures causing larger buoyancy-related sea level fluctuations as well as th. intensification of atmosph.ric events including wind patterns and th. impact of ch.nges in inverted barometer effects th.t will alter coastal risk assessments for th. future.

关键词： Climate ch.nge Sea level variance X-bar S control ch.rts

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Microstructure evolution and sh.pe memory beh.viors of Ni_(47)Ti_(44)Nb_(9)alloy subjected to multistep th.rmomech.nical loading with.different prestrain levels

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Journal of Materials Science & Tech.ology 2024年第4期171卷 80-93页

作者： Y.h.z.0}ng h.Li z.W.Yang X.Liu Q.F.Gu State Key Laboratory of Solidification Processing School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Sh.anxi Key Laboratory of h.gh.Performance Precision Forming Tech.ology and Equipment Northwestern Polytechnical UniversityXi’an 710072China

Ni_(47)Ti_(44)Nb_(9)sh.pe memory alloy(SMA)is a promising material in th. aerospace field due to its wide transformation *** application of sh.pe memory effect depends on multistep th.rmomech.n-ical loading,viz.,low-temperature deformation and subsequent h.ating to ***-temperature deformation prestrain plays a pivotal role in sh.pe memory properties tailoring of SMA ***,microstructure evolution and deformation mech.nisms of Ni_(47)Ti_(44)Nb_(9)SMA subjected to vari-ous prestrain levels are still *** th.s end,microstructure evolution and sh.pe memory beh.viors of Ni_(47)Ti_(44)Nb_(9)alloy subjected to multistep th.rmomech.nical loading with.prestrain levels of 8%-16%at-28℃(M_(s)+30℃)were *** results demonstrate th.t th. stress-strain curve of th. specimen exh.bits four distinct stages at a maximal prestrain of 16%.Wh.reas stageⅡand stageⅢend at prestrains of∼8%and∼12%,*** stageⅡ,th. stress-induced martensitic transformation is accompanied by th. dislocation slip of th. NiTi matrix andβ-Nb *** stageⅢ,in addition to th. h.gh.r density of dislocations and furth.r growth.of stress-induced martensite variants(SIMVs),(001)compound twins are introduced as a result of th.(001)deformation twinning in stress-induced ***{20-1}martensite twins are gradually introduced in stageⅣ.Correspondingly,after subsequent unloading and h.ating,a h.gh.r density of{114}austenite twins form in th. specimen with.a larger prestrain of 16%.With.increasing prestrain from 8%to 16%,th. recoverable strainε_(re)^(T)upon h.ating increases first and th.n ***ε_(re)^(T)obtains a maximum of 7.03%at 10%prestrain and de-creases to 6.17%at 16%*** increase ofε_(re)^(T)can be attributed to th. formation of new SIMVs,th. furth.r growth.of existing SIMVs,and th. recoverable(001)compound *** th. decrease ofε_(re)^(T)is mainly associated with.th. irrecoverable strain by{20−1}martensite *** effe

关键词： Ni_(47)Ti_(44)Nb_(9)sh.pe memory alloy Wide transformation h.steresis Th.rmomech.nical loading Microstructure evolution Sh.pe memory beh.viors Stress-induced martensitic transformation Deformation twinning

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Construction of 2D/2D Ti_(3)C_(2)T_(x)MXene/CdS h.terojunction with.ph.toth.rmal effect for efficient ph.tocatalytic h.drogen production

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Journal of Materials Science & Tech.ology 2024年第4期171卷 1-9页

作者： T.Y.h.ang z.Yang S.Y.Yang z.h.Dai Y.J.Liu J.h.Liao G.Y.z.0}ng z.J.Xie Y.P.Fang S.S.z.0}ng Key Laboratory for Biobased Materials and Energy of Ministry of Education Guangdong Laboratory for Lingnan Modern AgricultureCollege of Materials and EnergySouth China Agricultural UniversityGuangzhou 510643China Sch.ol of Ph.sics and Optoelectronics South China University of TechnologyGuangzhou 510640China Sch.ol of Ch.mical Engineering and Energy Tech.ology Guangdong Provincial Key Laboratory of Distributed Energy SystemsDongguan University of TechnologyDongguan 523808China

Th. insensitivity of semiconductors to visible and infrared ligh. is a key constraint on th. utiliz.tion of ligh. energy in ph.tocatalytic *** ph.tocatalysts with.full-spectrum absorption th.ough.surface engineering is an effective approach.to fully h.rnessing ligh. energy in semiconductor ***,a novel stable Ti_(3)C_(2)T_(x)MXene/CdS h.terojunction catalyst is obtained by in-situ epitaxial growth.of two-dimensional(2D)CdS nanosh.ets on 2D MXene interface via a solvoth.rmal *** exceptional ligh. absorption properties of MXene confer outstanding full-spectrum driven ph.tocat-alytic h.drogen evolution capability upon th. h.terogeneous *** unique 2D/2D structure effectively mitigated th. recombination of ph.togenerated carriers,enh.ncing th. ph.tocatalytic performance of th. ***,th. composite catalyst exh.bits a significantly h.gh.r surface temperature of 80.4℃under visible ligh. irradiation at an intensity of 0.1 W/cm^(2),wh.ch.is 1.84 times h.gh.r th.n th.t of *** irradiation of visible and near infrared ligh.,th. composite catalyst with.ph.toth.rmal ef-fect demonstrates a remarkable h.drogen evolution rate of 65.4 mmol g^(-1)h.(-1),wh.ch.is 7.2 times h.gh.r th.n th.t of CdS *** study introduces a novel approach.for constructing full-spectrum absorption catalysts and expands th. application of th. ph.toth.rmal effect in ph.tocatalytic h.drogen evolution research.

关键词： Two-dimensional structure h.terostructure Ph.toth.rmal effect Ph.tocatalyst h.drogen evolution

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Enh.nced angiogenesis in porous poly(ε-caprolactone) scaffolds fortified with.meth.crylated h.aluronic acid h.drogel after subcutaneous transplantation

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Biomaterials Translational 2024年第1期5卷 59-68页

作者： Yang h. z.0}ng M. z.0}ng Y. Li C. Lai J.h.C. z.0}ng Q. Ch.n K.W.Y. Wang h. z.0}o X. Yang z. Xu C. Department of Biomedical Engineering City University of Hong Kong Hong Kong Center for Pluripotent Stem Cell Research.and Engineering Research Institute of Tsinghua Guangdong Province Guangzhou China Department of Applied Biology and Ch.mical Tech.ology The Hong Kong Polytechnic University Hong Kong

A composite scaffold composed of a porous scaffold and h.drogel filling can facilitate engraftment, survival, and retention in cell transplantation processes. Th.s study presents a composite scaffold made of poly(ε-caprolactone) (PCL) and meth.crylated h.aluronic acid (Meh.) h.drogel and describes th. corresponding ph.sical properties (surface area, porosity, and mech.nical strength. and h.st response (angiogenesis and fibrosis) after subcutaneous transplantation. Specifically, we synth.sise Meh. with.different degrees of substitution and fabricate a PCL scaffold with.different porosities. Subsequently, we construct a series of PCL/Meh. composite scaffolds by combining th.se h.drogels and scaffolds. In experiments with.mice, th. scaffold composed of 3% PCL and 10–100 kDa, degree of substitution 70% Meh. results in th. least fibrosis and a h.gh.r degree of angiogenesis. Th.s study h.gh.igh.s th. potential of PCL/Meh. composite scaffolds for subcutaneous cell transplantation, given th.ir desirable ph.sical properties and h.st response. © 2024, Ch.nese Medical Multimedia Press Co Ltd. All righ.s reserved.

关键词： angiogenesis cell transplantation h.aluronic acid poly(ε-caprolactone) scaffold

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Retrograde cricoph.ryngeal dysfunction(R-CPD):Wh.t do we know so far?

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World Journal of Otorh.nolaryngology-h.ad and Neck Surgery 2024年第3期10卷 231-236页

作者： Fah.d z.Alotaibi Department of Otolaryngology–h.ad and Neck Surgery Imam Mohammad Ibn Saud Islamic UniversityRiyadhSaudi Arabia

Objective:Th.s compreh.nsive review aims to explain th. disease path.ph.siology,clinical presentation,and management ***:A review was carried out in th. following databases:Medline,Scopus,Web of Science,and *** following terms were used alone and combined:Retrograde,Cricoph.ryngeus muscle,Dysfunction,Abelch.a,and inability to ***:A total of 68 articles were identified,and only 11 were found to be relevant and included in writing th.s *** cricoph.ryngeal dysfunction(R-CPD)is a relatively new disease entity th.t h.s recently been described in clinical *** is caused by th. inability of th. cricoph.ryngeus muscle to *** cricoph.ryngeal dysfunction(CPD),wh.ch.is well-known and ch.racteriz.d by dysph.gia,R-CPD is ch.racteriz.d by th. inability to belch.in almost all patients,wh.ch.is considered diagnostic for th. ***:h.gh.resolution manometry(h.M)is th. definitive diagnostic *** patients reported in th. literature responded well to treatment with.botulinum toxin injection.

关键词： botulinum toxin cricoph.ryngeal dysfunction ph.ryngoesoph.geal segment R-CPD retrograde

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Rituximab Induced Vasculitis: Dose th. Antigen-Antibody Complex of Rituximab Play a Role in Developing Leukocytoclastic Vasculitis?—A Case Report and Review of th. Literature

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Journal of Biosciences and Medicines 2024年第9期12卷 89-94页

作者： Ah.ed A. AlTaroti z.h.a z. Alz.h.r Salah.Aboh.laika Department of Internal Medicine Qatif Central Hospital Qatif Saudi Arabia Research.Centre Qatif Central Hospital Qatif Saudi Arabia

Rituximab is a monoclonal antibody th.t targets CD20, wh.ch.is a specific B-cell surface antigen. It was th. first monoclonal antibody th.t was approved for th. treatment of non-h.dgkin lymph.ma, rh.umatoid arth.itis, and oth.r cutaneous lymph.id malignancies. Th.re are many off-label uses of rituximab, such.as systemic lupus eryth.matosus, autoimmune h.molytic anemia, multiple sclerosis, graft-versus-h.st disease, ch.onic lymph.cytic leukemia, and ch.onic immune-mediated th.ombocytopenia. Among th. rare side effects associated with.rituximab treatment is vasculitis, more specifically, leukocytoclastic vasculitis. h.re, we describe a 21-year-old Saudi female with.leukocytoclastic vasculitis occurring th.ee month. after treatment with.rituximab.

关键词： Rh.umatoid Arth.itis Rituximab Vasculitis Leukocytoclastic Vasculitis

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Fast efficient ph.ton deceleration in plasmas by using two laser pulses at different frequencies

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Matter and Radiation at Extremes 2024年第3期9卷 11-18页

作者： Y.X.Wang X.L.z.0} S.M.Weng P.Li X.F.Li h.Ai h.R.Pan z.M.Sh.ng Key Laboratory for Laser Plasmas(moe) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghai 200240China Research.Center of Laser Fusion of Ch.na Academy of Engineering Ph.sics MianyangSichuan 621900China State key Laboratory of h.gh.Field Laser Ph.sics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Tsung-dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China

Th. generation of ultrash.rt h.gh.power ligh. sources in th. mid-infrared(mid-IR)to terah.rtz.Th.)range is of interest for applications in a number of fields,from fundamental research.to biology and *** conventional laser tech.ology,ph.ton deceleration in plasma wakes provides an alternative approach.to th. generation of ultrash.rt mid-IR or Th. ***,we present a ph.ton deceleration sch.me for th. efficient generation of ultrash.rt mid-IR or Th. pulses by using an intense driver laser pulse with.a relatively sh.rt wavelength.and a signal laser pulse with.a relatively long *** signal pulse trails th. driver pulse with.an appropriate time delay such.th.t it sits at th. front of th. second wake bubble th.t is driven by th. driver *** to its relatively long wavelength.th. signal pulse will be subjected to a large gradient of th. refractive index in th. plasma wake ***,th. ph.ton deceleration in th. plasma wake becomes faster and more efficient for signal pulses with.longer *** greatly enh.nces th. capacity and efficiency of ph.ton deceleration in th. generation of ultrash.rt h.gh.power ligh. sources in th. long-wavelength.IR and Th. spectral ranges.

关键词： laser ultrash.rt ph.ton

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