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Dimensional Analysis and Physical Similarity of Lossy Electromagnetic Systems

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Chinese Physics Letters 1993年第6期10卷 347-350页

作者： SHI Zhendong DING Chunsheng chen jiayu Department of Microwave Engineering University of Electronic Science and Technology of ChinaChengdu 610054

The dimensional analysis is applied to the model measurements of lossy electromagnetic *** physical similarity between prototype and model system is *** this theory,it is predictable that which conditions for the mode... 详细信息

关键词： system similarity satisfied

One-step synthesis of thermally stable artificial multienzyme cascade system for efficient enzymatic electrochemical detection

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Nano Research 2019年第12期12卷 3031-3036页

作者： Xiqing cheng Jinhong Zhou jiayu chen Zhaoxiong Xie Qin Kuang Lansun Zheng State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materialsand Department of ChemistryCollege of Chemistry and Chemical Engineering Xiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China

Recently,metal-organic framework(MOF)-based multienzyme systems integrating different functional natural enzymes and/or nanomaterial-basedartificial enzymes are attracting increasing attention due to their high catalytic efficiency and promising application in *** controllable integration of enzymes or nanozymes within MOFs is crucial for achieving efficient cascade catalysis and high ***,we report a facile electrochemical assisted biomimetic mineralization strategy to prepare an artificial multienzyme system for efficient electrochemicaldetection of *** using the G0x@Cu-MOF/copper foam(G0x@Cu-MOF/CF)architecture as a proof of concept,efficientenzyme immobilization and cascade catalysis were achieved by in situ encapsulation of glucose oxidase(GOx)within MOFs layer grown onthree-dimensional(3D)porous conducting CF via a facile one-step electrochemical assisted biomimetic mineralization *** to thebio-electrocatalytic cascade reaction mechanism,this well-designed GOx@Cu-MOF modified electrode exhibited superior catalytic activityand thermal stability for glucose ***,the activity of GOx@Cu-MOF/CF still remained at ca.80%after being incubated at 80℃.In sharp contrast,the activity of the unprotected electrode was reduced to the original 10%after the same *** design strategypresented here may be useful in fabricating highly stable enzyme@MOF composites applied for efficient photothermal therapy and otherplatform under high temperature.

关键词： metal-organic frameworks artificial multienzyme electrochemical assisted biomimetic mineralization glucose detection thermal stability

Occurrence and distribution of antibiotic resistance genes in the sediments of the East China Sea bays

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Journal of Environmental Sciences 2019年第7期31卷 156-167页

作者： jiayu chen Zhiguo Su Tianjiao Dai Bei Huang Qinglin Mu Yongming Zhang Donghui Wen School of Environmental and Geography Sciences Shanghai Normal University College of Environmental Sciences and Engineering Peking University Zhejiang Provincial Zhoushan Marine Ecological Environmental Monitoring Station

The coastal area of the East China Sea has experienced rapid urbanization and industrialization in China since 1980 s, resulting in severe pollution of its *** resistance genes(ARGs) are regarded as a kind of emerging pollutant with potential high risk. The sediment samples were collected from Hangzhou Bay(HB),Xiangshan Bay(XB), and Taizhou Bay(TB) to investigate the spatial occurrence and distribution of 27 ARGs and class I integron–integrase gene(intI1) in the coastal area of the East China Sea. The PCR results showed the frequent presence of 11 ARGs and intI1 in the sediments of the three bays. The qPCR results further showed that sulfonamide resistance was the most prevalent ARG type and antibiotic target replacement and protection were the most important resistance mechanisms in the sediments. Regarding the subtype of ARGs, sulI, tetW, and dfrA13 were the most abundant ARGs, in which sulI was higher in TB(based on both the absolute and relative abundances) and dfrA13 was higher in HB(based on the relative abundances). The network analysis revealed that intI1 had significant correlations with tetC, sulI, sulII, and blaPSE-1. Oil was the key connected factor, which had positive connections with sulI, sulII, and blaPSE-1. In addition, the joint effect of heavy metals and nutrients & organic pollutants might be crucial for the fate of ARGs in the coastal sediments.

关键词： Antibiotic resistance genes (ARGs) Class I integron–integrase gene(intI1) the East China Sea sediment

Solvent-dependent evolution of cyclic penta-twinned rhodium icosahedral nanocrystals and their enhanced catalytic properties

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Nano Research 2018年第2期11卷 656-664页

作者： Yanan Yang Jiawei Zhang Yajing Wei Qiaoli chen Zhenming Cao Huiqi Li jiayu chen Jueli Shi Zhaoxiong Xie Lansun Zheng State Key Laboratory for Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials Department of Chemistry College of Chemistry and Chemical Engineering Xiamen University Xiamen China

Cyclic penta-twinned noble metal nanocrystals exhibit promising properties due to their unique geometric and electronic structures. However, the controlled synthesis of cyclic penta-twinned nanostructures, especially of noble metals with a high cohesive energy （e.g., Rh）, is very difficult, and the corresponding growth mechanism is not fully understood. Herein, we report a facile one-pot hydrothermal approach for the synthesis of cyclic penta-twinned Rh icosahedral nanocrystals. It was found that apart from regulating the surface free energy by changing the concentration or category of the capping agents, the solvent might influence the adsorption ability of the surfactant on the Rh crystal surface, which results in a change in the surface free energy and thus allows the formation of Rh cyclic penta-twinned nanostructures. In addition, due to their unique electronic and geometric structures, the Rh icosahedral nanocrystals exhibit superior catalytic activity and stability for the electrooxidation of ethanol as compared to single-crystal Rh tetrahedral nanocrystals and commercial Rh black.

关键词： Rhrcrystal growth icosahedron tetrahedron electrocatalysis

Influence of earthquake input angle on seismic response of curved girder bridge

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Journal of Traffic and Transportation Engineering(English Edition) 2015年第4期2卷 233-241页

作者： Yongjun Ni jiayu chen Hualiang Teng Hui Jiang Department of Civil and Environmental Engineering University of Nevada-Las Vegas School of Civil Engineering Beijing Jiaotong University Central Research Institute of Building and Construction Co. Ltd.

The maximum seismic response of curved bridge is significantly related to the input angle of designated earthquake. Owing to structure irregularities, bridge reactions result from the interaction between the moment and torsion forces. Based on the solving of the seismic response of structure excited by a one-way earthquake input, a uniform expression of the unfavorable angle of the earthquake input was derived, and the corresponding maximum response of structure was determined. Considering the orthotropic and skewed dual- directional earthquake input manners, the most unfavorable angles for the two cases were also derived, respectively. Furthermore, a series finite element models were built to analyze the multi-component seismic responses by examining an example of curved girder bridge considering the variation of curvature radius and the bearings arrangement. The seismic responses of the case bridges, were excited by earthquakes at different input angles, and were calculated and analyzed using a response spectrum method. The input angles of earthquake excitation were progressively increased. From the analysis and comparison based on the calculation results mentioned above, the most unfavorable angle of earthquake excitation corresponding to the maximum seismic response of the curved bridge could be determined. It was shown that the most unfavorable angles of earthquake input resulted from the different response combination methods were essentially coherent.

关键词： Curved girder bridgeEarthquake inputSeismic responseUnfavorable angle

Improved in situ sequencing for high-resolution targeted spatial transcriptomic analysis in tissue sections

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Journal of Genetics and Genomics 2023年第9期50卷 652-660页

作者： Xinbin Tang jiayu chen Xinya Zhang Xuzhu Liu Zhaoxiang Xie Kaipeng Wei Jianlong Qiu Weiyan Ma chen Lin Rongqin Ke School of Medicine and School of Biomedical Sciences Huaqiao UniversityQuanzhouFujian 362021China Department of Pathology The 910 HospitalQuanzhouFujian 362000China

Spatial transcriptomics enables the study of localization-indexed gene expression activity in tissues,providing the transcriptional landscape that in turn indicates the potential regulatory networks of gene *** situ sequencing(ISS)is a targeted spatial transcriptomic technique,based on padlock probe and rolling circle amplification combined with next-generation sequencing chemistry,for highly multiplexed in situ gene expression ***,we present improved in situ sequencing(IISS)that exploits a new probing and barcoding approach,combined with advanced image analysis pipelines for high-resolution targeted spatial gene expression *** develop an improved combinatorial probe anchor ligation chemistry using a 2-base encoding strategy for barcode *** new encoding strategy results in higher signal intensity as well as improved specificity for in situ sequencing,while maintaining a streamlined analysis pipeline for targeted spatial *** show that IISS can be applied to both fresh frozen tissue and formalin-fixed paraffin-embedded tissue sections for single-cell level spatial gene expression analysis,based on which the developmental trajectory and cell-cell communication networks can also be constructed.

关键词： Spatial transcriptomics In situsequencing Single cell Geneexpression profiling Imaging

Pathogenesis of seizures and epilepsy after stroke

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Acta Epileptologica 2022年第1期5卷 16-21页

作者： jiayu chen Haijiao Ye Jie Zhang Aihong Li Yaohui Ni Department of Neurology Affiliated Hospital of Nantong UniversityNantong UniversityNantong 226001JiangsuChina

Stroke is the most frequent cause of secondary epilepsy in the *** incidence of cerebral stroke is increasing with the extension of life expectancy,and the prevalence of post-stroke epilepsy(PSE)is *** are various seizure types after stroke,and the occurrence of epilepsy is closely related to the type and location of ***,the clinical treatment of post-stroke epilepsy is difficult,which increases the risk of disability and death,and affects the prognosis and quality of life of *** seizure and epilepsy after stroke is more and more get the attention of the medical profession,has been more and more researchers have devoted to seizures after stroke and PSE clinical and basic research,and hope to get a scientific and unified guideline,to give timely and effective treatment,but the exact pathophysiologic mechanism has not yet formed a unified *** has been found that ion channels,neurotransmitters,proliferation of glial cells,genetics and other factors are involved in the occurrence and development of *** this review,we discuss the pathogenesis of early-onset epileptic seizures and late-onset epilepsy after stroke,in order to provide a basis for clinicians to understand the disease,and expect to provide ideas for future exploration.

关键词： Stroke Epilepsy Pathogenesis

The governance of imported 2019-nCov infections:What can be learned from China’s experience?

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Global Health Research and Policy 2022年第1期7卷 517-523页

作者： Hao Li Jiaxin He jiayu chen Shuning Pan Jiehan Feng Shuang Liu Global Health Institute/School of Public Health Wuhan UniversityWuhanChina School of Law Henan UniversityKaifengChina Shenzhen Health Development Research and Data Management Center ShenzhenChina Institute of International Law Wuhan UniversityWuhanChina Law School Tianjin UniversityNo.92Weijin RoadNankai DistrictTianjin 300072China

Delta and Omicron variants of 2019-nCoV are still spreading globally,and many imported infections have been identified in China as *** order to control the spread chain from imported to local,China has implemented the dynamic Covid-zero *** this article we summarized China’s governance models and practices of fighting potential imported infections in two *** targets at international travelers,which can be outlined as four lines of defense:customs epidemic prevention,quarantine upon arrival,relevant laws and regulations,and community *** other is against other vectors potentially carrying 2019-nCoV,which can be outlined by three lines of defense:customs epidemic prevention,disinfection and personal protection,and information ***,there are still some challenges that are yet to be addressed,such as illegal immigration,accidental occupational exposure to 2019-nCoV,***’s experience indicates that no country can stay safe during the global pandemic as long as there are local outbreaks in other countries,and active prevention and control measures based on science and a complete set of laws and regulations are still necessary at current ***’s more,accountable government commitment and leadership,strengthened health and social governance systems,and whole society participation are *** is suggested that the global community continue to closely cooperate together and take active rather than passive actions to block the potential imported 2019-nCoV from causing local spreading.

关键词： 2019-nCoV COVID-19 Imported infection Policy implication China

Excitatory Crossmodal Input to a Widespread Population of Primary Sensory Cortical Neurons

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Neuroscience Bulletin 2022年第10期38卷 1139-1152页

作者： Yuan-Jie Xiao Lidan Wang Yu-Zhang Liu jiayu chen Haoyu Zhang Yan Gao Hua He Zheng Zhao Zhiru Wang Institute and Key Laboratory of Brain Functional Genomics of the Chinese Ministry of Education Shanghai Key Laboratory of Brain Functional GenomicsSchool of Life SciencesEast China Normal UniversityShanghai200062China Department of Neurosurgery Third Affiliated Hospital of the Navy Military Medical UniversityShanghai200438China Department of Neuroscience University of PittsburghPittsburgh15260USA

Crossmodal information processing in sensory cortices has been reported in sparsely distributed neurons under normal conditions and can undergo experience-or activity-induced *** the potential role in brain function as indicated by previous reports,crossmodal connectivity in the sensory cortex needs to be further *** perforated whole-cell recording in anesthetized adult rats,we found that almost all neurons recorded in the primary somatosensory,auditory,and visual cortices exhibited significant membrane-potential responses to crossmodal stimulation,as recorded when brain activity states were pharmacologically down-regulated in light *** crossmodal cortical responses were excitatory and subthreshold,and further seemed to be relayed primarily by the sensory thalamus,but not the sensory cortex,of the stimulated *** experiments indicate a sensory cortical presence of widespread excitatory crossmodal inputs,which might play roles in brain functions involving crossmodal information processing or plasticity.

关键词： Crossmodal input Crossmodal response Crossmodal plasticity Sensory cortex Crossmodal task Sensory loss GABAergic transmission