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中国麻风皮肤病杂志 2024年第1期40卷 55-56页

作者：张秋鹂常建民北京医院皮肤科国家老年医学中心中国医学科学院老年医学研究院北京100730

网状血管内皮细胞瘤是一种罕见的血管肿瘤,本文报道一例网状血管内皮细胞瘤患者,背部皮肤结节1年,结合临床和组织病理学表现,诊断为网状血管内皮细胞瘤,给予手术切除。

关键词：网状血管内皮细胞瘤血管肿瘤

Chinese expert consensus on the diagnosis and treatment of balanoposthitis

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Chinese Medical Journal 2024年第13期137卷 1519-1521页

作者： Li Zhang Amer A.A.Abdulrahman Hao Guo Jia’an Zhang Xinghua Gao Weihua Pan Gang Wang Jinhua Xu Yuling Shi Liuqing Chen Hongxiang Chen Songmei Geng Yuping Ran Hongwei Wang Xiaoyong Man jianmin chang Furen Zhang Litao Zhang Guangwen Yin Jianzhong Zhang Wei Lai Zhibin Niu Hongkun Jiang Haibo Liu Yaolong Chen Jianjian Wang Department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110001China Key Laboratory of Immunodermatology Ministry of Education and NHCNational Joint Engineering Research Center for Theranostics of Immunological Skin DiseasesShenyangLiaoning 110001China Department of Dermatology Chinese Academy of Medical Science and Peking Union Medical CollegeNanjingJiangsu 210042China Department of Dermatology Second Affiliated Hospital of Naval Medical UniversityShanghai 200003China Department of Dermatology Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Dermatology Huashan HospitalFudan UniversityShanghai 200040China Department of Dermatology Shanghai Skin Disease HospitalTongji University School of MedicineShanghai 200443China Department of Dermatology Wuhan No.1 HospitalWuhanHubei 430022China Department of Dermatology Huazhong University of Science and Technology Union Shenzhen HospitalShenzhenGuangdong 518052China Department of Dermatology Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China Department of Dermatovenereology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Dermatology Huadong HospitalFudan UniversityShanghai 200040China Department of Dermatology Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310009China Department of Dermatology Beijing HospitalBeijing 100730China Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venereology Shandong First Medical University&Shandong Academy of Medical SciencesJinanShandong 250061China Department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300120China Department of Dermatology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Dermatology Peking University People’s HospitalBeijing 100044 China Department of Dermatology Third Affi

Balanoposthitis(BP),a common male genitalia inflammation,is managed by clinicians from different specialties,including urology,pediatrics,dermatology,and *** to this diverse array of clinicians involved,there exists a lack of consistent,evidence-based recommendations for *** development of the consensus engaged 19 representative hospitals and it adhered to rigorous protocols,encompassing international registration(IPGRP-2021CN003)and the application of evidence grading criteria and recommendation standards[Appendix S1,Supplementary File,http://***/CM9/C42].Over the period from December 2020 to October 2022,consensus on 12 clinical issues was reached through comprehensive evidence searches and two iterations of Delphi surveys[Supplementary File,http://***/CM9/C42].

关键词： Delphi diagnosis rigorous

Comments on“Anatomically distinct fibroblast subsets determine skin autoimmune patterns”

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Chinese Medical Journal 2022年第14期135卷 1695-1696页

作者： Yudi Chen jianmin chang Department of Dermatology Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China

Vitiligo is an autoimmune skin disorder characterized by white patches of the skin losing functional epidermal *** depigmentation of the skin impairs patients’quality of life *** than 80%of patients with vitiligo have bilateral symmetric patterns of depigmentation,which is classified as nonsegmental ***,few research revealed the cellular and molecular mechanisms that orchestrate the patterned activities of cutaneous immune cells in vitiligo *** what orchestrates the activities of cutaneous immune cells is essential for determining the therapeutic targets of the disease.

关键词： autoimmune patients Vit

肥大细胞在特应性皮炎发病中的作用及相关治疗进展

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中华临床免疫和变态反应杂志 2024年第2期18卷 174-180页

作者：陈玉迪刘琬杨敏常建民北京医院皮肤科国家老年医学中心中国医学科学院老年医学研究院北京100730

特应性皮炎(atopic dermatitis,AD)发病机制复杂,多种细胞参与其发病过程。肥大细胞主要分布于皮肤和黏膜,是多种变态反应性疾病的重要效应细胞,但肥大细胞在AD发病机制中的作用尚不完全明确。研究表明,肥大细胞主要通过“IgE-FcεRI-... 详细信息

特应性皮炎(atopic dermatitis,AD)发病机制复杂,多种细胞参与其发病过程。肥大细胞主要分布于皮肤和黏膜,是多种变态反应性疾病的重要效应细胞,但肥大细胞在AD发病机制中的作用尚不完全明确。研究表明,肥大细胞主要通过“IgE-FcεRI-组胺”途径和“MrgprB2/X2-类胰蛋白酶”途径在AD的发病中发挥作用,同时肥大细胞还释放多种2型炎症相关细胞因子进一步促进AD的免疫失衡。本文主要回顾近年来肥大细胞在AD发病机制中的研究及相关治疗进展,以期为AD的治疗与管理提供新思路。

关键词：肥大细胞特应性皮炎高亲和力IgE受体 mas相关G蛋白偶联受体

Ionic Liquid-Enhanced Assembly of Nanomaterials for Highly Stable Flexible Transparent Electrodes

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Nano-Micro Letters 2024年第7期16卷 441-455页

作者： jianmin Yang Li chang Xiqi Zhang Ziquan Cao Lei Jiang Key Laboratory of Bio-Inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China College of Chemistry and Chemical Engineering Chongqing University of TechnologyChongqing 400054People’s Republic of China Binzhou Institute of Technology Binzhou 256600People’s Republic of China Nanomics Biotechnology Co. Ltd.HangzhouPeople’s Republic of China

The controlled assembly of nanomaterials has demon-strated significant potential in advancing technological ***,achieving highly efficient and low-loss assembly technique for nanomate-rials,enabling the creation of hierarchical structures with distinctive func-tionalities,remains a formidable ***,we present a method for nanomaterial assembly enhanced by ionic liquids,which enables the fabrication of highly stable,flexible,and transparent electrodes featuring an organized layered *** utilization of hydrophobic and non-volatile ionic liquids facilitates the production of stable interfaces with water,effectively preventing the sedimentation of 1D/2D nanomaterials assembled at the ***,the interfacially assembled nanomaterial monolayer exhibits an alternate self-climbing behavior,enabling layer-by-layer transfer and the formation of a well-ordered MXene-wrapped silver nanowire network *** resulting composite film not only demonstrates exceptional photoelectric performance with a sheet resistance of 9.4Ωsq^(-1) and 93%transmittance,but also showcases remarkable environmental stability and mechanical *** noteworthy is its application in transparent electromagnetic interference shielding materials and triboelectric nanogenerator *** research introduces an innovative approach to manufacture and tailor functional devices based on ordered nanomaterials.

关键词： Ionic liquids Assembly Silver nanowires MXene nanosheets Flexible transparent electrodes

Recent landscape and trends for industry-sponsored pediatric clinical trials in China from 2013 to 2022

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Pediatric Investigation 2024年第1期8卷 12-20页

作者： chang Liu Yi Liu Ling Ou Yuenan Qi jianmin Zhang Drug Clinical Trial Institution Children’s HospitalCapital Institute of PediatricsBeijingChina

Importance:Pediatric medication is a challenging issue *** trials of medications for children and implementing measures to encourage innovation for addressing unmet medical and health needs are ***:To explore the recent landscape of pediatric clinical trials of new investigational drugs conducted by pharmaceutical enterprises in China from 2013 to 2022 to provide insight into pediatric drug development in the pharmaceutical industry and regulatory policy ***:We performed a cross-sectional observational investigation of pediatric clinical trials registered from January 1,2013,to December 31,2022,on the Registration and Information Disclosure Platform for Drug Clinical Trials,the official registration platform established in 2013 for trials of new investigational drugs initiated by biopharmaceutical *** that included pediatric participants(under 18 years old)were retrieved,and their relevant characteristics were extracted and ***:In total,895 pediatric clinical trials were collected,accounting for 5.1%of the total registered clinical trials initiated prior to January 1,*** overall average annual growth rate for the number of pediatric clinical trials was 12%(P<0.001).Phase III trials accounted for the highest proportion(49.1%,439).Of the 895 trials included,736(82.2%)were domestic trials,and 159(17.8%)were international multicenter *** terms of tested drugs,investigations of biological products accounted for the largest proportion of trials(67.4%,603).Among pediatric clinical trials,studies of vaccines accounted for the largest proportion of trials(41.0%,367),followed by trials for rare diseases(17.2%,154).Furthermore,geographical distribution analysis revealed that the largest and smallest numbers of trials were conducted in North China(35.7%,320)and Northeast China(0.8%,7),***:The growth trends for industry-sponsored clinical trials involving children illust

关键词： Geographic distribution Pediatric clinical trials Pediatric medication Rare disease

CLASSIFICATION AND COMPARISON OF WOOD DRYING MODELS

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Journal of Northeast Forestry University 1993年第2期4卷 112-117页

作者： chang jianmin Dai Fangtian Northeast Forestry University Northeast Forestry University China

The Various models established by many scholar in the near years areclassified and compared between them.

关键词： Wood drying. Model. Classify Compare.

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外阴硬化性苔藓合并汗管瘤1例

中华皮肤科杂志 2022年第9期55卷 819-820页

作者：王晶常建民北京医院皮肤科国家老年医学中心中国医学科学院老年医学研究院北京100730

患者女,50岁,因外阴白色斑块伴瘙痒2年,加重1个月于2019年7月19日来我科就诊。患者2年前阴蒂部位皮肤出现色素减退,伴剧烈瘙痒,就诊于当地医院,考虑为阴道炎,给予口服药物治疗(具体不详)2周,瘙痒稍有减轻,但时有反复,未行进一步诊治。近... 详细信息

患者女,50岁,因外阴白色斑块伴瘙痒2年,加重1个月于2019年7月19日来我科就诊。患者2年前阴蒂部位皮肤出现色素减退,伴剧烈瘙痒,就诊于当地医院,考虑为阴道炎,给予口服药物治疗(具体不详)2周,瘙痒稍有减轻,但时有反复,未行进一步诊治。近1个月来自觉瘙痒加重,色素减退面积较前明显增大。患者既往体健,月经规律,家族中无类似疾病史。

关键词：白色斑块色素减退月经规律口服药物治疗汗管瘤外阴硬化性苔藓疾病史阴道炎

Release Profile of Nitrogen During Thermal Treatment of Waste Wood Packaging Materials

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Journal of Bioresources and Bioproducts 2019年第3期4卷 32-42页

作者： Jinsheng GOU Liuming SONG Hui LIU Dandan SHEN Wanxiao HU Wenliang WANG Xueyong REN jianmin chang Beijing Forestry University Key Laboratory of Wood Material Science and ApplicationMinistry of EducationBeijing100083China

Wood packaging waste with a high recycling value is one of the main components of packaging ***,most research has been focused on natural wood,and less is known about the recycling of wood-based panel waste commonly used in *** paper examined the pyrolysis of common urea-formaldehyde(UF)resin particleboard,including the decomposition characteristics of its nitrogen-containing adhesives,the product types,and how they are *** samples and pyrolysis products were analyzed by infrared *** results showed that the UF resin was the main contributor to the release of ammonia(NH3)and hydrogen cyanide(HCN).At low temperatures,more NH3 was released than the HCN,and at high temperatures,the reverse was true.A high heating rate promoted the release of the NH_(3) and *** UF resin and wood in the particleboard interacted and caused the release of the NH3 and *** results provide a reference for further study of the thermochemical regeneration of wood-based packaging waste.

关键词： wood particleboard urea-formaldehyde(UF) release profile packaging materials thermal treatment

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成人肌纤维瘤一例

中国麻风皮肤病杂志 2023年第8期39卷 594-595页

作者：何月希常建民北京医院皮肤科国家老年医学中心中国医学科学院老年医学研究院北京协和医学院北京100730

肌纤维瘤是单发的良性间叶源性肿瘤,好发于2岁以下婴幼儿,成人少见。本文报道1例成人肌纤维瘤,表现为无痛性质硬的结节,无破溃,病理可见肿瘤团块呈“双相模式”,中央可见大量血管腔、无定型黏液样物质及圆形细胞,周边见大量旋涡状胖梭... 详细信息

肌纤维瘤是单发的良性间叶源性肿瘤,好发于2岁以下婴幼儿,成人少见。本文报道1例成人肌纤维瘤,表现为无痛性质硬的结节,无破溃,病理可见肿瘤团块呈“双相模式”,中央可见大量血管腔、无定型黏液样物质及圆形细胞,周边见大量旋涡状胖梭形细胞。免疫组化SMA(+),给予手术切除。

关键词：肌纤维瘤组织病理鉴别诊断