Comments on“Anatomically distinct fibroblast subsets determine skin autoimmune patterns”

作     者：Yudi Chen Jianmin Chang Yudi Chen;Jianmin Chang

作者机构：Department of DermatologyBeijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2022年第135卷第14期

页      面：1695-1696页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

主　　题：autoimmune patients Vit 

摘      要：Vitiligo is an autoimmune skin disorder characterized by white patches of the skin losing functional epidermal *** depigmentation of the skin impairs patients’quality of life *** than 80%of patients with vitiligo have bilateral symmetric patterns of depigmentation,which is classified as nonsegmental ***,few research revealed the cellular and molecular mechanisms that orchestrate the patterned activities of cutaneous immune cells in vitiligo *** what orchestrates the activities of cutaneous immune cells is essential for determining the therapeutic targets of the disease.