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A new active rehabilitation training mode for upper limbs based on Tai Chi Pushing Hands

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Biomimetic Intelligence & Robotics 2024年第3期4卷 82-92页

作者： Xiangpan Li Liaoyuan Li jianhai Han Bingjing Guo Ganqin Du School of Mechatronics Engineering Henan University of Science and TechnologyLuoyang 471003China Henan Provincial Key Laboratory of Robotics and Intelligent Systems Luoyang 471003China School of Automotive Engineering Hubei University of Automotive TechnologyShiyan 442002China Hubei Key Laboratory of Automotive Power Train and Electronic Control Shiyan 442002China The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003China

Robot-assisted rehabilitation is a crucial approach to restoring motor function in the ***,the current training trajectory lacks sufficient theoretical or practical support,and the monotony of single-mode training is a *** Chi Pushing Hands,a beneficial and effective daily exercise,has been shown to improve balance function,psychological state,and motor function of the upper extremities in patients recovering from *** address these issues,we propose a new active rehabilitation training that incorporates Tai Chi Pushing Hands movements and yin-yang balance *** training trajectory and direction are encoded by the velocity field and consist of two processes:yang(push)and yin(return).During yang,the limb actively pushes the robot to move,while during yin,the limb actively follows the robot’s *** provide necessary assistance,an admittance controller with self-adaptive parameters is *** addition,we introduce two indexes,the‘Intention Angle’(ϖ)and the time ratio(Γ),to evaluate motion perception *** experiment was conducted on a 4-degree-of-freedom upper limb rehabilitation robot platform,and the subjects were separated into a familiar group and an unfamiliar *** experiment results show that the training could be completed well no matter whether the subject is familiar with Tai Chi Pushing Hands or *** parameters and the movement of the robot can be adjusted based on the interactive force to adapt to the ability of the subject.

关键词： Tai Chi Push Hands Velocity field Self-adaptive admittance Upper limb rehabilitation Active training

Short-term and imminent geomagnetic anomalies of the Wenchuan M_S8.0 earthquake and exploration on earthquake forecast

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Earthquake Science 2009年第2期22卷 135-141页

作者： Wuxing Wang jianhai Ding Surong Yu Yongxian Zhang Laboratory of Computational Geodynamics Graduate University of Chinese Academy of Sciences Beijing 100049 China Institute of Earthquake Science China Earthquake Administration Beijing 100036 China China Earthquake Networks Center China Earthquake Administration Beijing 100045 China

The diurnal variation of the geomagnetic vertical component is exhibited mainly by changes of phase and amplitude before strong earthquakes. Based on data recorded by the network of geomagnetic observatories in China for many years, the anomalous features of the appearance time of the minima of diurnal variations （i.e, low-point time） of the geo- magnetic vertical components and the variation of their spatial distribution （i.e, phenomena of low-point displacement） have been studied before the Wenchuan Ms8.0 earthquake. The strong aftershocks after two months＇ quiescence of M6 aftershocks of the Ms8.0 event were forecasted based on these studies. There are good correlativities between these geomagnetic anoma- lies and occurrences of earthquakes. It has been found that most earthquakes occur near the boundary line of sudden changes of the low-point time and generally within four days before or after the 27th or 41st day counting from the day of the appearance of the anomaly. In addition, the imminent anomalies in diurnal-variation amplitudes near the epicentral areas have also been studied before the Wenchuan earthquake.

关键词： geomagnetic low-point displacement diurnal-variation amplitude Wenchuan earthquake short-term and imminent geomagnetic anomaly forecast of strong earthquakes

A comparative study between Embosphere~ and conventional transcatheter arterial chemoembolization for treatment of unresectable liver metastasis from GIST

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Chinese Journal of Cancer Research 2014年第1期26卷 124-131页

作者： Guang Cao Xu Zhu Jian Li Lin Shen Renjie yang Hui Chen Xiaodong Wang Song Gao Haifeng Xu Linzhong Zhu Peng Liu jianhai Guo Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Interventional TherapyPeking University Cancer Hospital&Institute Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Gastrointestinal OncologyPeking University Cancer Hospital&Institute

Objective：Transcatheter arterial chemoembolization （TACE） is a standard treatment for hepatocellular carcinoma （HCC） and/or some unresectable liver metastasis *** liver metastatic lesions such as metastasis from gastrointestinal stromal tumor （GIST） are an indication for transcatheter arterial embolization （TAE）.The purpose of this study was to evaluate the efficacy and safety of Embosphere（㊣）-TAE （Embo-TAE） in comparison with conventional TACE （cTACE） for the treatment of liver metastasis from ***：A total of 45 patients who underwent TACE between Aug 2008 and Feb 2013 were *** with GIST who underwent TAE with Embosphere（㊣）（n=19） were compared with controls who received cTACE （n=26）.The primary end points were treatment response and treatment-related adverse *** secondary end points were progression-free survival （PFS） and overall survival （OS）.Results：The treatment response of Embo-TAE group was significandy higher than that of the cTACE group （P＜0.001）.The PFS was significandy better in the Embosphere（㊣）-group than in the cTACE group （56.6 and 42.1 weeks,respectively; P=0.003）.However,there was no statistically significant difference in liver toxicity between the two groups （P＞0.05）.The median OS in the Embo-TAE group was longer than that in the cTACE group （74.0 weeks,95％ CI：68.2-79.8 vs.61.7 weeks,95％ CI：56.2-67.2 weeks）（unadjusted P=0.045）.The use of Embo-TAE significantly reduced the risk of death in patients with GIST with liver metastases according to the Cox proportonal hazards regression model [hazard ratio （HR）：0.149; 95％ CI：0.064-0.475].Conclusions：TAE with Embosphcre（㊣） showed better treatment response and delayed tumor progression compared with *** was no significant difference in treatment-related hepatic *** thus appears to be a feasible and promising approach in the treatment of liver metastasis from GIST.

关键词： Transcatheter arterial chemoembolization (TACE) gastrointestinal stromal tumor (GIST) embolization

Blast damage zone strength reduction method for deep cavern excavation and its application

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Frontiers of Structural and Civil Engineering 2024年第2期18卷 236-251页

作者： Tianzhi YAO Zuguo MO Li QIAN Yunpeng GAO jianhai ZHANG Xianglin XING Enlong LIU Ru ZHANG State Key Laboratory of Hydraulics and Mountain River Engineering College of Water Resources and HydropowerSichuan UniversityChengdu 610065China Power China Chengdu Engineering Corporation Limited Chengdu 610072China

The drill and blast(D&B)method is widely used to excavate underground spaces,but explosions generally cause damage to the ***,no blast simulation method can provide computational accuracy and *** this paper,a blast equivalent simulation method called the blast damage zone strength reduction(BDZSR)method is *** method first calculates the range of the blast-induced damage zone(BDZ)by formulae,then reduces the strength and deformation parameters of the rock within the BDZ ahead of excavation,and finally calculates the excavation damage zone(EDZ)for the D&B method by numerical *** method combines stress wave attenuation,rock damage criteria and stress path variation to derive the BDZ depth calculation *** formulae consider the initial geo-stress,and the reliability is verified by numerical *** calculation of BDZ depth with these formulae allows the corresponding numerical simulation to avoid the time-consuming dynamic calculation process,thus greatly enhancing the calculation *** method was applied to the excavation in Jinping Class II hydropower station to verify its *** results show that the BDZSR method can be applied to blast simulation of underground caverns and provide a new way to study blast-induced damage.

关键词： attenuation of stress wave deep-buried underground building drill and blast in situ stress

Malaria Diagnosis and Verification--China,2017–2018

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China CDC weekly 2020年第17期2卷 285-288页

作者： jianhai Yin Li Zhang Jun Feng Shuisen Zhou Zhigui Xia National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionChinese Center for Tropical Diseases ResearchWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesMinistry of Science and TechnologyKey Laboratory of Parasite and Vector BiologyMinistry of HealthShanghaiChina.

What is already known about this topic?Prompt,accurate diagnosis is an essential part of malaria elimination *** malaria diagnosis capacity will be a potential risk for malaria *** is added by this report?Health facilities at the county and prefectural levels were the most concentrated facilities for initial diagnosis of malaria(68.2%)and confirmation(76.4%).More than 65%of cases could not be diagnosed within 1 day of onset,and only 89.4%of laboratory-confirmed cases were *** are the implications for public health practice?Malaria health education should be strengthened to improve public awareness and health professionals’vigilance of malaria,thereby shortening the diagnostic *** addition,the capacity of malaria diagnosis,especially Plasmodium speciation,should be improved to ensure accurate diagnosis and appropriate treatment.

关键词： diagnosis Malaria thereby

A macro-mesoscopic constitutive model for porous and cracked rock under true triaxial conditions

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 3080-3098页

作者： Li Qian Zuguo Mo jianhai Zhang Xianglin Xing Ru Zhang Tianzhi Yao Yunpeng Gao State Key Laboratory of Hydraulics and Mountain River Engineering College of Water Resources and HydropowerSichuan UniversityChengdu610065China Power China Chengdu Engineering Corporation Limited Chengdu610072China

The complex mechanical and damage mechanisms of rocks are intricately tied to their diverse mineral compositions and the formation of pores and cracks under external *** rock tests reveal a complex interplay between the closure of porous defects and the propagation of induced cracks,presenting challenges in accurately representing their mechanical properties,especially under true triaxial stress *** paper proposes a conceptualization of rock at the mesoscopic level as a two-phase composite,consisting of a bonded medium matrix and frictional medium *** bonded medium is characterized as a mesoscopic elastic material,encompassing various minerals surrounding porous *** mechanical properties are determined using the mixed multi-inclusion *** of the bonded medium into the frictional medium occurs through crack extension,with its elastoplastic properties defined by the DruckerePrager yield criterion,accounting for hardening,softening,and *** and Eshelby’s equivalent inclusion methods are applied to the bonded and frictional media,*** macroscopic mechanical properties of the rock are derived from these mesoscopic ***,a True Triaxial Macro-Mesoscopic(TTMM)constitutive model is *** model effectively captures the competitive effect and accurately describes the stress-deformation characteristics of *** the TTMM model,the strains resulting from porous defect closure and induced crack extension are differentiated,enabling quantitative determination of the associated damage evolution.

关键词： Micromechanics Macroemesoscopic Homogenization Constitutive model Competitive effect

老年糖尿病患者踝关节骨折手术治疗的效果分析

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中国骨与关节外科 2016年第4期9卷 283-286页

作者：芦浩徐海林姜保国付中国张殿英王天兵张培训薛峰陈建海党育杨明北京大学人民医院创伤骨科北京100044

背景：近年来,手术治疗合并糖尿病的踝关节骨折病例不断增加。如何控制围术期血糖,降低术后伤口不愈合,感染以及骨折不愈合的风险,是手术治疗成功的关键。目的：研究老年糖尿病患者踝关节骨折的手术治疗效果。方法：2010年1月至2015年1... 详细信息

背景：近年来,手术治疗合并糖尿病的踝关节骨折病例不断增加。如何控制围术期血糖,降低术后伤口不愈合,感染以及骨折不愈合的风险,是手术治疗成功的关键。目的：研究老年糖尿病患者踝关节骨折的手术治疗效果。方法：2010年1月至2015年10月手术治疗老年急性闭合性踝关节骨折87例。20例合并糖尿病,男3例,女17例：年龄62-80岁,平均68.6岁。非糖尿病组患者67例,男30例,女37例：年龄60-85岁,平均66.1岁。比较两组患者术后伤口拆线时间,伤口并发症,术后感染,骨折愈合情况以及AOFAS评分。结果：85例患者获得随访。随访时间7-76个月,平均34.6个月。两组患者术后伤口拆线时间及AOFAS评分比较均无统计学差异（P〉0.05）。非糖尿病组有2例患者术后出现外踝伤口不愈合,换药治疗后伤口愈合。糖尿病组有2例患者术后内踝伤口不愈合,换药治疗后伤口愈合;2例患者术后出现外踝伤口感染,二次手术清创并取出外踝内固定物。所有患者的骨折均愈合。结论：在不伴有靶器官损害的老年糖尿病患者中,手术治疗踝关节骨折可以取得满意的疗效。在伴有靶器官损害的患者中,术后并发症的发病率较高。仔细的术前评估,良好的围手术期血糖控制,合理的分期手术,术中小心的软组织处理,坚强的骨折内固定,术后的保护性制动以及避免早期负重是取得良好治疗效果的关键。

关键词：糖尿病踝骨折

Molecular cloning and expression analysis of Crustin-like gene from Chinese shrimp Fenneropenaeus chinensis

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Acta Oceanologica Sinica 2008年第2期27卷 81-92页

作者： LIU Fengsong LI Fuhua XIANG jianhai DONG Bo LIU Yichen ZHANG Xiaojun ZHANG Liusuo College of Life Science Hebei University Baoding 071002 China Experimental Marine Biology Laboratory Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China

A new member of antimicrobial protein genes of the Crustin family was cloned from haemocytes of the Chinese shrimp Fennero- penaeus chinensis by 3 ′and 5′ RACE. The full-length cDNA of Crustin-like gene contains a 390 bp open reading frame, encoding 130 amino acids. The deduced peptide contains a putative signal peptide of 17 amino acids and mature peptide of 113 amino acids. The molecular mass of the deduced mature peptide is 12. 3 ku. It is highly cationic with a theoretical isoelectric point of 8.5. The deduced amino acids sequence of this Crustin showed high homology with those of Penaeus （ Litopenaeus ） setferus. Northern blotting showed that the cloned Crustin gene was mainly expressed in haemocytes, gill, intestine, and RNA in situ hybridization indicated that the Crustin gene was constitutively expressed exclusively in haemocytes of these tissues. Capillary elec- trophoresis RT-PCR analysis showed that Crustin was up-regulated dramatically from 12 to 48 h after a brief decrease of mRNA during first 6 h in response to microbe infection. The level of Crustin mRNA began to restore at 72 h post-challenge. This indicated that Crustin gene might play an important role when shrimps are infected by bacterial pathogen.

关键词： Crustin-like gene Fenneropenaeius chinensis molecular cloning expression analysis microbe challenge

Solution-based processing of carbon nitride composite for boosted photocatalytic activities

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Chinese Chemical Letters 2018年第3期29卷 437-440页

作者： Yile Chen Zhongshen Zhan jianhai Wang Yanfei Shen Songqin Liu Yuanjian Zhang Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research School of Chemistry and Chemical Engineering Medical School Southeast University

Graphite-phase polymeric carbon nitride （CN） was reported to be a promising material in photoelectrochemical solar energy conversion. However, its high recombination rate of photogenerated carriers limits its potential applications. In this article, a heterojunction of CN and sulfur-doped CN （CNS） was constructed through a solution-based processing way. Interestingly, it was observed that the photocatalytic hydrogen production of the as-prepared composite was 32.6 times higher than that of bulk carbon nitride and 2.3 times higher than that of the composites by conventional impregnating method. This study opens a new avenue to construct heterojunction of CN for large-scale industrial applications in environmental remediation.

关键词： Graphitic carbon nitride Heterojunction Composite Solution-based processing Photocatalytic hydrogen evolution