检索结果-南通市图书馆

Bcl-2 enhances the formation of newborn striatal long-projection neurons in adult rat brain after a transient ischemic stroke

引用

Neuroscience Bulletin 2012年第6期28卷 669-679页

作者： jian-jun guo Fang Liu Xiao Sun jun-Jie Huang Ming Xu Feng-Yan Sun Department of Neurobiology and Institute of Stem Cell Research Institutes for Biomedical ScienceShanghai Medical CollegeFudan University State Key Laboratory of Medical Neurobiology of Fudan University

Objective It has been reported that B-cell lymphoma 2 （Bcl-2） enhances neurogenesis as well as supporting axonal growth after injury. In the present study, we investigated whether Bcl-2 overexpression plays a role in the formation of newborn striatonigral projection neurons in the adult rat brain after transient middle cerebral artery occlusion （MCAO）. Methods We infused human Bcl-2-expressing plasmid （pBcl-2） into the lateral ventricle immediately after 30 min of MCAO, injected 5＇-bromodeoxyuridine （BrdU） intraperitoneally to label proliferative cells, and microinjected fluorogold （FG） into the substantia nigra at 11 weeks of reperfusion followed by multiple immunostaining of striatonigral projection neurons at 12 weeks. Results We found that pBcl-2 treatment significantly increased the number of newborn neurons （BrdU＋-NeuN＋） in the striatum ipsilateral to the MCAO. We further detected newborn striatonigral projection neurons （BrdU＋-FG＋-NeuN＋） in the ipsilateral striatum at 12 weeks. More interestingly, the number of newborn striatonigral projection neurons （BrdU＋-FG＋） was significantly increased by pBcl-2 treatment compared to that by pEGFP, a control plasmid. Conclusion Taken together, we found that Bcl-2 overexpression in the brain enhanced the generation of newborn striatonigral projection neurons. This provides a potential strategy for promoting the reestablishment of neural networks and brain repair after ischemic injury.

关键词： cerebral ischemia Bcl-2 striatonigral projection neuron neurogenesis brain repair

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adsorption and retention of fracturing fluid and its impact on gas transport in tight sandstone with different clay minerals

引用

Petroleum Science 2025年第1期22卷 370-383页

作者： Yi-jun Wang Li-jun You jian Yang Yi-Li Kang Ming-jun Chen Jia-Jia Bai jian Tian State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum University Engineering Technology Research Institute of Southwest Oil & Gas Field Company PetroChina School of Petroleum Engineering Changzhou University State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing University

To elucidate the adsorption characteristics and retention mechanisms of fracturing fluids in diverse clay minerals, we conducted on-line nuclear magnetic resonance(NMR) and atomic force microscopy(AFM)experiments. The depth and extent of solid phase damage are determined by the ratio between the size of fine fractions in fracturing fluid residue and the pore-throat size in experiments. Poor physical properties(K 0.5 m D) combined with a scattered distribution of retained fracturing fluid is associated with high gas phase recovery permeability, whereas a continuous sheet-like distribution results in low recovery permeability. The expansive surface area and presence of filamentous illite minerals facilitate the multiple winding and adsorption of fracturing fluids, demonstrating strong hydrogen-bonding, multi-layering and multiple adsorption properties. The geological characteristics of the main gas formations exhibit significant variation, and the severity of damage caused by fracturing fluids occurs in diverse sequences. To address this issue, a differentiated strategy for optimizing fracturing fluids has been proposed.

关键词： Clay minerals Formation damage Fracturing fluid retention distribution Adsorption morphology

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Combustion aerosols and suspended dust with controlled processes in Lhasa:Elemental analysis and size distribution characteristics

引用

Journal of Environmental Sciences 2025年第2期148卷 591-601页

作者： Jinglin Li Zhuoga Deqing Jie Liang Tao guo jian Yao Wei Liu Shanghai Institute of Applied Physics Chinese Academy of ScienceShanghai 201800China University of Chinese Academy of Science Beijing 100049China Meteorological Bureau of Tibet Autonomous Region Lhasa 850000China

To explore air contamination resulting from special biomass combustion and suspended dust in Lhasa,the present study focused on the size distribution and chemical characteristics of particulate matter(PM)emission resulting from 7 types of non-fossil pollution *** investigated the concentration and size distribution of trace elements from 7 pollution sources collected in *** Lhasa’s atmospheric particulate matter data,enrichment factors(EFs)have been calculated to examine the potential impact of those pollution sources on the atmosphere quality of *** highest mass concentration of total elements of biomass combustion appeared at PM_(0.4),and the second highest concentration existed in the size fraction 0.4-1μm;the higher proportion(12%)of toxicmetals was produced by biomass *** elemental composition of suspended dust and atmospheric particulate matter was close(except for As and Cd);the highest concentration of elements was all noted in PM_(2.5-10)(PM3-10).Potassium was found to be one of the main biomass *** proportion of Cu in suspended dust is significantly lower than that of atmospheric particulate matter(0.53%and 3.75%),which indicates that there are other anthropogenic *** EFs analysis showed that the Cr,Cu,Zn,and Pb produced by biomass combustion were highly enriched(EFs>100)in all particle *** EFs of most trace elements increased with decreasing particle size,indicating the greater influence of humanfactors on smaller particles.

关键词： Size distribution Trace elements Particulate matter Enrichment factors Lhasa

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gradient age-precipitation behavior induced by gradient nano-grain in Mg-Gd-Ag-Zr alloy

引用

Journal of Iron and Steel Research International 2025年第1期32卷 19-24页

作者： Bang-jun Li Jia-peng Sun Jing Han guo-song Wu College of Materials Science and Engineering Hohai UniversityNanjing 210024JiangsuChina School of Mechanical and Electrical Engineering China University of Mining and TechnologyXuzhou 221116JiangsuChina

Gradient nano-grained structure is frequently engineered into metallic materials,including Mg alloys,to achieve superior combination of strength and ***,the influence of this microstructural feature on aging precipitation behavior remains inadequately *** this study,the age-precipitation behavior of a gradient nano-grained Mg-Gd-Ag-Zr alloy prepared via ultrasonic severe surface rolling was *** result indicates that the aging precipitation behavior exhibits a depth-dependent variation within this *** the nano-grained surface layer,hierarchicalβnano-precipitates are predominant,while at greater depths,the precipitates consist ofβnanoparticles located at grain boundaries,along with intragranularβ′andγ″*** formation ofβnano-precipitates deviates from the conventional precipitation behavior observed in Mg-Gd-Ag alloys,and is attributed to the high density of defects induced by the surface nano-grained *** finding advances our understanding of the precipitation behavior in the alloys with heterogeneous microstructure.

关键词： Mg alloy Gradient Precipitation Aging behavior Microstructure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

冷激蛋白的研究进展

引用

生物化学与生物物理进展 2002年第5期29卷 691-695页

作者：郭建军龚兴国浙江大学生物技术系杭州310027

冷激蛋白 (CSPs)广泛存在于革兰氏阳性菌和阴性菌中 ,它是细胞在应对冷刺激时所产生的一系列 7ku左右的蛋白质 ,结构上富含芳香族氨基酸 ,起着重要的分子伴侣作用 ,能够增强细胞抵御冷激环境胁迫的能力 .以大肠杆菌、枯草杆菌、嗜热链... 详细信息

冷激蛋白 (CSPs)广泛存在于革兰氏阳性菌和阴性菌中 ,它是细胞在应对冷刺激时所产生的一系列 7ku左右的蛋白质 ,结构上富含芳香族氨基酸 ,起着重要的分子伴侣作用 ,能够增强细胞抵御冷激环境胁迫的能力 .以大肠杆菌、枯草杆菌、嗜热链球菌、沙门氏杆菌等为例 ,介绍各种冷激蛋白在产生、结构、调控等方面的异同 ,以及它在生产。

关键词：冷激蛋白研究进展分子伴侣细胞生长

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Carboniferous-Early Permian heterogeneous distribution of porous carbonate reservoirs in the Central Uplift of the South Yellow Sea Basin and its hydrocarbon potential analysis

引用

China Geology 2025年第1期8卷 58-76页

作者： Shu-yu Wu jun Liu jian-wen Chen Qi-liang Sun Yin-guo Zhang Jie Liang Yong-cai Feng School of Engineering China University of GeoscienceWuhan 430074China Yantai Center of Coastal Zone Geological Survey China Geological SurveyMinistry of Natural ResourcesYantai 264001China Key Laboratory of Submarine Geosicences Ministry of Natural ResourcesHangzhou 310012China Chinese Academy of Geological Sciences China Geological SurveyMinistry of Natural ResourcesBeijing 100037China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266061China The Key Laboratory of Gas Hydrate Ministry of Natural ResourcesQingdao Institute of Marine GeologyChina Geological SurveyMinistry of Natural ResourcesQingdao 266071China College of Marine Science and Technology China University of GeoscienceWuhan 430074China

Mesozoic-Palaeozoic marine carbonate rocks are crucial hydrocarbon reservoirs in the Central Uplift area of the South Yellow Sea Basin(SYSB).Due to the scarcity of boreholes and the significant heterogeneity of carbonate reservoirs,the distribution of porous carbonate reservoirs and their related key controlling factors remain *** this study,factors affecting the distribution of porous Carboniferous-Early Permian carbonate reservoirs in the SYSB were investigated through seismic inversion and isotope *** log-seismic characteristics of porous carbonate reservoirs,sensitive lithology parameters,and physical property parameters were extracted and *** pre-stack simultaneous inversion technique was applied to predict the lithology and physical properties of porous carbonate ***,the sedimentary of carbonate was analyzed using isotopes of carbon,oxygen,and *** results show that porous carbonate reservoirs are mainly developed in the open platform sediments with porosities of 3%-5%and are mainly distributed in the paleo-highland(Huanglong Formation and Chuanshan Formation)and the slope of paleo-highland(Hezhou Formation).The porous carbonate reservoirs of the Qixia Formation are only locally *** addition,the negativeδ13C excursions indicate a warm and humid tropical climate with three sea-level fluctuations in the study area from the Carboniferous to Early *** favorable conditions for developing porous carbonate rocks include the sedimentary environment and diagenetic *** primary pore tends to form in high-energy environments of the paleo-highland,and the secondary pore is increased by dissolution during the syngenetic or quasi-syngenetic *** to the hydrocarbon potential analysis,the Late Ordovician Wufeng Formation and Lower Silurian Gaojiabian Formation are the source rocks in the high-maturity-over-maturity stage,the Carboniferous-Lower Permian carbonate is the good reservoirs,and th

关键词： Sedimentary Heterogeneous porous carbonate reservoirs C-H-Sr isotope analysis Carboniferous-Early Permian Chuanshan Formation Huanglong Formation Pre-stack simultaneous inversion technique Oil-gas exploration engineering Hydrocarbon accumulation Hydrocarbon potential Central Uplift of the South Yellow Sea Basin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insights into microscopic oil occurrence characteristics in shales from the Paleogene Funing Formation in Subei Basin, China

引用

Petroleum Science 2025年第1期22卷 55-75页

作者： jun-Jie Wang Peng-Fei Zhang Shuang-Fang Lu Zi-Zhi Lin Wen-Biao Li jun-jian Zhang Wei-Zheng Gao Neng-Wu Zhou guo-Hui Chen Ya-Jie Yin Han Wu Sanya Offshore Oil & Gas Research Institute of Northeast Petroleum University College of Earth Science and Engineering Shandong University of Science and Technology Key Laboratory of Continental Shale Hydrocarbon Accumulation and Efficient Development Ministry of Education Northeast Petroleum University School of Geoscience China University of Petroleum (East China)

The microscopic occurrence characteristics primarily constrain the enrichment and mobility of shale *** study collected the lacustrine shales from the Palaeogene Funing Formation in the Gaoyou Sag, Subei Basin. Conventional and multistage Rock-Eval, scanning electron microscopy, and nuclear magnetic resonance(NMR) T1-T2were performed to analyze the contents and occurrence characteristics of shale oil. Low-temperature nitrogen adsorption-desorption(LTNA/D) experiments were conducted on the shales before and after extraction. The relationships between shale oil occurrence with organic matter and pore structures were then discussed. Predominantly, the shale oil in the Funing Formation is found within fractures, with secondary occurrences in interparticle pores linked to brittle minerals and sizeable intraparticle pores associated with clay minerals. The selected shales can be categorized into two types based on the nitrogen isotherms. Type A shales are characterized by high contents of felsic and calcareous minerals but low clay minerals, with larger TOC and shale oil values. Conversely, Type B shales are marked by abundant clay minerals but diminished TOC and shale oil contents. The lower BET specific surface area(SSA), larger average pore diameter, and simpler pore surfaces and pore structures lead to the Type A shales being more conducive to shale oil enrichment and mobility. Shale oil content is predominantly governed by the abundance of organic matter, while an overabundance of organic matter typically equates to a reduced ratio of free oil and diminished fluidity. The BET SSA, volumes of pores less than 25 and 100 nm at extracted state all correlate negatively with total and adsorbed oil contents but display no correlation with free oil, while they have positive relationships with capillary-bound ***, pore water is mainly saturated in micropores(<25 nm) and minipores(25-100 nm), as well as adsorbed oil, while free oil, i.e., bound and movable

关键词： Occurrence characteristic Shale oil content Pore structure Low-temperature nitrogen adsorption-desorption Gaoyou Sag

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Polypropylene-based blend with enhanced breakdown strength under gamma-ray irradiation for cable insulation

引用

Nuclear Science and Techniques 2025年第1期36卷 35-48页

作者： Bai-Xin Liu Yu Gao Jing Li Chen-Yi guo Bo-Sen Si jun-guo Gao Yu Chen Bo-Xue Du School of Electrical and Information Engineering Tianjin UniversityTianjin 300072China Key Laboratory of Engineering Dielectrics and Its Application Ministry of EducationHarbin University of Science and TechnologyHarbin 150080China State Key Laboratory of Electrical Insulation and Power Equipment Xi’an Jiaotong UniversityXi’an 710049China

This study focuses on the electrical properties and microstructure of polypropylene(PP)-based blends used for cable insulation in nuclear power plants(NPPs).The PP-based blend,comprising isotactic PP and propylene-based elastomer(PBE)at concentrations ranging from 0 to 50 wt%,underwent a melt blending process and subsequent cobalt-60 gamma-ray irradiation with doses ranging from 0 to 250 *** conductivity,trap distribution,and alternating(AC)breakdown strength were chosen to assess the insulation *** results indicate that the addition of PBE significantly improves the electrical properties of PP under *** PP,the electrical conductivity increased with irradiation,whereas the trap depth and breakdown strength decreased ***,for the blend,these changes initially exhibit opposite *** the irradiation was increased to 250 kGy,the AC breakdown strength of the blend improved by more than 21%compared to that of *** physical and chemical structures of the samples were investigated to explore the improvement *** results offer insights into the design of new cable-insulation materials suitable for NPPs.

关键词： Nuclear power plant Cable insulation Polypropylene Electrical properties Gamma-ray irradiation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Travelling characteristics of road vehicles on single-level rail-cum-road bridge under the dynamic and aerodynamic impact of travelling trains

引用

Earthquake Engineering and Engineering Vibration 2025年第1期24卷 235-256页

作者： He Jiajun Lu jun guo Wei Dong Lianjie Bai Xue Li Yongle Southwest Municipal Design&Research Institute of China Chengdu 610299China Southwest Jiaotong University Chengdu 610031China

Aerodynamic and dynamic interference from trains is a key issue of concern for the safety of road vehicles travelling on single-level rail-cum road *** on the wind-road vehicle-train-bridge(WRTB)coupled vibration system developed herein,this study examines the dynamic characteristics when road vehicles meet trains in this *** influence of load combination,vehicle type and vehicle location is analyzed.A method to obtain the aerodynamic load of road vehicles encountering the train at an arbitrary wind speed is *** results show that due to the windproof facilities and the large line distance between the railway and highway,the aerodynamic and dynamic influence of trains on road vehicles is slight,and the vibration of road vehicles depends on the road *** the road vehicles discussed,the bus is the easiest to rollover,and the truck-trailer is the easiest to *** with the aerodynamic impact of trains,the crosswind has a more significant influence on road *** first peak/valley value of aerodynamic loads determines the maximum dynamic response,and the quick method is optimized based on this *** cases show that the optimized method can produce conservative results and can be used for relevant research or engineering applications.

关键词： single-level rail-cum-road bridge vehicle-bridge coupled vibration dynamic characteristic aerodynamic impact road vehicle

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Achievable Rate Analysis and Optimization of Double-RIS Assisted Spatially Correlated MIMO with Statistical CSI

引用

China Communications 2025年第1期22卷 139-157页

作者： Xu Kaizhe guo Jiajia Zhang jun Jin Shi Ma Shaodan Department of Communications and Networking Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China State Key Laboratory of Internet of Things for Smart City University of MacaoMacao SARChina jiangsu Key Laboratory of Wireless Communications Nanjing University of Posts and TelecommunicationsNanjing 210003China National Mobile Communications Research Laboratory Southeast UniversityNanjing 210096China State Key Laboratory of Internet of Things for Smart City and the Department of Electrical and Computer Engineering University of MacaoMacao SARChina

Reconfigurable intelligent surface(RIS)is a novel meta-material which can form a smart radio environment by dynamically altering reflection directions of the impinging electromagnetic *** the prior literature,the inter-RIS links which also contribute to the performance of the whole system are usually neglected when multiple RISs are *** this paper we investigate a general double-RIS assisted multiple-input multiple-output(MIMO)wireless communication system under spatially correlated non line-of-sight propagation channels,where the cooperation of the double RISs is also *** design objective is to maximize the achievable ergodic rate based on full statistical channel state information(CSI).Specifically,we firstly present a closedform asymptotic expression for the achievable ergodic rate by utilizing replica method from statistical *** a full statistical CSI-enabled optimal design is proposed which avoids high pilot training overhead compared to instantaneous CSI-enabled *** further reduce the signal processing overhead and lower the complexity for practical realization,a common-phase scheme is proposed to design the double *** results show that the derived asymptotic ergodic rate is quite accurate even for small-sized antenna *** the proposed optimization algorithm can achieve substantial gain at the expense of a low overhead and ***,the cooperative double-RIS assisted MIMO framework is proven to achieve superior ergodic rate performance and high communication reliability under harsh propagation environment.

关键词： common reflection pattern double RISs large system analysis MIMO replica method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：