检索结果-南通市图书馆

Inhibitory effects of dobutamine on human gastric adenocarcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第45期20卷 17092-17099页

作者： Hui-Xia Zheng Li-Na Wu Hong Xiao Qian Du jian-fang liang Department of Pathology The First Hospital Shanxi Medical University

AIM: To explore the inhibitory effects of dobutamine on gastric adenocarcinoma cells.

关键词： Dobutamine Gastric adenocarcinoma cells Yes-associated protein Hippo pathway Human gastric adenocarcinoma cell line SGC-7901 Therapy

O_(2) adsorption on Fe_(3)O_(4) (110) surface and effect of gangue element Al doping: combined study of binding experiment and ab initio molecular dynamics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第4期31卷 810-827页

作者： Zheng-jian Liu Hui-qing jiang Yao-zu Wang jian-liang Zhang Hong-mei Qiao An-yang Zheng fang-yu Guo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China School of Intelligence Science and Technology University of Science and Technology BeijingBeijing 100083China Beijing Shougang Co. Ltd.Qian'an 064404HebeiChina Department of Physics National University of Defense TechnologyChangsha 410128HunanChina

At high temperature,the chemical reaction mechanism at the interface of magnetite and the influence mechanism of gangue element Al on the oxidation performance of magnetite are not *** addition,due to the limitation of existing experimental equipment,it is difficult to clarify the interface reaction mechanism in the oxidation process and the influence mechanism of Al on the surface oxidation reaction of Fe_(3)O_(4) at an atomic scale at high *** surface oxidation reaction mechanism of magnetite and the influence mechanism of Al on the oxidation of magnetite were studied by experiments and AIMD(ab initio molecular dynamics).The experimental results show that the existence of Al_(2)O_(3) will reduce the initial oxidation temperature and comprehensive oxidation performance of *** AIMD results show that aluminum can accelerate the interface reaction rate of Fe_(3)O_(4) in the high-temperature oxidation atmosphere,but the strong Al-O binding ability is not conducive to the transfer of O atoms in the oxidation process.

关键词： Ironmaking Magnetite oxidation Interface reaction Adsorption-Gangue aluminum AIMD

Sufficient Conditions for Amalgamated 3-Manifolds to be ∂-Irreducible

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,Series B 2024年第2期45卷 161-172页

作者： Bing fang Fengchun LEI liang liang School of Mathematical Sciences Dalian University of TechnologyDalian 116024LiaoningChina School of Mathematics Liaoning Normal UniversityDalian 116029LiaoningChina

In this paper,the authors give some sufficient conditions for an amalgamated 3-manifold along a compact connected surface F with boundary to be ∂-irreducible in terms of distances between some kinds of vertex subsets ... 详细信息

关键词： ∂-Irreducibility Irreducibility Amalgamated 3-manifold Curve complex Arc complex

在线全文

学校读者我要写书评

暂无评论

人群行走荷载作用下的人致结构振动

华南理工大学学报（自然科学版） 2010年第4期38卷 125-130页

作者：李昊简方梁同济大学桥梁工程系上海200092

以生物力学和交通领域相关研究成果为基础,提出了一种精细化的随机人群荷载作用下的人致结构振动分析方法.首先以生物力学试验数据为基础,拟合了人步行速度与步频之间的关系式;然后借助交通领域的人流集度与人流速度关系模型,结合目前... 详细信息

以生物力学和交通领域相关研究成果为基础,提出了一种精细化的随机人群荷载作用下的人致结构振动分析方法.首先以生物力学试验数据为基础,拟合了人步行速度与步频之间的关系式;然后借助交通领域的人流集度与人流速度关系模型,结合目前结构领域关于单人荷载模型的研究成果,建立了精细化的随机人群荷载模型,推导了该人群荷载模型下的结构动力平衡方程,并采用自编程序对该方程进行求解,得出了结构的人致响应;最后通过ISO2031标准对文中建立的荷载模型下结构的人致振动舒适性进行评价,并与BS5400荷载模型进行了比较.结果表明,文中所建立的荷载模型较好地考虑了人群荷载对结构的作用,避免了目前人群荷载作用下人致振动分析参数取值的盲目性.

关键词：人致振动人群荷载模型步频人流集度人流速度

Processing of a low-costγ-γ'NiPtAl coating with improved oxidation resistance

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第6期43卷 2832-2841页

作者： Yan jiang liang-liang Wei jian He Hong-Bo Guo School of Materials Science and Engineering Beihang UniversityBeijing 100191China Key Laboratory of High-Temperature Structural Materials and Protective Coatings Ministry of Industry and Information TechnologyBeihang UniversityBeijing 100191China

A novelγ-γ'(Ni solid solution—Ni_(3)Al)NiPtAl coating was produced on advanced single-crystal(SC)superalloy N5 by electroplating of a thin Pt coating with~3μm in thickness followed by heat treatment at 1000℃in *** comparison,a traditionalγ-γ'NiPtAl coating was also produced by electroplating of a thick Pt coating with~6μm in thickness followed by heat treatment at 1100℃in *** novel coating has a mass gain of~0.5 mg·cm^(-2)after 100 h 1-h cyclic oxidation at 1150℃,showing better oxidation resistance than the traditional *** oxide scale mostly consisting ofα-Al_(2)O_(3)grew on the novel coating because the element Cr from the SC alloy substrate contributes to the formation ofα-Al_(2)O_(3).Pt content in the novel coating has significant effect on the oxidation *** optimized Pt content in the coating is about 16 at%,which is helpful to reduce the diffusion of harmful elements from the substrate into the coating but also to reduce the cost of the coating.

关键词： γ-γ'NiPtAl coating Platinum Oxidation Al_(2)O_(3) Superalloy

Securing offshore resources development: A mathematical investigation into gas leakage in long-distance flexible pipes

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第4期21卷 2734-2744页

作者： Xiang-An Lu liang-liang jiang jian-Sheng Zhang Min-Gui Wang Guangling College of Yangzhou University Department of Chemical and Petroleum Engineering University of Calgary Department of Energy and Power Engineering Tsinghua University

Gas flexible pipes are critical multi-layered equipment for offshore oil and gas development. Under high pressure conditions, small molecular components of natural gas dissolve into the polymer inner liner of the flexible pipes and further diffuse into the annular space, incurring annular pressure build-up and/or production of acidic environment, which poses serious challenges to the structure and integrity of the flexible pipes. Gas permeation in pipes is a complex phenomenon governed by various factors such as internal pressure and temperature, annular structure, external temperature. In a long-distance gas flexible pipe, moreover, gas permeation exhibits non-uniform features, and the gas permeated into the annular space flows along the metal gap. To assess the complex gas transport behavior in long-distance gas flexible pipes, a mathematical model is established in this paper considering the multiphase flow phenomena inside the flexible pipes, the diffusion of gas in the inner liner, and the gas seepage in the annular space under varying permeable properties of the annulus. In addition, the effect of a variable temperature is accounted. A numerical calculation method is accordingly constructed to solve the coupling mathematical equations. The annular permeability was shown to significantly influence the distribution of annular pressure. As permeability increases, the annular pressure tends to become more uniform, and the annular pressure at the wellhead rises more rapidly. After annular pressure relief followed by shut-in, the pressure increase follows a convex function. By simulating the pressure recovery pattern after pressure relief and comparing it with test results, we deduce that the annular permeability lies between 123 and 512 m D. The results help shed light upon assessing the annular pressure in long distance gas flexible pipes and thus ensure the security of gas transport in the emerging development of offshore resources.

关键词： Offshore resources development Transport security Long-distance flexible pipes Gas leakage Heat and mass transfer model Finite difference calculation

Uniqueness on Difference Operators of Meromorphic Functions of Infinite Order

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第2期40卷 511-527页

作者： Hui LI Ming liang fang Xiao YAO School of Science China University of Mining and TechnologyBeijing 100083P.R.China Institute of Mathematics Academy of Mathematics and System SciencesChinese Academy of SciencesBeijing 100190P.R.China School of Sciences Hangzhou Dianzi UniversityHangzhou 310012P.R.China School of Mathematical sciences and LPMC Nankai UniversityTianjin 300071P.R.China

We investigate the uniqueness problems of meromorphic functions and their difference operators by using a new *** is proved that if a non-constant meromorphic function f shares a non-zero constant and ∞ counting multiplicities with its difference operators Δcf(z) and Δ_(c)^(2)f(z), thenΔcf(z)≡Δ_(c)^(2)f(z).In particular,we give a difference analogue of a result of *** method has two distinct features:(ⅰ) It converts the relations between functions into the corresponding *** makes it possible to deal with the uniqueness problem by linear algebra and combinatorics.(ⅱ) It circumvents the obstacle of the difference logarithmic derivative lemma for meromorphic functions of infinite order,since this method does not depend on the growth of the ***,the idea in this paper can also be applied to the case for several variables.

关键词： Uniqueness meromorphic functions difference operators infinite order

Pd-catalyzed asymmetric carbonyl alkynylation:Synthesis of axial chiral ynones

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第6期35卷 293-297页

作者： Long Jin jian Han Dongmei fang Min Wang jian Liao Natural Products Research Center Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041China College of Chemical Engineering Sichuan UniversityChengdu 610065China University of Chinese Academy of Sciences Beijing 100049China

Ynones are important skeletons in bioactive molecules and valuable building blocks for organic synthesis,thus great efforts have been devoted to their ***,introducing prochiral substrates to construct ynones bearing a chiral framework is unrealized to ***,we reported the first example of Pd/SOP-catalyzed asymmetric carbonylative alkynylation via a non-classical carbonylative Sonogashiratype approach(acyl-Pd(Ⅱ)species generated from nucleophiles).By using cyclic diaryliodonium salts as prochiral substrates,various axial chiral ynones with good functional group tolerance(39 examples),satisfied yields(71%-96%)and excellent enantioselectivities(generally 94%-99%ee)were *** of bioactive compounds,scale-up experiment and useful transformations were also conducted to demonstrate the utility of this process.

关键词： Pd-catalyzed Axial chiral ynones Cyclic diaryliodonium High-valent palladium catalyzed Asymmetric carbonyl alkynylation

Evolutionary mechanisms and practical significance of reproductive success and clonal diversity in unisexual vertebrate polyploids

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第3期67卷 449-459页

作者： Meng Lu Li Zhou jian-fang Gui State Key Laboratory of Freshwater Ecology and Biotechnology Hubei Hongshan Laboratorythe Innovation Academy of Seed DesignInstitute of HydrobiologyChinese Academy of SciencesWuhan 430072China University of Chinese Academy of Sciences Beijing 100049China

Unisexual reproduction is generally relevant to polyploidy, and unisexual vertebrates are often considered an evolutionary “dead end” due to the accumulation of deleterious mutations and absence of genetic diversity. However, some unisexual polyploids have developed strategies to avoid genomic decay, and thus provide ideal models to unveil unexplored evolutionary mechanisms, from the reproductive success to clonal diversity creation. This article reviews the evolutionary mechanisms for overcoming meiotic barrier and generating genetic diversity in unisexual vertebrates, and summarizes recent research advancements in the polyploid Carassius complex. Gynogenetic gibel carp(Carassius gibelio) is a unique amphitriploid that has undergone a recurrent autotriploidy and has overcome the bottleneck of triploid sterility via gynogenesis. Recently, an efficient strategy in which ploidy changes, including from amphitriploid to amphitetraploid, then from amphitetraploid to novel amphitriploid, drive unisexual-sexual-unisexual reproduction transition and clonal diversity has been *** on this new discovery, multigenomic reconstruction biotechnology has been used to breed a novel strain with superior growth and stronger disease resistance. Moreover, a unique reproduction mode that combines both abilities of ameiotic oogenesis and sperm-egg fusion,termed as ameio-fusiongensis, has been discovered, and it provides an efficient approach to synthesize sterile allopolyploids. In order to avoid ecological risks upon escape and protect the sustainable property rights of the aquaculture seed industry, a controllable fertility biotechnology approach for precise breeding is being developed by integrating sterile allopolyploid synthesis and gene-editing *** review provides novel insights into the origin and evolution of unisexual vertebrates and into the attempts being made to exploit new breeding biotechnologies in aquaculture.

关键词： unisexual vertebrates polyploidy reproduction transition clonal diversity precise breeding genomic reconstruction controllable fertility