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钠冷快堆钠池火事故数值模拟

原子能科学技术 2005年第5期39卷 442-446页

作者：张斌朱继洲西安交通大学能源与动力工程学院核能与热能工程系陕西西安710049

为了估计和预测钠火事故的后果,构建了以“有火焰薄层”为理论基础的燃烧模型和热传输模型,给出了程序计算结果与试验值的比较。比较结果证实,该计算结果可信、模型合理。程序可用来分析和预测钠池火事故。

关键词：钠冷快堆钠池火火焰薄层

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双质量弹簧基准问题自抗扰控制研究

控制理论与应用 2020年第4期37卷 933-940页

作者：李健张彬文谭文华北电力大学控制与计算机工程学院北京102206

本文研究了自抗扰控制(ADRC)方法在双质量弹簧基准问题的应用.传统的自抗扰控制方法倾向于使用高增益控制来抑制扰动和模型不确定性,但是对于双质量弹簧基准问题,高增益在评分中受到较大惩罚,而且对于模型参数变化没有足够的鲁棒性.为... 详细信息

本文研究了自抗扰控制(ADRC)方法在双质量弹簧基准问题的应用.传统的自抗扰控制方法倾向于使用高增益控制来抑制扰动和模型不确定性,但是对于双质量弹簧基准问题,高增益在评分中受到较大惩罚,而且对于模型参数变化没有足够的鲁棒性.为解决这一问题,本文对ADRC设计提出了两种改进方案.首先,为了减小控制信号的幅度,将扩张状态观测器(ESO)的一个极点配置在原点.其次,采用阻尼比来调整带宽.结果表明,所提出的ADRC设计可以很好地解决双质量弹簧基准系统的控制问题.

关键词：自抗扰控制双质量弹簧基准问题鲁棒控制带宽

^3H—3—叠氮基—N—正癸烷基水杨酰胺的合成

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原子能科学技术 2000年第2期34卷 132-135页

作者：吕斌武德柱陈世智徐建兴中国科学院生物物理研究所北京100101 中国原子能科学研究院同位素研究所北京102413 中国医学科学院药物研究所北京100050

以 3 硝基水杨酸和正癸烷为原料 ,合成了研究线粒体呼吸链酶系中各泛醌结合蛋白的分子探针 ,即氚标记的 3 叠氮基 N 正癸烷基水杨酰胺 ,为进一步研究泛醌结合蛋白提供了有效工具。3 H 3 叠氮基 N 正癸烷基水杨酰胺的放射性比活度和放... 详细信息

以 3 硝基水杨酸和正癸烷为原料 ,合成了研究线粒体呼吸链酶系中各泛醌结合蛋白的分子探针 ,即氚标记的 3 叠氮基 N 正癸烷基水杨酰胺 ,为进一步研究泛醌结合蛋白提供了有效工具。3 H 3 叠氮基 N 正癸烷基水杨酰胺的放射性比活度和放射化学纯度分别为 2 5 9TBq/mol和 98%

关键词：合成氚标记 3-叠氮基-N-正癸烷基水杨酰胺

Effects of antiepileptic drugs on bone mineral density and bone metabolism in children: a meta-analysis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第7期16卷 611-621页

作者： Ying ZHANG Yu-xin ZHENG Jun-ming zhu jian-min ZHANG Zhe ZHENG Neuroscience Care Unit the Second Affiliated Hospital School of Medicine Zhejiang University Department of Neurosurgery the Second Affiliated Hospital School of Medicine Zhejiang University

Objective： The aim of our meta-analysis was to assess the effects of antiepileptic drugs on bone mineral density and bone metabolism in epileptic children. Methods： Searches of Pub Med and Web of Science were undertaken to identify studies evaluating the association between antiepileptic drugs and bone mineral density and bone metabolism. Results： A total of 22 studies with 1492 subjects were included in our research. We identified：（1） a reduction in bone mineral density at lumbar spine（standardized mean difference（SMD）=-0.30, 95% confidence interval（CI） [-0.61,-0.05]）, trochanter（mean difference（MD）=-0.07, 95% CI [-0.10,-0.05]）, femoral neck（MD=-0.05, 95% CI [-0.09,-0.02]）, and total body bone mineral density（MD=-0.33, 95% CI [-0.51,-0.15]）;（2） a reduction in 25-hydroxyvitamin D（MD=-3.37, 95% CI [-5.94,-0.80]） and an increase in serum alkaline phosphatase（SMD=0.71, 95% CI [0.38, 1.05]）;（3） no significant changes in serum parathyroid hormone, calcium, or phosphorus. Conclusions： Our meta-analysis suggests that treatment with antiepileptic drugs may be associated with decreased bone mineral density in epileptic children.

关键词： Antiepileptic drugs Bone mineral density Bone metabolism Children Meta-analysis

Replication and Pathology of Duck Influenza Virus Subtype H9N2 in Chukar

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Biomedical and Environmental Sciences 2018年第4期31卷 306-310页

作者： zhu Yin Chuan ZHANG bin SUN Zeng Hu WANG Xi Jing FAN Xiao Hui GAO Ling Xi LIANG Ying CHEN Xiao Yan ZHANG Zeng Feng Department of Microbiology Guangxi Medical University

To investigate the susceptibility of Chukars to duck avian influenza virus H9N2 and explore their role in interspecies transmission of influenza *** were inoculated with duck avian influenza viruses H9N2.

关键词： In ST Replication and Pathology of Duck Influenza Virus Subtype H9N2 in Chukar

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基于流体逼近的路段交通流动态加载研究

交通运输系统工程与信息 2015年第5期15卷 195-201页

作者：纪翔峰张健冉斌东南大学城市智能交通江苏省重点实验室南京210096 现代城市交通技术江苏高校协同创新中心南京210096

路段交通流动态加载是动态交通网络分配模型中的重要组成部分,在路段交通流动态加载中,离散形式或者连续形式的点排队模型被广泛使用.本文在以往研究的基础上,提出基于流体逼近的连续型点排队模型,克服了原有点排队模型中排队负值的情况... 详细信息

路段交通流动态加载是动态交通网络分配模型中的重要组成部分,在路段交通流动态加载中,离散形式或者连续形式的点排队模型被广泛使用.本文在以往研究的基础上,提出基于流体逼近的连续型点排队模型,克服了原有点排队模型中排队负值的情况.通过分析可以发现,原有点排队模型实质上属于具有单一服务台和无限容量的排队模型,基于流体逼近的思想重新定义了原有点排队模型.其中3个主要部分是流量守恒模型,车辆流出模型和时间相关的服务台模型,这3个模型全部都是连续的.由于连续点排队对计算需求较高,本文将连续的排队模型离散化,模拟了3种不同场景下车辆驶出、路段排队情况.本文模型克服了原有点排队中的负排队现象,并且排队过程满足先进先出的原则,模型具有良好的模拟效果.

关键词：交通工程连续点排队模型排队系统流体逼近离散化非负排队先进先出

Dopamine receptor D2 polymorphism is associated with alleviation of obesity after 8-year follow-up: a retrospective cohort study in obese Chinese children and adolescents

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第10期19卷 807-814页

作者： jian-fang zhu Lian-hui CHEN Ke YUAN Li LIANG Chun-lin WANG Department of Pediatrics the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China The Second Affiliated Hospital of Fujian Medical University Quanzhou 362000China

Objective： The aim of this study was to explore the association of dopamine receptor D2 （DRD2） polymorphism and alleviation of obesity in children and adolescents after 8-year follow-up. Methods： This retrospective cohort study included obese children and adolescents with a follow-up period of 8 years. Baseline clinical character- istics and DRD2 polymorphisms （including rs1076562, rs2075654, and rs4586205） were extracted from medical records. A follow-up visit was performed in May 2017 to collect related data including height, weight, diet compliance, and exercise compliance. Results： One hundred and nine obese children and adolescents were included in the current study. Among three DRD2 single nucleotide polymorphisms, only rs2075654 had a statistically significant association with alleviation of obesity, as the alleviation rate for minor allele carders （68.6% for TC＋TT） was higher compared to the major allele homozygote （43.3% for CC）. After adjusting for all related factors, the hazard ratio of rs2075654 minor allele carders for the alleviation of obesity was 3.34 （95% confidence interval （CI）： 1.30-8.58）. Conclusions： The rs2075654 ~olvmomhism of DRD2 is related to Ionq-term obesity alleviation in obese Chinese children and adolescents.

关键词： Obesity Follow-up study Dopamine receptor D2 Children Adolescent

Effect of telehealth interventions on major cardiovascular outcomes： a metaanalysis of randomized controlled trials

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Journal of Geriatric Cardiology 2017年第8期14卷 501-508页

作者： Xiang GU Ye zhu Yi ZHANG Lei SUN Zheng-Yu BAO jian-Hua SHEN Fu-Kun CHEN Hong-Xiao LI Shu-Hang MIAO Jing-Wu WANG Qing-Qing SHI Clinical Medical College Yangzhou University Yangzhou Jiangsu China Department of Cardiology Subei People's Hospital Yangzhou Jiangsu China XiangYa School of Medicine Central South University Changsha Hunan China

Background Telehealth interventions （THI） were associated with lower levels of cardiovascular risk factors in adults, whereas the effect of THI on cardiovascular disease （CVD） still remains controversial. A meta-analysis was conducted to summarize the evidence from randomized controlled trials （RCT） which investigated potential impact of THI on the incidence of CVD in patients with or without prior CVD. Methods PubMed, EmBase, and the Cochrane Library were searched to identify RCTs to fit our analysis through December 2016. Relative risk （RR） with its 95% confidence interval （CI） was used to measure the effect of THI using a random-effect model. Sensitivity analysis, subgroup analysis, heterogeneity tests, and tests for publication bias were also conducted. Results Eight RCTs were included and with a total of 1635 individuals. The summarized results indicated that participants who received THI showed a significant reduction of the CVD incidence as compared with usual care （RR： 0.59; 95% CI： 0.47-0.74; P 〈 0.001）. Furthermore, the effect of THI was greater in patients with history ofCVD （RR： 0.55; 95% CI： 0.44-0.70; P 〈 0.001） than in patients without history ofCVD （RR： 0.99; 95% CI： 0.51-1.94; P = 0.977）. Sensitivity analysis suggested that the intervention effect persisted and the conclusion was not changed. Subgroup analysis indi- cated mean age, study quality might play an important role on the risk of CVD. Conclusions The findings of this study indicated THI could reduce the recurrence of CVD. Further large-scale trials are needed to verify the effect of THI on CVD in healthy individuals.

关键词： Cardiovascular disease Meta-analysis Telehealth interventions

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基于长周期光纤光栅的动态增益平坦滤波器

光电子．激光 2006年第3期17卷 274-279页

作者：李彬魏淮简水生北京交通大学光波技术研究所北京100044

分析了长周期光纤光栅（LPG）的啁啾特性和切趾特性，给出了基于LPG的增益平坦滤波器可调的理论依据。阐述了LPG的传感特性和金属外包层对其的影响，为动态增益平坦滤波器结构的原理提供理论支持。介绍了这种动态增益平坦滤波器的制作... 详细信息

分析了长周期光纤光栅（LPG）的啁啾特性和切趾特性，给出了基于LPG的增益平坦滤波器可调的理论依据。阐述了LPG的传感特性和金属外包层对其的影响，为动态增益平坦滤波器结构的原理提供理论支持。介绍了这种动态增益平坦滤波器的制作原理、制作过程和可调过程。这种滤波器结构简单、插损小、易于控制、可调范围宽、响应速度快以及重复性好。实验中的增益平坦滤波器在20～120℃内波长线性可调8nm；损耗峰值在20～60℃内变化小，而在60～100℃内变化大；带宽在20～60℃内变化较小，而在60～120℃内变化较大；可根据不同需要在不同的温度范围内调节滤波器的损耗峰值和带宽，实现增益平坦滤波器的动态可调。

关键词：长周期光纤光栅(LPG) 厚度渐变外包层啁啾特性增益平坦滤波器动态可调