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The Impact of Cigarette Smoking on Metabolic Syndrome

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Biomedical and Environmental Sciences 2013年第12期26卷 947-952页

作者： jia wei ping Department of Endocrinology and Metabolism Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai Clinical Center for Diabetes Shanghai Diabetes Institute Shanghai Key Laboratory of Diabetes Mellitus Shanghai Key Clinical Center for Metabolic Disease

Metabolic syndrome （MetS） is a constellation of interconnected cardiometabolic disorders, including obesity, hyperglycemia, dyslipidemia, and elevated blood pressure. MetS is a precursor to type 2 diabetes mellitus （T2DM） and cardiovascular disease （CVD）; it increases the risk of T2DM by 3-4 times[11 and the risk of CVD by 1.4-fold[21, and is more prevalent in obese individuals. As the obesity rates increase, the prevalence of MetS in the population is increased. In 2006, the global prevalence of MetS in adults was estimated to be 20%-25%TM, and in China, in 2007-2008, using the criteria of the Chinese Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults （JCDCG）, it reached 21.9% among the adult population aged 〉20 vears old[4].

关键词： The Impact of Cigarette Smoking on Metabolic Syndrome

Chinese clinical guideline for continuous glucose monitoring （2012）

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Chinese Medical Journal 2012年第23期125卷 4167-4174页

作者：无 jia wei-ping Chinese Diabetes Society Department of Endocrinology and Metabolism Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China

Glucose monitoring is an important component in diabetes treatment and management. The results of blood glucose monitoring are useful for determining the degree of glucose metabolic disturbance, evaluating therapeutic outcomes, and guiding adjustments of treatment regimens.1 Self-monitoring of blood glucose （SMBG） still remains the most common form of in-home blood glucose monitoring with the glycosylated hemoglobin （HbAlc） as the ＂gold standard＂ for understanding the patients＇ average glucose over the last 3 months. However, both HbA1 c and SMBG have certain limitations： HbAlc represents the average blood glucose level over the previous 2-3 months;

关键词： guideline continuous glucose monitoring clinical application

Biomarkers for diabetes prediction, diagnosis and personalized therapy

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Chinese Medical Journal 2012年第23期125卷 4163-4166页

作者： CHEN Hai-bing jia wei-ping Department of Endocrinology and Metabolism Shanghai JiaoTong University Affiliated Sixth People's HospitalShanghai 200233China

Diabetes mellitus （DM） is one of the most common ＇metabolic disorders in the world~ in which more than90% are grouped to type 2 DM （T2DM）.1 T2DM is characterized by decreased insulin sensitivity and impaired insulin secretion2 leading to hyperglycemia, and the serum glucose has been used as a golden standard for diabetes diagnosis. However, T2DM is a kind of disease involving defects of multiple organs, which cannot be distinguished through the measurement of the serum-glucose level. In addition, T2DM is a multiple-stage disease, which usually covers several decades from impaired plasma glucose to various complications. The serum-glucose level only reflects the consequence of multiole physiological disorders in the Riven stare.

关键词： biomarkers diabetes," prediction," personalized therapy

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冬播甘蓝型油菜生育期进程及生理生化特性

西南农业学报 2024年第7期37卷 1459-1470页

作者：王小霞刘自刚田海燕魏家萍崔俊美武泽峰董小云郑国强王莹巩永杰杨馥睿翟利佳甘肃农业大学农学院/省部共建干旱生境作物学国家重点实验室兰州730070

[目的]解决强冬性冬油菜/春油菜间杂交种生产花期不遇问题,为我国强冬性冬油菜和春油菜间杂种优势的利用提供依据。[方法]以强冬性甘蓝型冬油菜(NTS211、NTS304)和春油菜(C05、C19)为试验材料,10/11(月/日,下同)秋播甘蓝型强冬性冬油菜... 详细信息

[目的]解决强冬性冬油菜/春油菜间杂交种生产花期不遇问题,为我国强冬性冬油菜和春油菜间杂种优势的利用提供依据。[方法]以强冬性甘蓝型冬油菜(NTS211、NTS304)和春油菜(C05、C19)为试验材料,10/11(月/日,下同)秋播甘蓝型强冬性冬油菜和春油菜;12/10、12/30、1/19、2/8、2/28冬播强冬性冬油菜和春油菜,记录生育期、出苗率和结实性能,并分析各生育期叶片生理生化特性。[结果]10/11秋播甘蓝型油菜越冬前出苗,强冬性冬油菜可以安全越冬,春性油菜越冬率为0;甘蓝型油菜在12/10后播种种子在越冬期不萌发,翌年早春3/21-4/6温度回暖后,种子陆续出苗,出苗率21.0%~72.3%。冬播冬油菜花期在6/21-7/5到7/3-7/20;冬播(12/10-翌年2/8)春油菜的花期在5/10-5/12到5/25-5/30;秋播冬油菜花期在5/5-5/6到5/30;秋播冬油菜和冬播(12/10-翌年2/8)春油菜花期相遇,1/19冬播春油菜和秋播冬油菜花期叠合时间最长(18 d)。随着冬播时间推迟,冬播冬油菜花期进程延迟,生育期延长,冬播春油菜花期进程提早,生育期缩短;冬播冬油菜的结实性能呈下降趋势,冬播春油菜的千粒重呈上升趋势;冬播冬油菜和春油菜在苗期赤霉素含量呈上升趋势,在蕾薹期呈下降趋势,花期和角层期呈先上升后下降趋势;冬播冬油菜苗期的生长素含量显著高于春油菜;蕾薹期的过氧化物酶活性显著高于其余各生育期;冬油菜和春油菜的丙二醛含量在苗期最低,可溶性蛋白含量在花期最高。[结论]强冬性冬油菜秋播及春油菜冬播调解花期相遇可行,1/19冬播春油菜和秋播冬油菜花期叠合时间最长(18 d),冬播通过影响甘蓝型油菜叶片的抗氧化酶、丙二醛、渗透调节物质与内源激素,最终影响生长发育和结实性能。

关键词：冬播甘蓝型油菜生育期花期调节生理特性

Privacy-Preserving Consensus-Based Distributed Economic Dispatch of Smart Grids via State Decomposition

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1250-1261页

作者： wei Chen Guo-ping Liu The authors are with the Center for Control Science and Technology Southern University of Science and TechnologyShenzhen 518055China

This paper studies the privacy-preserving distributed economic dispatch(DED)problem of smart *** autonomous consensus-based algorithm is developed via local data exchange with neighboring nodes,which covers both the islanded mode and the grid-connected mode of smart *** prevent power-sensitive information from being disclosed,a privacy-preserving mechanism is integrated into the proposed DED algorithm by randomly decomposing the state into two parts,where only partial data is *** objective is to develop a privacy-preserving DED algorithm to achieve optimal power dispatch with the lowest generation cost under physical constraints while preventing sensitive information from being *** this end,a comprehensive analysis framework is established to ensure that the proposed algorithm can converge to the optimal solution of the concerned optimization problem by means of the consensus theory and the eigenvalue perturbation *** particular,the proposed autonomous algorithm can achieve a smooth transition between the islanded mode and the grid-connected ***,rigorous analysis is given to show privacy-preserving performance against internal and external ***,case studies illustrate the feasibility and validity of the developed algorithm.

关键词： preserving autonomous mode

Enhance the Performance of Directional Feature-based Palmprint Recognition by Directional Response Stability Measurement

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Machine Intelligence Research 2024年第3期21卷 597-614页

作者： Haitao Wang wei jia School of Computer Science and Information Engineering Hefei University of TechnologyHefei230009China

Palmprint recognition is an emerging biometrics technology that has attracted increasing attention in recent years. Many palmprint recognition methods have been proposed, including traditional methods and deep learning-based methods. Among the traditional methods, the methods based on directional features are mainstream because they have high recognition rates and are robust to illumination changes and small noises. However, to date, in these methods, the stability of the palmprint directional response has not been deeply studied. In this paper, we analyse the problem of directional response instability in palmprint recognition methods based on directional feature. We then propose a novel palmprint directional response stability measurement (DRSM) to judge the stability of the directional feature of each pixel. After filtering the palmprint image with the filter bank, we design DRSM according to the relationship between the maximum response value and other response values for each pixel. Using DRSM, we can judge those pixels with unstable directional response and use a specially designed encoding mode related to a specific method. We insert the DRSM mechanism into seven classical methods based on directional feature, and conduct many experiments on six public palmprint databases. The experimental results show that the DRSM mechanism can effectively improve the performance of these methods. In the field of palmprint recognition, this work is the first in-depth study on the stability of the palmprint directional response, so this paper has strong reference value for research on palmprint recognition methods based on directional features.

关键词： Biometrics palmprint recognition directional response stability directional coding-based methods directional feature

Role of Fibroblast Growth Factor 19 in Maintaining Nutrient Homeostasis and Disease

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Biomedical and Environmental Sciences 2014年第5期27卷 319-324页

作者： ZHANG Jing LI Hua Ting FANG Qi Chen jia wei ping Department of Endocrinology and Metabolism Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai Diabetes Institute Shanghai Key Laboratory of Diabetes Mellitus Shanghai Clinical Center for Diabetes Department of Medicine Shanghai Jiao Tong University School of Medicine

Fibroblast growth factor 19 （FGF19） is a kind of gut-derived postprandial hormone. As an atypical member of the FGF family, FGF19 functions as an endocrine hormone except regulating cell growth and differentiation. FGF19 plays a key role in coordination of liver bile acid biosynthesis and gallbladder motility, and acts as a regulator of metabolic homeostasis, including strengthening insulin sensitivity, decreasing triglyceride concentration and reducing body weight.

关键词： FGFs acid FGFR Role of Fibroblast Growth Factor 19 in Maintaining Nutrient Homeostasis and Disease

Perenniality:From model plants to applications in agriculture

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Molecular Plant 2024年第1期17卷 141-157页

作者： Bo Zhao jia-wei Wang National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant Sciences(CEMPS)Institute of Plant Physiology and Ecology(SIPPE)Chinese Academy of Sciences(CAS)Shanghai 200032China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China Key Laboratory of Plant Carbon Capture CASShanghai 200032China New Cornerstone Science Laboratory Shanghai 200032China

To compensate for their sessile nature,plants have evolved sophisticated mechanisms enabling them to adapt to ever-changing *** such prominent feature is the evolution of diverse life history strategies,particularly such that annuals reproduce once followed by seasonal death,while perennials live longer by cycling growth *** intrinsic phenology is primarily genetic and can be altered by environmental *** evolutionary transitions between annual and perennial life history strategies are common,perennials account for most species in nature because they survive well under year-round *** proportion,however,is reversed in ***,perennial crops promise to likewise protect and enhance the resilience of agricultural ecosystems in response to climate *** significant endeavors that have been made to generate perennial crops,progress is slow because of barriers in studying perennials,and many developed species await further *** findings in model species have illustrated that simply rewiring existing genetic networks can lead to lifestyle *** implies that engineering plant life history strategy can be achieved by manipulating only a few key *** this review,we summarize our current understanding of genetic basis of perenniality and discuss major questions and challenges that remain to be addressed.

关键词： perenniality developmental plasticity flowering time poplar Arabis alpina perennial crops life history strategy

Serum vaspin level in relation to postprandial plasma glucose concentration in subjects with diabetes

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Chinese Medical Journal 2009年第21期122卷 2530-2533页

作者： YE Yin HOU Xu-hong PAN Xiao-ping LU Jun-xi jia wei-ping Department of Endocrinology and Metabolism Shanghai Clinical Center for Diabetes Shanghai jiao Tong University Affiliated Sixth People's Hospital Shanghai Diabetes Institute Shanghai Key Laboratory of Diabetes Mellitus Shanghai 200233 China

Background Vaspin is a newly-identified adipocytokine related to obesity and insulin sensitivity. However, its pathophysiologic role in humans remains largely unknown. The aim of our study was to investigate the relationship between serum vaspin level and glucose metabolism or obesity in Chinese adults. Methods A total of 123 subjects, including 84 subjects with normal glucose tolerance （NGT） and 39 subjects with diabetes, were enrolled in this study. Anthropometric parameters, abdominal fat areas, plasma glucose concentration, serum insulin, lipids, and vaspin level were measured in each participant. Results Serum vaspin concentration was significantly higher in diabetic patients than that in NGT subjects （592 （438-695） pg/ml vs 380 （294-517） pg/ml, P=0.020） in women. In all participants, age, fasting plasma glucose concentration （FPG）, 2-hour post-load plasma glucose （PG2h）, hemoglobin Alc （HbAlc） and high-density lipoprotein cholesterol （HDL-c） significantly increased from the lower tertile to the higher tertile of vaspin. Univariate linear regression analyses revealed that vaspin level was only positively correlated with age （β=0.340, P=0.002） in NGT subjects. And vaspin was positively associated with FPG （β=0.365, P=0.023）, PG2h （β=0.526, P=0.001）, HbAlc （β=0.388, P=0.016）, and HDL-c （β=0.353, P=0.027）, while negatively with homeostasis model assessment of beta cell function （HOMA-β）（β=-0.361, P=-0.024） in diabetic patients. In stepwise multivariate regression analyses, age was independently associated with circulating vaspin in NGT subjects, whereas PG2h was an independent predictor of vaspin in diabetic patients. In addition, there was no significant difference of serum vaspin level between men and women. And no significant correlations between vaspin and body fat indexes were detected. Conclusions Serum vaspin level is higher in diabetic patients than that in NGT subjects in women. Age predicts serum vaspin level in NGT subjects, while PG2h is independently

关键词： vaspin protein, human blood glucose diabetes mellitus obesity