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Tumour response following preoperative chemotherapy is affected by body mass index in patients with colorectal liver metastases

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 331-342页

作者： Hua-Chuan Song Hang-Cheng zhou Ping Gu Bing Bao Quan Sun Tian-Ming Mei Wei Cui Kang Yao Huan-Zhang Yao Shen-Yu Zhang Yong-Shuai wang Rui-Peng Song ji-zhou wang Department of General Surgery Provincial Hospital Affiliated to Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Pathology The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Gastrointestinal Surgery Tongcheng People’s HospitalTongcheng 231400Anhui ProvinceChina Department of Gastrointestinal Surgery Suzhou Hospital Affiliated to Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina Department of General Surgery Xuancheng People’s HospitalXuancheng 242000Anhui ProvinceChina

BACKGROUND Colorectal cancer is the third most prevalent malignancy globally and ranks second in cancer-related mortality,with the liver being the primary organ of *** chemotherapy is widely recommended for initially or potentially resectable colorectal liver metastases(CRLMs).Tumour pathological response serves as the most important and intuitive indicator for assessing the efficacy of ***,the postoperative pathological results reveal that a considerable number of patients exhibit a poor response to preoperative *** mass index(BMI)is one of the factors affecting the tumori-genesis and progression of colorectal cancer as well as prognosis after various antitumour *** studies have indicated that overweight and obese patients with metastatic colorectal cancer experience worse prognoses than those with normal weight,particularly when receiving first-line chemotherapy regimens in combination with *** To explore the predictive value of BMI regarding the pathologic response following preoperative chemotherapy for *** A retrospective analysis was performed in 126 consecutive patients with CRLM who underwent hepatectomy following preoperative chemotherapy at four different hospitals from October 2019 to July *** and multivariate logistic regression models were applied to analyse potential predictors of tumour pathological *** Kaplan-Meier method with log rank test was used to compare progression-free survival(PFS)between patients with high and low ***<24.0 kg/m^(2) was defined as low BMI,and tumour regression grade 1-2 was defined as complete tumour *** Low BMI was observed in 74(58.7%)patients and complete tumour response was found in 27(21.4%)*** rate of complete tumour response was significantly higher in patients with low BMI(29.7%vs 9.6%,P=0.007).Multivariate analysis revealed that low BMI[odds ratio(OR)=4.56,95%confidence interval(CI):1

关键词： Colorectal liver metastases Body mass index Tumour regression grade Preoperative chemotherapy Hepatectomy

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Water Striders:The Biomechanics of Water Locomotion and Functional Morphology of the Hydrophobic Surface(Insecta:Hemiptera-Heteroptera)

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Journal of Bionic Engineering 2008年第2期5卷 121-126页

作者： P. J. Perez Goodwynj jin-tong wang zhou-ji wang Ai-hong ji Zhen-dong Dai K. Fujisaki Institute for Bio-lnspired Structure and Surface Engineering （IBSS） Nanjing University of Aeronautics andAstronautics Nanjing 210019 P. R. China Laboratory oflnsect Ecology Graduate School of.4griculture Kyoto University Kyoto 606-8502 Japan

Water striders are insects living on the water surface, over which they can move very quickly and rarely get wetted. We measured the force of free walking in water striders, using a hair attached to their backs and a 3D strain gauge. The error was calculated by comparing force and data derived from geometry and was estimated as 13%. Females on average were stronger （1.32 mN） than males （0.87 mN）, however, the ratio of force to weight was not significantly different. Compared with other lighter species, Aquarius paludum seems stronger, but the ratio of force to weight is actually lower. A. paludum applies about 0.3 ***^-1 to 0.4 *** 1 with its mid-legs, thus avoiding penetrating the surface tension layer while propelling itself rapidly over the water surface. We also investigated the external morphology with SEM. The body is covered by effectively two layers of macro-and micro-hairs, which renders them hydrophobic. The setae are long （40 μm-60μm） and stiff, being responsible for waterproofing, and the microtrichia are much smaller （〈10μm）, slender, and flexible, holding a bubble over the body when submerged.

关键词： force surface tension aquatic insect morphology microtrichia setae

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Decolorization of azo dyes with high salt concentration by salt-tolerant mixed cultures under anaerobic conditions

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Journal of Environmental Sciences 2005年第6期17卷 984-988页

作者： GUO jian-bo zhou ji-ti wang Dong wang jing YU Hui SONG Zhi-yong School of Environmental and Biological Science and Technology Dalian University of Technology Dalian 116023 China

Because the lack of detailed study of biological decolorization in high salt dye wastewater, it is still difficult to evaluate the biological treatment on high-salinity dye wastewater. The experiments were carried out to study the salt-tolerant bacteria, which is useful in the treatment of high-salinity colored wastewater. Simulated wastewater containing 5-150 g/L salt （NaCI） and 50-2000 mg/L Reactive Brilliant Red K-2BP was treated with three salt-tolerant mixed cultures （CAS, TAS, DSAS）, which were under a gradually acclimated procedure. With the increase of concentrations of salt and dye, the decolorization became low. The abilities of decolorization of dyes wastewater by three mixed cultures （CAS, TAS, DSAS） were studied, CAS and DSAS mixed cultures showed more active for the treatment of high-salinity colored wastewater than TAS mixed cultures. The results suggested that there might be a simple process for the high salt wastewater treatment, which could be incorporated into conventional activated sludge plants.

关键词： anaerobic decolorization hyper-salinity salt-tolerant mixed cultures

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Predicting the International Roughness Index of JPCP and CRCP Rigid Pavement:A Random Forest(RF)Model Hybridized with Modified Beetle Antennae Search(MBAS)for Higher Accuracy

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1557-1582页

作者： zhou ji Mengmeng zhou Qiang wang jiandong Huang College of Civil and Environmental Engineering Hunan University of Science and EngineeringYongzhou425006China School of Mines China University of Mining and TechnologyXuzhou221116China School of Civil Engineering Guangzhou UniversityGuangzhou510006China

To improve the prediction accuracy of the International Roughness Index(IRI)of Jointed PlainConcrete Pavements(JPCP)and Continuously Reinforced Concrete Pavements(CRCP),a machine learning approach is developed in this study for the modelling,combining an improved Beetle Antennae Search(MBAS)algorithm and Random Forest(RF)*** 10-fold cross-validation was applied to verify the reliability and accuracy of the model proposed in this *** importance scores of all input variables on the IRI of JPCP and CRCP were analysed as *** results by the comparative analysis showed the prediction accuracy of the IRI of the newly developed MBAS and RF hybrid machine learning model(RF-MBAS)in this study is higher,indicated by the RMSE and R values of 0.2732 and 0.9476 for the JPCP as well as the RMSE and R values of 0.1863 and 0.9182 for the *** accuracy of this obtained result far exceeds that of the IRI prediction model used in the traditional Mechanistic-Empirical Pavement Design Guide(MEPDG),indicating the great potential of this developed *** importance analysis showed that the IRI of JPCP and CRCP was proportional to the corresponding input variables in this study,including the total joint faulting cumulated per KM(TFAULT),percent subgrade material passing the 0.075-mm Sieve(P_(200))and pavement surface area with flexible and rigid patching(all Severities)(PATCH)which scored higher.

关键词： Cement pavement JPCP CRCP RF-MBAS IRI

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Bunch-length measurement at a bunch-by-bunch rate based on time–frequency-domain joint analysis techniques and its application

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Nuclear Science and Techniques 2024年第4期35卷 165-175页

作者： Hong-Shuang wang Xing Yang Yong-Bin Leng Yi-Mei zhou ji-Gang wang Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230026China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China

This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage *** technique uses the time–frequency-domain joint analysis of the bunch signal to obtain bunch-by-bunch and turn-by-turn longitudinal parameters,such as bunch length and synchronous *** bunch signal is obtained using a button electrode with a bandwidth of several *** data acquisition device was a high-speed digital oscilloscope with a sampling rate of more than 10 GS/s,and the single-shot sampling data buffer covered thousands of *** bunch-length and synchronous phase information were extracted via offline calculations using Python *** calibration coefficient of the system was determined using a commercial streak ***,this technique was tested on two different storage rings and successfully captured various longitudinal transient processes during the harmonic cavity debugging process at the Shanghai Synchrotron Radiation Facility(SSRF),and longitudinal instabilities were observed during the single-bunch accumulation process at Hefei Light Source(HLS).For Gaussian-distribution bunches,the uncertainty of the bunch phase obtained using this technique was better than 0.2 ps,and the bunch-length uncertainty was better than 1 *** dynamic range exceeded 10 *** technology is a powerful and versatile beam diagnostic tool that can be conveniently deployed in high-energy electron storage rings.

关键词： Bunch-by-bunch diagnostic Bunch-length measurement Synchronous phase measurement Joint time–frequency-domain analysis Longitudinal instability

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Research on the Encapsulation Device for Lunar Samples

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 104-117页

作者： Yonggang Du Chunyong wang Haoling Li Ying zhou Ming ji Xuesong wang Lanzhou Institute of Physics CASTLanzhou 730000China

The encapsulation of lunar samples is a core research area in the third phase of the Chinese Lunar Exploration *** seal assembly,opening and closing mechanism(OCM),and locking mechanism are the core components of the encapsulation device of the lunar samples,and the requirements of a tight seal,lightweight,and low power make the design of these core components *** this study,a combined sealing assembly,OCM,and locking mechanism were investigated for the *** sealing architecture consists of rubber and an Ag-In alloy,and a theory was built to analyze the *** of the electroplate Au coating on the knife-edge revealed that the hermetic seal can be significantly *** driving principle for coaxial double-helical pairs was investigated and used to design the ***,a locking mechanism was created using an electric initiating explosive device with orifice *** optimizing the design,the output parameters were adjusted to meet the requirements of the lunar *** experimental results showed that the helium leak rate of the test pieces were not more than 5×10^(-11) Pa·m^(3)·s^(-1),the minimum power of the OCM was 0.3 W,and the total weight of the principle prototype was 2.9 *** explosive driven locking mechanism has low *** investigation solved the difficulties in achieving tight seal,light weight,and low power for the lunar explorer,and the results can also be used to explore other extraterrestrial objects in the future.

关键词： Lunar samples Encapsulation Vacuum seal Mechanism

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Underwater Image Classification Based on EfficientnetB0 and Two-Hidden-Layer Random Vector Functional Link

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Journal of Ocean University of China 2024年第2期23卷 392-404页

作者： zhou Zhiyu LIU Mingxuan ji Haodong wang Yaming ZHU Zefei School of Information Science and Technology Zhejiang Sci-Tech UniversityHangzhou 310018China Zhejiang Key Laboratory of DDIMCCP Lishui UniversityLishui 323000China School of Mechanical Engineering Hangzhou Dianzi UniversityHangzhou 310018China

The ocean plays an important role in maintaining the equilibrium of Earth’s ecology and providing humans access to a wealth of *** obtain a high-precision underwater image classification model,we propose a classification model that combines an EfficientnetB0 neural network and a two-hidden-layer random vector functional link network(EfficientnetB0-TRVFL).The features of underwater images were extracted using the EfficientnetB0 neural network pretrained via ImageNet,and a new fully connected layer was trained on the underwater image dataset using the transfer learning *** learning ensures the initial performance of the network and helps in the development of a high-precision classification ***,a TRVFL was proposed to improve the classification property of the *** construction of the two hidden layers exhibited a high accuracy when the same hidden layer nodes were *** parameters of the second hidden layer were obtained using a novel calculation method,which reduced the outcome error to improve the performance instability caused by the random generation of parameters of ***,the TRVFL classifier was used to classify features and obtain classification *** proposed EfficientnetB0-TRVFL classification model achieved 87.28%,74.06%,and 99.59%accuracy on the MLC2008,MLC2009,and Fish-gres datasets,*** best convolutional neural networks and existing methods were stacked up through box plots and Kolmogorov-Smirnov tests,*** increases imply improved systematization properties in underwater image classification *** image classification model offers important performance advantages and better stability compared with existing methods.

关键词： underwater image classification EfficientnetB0 random vector functional link convolutional neural network

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Small Cycles Property of Some Cremer Rational Maps and Polynomials

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Chinese Annals of Mathematics,Series B 2024年第1期45卷 123-136页

作者： Rong FU ji zhou Faculty of Science Yibin UniversityYibin 644000SichuanChina Department of Mathematical Sciences Sichuan Normal UniversityChengdu 610066China

This paper concerns the linearization problem on rational maps of degree d≥2 and polynomials of degree d>2 from the perspective of *** authors introduce a set l_(∞) of irrational numbers and show that if α∈l_(∞),then any rational map is not linearizable and has infinitely many cycles in every neighborhood of the fixed point with multiplier λ=e^(2πiα),Adding more constraints to cubic polynomials,they discuss the above problems by polynomial-like *** the family of polynomials,with the help of Yoccoz's method,they obtain its maximum dimension of the set in which the polynomials are non-linearizable.

关键词： Irrationally indifferent fixed point Linearization problem Small cycles property

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Dielectric response of ANb_(2)O_(6)(A = Zn, Co, Mn, Ni) columbite niobates: From microwave to terahertz

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Journal of Advanced Ceramics 2024年第8期13卷 1189-1197页

作者： Weijia Luo Shun wang Siyong Zheng jining Li Menglong wang Yongzheng Wen ingxia Li ji zhou State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Institute of Laser and Optoelectronics School of Precision Instrument and Opto-Electronics EngineeringTianjin UniversityTianjin 300072China Shandong Inspur Artificial Intelligence Research Institute Co. Ltd.Jinan 250013China School of Microelectronics Tianjin UniversityTianjin 300072China

In the upcoming 6-generation(6G)revolution,the achievement of low power consumption has become a key objective in research concerning terahertz *** an important component of passive devices,there are very few low-loss dielectric ceramics in the terahertz *** elucidate the mechanism of loss and promote the application of microwave dielectric ceramics for future 6G technology(covering microwave and terahertz frequencies),the terahertz responses of ANb_(2)O_(6)(A=Zn,Co,Mn,and Ni)columbite niobates were *** influences of magnetic loss on the Qxf values in the microwave range with different transition metal ions in the A-site were reasonably ***,due to the weakened magnetic relaxation properties in the terahertz range,the samples all exhibited low loss and approximate transparency,especially for MnNb_(2)O_(6) and NiNb_(2)O_(6)(tano<0.01 and absorption coefficient<10 cm^(-1) below 1.2 THz),which subverted the definition of traditional low-loss microwave dielectric ***,based on Mie theory,we designed a prototypical broadband metamaterial reflector to validate the applicability of the ANb_(2)O_(6) system in the terahertz band,which is highly important for the development of terahertz ceramic-based passive devices.

关键词： columbite niobates terahertz response transition metal ions magnetic loss ceramic-based metamaterials

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Light People: Professor Fanglin Bao and his cover story

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Light(Science & Applications) 2024年第6期13卷 1015-1020页

作者： ji wang School of Science Westlake UniversityHangzhouZhejiangPR China

Qu Yuan,a renowned ancient Chinese poet,once pondered in his work Heavenly Inquiry:“If the sun’s light is absent,from where does the radiance of the Hero Flower emanate?”The ability to see clearly in the darkest of nights has long been a sought-after magical power by *** holds not only immense technological significance for computer vision and remote sensing but also profound implications for transcending the dichotomy between day and night in our daily *** Fanglin Bao from Westlake University has made significant breakthroughs in this field,bringing us closer to a world where we can transform night into *** groundbreaking research on Heat-Assisted Detection and Ranging(HADAR)and night vision was featured as the cover story in Nature on July 26,2023.

关键词： bringing breakthrough holds

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