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Chinese Association for the Study of Pain:Expert consensus on chronic postsurgical pain

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World Journal of Clinical Cases 2021年第9期9卷 2090-2099页

作者： Yi-ming liu Yi Feng Yan-Qing liu Yan Lv Yuan-Chang Xiong Ke Ma Xian-Wei Zhang jin-Feng liu Yi jin Hong-Guang Bao min Yan Tao Song Qing liu Department of Algology Peking University People’s HospitalBeijing 100044China Department of Algology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China Department of Algology Air Force Medical University of PLAXi’an 710032Shaanxi ProvinceChina Department of Anesthesiology Changhai HospitalNaval Military Medical UniversityShanghai 200433China Department of Algology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Algology The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Algology Affiliated Jinling HospitalMedical School of Nanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Anesthesiology Nanjing First HospitalNanjing Medical UniversityNanjing 210006Jiangsu ProvinceChina Department of Anesthesiology The Second Affiliated Hospital of Zhejiang University school of MedicineHangzhou 310058Zhejiang ProvinceChina Department of Algology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Algology The Affiliated T.C.M Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

Chronic postsurgical pain is a common surgical complication that severely reduces a patient’s quality of *** perioperative interventions and management strategies have been developed for reducing and managing chronic postsurgical *** the leadership of the Chinese Association for the Study of Pain,an editorial committee was formed for chronic postsurgical pain diagnosis and treatment by experts in relevant *** editorial committee composed the main content and framework of this consensus and established a working *** working group conducted literature review(1989-2020)using key words such as“surgery”,“post-surgical”,“post-operative”,“pain”,“chronic”,and“persistent”in different databases including MEDLINE,EMBASE,PubMed,Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic *** publications in the English language were *** types of literature included systematic reviews,randomized controlled studies,cohort studies and case *** consensus was written based on clinical practice combined with literature *** first draft of the consensus was rigorously reviewed and edited by all the editorial committee experts before being *** level of evidence was assessed by methodological experts based on the Oxford Centre for Evidence-Based Medicine Levels of *** strength of recommendation was evaluated by all editorial committee experts,and the opinions of most experts were adopted as the final *** recommendation level“strong”generally refers to recommendations based on high-level evidence and consistency between clinical behavior and expected *** recommendation level“weak”generally refers to the uncertainty between clinical behavior and expected results based on low-level evidence.

关键词： Chronic postsurgical pain Treatment Interventional Prevention

High-Quality and Strain-Relaxation GaN Epilayer Grown on SiC Substrates Using AIN Buffer and AlGaN Interlayer

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Chinese Physics Letters 2017年第4期34卷 108-111页

作者： Bo-Ting liu Shi-Kuan Guo Ping Ma Jun-Xi Wang jin-min Li Semiconductor Lighting R&D Center Institute of SemiconductorsChinese Academy of SciencesBeijing 100083 College of Materials Science and Opto-Electronic Technology University of Chinese Academy of SciencesBeijing 100049 State Key Laboratory of Solid State Lighting Beijing 100083 Beijing Engineering Research Center for the Third-Generation Semiconductor Materials and Application Beijing 100083

We study the effect of the AlGaN interlayer on structural quality and strain engineering of the GaN films grown on SiC substrates with an AlN buffer layer, hnproved structural quality and tensile stress releasing are realized in unintentionally doped GaN thin films grown on 6H-SiC substrates by metal organic chemical vapor deposition. Using the optimized AlGaN interlayer, we find that the full width at half maximum of x-ray diffraction peaks for GaN decreases dramatically, indicating an improved crystalline quality. Meanwhile, it is revealed that the biaxial tensile stress in the GaN film is significantly reduced from the Raman results. Photoluminescence spectra exhibit a shift of the peak position of the near-band-edge emission, as well as the integrated intensity ratio variation of the near-band-edge emission to the yellow luminescence band. Thus by optimizing the AlGaN interlayer, we could acquire the high-quality and strain-relaxation GaN epilayer with large thickness on SiC substrates.

关键词： AlGaN In High-Quality and Strain-Relaxation GaN Epilayer Grown on SiC Substrates Using AIN Buffer and AlGaN Interlayer SiC AIN

OsBGLU19 and OsBGLU23 regulate disease resistance to bacterial leaf streak in rice

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Journal of Integrative Agriculture 2019年第6期18卷 1199-1210页

作者： LI Bei-bei liu Ying-gao WU Tao WANG ji-peng XIE Gui-rong CHU Zhao-hui DING Xin-hua State Key Laboratory of Crop Biology/Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests Shandong Agricultural University

β-Glucosidase belongs to the glycoside hydrolase I family,which is widely present in multiple species and responds to various biotic and abiotic *** rice,whetherβ-glucosidase is involved in the interaction between plants and microorganisms is not *** this study,we found that the expression of several genes encodingβ-glucosidases,including OsBGLU19 and OsBGLU23,were upregulated after inoculation with Xanthomonas oryzae ***(Xoc)and downregulated after inoculation with *** ***(Xoo).The respective insertion mutants of OsBGLU19 and OsBGLU23,bglu19 and bglu23,were more susceptible to Xoc *** expression of OsAOS2,a key gene in the jasmonic acid signal pathway,was dramatically downregulated after inoculation with Xoc in the bglu19 and bglu23 ***,the expression of downstream disease resistance-related genes,such as OsPR1a,OsPR5 and a key transcription factors OsWRKY72 were obviously *** resistance mediated by OsBGLU19 and OsBGLU23 to bacterial leaf streak is related to disease resistance-related genes above mentioned.

关键词： β-glucosidase OsBGLU19 OsBGLU23 Oryza sativa bacterial leaf streak

Quantitative Assessment of Hepatic Fibrosis by Contrast-enhanced Ultrasonography

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Chinese Medical Sciences Journal 2011年第4期26卷 208-215页

作者： ming-bo Zhang En-ze Qux En-ze Qu ji-Bin liu jin-rui Wang Department of Ultrasound Peking University Third Hospital Beijing 100191 China Inner Mongolia Institute of Ultrasound Erdos 017000 China

Objective To explore the contrast-enhanced ultrasonographic features for quantitative assessment of hepatic fibrosis. Methods 86 patients with chronic viral hepatitis B were enrolled in this study from March 2007 to August 2009. The patients were classified into 5 groups (S0-S4) according to fibrosis stage evaluated with ultrasound guided liver biopsy. New contrast-enhanced ultrasonography (CEUS) features including area under the time-intensity curve (TIC) of portal venous phase/hepatic arterial phase (Qp/Qa) and intensity of portal venous phase/hepatic arterial phase (Ip/Ia) were used to detect the blood supply ratio (portal vein/hepatic artery) in each group. Arrival time of portal vein trunk (Tp) and decreasing rate of TIC (β ) were also analyzed. Results Qp/Qa and Ip/Ia decreased from S0 to S4, while Tp and β increased. These 4 features were significantly correlated with the degree of fibrosis (P<0.001) and were significantly different among the five groups (P<0.001). Sensitivity and specificity of Ip/Ia were 80% and 86% for groups ≥S1, 75% and 86% for groups ≥ S2, 71% and 84% for groups ≥ S3, and 76% and 80% for group S4, respectively. Sensitivity and specificity of Qp/Qa were 70% and 88% for groups ≥ S1, 80% and 76% for groups ≥ S2, 74% and 70% for groups ≥ S3, and 81% and 95% for group S4, respectively. Conclusion Ip/Ia and Qp/Qa could be adopted as reliable, non-invasive features for quantitative assessment of hepatic fibrosis.

关键词： hepatic fibrosis contrast-enhanced ultrasonography quantitative non- invasive

A novel cascaded energy conversion system inducing efficient and precise cancer therapy

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Bioactive Materials 2023年第2期20卷 663-676页

作者： Yong Kang Na Kong Meitong Ou Ying Wang Qicai Xiao Lin Mei Bing liu Liqun Chen Xiaobin Zeng Xiaoyuan ji Center Lab of Longhua Branch and Department of Infectious Disease Shenzhen People’s Hospital(The Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)Shenzhen518020GuangdongChina Academy of Medical Engineering and Translational Medicine Medical CollegeTianjin UniversityTianjin300072China School of Pharmaceutical Sciences(Shenzhen) Sun Yat-sen UniversityGuangzhou510275China Department of Disease Control and Prevention Rocket Force Characteristic Medical Center16 Xinjiekouwai StreetXicheng DistrictBeijing10088China

Cancer therapies based on energy conversion,such as photothermal therapy(PTT,light-to-thermal energy conversion)and photodynamic therapy(PDT,light-to-chemical energy conversion)have attracted extensive attention in preclinical ***,the PTT-related hyperthermia damage to surrounding tissues and shallow penetration of PDT-applied light prevent further advanced clinical ***,we developed a thermoelectric therapy(TET)based on thermoelectric materials constructed p-n heterojunction(SrTiO_(3)/Cu_(2)Se nanoplates)on the principle of light-thermal-electricity-chemical energy *** irradiation and natural cooling-induced the temperature gradient(35-45℃),a self-build-in electric field was constructed and thereby facilitated charges separation in bulk SrTiO_(3)and Cu_(2)***,the contact between SrTiO_(3)(n type)and Cu_(2)Se(p type)constructed another interfacial electric field,further guiding the separated charges to re-locate onto the surfaces of SrTiO_(3)and Cu_(2)*** formation of two electric fields minimized probability of charges *** note,high-performance superoxide radicals and hydroxyl radicals’generation from O_(2)and H_(2)O under catalyzation by separated electrons and holes,led to intracellular ROS burst and cancer cells apoptosis without apparent damage to surrounding *** of bulk and interfacial electric fields in heterojunction for improving charges separation and transfer is also expected to provide a robust strategy for diverse applications.

关键词： Thermoelectric therapy Photothermal therapy Reactive oxygen species p-n heterojunction Energy conversion

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溶液法制备图案化量子点薄膜的研究进展

高等学校化学学报 2020年第3期41卷 401-410页

作者：张敏刘欢北京航空航天大学化学学院

量子点发光二极管(QLED)由于具有显色性好,色纯度高和性能稳定等特点而受到广泛关注,可用于制备具有超薄结构和柔性结构的显示器件.量子点(QDs)层是QLED器件的核心发光层,制备高质量的图案化QD薄膜对于提高QLED器件性能至关重要.本文综... 详细信息

量子点发光二极管(QLED)由于具有显色性好,色纯度高和性能稳定等特点而受到广泛关注,可用于制备具有超薄结构和柔性结构的显示器件.量子点(QDs)层是QLED器件的核心发光层,制备高质量的图案化QD薄膜对于提高QLED器件性能至关重要.本文综述了近年来溶液法制备QD薄膜的研究进展,探讨了目前主要使用的各种溶液法的优势和前景,并对最近新发展的纤维辅助的溶液可控转移制备QD薄膜方法的优势和发展前景进行了评述.

关键词：溶液法薄膜量子点发光二极管器件

Ultrafast,accurate,and robust localization of anisotropic dipoles

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Protein & Cell 2013年第8期4卷 598-606页

作者： Yongdeng Zhang Lusheng Gu Hao Chang Wei ji Yan Chen mingshu Zhang Lu Yang Bei liu Liangyi Chen Tao Xu College of Life Science and Technology Huazhong University of Science and TechnologyWuhan 430074China National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China School of Life Sciences University of Science and Technology of ChinaHefei 230026China University of Chinese Academy of Sciences Beijing 100049China Laboratory of Cell Secretion and Metabolism Institute of Molecular MedicinePeking UniversityBeijing 100871China

The resolution of single molecule localization imaging techniques largely depends on the precision of localization ***,the commonly used Gaussian function is not appropriate for anisotropic dipoles because it is not the true point spread *** derived the theoretical point spread function of tilted dipoles with restricted mobility and developed an algorithm based on an artifi cial neural network for estimating the localization,orientation and mobility of individual *** with fi tting-based methods,our algorithm demonstrated ultrafast speed and higher accuracy,reduced sensitivity to defocusing,strong robustness and adaptability,making it an optimal choice for both two-dimensional and threedimensional super-resolution imaging analysis.

关键词： point spread function restricted mobility artifi cial neural network super-resolution imaging

山西省国家A级旅游景区空间分布影响因素研究

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地理学报 2020年第4期75卷 878-888页

作者：刘敏郝炜太原师范学院地理科学学院晋中030619

基于GIS空间分析技术与地理探测器(Geodetector)方法,使用旅游政务网、地理空间数据云、政府报告和统计年鉴相关数据,对2001-2017年间影响山西省国家A级旅游景区空间分布的影响因素进行了分析,包含社会政治因素(相关政策、常驻人口、交... 详细信息

基于GIS空间分析技术与地理探测器(Geodetector)方法,使用旅游政务网、地理空间数据云、政府报告和统计年鉴相关数据,对2001-2017年间影响山西省国家A级旅游景区空间分布的影响因素进行了分析,包含社会政治因素(相关政策、常驻人口、交通状况)、经济产业因素(三产占比、旅游收入、生产总值)和自然环境因素(海拔高度、河流水系、平均气温)。结果表明:①社会政治因素和经济产业因素变化较大,属于动态影响因素,自然环境因素变化较小,属于静态影响因素;②相关政策、常住人口、交通状况、旅游收入、生产总值5个三级动态影响因素的影响能力值从2001-2017年间不断加强,而三产占比三级动态影响因素呈现波动下降,海拔高度、河流水系、平均气温3个三级静态影响因素的影响能力值变化较平稳;③从演化过程来看,2001-2017年间社会政治因素影响能力值逐年增加,是影响程度最高的二级影响因素,经济产业因素发展为影响程度第二的二级影响因素,自然环境因素发展为影响程度最小的二级影响因素。结果可为合理评价和指导区域旅游业全面发展提供有力支撑,促进旅游业发展,为旅游景区空间结构优化和旅游产业升级提供科学依据。

关键词：国家A级旅游景区地理探测器空间分布演化影响因素山西省

Metatranscriptome of the protistan community in Reticufitermes flaviceps

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Insect Science 2016年第4期23卷 543-547页

作者： Xiao-jing liu min Che Lei Xie Shuai Zhan Zhi-Hua Zhou Yong-Ping Huang Qian Wang Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai College of Science Air Force Engineering University Xi'an Institute Pasteur of Shanghai Chinese Academy of Sciences Shanghai China

The hindgut of lower termites harbors various symbiotic protists, which per- form varied functions in lignocellulose decomposition. As termites are social insects, the species and numbers of these flagellated protists in the termite gut vary among the different castes. Juvenile hormones （JHs） can regulate caste differentiation in termites. In this study, we used the juvenile hormone analog fenoxycarh to induce termite workers （Reticulitermesflaviceps） to differentiate into pre-soldiers. A metatranscriptomic investigation of the protistan community was then performed by 454 pyrosequencing. From a thorough analysis based on 597 312 generated reads, we found that the starch and sucrose metabolism pathway was the most abundant pathway across the metatranscriptome. The current study demonstrates that the metatranscriptome of the protistan community in termites contains an abundance of lignocellulase, which plays a vital role in termite nutrition.

关键词： juvenile hormone analogues metatranscriptome protest Reticulitermes flaviceps lignocellulase