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Real drive cycles analysis by ordered power methodology applied to fuel consumption,C0_(2),NO_(x) and PM emissions estimation

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Frontiers of Environmental Science & Engineering 2021年第1期15卷 77-90页

作者： Pol Masclans Abello Vicente Medina Iglesias M.Antonia de los Santos Lopez jesus alvarez-florez Center for Engines and Heat Installation Research(CREMIT-UPC).Universitat Politecnica de Catalunya-BarcelonaTech.Av.Diagonal 547(ETSEIB)08028 Barcelona Spain Department of Thermal Machinery of Universitat Politecnica de Catalunya-BarcelonaTech and CREMIT-UPC.-BarcelonaTech.Av.Diagonal 547(ETSEIB)08028 Barcelona Spain 3 Department of Mechanical Engineering of Universitat Politecnica de Catalunya-BarcelonaTech and CREMIT-UPC.-BarcelonaTech.Av.Diagonal 547(ETSEIB)08028 Barcelona Spain

In this work three fuel consumption and exhaust emission models,ADVISOR,VT-MICRO and the European Environmental Agency Emission factors,have been used to obtain fuel consumption(FC)and exhaust *** models have been used at micro-scale,using the two signal treatment methods *** manuscript presents:1)a methodology to collect data in real urban driving cycles,2)an estimation of FC and tailpipe emissions using some available models in literature,and 3)a novel analysis of the results based on delivered wheel *** results include Fuel Consumption(FC),CO_(2),NO_(x) and PM_(10) emissions,which are derived from the three *** the first part of the paper we present a new procedure for incomplete drive cycle data treatment,which is necessary for real drive cycle acquisition in high density *** the models are used to obtain second by second FC and exhaust ***,a new methodology named Cycle Analysis by Ordered Power(CAbOP)is presented and used to compare the *** method consists in the re-ordering of time dependant data,considering the wheel mechanical power domain instead of the standard time *** new strategy allows the 5 situations in drive cycles to be clearly visualized:hard breaking zone,slowdowns,idle or stop zone,sustained speed zone and acceleration *** complete methodology is applied in two real drive cycles surveyed in Barcelona(Spain)and the results are compared with a standardized WLTC urban cycle.

关键词： Cycle Analysis by Ordered Power(CAbOP) Micro and macro models Real drive cycle NO_(x)/PM_(10)/CO_(2)emissions Wheel mechanical power domain Worldwide Harmonized Light-Duty Vehicles Test Cycle(WLTC)

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Unraveling the Biochemical and Molecular Networks Involved in Maize Cell Habituation to the Cellulose Biosynthesis Inhibitor Dichlobenil

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Molecular Plant 2010年第5期3卷 842-853页

作者： Hugo Melida Antonio Encina jesus alvarez Jose Luis Acebes David Caparros-Ruiz Area de Fisiologia Vegetal Facultad de CC. Biologicas y Ambientales Universidad de Leon E-24071 Leon Spain Centre de Recerca en AgriGen6mica (Consorci CSIC-IRTA-UAB) Jordi Girona 18-26 E-08034 Barcelona Spain

The biochemical and molecular processes involved in the habituation of maize cells to growth in the presence of the cellulose biosynthesis inhibitor dichlobenil （DCB） were investigated. DCB affects the synthesis of cellulose both in active and stationary growth phases and alters the expression of several CesA genes. Of these, ZmCesA5 and ZmCesA7 seem to play a major role in habituating cells to growth in the presence of DCB. As a consequence of the reduction in cellulose, the expression of several genes involved in the synthesis of hydroxycinnamates is increased, resulting in cell walls with higher levels of ferulic and p-coumaric acids. A proteomic analysis revealed that habituation to DCB is linked to modifications in several metabolic pathways. Finally, habituated cells present a reduction in glutathione S-transferase detoxifying activity and antioxidant activities. Plant cell adaptation to the disturbance of such a crucial process as cellulose biosynthesis requires changes in several metabolic networks, in order to modify cell wall architecture and metabolism, and survive in the presence of the inhibitor. Some of these modifications are described in this paper.

关键词： Abiotic/environmental stress acclimation--physiological cell walls maize cellulose dichlobenil phenylpropanoid.

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Changes in Cinnamic Acid Derivatives Associated with the Habituation of Maize Cells to Dichlobenil

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Molecular Plant 2011年第5期4卷 869-878页

作者： Hugo Melida jesus alvarez Jose Luis Acebes Antonio Encina Stephen C. Fry Area de Fisiologia Vegetal Facultad de CC Biologicas y Ambientales Universidad de Leon E-24071 Leon Spain Edinburgh Cell Wall Group Institute of Molecular Plant Sciences School of Biological Sciences University of Edinburgh Daniel Rutherford Building The King＇s Buildings Edinburgh EH9 3JH UK

The habituation of cell cultures to cellulose biosynthesis inhibitors such as dichlobenil （DCB） represents a valu- able tool to improve our knowledge of the mechanisms involved in plant cell wall structural plasticity. Maize cell lines habituated to lethal concentrations of DCB were able to grow through the acquisition of a modified cell wall in which cellulose was partially replaced by a more extensive network of arabinoxylans. The aim of this work was to investigate the phenolic metabolism of non-habituated and DCB-habituated maize cell cultures. Maize cell cultures were fed [14C]cinnamate and the fate of the radioactivity in different intra-protoplasmic and wall-localized fractions throughout the culture cycle was analyzed by autoradiography and scintillation counting. Non-habituated and habituated cultures did not markedly differ in their ability to uptake exogenous [14C]cinnamic acid. However, interesting differences were found in the radiolabeling of low- and high-Mr metabolites. Habituated cultures displayed a higher number and amount of radiola-beled low-Mr compounds, which could act as reserves later used for polysaccharide feruloylation. DCB-habituated cultures were highly enriched in esterified [14C]dehydrodiferulates and larger coupling products. In conclusion, an extensive and early cross-linking of hydroxycinnamates was observed in DCB-habituated cultures, probably strengthening their cellulose-deficient walls.

关键词： Cell wall Zea mays maize dichlobenil DCB dehydrodiferulate ferulate cinnamic acid.

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Full-thickness scleral incisions technique for the treatment of a cyclodialysis cleft following ab interno trabeculotomy

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International Journal of Ophthalmology(English edition) 2019年第10期12卷 1662-1665页

作者： Daniela alvarez-Ascencio jesus Jimenez-Roman Rafael Castaneda-Diez Gabriel Lazcano-Gomez Glaucoma Department Asociacion Para Evitar la Ceguera en Mexico

Dear Editor, I am *** alvarez-AscenciofromtheGlaucoma Department at Asociacion Para Evitar la Ceguera (APEC)in Mexico City, Mexico. I write to present a successful case of cyclodyalisis repair in a direct visualizatio... 详细信息

关键词： CC OS UBM Full-thickness scleral incisions technique for the treatment of a yclodialysis cleft following ab interno trabeculotomy

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Gene Therapy of Cancer:Induction of Anti-Tumor Immunity

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Cellular & Molecular Immunology 2004年第2期1卷 105-111页

作者： jesus Prieto Division

Many malignancies lack satisfactory treatment and new therapeutic options are urgently *** therapy is a new modality to treat both inherited and acquired diseases based on the transfer of genetic material to the *** gene therapy strategies against cancers have been developed.A considerable number of preclinical studies indicate that a great variety of cancers are amenable to gene *** these strategies, induction of anti-tumor immunity is the most promising *** therapy with cytokines has reached unprecedented success in preclinical models of *** rather than additive effects have been demonstrated by combination of gene transfer of cytokines/chemokines,costimulatory molecules or adoptive cell *** progress in vector technology and in imaging techniques allowing in vivo assessment of gene expression will facilitate the development of clinical applications of gene therapy,a procedure which may have a notorious impact in the management of cancers lacking effective *** & Molecular Immunology.2004;1(2):105-111.

关键词： gene therapy anti-tumor immunity cytokines costimulatory molecules dendritic cell

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Integrating Levels of Hierarchical Organization in Porous Organic Molecular Materials

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Nano-Micro Letters 2024年第5期16卷 134-153页

作者： jesus Ferrando‑Soria Antonio Fernandez Instituto de Ciencia Molecular(ICMol) Universidad de Valencia46980 ValenciaSpain School of Science Loughborough UniversityLoughborough LE113TUUK

Porous organic molecular materials(POMMs)are an emergent class of molecular-based materials characterized by the formation of extended porous frameworks,mainly held by non-covalent *** represent a variety of chemical families,such as hydrogen-bonded organic frameworks,porous organic salts,porous organic cages,C-H···πmicroporous crystals,supramolecular organic frameworks,π-organic frameworks,halogen-bonded organic framework,and intrinsically porous molecular *** some porous materials such as zeolites and metal organic frameworks,the integration of multiscale has been adopted to build materials with multifunctionality and optimized ***,considering the significant role of hierarchy in porous materials and the growing importance of POMMs in the realm of synthetic porous materials,we consider it appropriate to dedicate for the first time a critical review covering both ***,we will provide a summary of literature examples showcasing hierarchical POMMs,with a focus on their main synthetic approaches,applications,and the advantages brought forth by introducing hierarchy.

关键词： Porous organic molecular materials Hierarchy Hydrogen-bonded organic frameworks Porous cages Fullerene

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Episcleral brachytherapy as an effective alternative in vasoproliferative tumors

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International Journal of Ophthalmology(English edition) 2018年第12期11卷 2017-2020页

作者： Marta Para Prieto Maria Antonia Saornil jesus Maria de Frutos Baraja Ciro Garcia alvarez Patrieia Diezhandino Garcia Francisco Lopez Lara Intraocular Tumors Unit Ophthalmology &Radiotherapy departmentsHospital Clinico UniversitarioValladolid 47005 Spain

The aim of this study is to assess the results of episcleral brachytherapy as treatment of retinal vasoproliferative tumors(RVTs) in a referral Intraocular Tumors Unit(ITU). A retrospective review of all patients diagnosed with vasoproliferative tumors of the retina and treated with episcleral brachytherapy in the ITU, University Hospital of Valladolid between 2009 and 2015 was done. Five patients accomplished the inclusion criteria. All of them presented associated exudation and secondary retinal detachments(RD). Four patients had received prior treatments. Decreased tumor size and exudation regression was found in all cases after treatment. Visual acuity remained stable or increased in all patients. No recurrences have been found after twelve-months follow up. The results of the present study suggest that episcleral brachytherapy is an efficient and safe option in the management of vasoproliferative tumors, especially when large tumor or extensive subretinal fluid is present. In these cases episcleral brachytherapy could be considered as a first line treatment.

关键词： episcleral brachytherapy retinal vasoproliferative tumors

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Pricing and Valuation of Intangible Assets

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Journal of Modern Accounting and Auditing 2012年第12期8卷 1780-1788页

作者： jesus Timoteo alvarez Sonia A. Ferruz Gonzailez jesus Calzadilla Daguerre Complutense University of Madrid Madrid Spain Polytechnic University of Madrid Madrid Spain

Intangible assets are parts of the companies＇ balance sheet, but given their intangible nature, they cannot be qualified as financial assets as other incomes can be. Therefore, the valuation, even if reflected in accounting reports, is far from objective, and each company considers it in accordance with their sectors or auditors. Auditors, consultants, and business schools are developing alternative tools for measuring these assets, but there is not a consensus formula that quantifies the business value of intangibles. In recent years, communication analysts and consultants have developed brand valuation and reputation methodologies, which are starting to have a relative weight in business management. The proposed research work is a review of the current methodologies of reputation valuation as a starting point for creating a reference model formula for the valuation of intangibles that provide professionals and experts in the field with a worldwide recognized tool.

关键词： intangible assets accounting valuation of intangibles intangibles and reputation intangible communication reputation management

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Effect of magnesium on the aluminothermic reduction rate of zinc oxide obtained from spent alkaline battery anodes for the preparation of Al–Zn–Mg alloys

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International Journal of Minerals,Metallurgy and Materials 2016年第4期23卷 458-465页

作者： Rocio Ochoa Alfredo Flores jesus Torres Cinvestav-Saltillo

The aluminothermic reduction of zinc oxide（ZnO） from alkaline battery anodes using molten Al may be a good option for the elaboration of secondary 7000-series alloys. This process is affected by the initial content of Mg within molten Al, which decreases the surface tension of the molten metal and conversely increases the wettability of ZnO particles. The effect of initial Mg concentration on the aluminothermic reduction rate of ZnO was analyzed at the following values： 0.90wt%, 1.20wt%, 4.00t%, 4.25wt%, and 4.40wt%. The ZnO particles were incorporated by mechanical agitation using a graphite paddle inside a bath of molten Al maintained at a constant temperature of 1123 K and at a constant agitation speed of 250 r/min, the treatment time was 240 min and the ZnO particle size was 450？500 mesh. The results show an increase in Zn concentration in the prepared alloys up to 5.43wt% for the highest initial concentration of Mg. The reaction products obtained were characterized by scanning electron microscopy and X-ray diffraction, and the efficiency of the reaction was measured on the basis of the different concentrations of Mg studied.

关键词： aluminothermic reduction alkaline batteries zinc oxide waste utilization aluminum zinc magnesium alloys

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Genetic factors associated with the development of inflammatory bowel disease

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World Journal of Gastroenterology 2007年第42期13卷 5594-5597页

作者： jesus K Yamamoto-Furusho Inflammatory Bowel DiseaseClinic Department of Gastroenterology Instituto Nacional deCiencias Médicas y Nutrición Vasco de Quiroga 15 ColoniaSección XVI Tlalpan C.P. 14000 México D.F. México

Crohn's disease(CD)and ulcerative colitis(UC)are complex polygenic disorders,characterized by several genes together with environmental factors contributing to the development of inflammatory bowel disease(IBD).Recent advances in research on genetic susceptibility have allowed the identification of diverse genes at different levels:(1)Innate immunity;(2)Antigen presentation molecules;(3)Epithelial integrity;(4)Drug transporter;(5)Cell *** application of genetic testing into clinical practice is close and all genetic markers may have several clinical implications:prediction of disease phenotype,molecular classification,prevention of complications,and prognosis.

关键词： Genetic Susceptibility Inflammatory bowel disease Ulcerative colitis Crohn's disease

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