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Role of N-formyl peptide receptor 2 in germinal matrix hemorrhage:an intrinsic review of a hematoma resolving pathway

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Neural Regeneration Research 2024年第2期19卷 350-354页

作者： jerry Flores Jiping Tang Department of Physiology&Pharmacology Loma Linda University School of MedicineLoma LindaCAUSA

Germinal matrix hemorrhage is one of the leading causes of morbidity,mortality,and acquired infantile hydrocephalus in preterm infants in the United States,with little progress made in its clinical *** clots have been shown to elicit secondary brain injury after germinal matrix hemorrhage,by disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage causing post-hemorrhagic hydrocephalus *** evidence suggests that rapid hematoma resolution is necessary to improve neurological outcomes after hemorrhagic *** articles have demonstrated the beneficial effects of stimulating the polarization of microglia cells into the M2 phenotype,as it has been suggested that they play an essential role in the rapid phagocytosis of the blood clot after hemorrhagic models of stroke.N-formyl peptide receptor 2(FPR2),a G-protein-coupled receptor,has been shown to be neuroprotective after ***2 activation has been associated with the upregulation of phagocytic macrophage clearance,yet its mechanism has not been fully *** literature suggests that FPR2 may play a role in the stimulation of scavenger receptor *** receptor cD36 plays a vital role in microglia phagocytic blood clot clearance after germinal matrix ***2 has been shown to phosphorylate extracellular-signal-regulated kinase 1/2(ERK1/2),which then promotes the transcription of the dual-specificity protein phosphatase 1(DUSP1)*** this review,we present an intrinsic outline of the main components involved in FPR2 stimulation and hematoma resolution after germinal matrix hemorrhage.

关键词： AnxA1 FPR2 GMH hematoma resolution hemorrhagic stroke M1 M2 microglia polarization microglia phagocytosis

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IDS-INT:Intrusion detection system using transformer-based transfer learning for imbalanced network traffic

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Digital communications and Networks 2024年第1期10卷 190-204页

作者： Farhan Ullah Shamsher Ullah Gautam Srivastava jerry chun-Wei Lin School of Software Northwestern Polytechnical UniversityXian710072ShaanxiChina Knowledge Unit of Systems and Technology University of Management and TechnologySialkot 51040Pakistan Department of Math and computer Science Brandon UniversityBrandonMB R7A 6A9Canada Department of computer Science and Math Lebanese American UniversityBeirut1102Lebanon Western Norway University of Applied Sciences BergenNorway Research centre for Interneural computing China Medical UniversityTaichungTaiwanChina

A network intrusion detection system is critical for cyber security against llegitimate *** terms of feature perspectives,network traffic may include a variety of elements such as attack reference,attack type,a subcategory of attack,host information,malicious scripts,*** terms of network perspectives,network traffic may contain an imbalanced number of harmful attacks when compared to normal *** is challenging to identify a specific attack due to complex features and data imbalance *** address these issues,this paper proposes an Intrusion Detection System using transformer-based transfer learning for Imbalanced Network Traffic(IDS-INT).IDS-INT uses transformer-based transfer learning to learn feature interactions in both network feature representation and imbalanced ***,detailed information about each type of attack is gathered from network interaction descriptions,which include network nodes,attack type,reference,host information,***,the transformer-based transfer learning approach is developed to learn detailed feature representation using their semantic ***,the Synthetic Minority Oversampling Technique(SMOTE)is implemented to balance abnormal traffic and detect minority ***,the convolution Neural Network(cNN)model is designed to extract deep features from the balanced network ***,the hybrid approach of the cNN-Long Short-Term Memory(cNN-LSTM)model is developed to detect different types of attacks from the deep *** experiments are conducted to test the proposed approach using three standard datasets,i.e.,UNsWNB15,cIc-IDS2017,and *** explainable AI approach is implemented to interpret the proposed method and develop a trustable model.

关键词： Network intrusion detection Transfer learning Features extraction Imbalance data Explainable AI cybersecurity

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Aerodynamics of a Tandem-Bladed Axial compressor Rotor under circumferential Distortion at Different Rotational Speeds

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Journal of Thermal Science 2024年第4期33卷 1340-1356页

作者： Amit KUMAR jerry T.JOHN A.M.PRADEEP R.A.DAKKERMANS Dragan KOZULOVIc Department of Aerospace Engineering Indian Institute of Technology BombayMumbai400076India Department of Automotive and Aeronautical Engineering Hamburg University of Applied Sciences20099HamburgGermany Institute of Jet Propulsion Bundeswehr University Munich85577NeubibergGermany

For most aircraft engines,inflow distortion is *** distortion is known to degrade the aerodynamic performance and stable operating limits of a *** rotor configuration is an arrangement that effectively controls the growth of the boundary layer over the suction surface of the ***,a higher total pressure rise can be achieved through this unconventional design approach involving the splitting of the blade into forward and aft *** is expected that the effect of inlet flow distortion would be more severe for a tandem-rotor design due to the greater flow turning inherent in such ***,this aspect needs to be thoroughly *** present study discusses the effect of circumferential distortion on the tandem-rotor at different rotational ***-annulus RANS simulations using ANSYS cFX are used in the present *** performance of the rotor at a particular flow coefficient and different rotational speeds is *** total pressure and efficiency are observed to drop at lower mass flow rates under the influence of circumferential *** loss region in each blade passage is mainly associated with the blade wake,tip leakage vortex,secondary flow,and boundary ***,their contribution varies from passage to passage,particularly in the distorted *** the lower span,the wake width is found to be higher than that at a higher *** to the redistribution of the mass flow,the circumferential extent reduces at a higher *** the undistorted sector,the strength of the tip leakage vortex is significantly higher at the design rotational speed than at lower *** distortion near the tip region promotes an early vortex breakdown even at the design operating *** adversely affects the total pressure,efficiency,and stall *** clean flow conditions,this phenomenon is only observed near the stall *** the design operating condition,the breakdown of the forward rotor tip l

关键词： tandem rotor circumferential distortion loss tip leakage vortex vortex breakdown diffusion factor aerodynamics of compressor blade

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Analysis of Deep Ritz Methods for Semilinear Elliptic Equations

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NUMERIcAL MATHEMATIcS-THEORY METHODS AND APPLIcATIONS 2024年第1期17卷 181-209页

作者： chen, Mo Jiao, Yuling Lu, Xiliang Song, Pengcheng Wang, Fengru Yang, jerry Zhijian Wuhan Univ Sch Math & Stat 299 Ba Yi Rd Wuhan 430072 Peoples R China Wuhan Univ Hubei Key Lab Computat Sci 299 Ba Yi Rd Wuhan 430072 Peoples R China

In this paper, we propose a method for solving semilinear elliptical equations using a ResNet with ReLU2 activations. Firstly, we present a comprehensive formulation based on the penalized variational form of the elliptical equations. We then apply the Deep Ritz Method, which works for a wide range of equations. We obtain an upper bound on the errors between the acquired solutions and the true solutions in terms of the depth D, width W of the ReLU2 ResNet, and the number of training samples n. Our simulation results demonstrate that our method can effectively overcome the curse of dimensionality and validate the theoretical results.

关键词： Semilinear elliptic equations Deep Ritz method ReLU2 ResNet convergence rate PARTIAL-DIFFERENTIAL-EQUATIONS INFORMED NEURAL-NETWORKS MONTE-cARLO NUMERIcAL-SOLUTION cONVERGENcE ALGORITHM

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Responses of growth performance,antioxidant function,small intestinal morphology and mRNA expression of jejunal tight junction protein to dietary iron in yellow-feathered broilers

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Journal of Integrative Agriculture 2024年第4期23卷 1329-1337页

作者： Kaiwen Lei Hao Wu jerry W Spears Xi Lin Xi Wang Xue Bai Yanling Huang Key Laboratory of Animal Science of State Ethnic Affairs commission Southwest Minzu UniversityChengdu 610041China Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Southwest Minzu UniversityChengdu 610041China Department of Animal Science North Carolina State UniversityRaleighNC 27695-7621USA

This study aimed to investigate the dose-effect of iron on growth performance,antioxidant *** morphology,and mRNA expression of jejunal tight junction protein in 1-to21-d-old yellow-feathered broilers.A total of 7201-d-old yellow-feathered maleb roilers were allocated to 9 treatments with 8 replicate cages of 10 birds per *** dietary treatments were consisted of a basal diet(contained 79.6 mg Fe kg^(-1))supplemented with 0,20,40,60,80,160,320,640,and 1,280 mg Fe kg^(-1)in the form of FeSO_(4)·7H_(2)*** with the birds in the control group,birds supplemented with 20mg Fe kg^(-1)had higher average daily gain(ADG)(Pcantly decreased ADG(Pcompared with supplementation of 20mg Fe kg^(-1).Malondialdehyde(MDA)concentration in plasma and duodenum increased linearly(Pconcentration in liver and jejunum increased linearly(Pcally(Pcreased dietary Fe *** villus height(VH)in duodenum and jejunum,and the ratio of villus height to crypt depth(V/c)in duodenum decreased linearly(P?0.05)as dietary *** dietary Fe increased,the jejunal relative mRNA abundance of claudin-1 decreased linearly(P=0.001),but the jejunal relative mRNA abundance of zona occludens-1(ZO-1)and occludin decreased linearly(P?0.05)or quadratically(P?0.05).compared with the supplementation of 20 mg Fe kg^(-1),the supplementation of640 mg Fe kg^(-1)or higher increased(P?0.05)MDA concentrations in plasma,duodenum,and jejunum,decreased VH in the duodenum and jejunum,and the addition of 1,280 mg Fe kg^(-1)reduced(P?0.05)the jejunal tight junction protein(claudin-1,ZO-1,occludin)mRNA *** summary,640 mg of supplemental Fe kg^(-1)or greater was associated with decreased growth performance,increased oxidative stress,disrupted intestinal morphology,and reduced mRNA expression of jejunal tight junction protein.

关键词： iron yellow-feathered broiler antioxidant function intestinal morphology tight junction protein

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Method for prevention and control of spontaneous combustion of coal seam and its application in mining field

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International Journal of Mining Science and Technology 2017年第5期27卷 839-846页

作者： Wei Lu Ying-Jiazi cao jerry c.Tien college of Mining and Safety Engineering Shandong University of Science & Technology Department of civil Engineering Monash University

Spontaneous combustion of coal seam has been and continues to be a big problem in coal mines. It could pose great threat to the safety of the whole mine and all miners, especially when it occurs in or nearby coal mines. Besides, environment of area surrounded mines during combustion can be threatened where large amount of toxic gases including cO_2, cO, SO_2 and H_2S can be leased by fire in mine. Hence, it is important and significant for scholars to study the controlling and preventing of the coal seam fire. In this paper, the complicated reasons for the occurrence and development of spontaneous combustion in coal seam are analysed and different models under various air leakage situations are built as well. Based on the model and approximately calculation, the difficulty of fire extinguishment in coal seam is pointed out as the difficulty and poor effect to remove the large amount of heat released. Detailed measurements about backfilling and case analyses are also provided on the basis of the recent ten years' practice of controlling spontaneous combustion in coal seams in china. A technical fire prevention and control method has been concluded as five steps including detection, prevention, sealing, injection and pressure adjustment. However, various backfill materials require different application and environmental factors, so in this paper, analyses and discussion about the effect and engineering application of prevention of spontaneous combustion are provided according to different backfilling technologies and methods. Once the aforementioned fire prevention can be widely applied and regulated in mines, green mining will be achievable concerning mine fire prevention and control.

关键词： Spontaneous combustion of coal Prevention and control Pressure adjustment Mining field

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chemical Determination of Base Status Metals in Soil Sediments and Particulate Matter in Wellington Industrial Estate Location

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Open Journal of Applied Sciences 2024年第5期14卷 1338-1352页

作者： Richard Tamba Simbo jerry Yeke Paye Fayia Francis Nyuma Department of chemistry School of Basic Sciences Njala University Freetown Sierra Leone Department of Science and Mathematics College of Arts and Sciences William V.S. Tubman University Harper Liberia Department of Fisheries and Science Thomas J.R Faulkner College of Science and Technology University of Liberia Monrovia Liberia

This research study explored the levels of base status metals in soil sediments and particulate matter in the wellington industrial estate location;the main objectives were to: 1) determine sodium and potassium, 2) determine calcium and magnesium, 3) determine available iron. The following hypotheses were put forward;H0a: there is no significant difference in the concentration levels between ca and Mg in the study area, H1a: there is significant difference in the concentration levels between ca and Mg in the study area, H0b: there is no significant difference in the concentration levels between Na and K in the study area, H1b: there is significant difference in the concentration levels between Na and K in the study area. Six locations were used to collect samples with the aid of scoop and gravel free auger (at varying depths of 0 - 5 cm and 5 - 10 cm) which are Wellington Industrial Estate Area 1 (WIEL 1), (WIEL 2), (WIEL 3), (WIEL 4), (WIEL 5), (WIEL 6);the samples were given laboratory treatment. Flame photometer, EDTA, and Spectrophotometer were used in the determinations of sodium and potassium, calcium and magnesium, and available iron respectively. The results indicated that levels of potassium were in medium range (moderately high);sodium levels were generally low when compared to Brook’s classification table. Levels of calcium were generally low and those of magnesium were moderate based on Brook’s table of classification. Levels of available iron which fall within the range of Quijano-Guerta (2003) were high;this implies such levels can lead to toxicity. In all locations, there was decrease in the levels of each metal in the samples with (5 - 10 cm) depth.

关键词： Deposition Environment Particulate Sediment Toxicity

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涨跌停制度变革、股票流动性与资本市场表现

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金融研究 2024年第3期 113-131页

作者：赵家悦卢锐柳建华 jerry cao 中山大学商学院广东深圳518107 中山大学管理学院/现代会计与账务研究中心广东广州510275 中山大学岭南学院广东广州510275 香港恒生大学商学院中国香港999077

完善的资本市场基础制度,是建设高质量资本市场的根本保障。本文以创业板放宽涨跌幅限制至20%作为准自然实验,细致研究涨跌停制度变革的政策效应。首先,我们意外地发现,放宽涨跌幅限制后,触及10%涨跌幅的样本比例反而明显减少,且股价受... 详细信息

完善的资本市场基础制度,是建设高质量资本市场的根本保障。本文以创业板放宽涨跌幅限制至20%作为准自然实验,细致研究涨跌停制度变革的政策效应。首先,我们意外地发现,放宽涨跌幅限制后,触及10%涨跌幅的样本比例反而明显减少,且股价受到冲击后的表现也更加平稳。然后,我们考察股票流动性这一底层核心要素发现,实施涨跌停制度变革后,股票流动性显著提升:具体而言,每亿元成交量所引发的股价冲击幅度下降了大约0.73个百分点,相当于在同等规模的市场成交下,股票价格所受到的冲击减小了近五分之一。机制分析表明,涨跌停制度变革能够有效减少投资者的“羊群行为”,且有助于抑制过度投机,继而改善股票流动性。最后,对政策效果进行拓展性分析发现,涨跌停制度变革提高了市场定价效率,但并不会提升市场风险,从而回应了投资者对于该政策可能加剧市场风险的关切。本文的研究结果证实了涨跌停制度变革的适当性与必要性,表明这一变革符合我国发展高质量资本市场的长期目标,并为进一步深化资本市场改革提供了经验证据。

关键词：涨跌停制度变革股票流动性投资者行为市场定价效率流动性风险

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DPM simulation in an underground entry: comparison between particle and species models

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International Journal of Mining Science and Technology 2016年第3期26卷 487-494页

作者： Thiruvengadam Magesh Zheng Yi Tien jerry c. Department of Mining & Nuclear Engineering Missouri University of Science & Technology Division of Mining and Resources Engineering Department of Civil Engineering Monash University

The diesel particulate matter(DPM) emission from diesel powered equipment in underground mines can cause health hazards including cancer to the miners. The understanding of the DPM propagation pattern under realistic mining condition is required for selecting proper DPM control strategies and to improve working practices in underground mines. In this paper, three dimensional simulations of DPM emission from the exhaust tail pipe of a load-haul-dump(LHD) vehicle and its subsequent distribution inside an isolated zone in the typical underground mine are carried out using two different solution models available in Ansys Fluent. The incoming fresh air into the isolated zone is treated as a continuous phase and DPM is treated either as a continuous phase(gas) or as a secondary discrete phase(particle). Species transport model is used when DPM is treated as gas and discrete phase model is used when DPM is assumed to behave like a particle. The distributions of DPM concentration inside the isolated zone obtained from each method are presented and compared. From the comparison results, an accurate and economical solution technique for DPM evaluation can be selected.

关键词： cFD Dead-end DPM Discrete phase model Species transport model

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Variable retention harvesting in the Douglas-fir region

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Ecological Processes 2020年第1期9卷 83-92页

作者： jerry F.Franklin Daniel c.Donato School of Environmental and Forest Science College of the EnvironmentUniversity of WashingtonSeattleWA 98195USA Washington Department of Natural Resources OlympiaWA 98504USA

Variable retention harvesting evolved in the Douglas-fir region of the Pacific Northwest gradually in response to increasing dissatisfaction with the ecological consequences of clear-cutting,from the standpoint of wildlife habitat and other important forest *** is a harvesting technique that can provide for retention(continuity)of such structures as large and old live trees,snags,and *** retention is based on the natural model of the biological legacies that are typically left behind following natural disturbances,such as wildfire,wind,and *** retention is also an important technique for fulfilling the first silvicultural principle of ecological forestry,that of providing for continuity in structure,function,and composition between forest *** history and current application of variable retention approaches on forests in western Washington and Oregon states(USA),where many of the fundamental concepts were first developed and applied,is described in this article.

关键词： Biological legacies Ecological forestry Biodiversity conservation Long-term sustainability Washington and Oregon states

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