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Role of N-formyl peptide receptor 2 in germinal matrix hemorrhage:an intrinsic review of a hematoma resolving pathway

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Neural Regeneration Research 2024年第2期19卷 350-354页

作者： jerry Flores Jiping Tang Department of Physiology&Pharmacology Loma Linda University School of MedicineLoma LindaCAUSA

Germinal matrix hemorrhage is one of the leading causes of morbidity,mortality,and acquired infantile hydrocephalus in preterm infants in the United States,with little progress made in its clinical *** clots have been shown to elicit secondary brain injury after germinal matrix hemorrhage,by disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage causing post-hemorrhagic hydrocephalus *** evidence suggests that rapid hematoma resolution is necessary to improve neurological outcomes after hemorrhagic *** articles have demonstrated the beneficial effects of stimulating the polarization of microglia cells into the M2 phenotype,as it has been suggested that they play an essential role in the rapid phagocytosis of the blood clot after hemorrhagic models of stroke.N-formyl peptide receptor 2(FPR2),a G-protein-coupled receptor,has been shown to be neuroprotective after ***2 activation has been associated with the upregulation of phagocytic macrophage clearance,yet its mechanism has not been fully *** literature suggests that FPR2 may play a role in the stimulation of scavenger receptor *** receptor CD36 plays a vital role in microglia phagocytic blood clot clearance after germinal matrix ***2 has been shown to phosphorylate extracellular-signal-regulated kinase 1/2(ERK1/2),which then promotes the transcription of the dual-specificity protein phosphatase 1(DUSP1)*** this review,we present an intrinsic outline of the main components involved in FPR2 stimulation and hematoma resolution after germinal matrix hemorrhage.

关键词： AnxA1 FPR2 GMH hematoma resolution hemorrhagic stroke M1 M2 microglia polarization microglia phagocytosis

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IDS-INT:Intrusion detection system using transformer-based transfer learning for imbalanced network traffic

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Digital Communications and Networks 2024年第1期10卷 190-204页

作者： Farhan Ullah Shamsher Ullah Gautam Srivastava jerry Chun-Wei Lin School of Software Northwestern Polytechnical UniversityXian710072ShaanxiChina Knowledge Unit of Systems and Technology University of Management and TechnologySialkot 51040Pakistan Department of Math and Computer Science Brandon UniversityBrandonMB R7A 6A9Canada Department of Computer Science and Math Lebanese American UniversityBeirut1102Lebanon Western Norway University of Applied Sciences BergenNorway Research Centre for Interneural Computing China Medical UniversityTaichungTaiwanChina

A network intrusion detection system is critical for cyber security against llegitimate *** terms of feature perspectives,network traffic may include a variety of elements such as attack reference,attack type,a subcategory of attack,host information,malicious scripts,*** terms of network perspectives,network traffic may contain an imbalanced number of harmful attacks when compared to normal *** is challenging to identify a specific attack due to complex features and data imbalance *** address these issues,this paper proposes an Intrusion Detection System using transformer-based transfer learning for Imbalanced Network Traffic(IDS-INT).IDS-INT uses transformer-based transfer learning to learn feature interactions in both network feature representation and imbalanced ***,detailed information about each type of attack is gathered from network interaction descriptions,which include network nodes,attack type,reference,host information,***,the transformer-based transfer learning approach is developed to learn detailed feature representation using their semantic ***,the Synthetic Minority Oversampling Technique(SMOTE)is implemented to balance abnormal traffic and detect minority ***,the Convolution Neural Network(CNN)model is designed to extract deep features from the balanced network ***,the hybrid approach of the CNN-Long Short-Term Memory(CNN-LSTM)model is developed to detect different types of attacks from the deep *** experiments are conducted to test the proposed approach using three standard datasets,i.e.,UNsWNB15,CIC-IDS2017,and *** explainable AI approach is implemented to interpret the proposed method and develop a trustable model.

关键词： Network intrusion detection Transfer learning Features extraction Imbalance data Explainable AI Cybersecurity

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DPK:Deep Neural Network Approximation of the First Piola-Kirchhoff Stress

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Advances in Applied Mathematics and Mechanics 2024年第1期16卷 75-100页

作者： Tianyi Hu jerry Zhijian Yang Cheng Yuan Institute of Artificial Intelligence School of Computer ScienceWuhan UniversityWuhanHubei 430072China School of Mathematics and Statistics Wuhan UniversityWuhanHubei 430072China Hubei Key Laboratory of Computational Science Wuhan UniversityWuhanHubei 430072China

This paper presents a specific network architecture for approximation of the first Piola-Kirchhoff *** neural network enables us to construct the constitutive relation based on both macroscopic observations and atomistic simulation *** contrast to traditional deep learning models,this architecture is intrinsic symmetric,guarantees the frame-indifference and material-symmetry of ***,we build the approximation network inspired by the Cauchy-Born rule and virial stress *** numerical results and theory analyses are presented to illustrate the learnability and effectiveness of our network.

关键词： Piola-Kirchhoff stress deep neural networks Cauchy-Born rule

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Aerodynamics of a Tandem-Bladed Axial Compressor Rotor under Circumferential Distortion at Different Rotational Speeds

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Journal of Thermal Science 2024年第4期33卷 1340-1356页

作者： Amit KUMAR jerry T.JOHN A.M.PRADEEP R.A.DAKKERMANS Dragan KOZULOVIC Department of Aerospace Engineering Indian Institute of Technology BombayMumbai400076India Department of Automotive and Aeronautical Engineering Hamburg University of Applied Sciences20099HamburgGermany Institute of Jet Propulsion Bundeswehr University Munich85577NeubibergGermany

For most aircraft engines,inflow distortion is *** distortion is known to degrade the aerodynamic performance and stable operating limits of a *** rotor configuration is an arrangement that effectively controls the growth of the boundary layer over the suction surface of the ***,a higher total pressure rise can be achieved through this unconventional design approach involving the splitting of the blade into forward and aft *** is expected that the effect of inlet flow distortion would be more severe for a tandem-rotor design due to the greater flow turning inherent in such ***,this aspect needs to be thoroughly *** present study discusses the effect of circumferential distortion on the tandem-rotor at different rotational ***-annulus RANS simulations using ANSYS CFX are used in the present *** performance of the rotor at a particular flow coefficient and different rotational speeds is *** total pressure and efficiency are observed to drop at lower mass flow rates under the influence of circumferential *** loss region in each blade passage is mainly associated with the blade wake,tip leakage vortex,secondary flow,and boundary ***,their contribution varies from passage to passage,particularly in the distorted *** the lower span,the wake width is found to be higher than that at a higher *** to the redistribution of the mass flow,the circumferential extent reduces at a higher *** the undistorted sector,the strength of the tip leakage vortex is significantly higher at the design rotational speed than at lower *** distortion near the tip region promotes an early vortex breakdown even at the design operating *** adversely affects the total pressure,efficiency,and stall *** clean flow conditions,this phenomenon is only observed near the stall *** the design operating condition,the breakdown of the forward rotor tip l

关键词： tandem rotor circumferential distortion loss tip leakage vortex vortex breakdown diffusion factor aerodynamics of compressor blade

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Analysis of Deep Ritz Methods for Semilinear Elliptic Equations

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Numerical Mathematics(Theory,Methods and Applications) 2024年第1期17卷 181-209页

作者： Mo Chen Yuling Jiao Xiliang Lu Pengcheng Song Fengru Wang jerry Zhijian Yang School of Mathematics and Statistics Wuhan University299 Ba Yi RoadWuhan 430072P.R.China Hubei Key Laboratory of Computational Science Wuhan University299 Ba Yi RoadWuhan 430072P.R.China

In this paper,we propose a method for solving semilinear elliptical equa-tions using a ResNet with ReLU2 ***,we present a comprehensive formulation based on the penalized variational form of the elliptical *** then apply the Deep Ritz Method,which works for a wide range of *** obtain an upper bound on the errors between the acquired solutions and the true solutions in terms of the depth D,width W of the ReLU2 ResNet,and the num-ber of training samples *** simulation results demonstrate that our method can effectively overcome the curse of dimensionality and validate the theoretical results.

关键词： Semilinear elliptic equations Deep Ritz method ReLUMo ResNet convergence rate

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Responses of growth performance,antioxidant function,small intestinal morphology and mRNA expression of jejunal tight junction protein to dietary iron in yellow-feathered broilers

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Journal of Integrative Agriculture 2024年第4期23卷 1329-1337页

作者： Kaiwen Lei Hao Wu jerry W Spears Xi Lin Xi Wang Xue Bai Yanling Huang Key Laboratory of Animal Science of State Ethnic Affairs Commission Southwest Minzu UniversityChengdu 610041China Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Southwest Minzu UniversityChengdu 610041China Department of Animal Science North Carolina State UniversityRaleighNC 27695-7621USA

This study aimed to investigate the dose-effect of iron on growth performance,antioxidant *** morphology,and mRNA expression of jejunal tight junction protein in 1-to21-d-old yellow-feathered broilers.A total of 7201-d-old yellow-feathered maleb roilers were allocated to 9 treatments with 8 replicate cages of 10 birds per *** dietary treatments were consisted of a basal diet(contained 79.6 mg Fe kg^(-1))supplemented with 0,20,40,60,80,160,320,640,and 1,280 mg Fe kg^(-1)in the form of FeSO_(4)·7H_(2)*** with the birds in the control group,birds supplemented with 20mg Fe kg^(-1)had higher average daily gain(ADG)(Plly(Pllus height(VH)in duodenum and jejunum,and the ratio of villus height to crypt depth(V/C)in duodenum decreased linearly(P?0.05)as dietary *** dietary Fe increased,the jejunal relative mRNA abundance of claudin-1 decreased linearly(P=0.001),but the jejunal relative mRNA abundance of zona occludens-1(ZO-1)and occludin decreased linearly(P?0.05)or quadratically(P?0.05).Compared with the supplementation of 20 mg Fe kg^(-1),the supplementation of640 mg Fe kg^(-1)or higher increased(P?0.05)MDA concentrations in plasma,duodenum,and jejunum,decreased VH in the duodenum and jejunum,and the addition of 1,280 mg Fe kg^(-1)reduced(P?0.05)the jejunal tight junction protein(claudin-1,ZO-1,occludin)mRNA *** summary,640 mg of supplemental Fe kg^(-1)or greater was associated with decreased growth performance,increased oxidative stress,disrupted intestinal morphology,and reduced mRNA expression of jejunal tight junction protein.

关键词： iron yellow-feathered broiler antioxidant function intestinal morphology tight junction protein

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Chemical Determination of Base Status Metals in Soil Sediments and Particulate Matter in Wellington Industrial Estate Location

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Open Journal of Applied Sciences 2024年第5期14卷 1338-1352页

作者： Richard Tamba Simbo jerry Yeke Paye Fayia Francis Nyuma Department of Chemistry School of Basic Sciences Njala University Freetown Sierra Leone Department of Science and Mathematics College of Arts and Sciences William V.S. Tubman University Harper Liberia Department of Fisheries and Science Thomas J.R Faulkner College of Science and Technology University of Liberia Monrovia Liberia

This research study explored the levels of base status metals in soil sediments and particulate matter in the wellington industrial estate location;the main objectives were to: 1) determine sodium and potassium, 2) determine calcium and magnesium, 3) determine available iron. The following hypotheses were put forward;H0a: there is no significant difference in the concentration levels between Ca and Mg in the study area, H1a: there is significant difference in the concentration levels between Ca and Mg in the study area, H0b: there is no significant difference in the concentration levels between Na and K in the study area, H1b: there is significant difference in the concentration levels between Na and K in the study area. Six locations were used to collect samples with the aid of scoop and gravel free auger (at varying depths of 0 - 5 cm and 5 - 10 cm) which are Wellington Industrial Estate Area 1 (WIEL 1), (WIEL 2), (WIEL 3), (WIEL 4), (WIEL 5), (WIEL 6);the samples were given laboratory treatment. Flame photometer, EDTA, and Spectrophotometer were used in the determinations of sodium and potassium, calcium and magnesium, and available iron respectively. The results indicated that levels of potassium were in medium range (moderately high);sodium levels were generally low when compared to Brook’s classification table. Levels of calcium were generally low and those of magnesium were moderate based on Brook’s table of classification. Levels of available iron which fall within the range of Quijano-Guerta (2003) were high;this implies such levels can lead to toxicity. In all locations, there was decrease in the levels of each metal in the samples with (5 - 10 cm) depth.

关键词： Deposition Environment Particulate Sediment Toxicity

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涨跌停制度变革、股票流动性与资本市场表现

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金融研究 2024年第3期 113-131页

作者：赵家悦卢锐柳建华 jerry Cao 中山大学商学院广东深圳518107 中山大学管理学院/现代会计与账务研究中心广东广州510275 中山大学岭南学院广东广州510275 香港恒生大学商学院中国香港999077

完善的资本市场基础制度,是建设高质量资本市场的根本保障。本文以创业板放宽涨跌幅限制至20%作为准自然实验,细致研究涨跌停制度变革的政策效应。首先,我们意外地发现,放宽涨跌幅限制后,触及10%涨跌幅的样本比例反而明显减少,且股价受... 详细信息

完善的资本市场基础制度,是建设高质量资本市场的根本保障。本文以创业板放宽涨跌幅限制至20%作为准自然实验,细致研究涨跌停制度变革的政策效应。首先,我们意外地发现,放宽涨跌幅限制后,触及10%涨跌幅的样本比例反而明显减少,且股价受到冲击后的表现也更加平稳。然后,我们考察股票流动性这一底层核心要素发现,实施涨跌停制度变革后,股票流动性显著提升:具体而言,每亿元成交量所引发的股价冲击幅度下降了大约0.73个百分点,相当于在同等规模的市场成交下,股票价格所受到的冲击减小了近五分之一。机制分析表明,涨跌停制度变革能够有效减少投资者的“羊群行为”,且有助于抑制过度投机,继而改善股票流动性。最后,对政策效果进行拓展性分析发现,涨跌停制度变革提高了市场定价效率,但并不会提升市场风险,从而回应了投资者对于该政策可能加剧市场风险的关切。本文的研究结果证实了涨跌停制度变革的适当性与必要性,表明这一变革符合我国发展高质量资本市场的长期目标,并为进一步深化资本市场改革提供了经验证据。

关键词：涨跌停制度变革股票流动性投资者行为市场定价效率流动性风险

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Therapeutic smart-footwear approach for management of neuropathic diabetic foot ulcers:Current challenges and focus for future perspective

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Medicine in Novel Technology and Devices 2024年第3期23卷 1-13页

作者： Stanley I.R.Okoduwa Bernard E.Igiri jerry I.Tagang Ugochi J.Okoduwa Abraham O.Adeyi Directorate of Research and Development Nigerian Institute of Leather and Science TechnologyZariaNigeria Department of Biochemistry School of Basic Medical SciencesBabcock UniversityIlishan-RemoNigeria Department of Footwear Technology Nigerian Institute of Leather and Science TechnologyZariaNigeria Industrial and Environmental Pollution Department National Research Institute for Chemical TechnologyZariaNigeria

Diabetic foot ulcers(DFU)have been connected to rising global mortality *** increased plantar tissue stress beneath the numb foot of neuropathy patients is associated with *** article summarises essential therapeutic footwear concepts for the treatment of DFUs and shows how new sensor technologies have made this *** with neuropathic DFUs can address their foot problems with therapeutic footwear without being constrained in their daily *** intervention in maintaining DFUs must be discrete,power-efficient,accurate,and user-friendly in order to offer a trustworthy and acceptable way for effective health *** device can be inserted into a person's shoes from the plantar aspect of the foot to gather more information about their *** findings showed that weight-bearing activities and sensor offloading devices can be employed as effective offloading therapies to heal *** article examines the therapeutic footwear-based technological sensor system,which keeps track of many elements that are helpful in tracking foot ulcers,available treatments,and potential research areas in the future.

关键词： Diabetic foot ulcer Therapeutic footwear Sensors Neuropathy Plantar pressure

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声靓型更靓,球型音箱推荐

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家庭影院技术 2024年第7期339卷 86-91页

作者： jerry 不详

相信大多数人对音响的印象还停留在传统的方正盒子型。然而,随着科技的进步和审美的发展,音箱的外在形态也变得更加多样化。如今的音响从外观上来看,已经呈现出干奇百怪的多元化发展趋势。除了常见的方盒子状,还有许多形态各异的音响,... 详细信息

相信大多数人对音响的印象还停留在传统的方正盒子型。然而,随着科技的进步和审美的发展,音箱的外在形态也变得更加多样化。如今的音响从外观上来看,已经呈现出干奇百怪的多元化发展趋势。除了常见的方盒子状,还有许多形态各异的音响,圆柱型、三角型、球型,甚至是由多种几何图案拼接而成的造型,比如Bowers&Wilkins传奇的鹦鹉螺、KEF的MUON等等。目前我们可以观察到,一些不常见造型的音箱大多以有源音箱或蓝牙音箱的形式存在。本期内容的主题将围绕球型音响展开,简单快速讨论球型音箱的来历、优缺点,并列举四个市面上生产球型音响的主流品牌及其推荐产品。

关键词：有源音箱主流品牌球型方盒子 KEF 蓝牙音箱外在形态圆柱型

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