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Brain-de.ive. ne.rotrophic factor(BDNF) as a pote.tial me.hanism of the.e.fe.ts of acute.e.e.cise.on cognitive.pe.formance

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Journal of Sport and He.lth Scie.ce 2015年第1期4卷 14-23页

作者： Aaron T.Pie.me.e. jennifer L.e.nie. De.artme.t of Kine.iology University of North Carolina at Greensboro

The.lite.ature.shows that improve.e.ts in cognitive.pe.formance.may be.obse.ve. following an acute.bout of e.e.cise. Howe.e., e.ide.ce.in support of the.biological me.hanisms of this e.fe.t is still limite.. Findings from both rode.t and human studie. sugge.t brain-de.ive. ne.- rotrophic factor （BDNF） as a pote.tial me.hanism of the.e.fe.t of acute.e.e.cise.on me.ory. The.mole.ular prope.tie. of BDNF allow this prote.n to be.asse.se. in the.pe.iphe.y （pBDNF）（i.e., blood se.um, blood plasma）, making me.sure.e.ts of acute.e.e.cise.induce. change. in BDNF conce.tration re.ative.y acce.sible. Studie. e.ploring the.acute.e.e.cise.-pBDNF--cognitive.pe.formance.re.ationship have.had mixe. findings, but this may be.more.re.le.tive.of me.hodological diffe.e.ce. be.we.n studie. than it is a state.e.t about the.role.of BDNe.For e.ample. significant associations have.be.n obse.ve. be.we.n acute.e.e.cise.induce. change. in pBDNF conce.tration and cognitive.pe.formance.in studie. asse.sing me.ory, and non-significant associations have.be.n found in studie. asse.sing non-me.ory cognitive.domains. Thre. sugge.tions are.made.for future.re.e.rch aime. at unde.standing the.role.of BDNF as a biological me.hanism of this re.ationship： 1） Asse.sme.ts of cognitive.pe.formance.may be.e.it from a focus on various type. of me.ory （e.g., re.ational, spatial, long-te.m）; 2） More.fine.raine. me.sure.e.ts of pBDNF will allow for the.asse.sme.t of conce.trations of spe.ific isoforms of the.BDNF prote.n （i.e., immature. mature.; 3） Statistical te.hnique. de.igne. to te.t the.me.iating role.of pBDNF in the.acute.e.e.cise.cognitive.pe.formance.re.ationship should be.utilize. in orde. to make.causal infe.e.ce..

关键词： Isoforms Me.iators Me.ory Me.tal he.lth Physical activity

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Nitroge. Dioxide.and Ozone.Pollution in the.Chicago Me.ropolitan Are.

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Journal of e.vironme.tal Prote.tion 2020年第8期11卷 551-569页

作者： Zixian Wang jennifer L. Anthony Larry e. e.ickson Michae. J. Higgins Gre.ory L. Ne.mark Tim Taylor De.artme.t of Che.ical e.gine.ring Kansas State University Manhattan KS USA De.artme.t of Statistics Kansas State University Manhattan KS USA De.artme.t of Landscape.Archite.ture.Re.ional and Community Planning Kansas State University Manhattan KS USA

Ground-le.e. ozone.is a harmful air pollutant associate. with se.e.al he.lth issue.. Ozone.conce.trations have.e.ce.de. the.National Ambie.t Air Quality Standards (NAAQS) in the.Chicago me.ropolitan are. on hot summe. days for many ye.rs be.ause.of nitroge. oxide.and volatile.organic compound e.issions. Annual fourth highe.t 8-hour ozone.conce.trations have.be.n be.we.n 0.070 and 0.084 ppm at se.e.al monitoring site. in Cook county, during the.2016-2018 time.pe.iod. The.continuous me.sure.e.t of nitroge. dioxide.(NO2) and ozone.(O3) was conducte. in se.e.al communitie. in Chicago in 2017. The.air pollution impacts the.he.lth of all who live.in the.are.. The.data we.e.use. to analyze.corre.ations be.we.n the.O3 distribution and its association with ambie.t conce.trations of NO2 from transportation e.issions. Highe. conce.trations in NO2 and O3 occurre. in succe.sion in the.daytime. The.diurnal variation of O3 conce.tration was analyze.. The.daily cycle.of NO2 conce.tration re.che. a maximum in the.late.morning and has smalle. nighttime.conce.trations. The.daily cycle.of ozone.conce.tration re.che. the.maximum in the.afte.noon and also be.ome. smalle. for nighttime.conce.trations. In addition, re.ationships we.e.found be.we.n O3 and NO2. Monthly variations of ozone.and NO2 are.pre.e.te.. Some.options to re.uce.ozone.pollution are.pre.e.te..

关键词： Volatile.Organic Compounds He.lth Ve.icle.e.issions Daily Transie.t Cycle. Ozone.Pre.ursors Photoche.ical Re.ctions

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e.ploring the.band structure.of Wurtzite.InAs nanowire. using photocurre.t spe.troscopy

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Nano Re.e.rch 2020年第6期13卷 1586-1591页

作者： Se.ye.e.adaf Pournia Samue. Linse. Giriraj Jnawali Howard e.Jackson Le.gh M.Smith Amira Ame.uddin Philippe.Caroff jennifer Wong-Le.ng Hark Hoe.Tan Che.nupati Jagadish Hannah J.Joyce De.artme.t of Physics University of CincinnatiCincinnatiOH45221-0011USA De.artme.t of e.e.tronic Mate.ials e.gine.ring Research School of PhysicsThe Australian National UniversityCanberraACT2601Australia De.artme.t of e.gine.ring University of Cambridge9 JJ Thomson AvenueCambridgeCB30FAUK

Nano Re.e.rch volume.We.use.polarize. photocurre.t spe.troscopy in a nanowire.de.ice.to inve.tigate.the.band structure.of he.agonal Wurtzite.*** of optical transitions be.we.n four vale.ce.bands and two conduction bands are.obse.ve. which are.consiste.t with the.symme.rie. e.pe.te. from group *** ground state.transition e.e.gy ide.tifie. from photocurre.t spe.tra is se.n to be.consiste.t with photolumine.ce.ce.e.itte. from a cluste. of nanowire. from the.same.growth *** the.e.e.gie. of the.obse.ve. bands we.de.e.mine.the.spin orbit and crystal fie.d e.e.gie. in Wurtzite.*** information is vital to the.de.e.opme.t of crystal phase.e.gine.ring of this important III-V se.iconductor.

关键词： nanowire. Wurtzite.InAs photocurre.t me.sure.e.t optical se.e.tion rule. e.e.gy band structure

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Pote.t and conditional re.ire.te. T ce.l killing of tumor ce.ls using Half DVD-Ig

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Prote.n & Ce.l 2018年第1期9卷 121-129页

作者： Philip D. Bardwe.ll Matthe. M. Staron Junjian Liu Qingfe.g Tao Susanne.sce.ne. Gail Bukofze. Luis e. Rodrigue. Che.-Ho Choi jennifer Wang Qing Chang Fe.g Dong Che.rie.Donawho Jie.i Wang Christine.M. Grinne.l e.it Tarcsa Charle. Hutchins Tariq Ghayur Jijie.Gu Foundational Immunology AbbVie Bioresearch Center Worcester MA 01605 USA Global Pre.linical Safe.y AbbVie Bioresearch Center Worcester MA 01605 USA Oncology Discove.y AbbVie Inc. North Chicago IL 60064 USA DMPK-BA AbbVie Bioresearch Center Worcester MA 01605 USA Re.e.rch and De.e.opme.t AbbVie Inc. North Chicago IL 60064 USA Torque.The.ape.tics Inc. Cambridge MA 02142 USA Innove.t Bioloqics Inc. Suzhou China Lyvge. Biopharma Shanghai 201203 China

Nove. biologics that re.ire.t cytotoxic T lymphocyte. （CTLs） to kill tumor ce.ls bearing a tumor associate. antige. hold gre.t promise.in the.clinic. Howe.e., the.ability to safe.y and pote.tly targe. CD3 on CTL toward tumor associate. antige.s （TAA） e.pre.se. on tumor ce.ls re.ains a challe.ge.of both te.hnology and biol- ogy. He.e.n we.de.cribe.the.use.of a Half DVD-Ig format that can re.ire.t CTL to kill tumor ce.ls. Notably, Half DVD-Ig mole.ule. that are.monovale.t for e.ch spe.i- ficity de.onstrate. re.uce. non-spe.ific CTL activation and conditional CTL activation upon binding to TAA compare. to intact te.ravale.t DVD-Ig mole.ule. that are.bivale.t for e.ch spe.ificity, while.maintaining good drug like.prope.tie. and appropriate.PK prope.tie..

关键词： DVD-Ig Half DVD-Ig Halt'body e.ide.mal growth factor re.e.tor re.ire.te. T-ce.l cytotoxicity rCTL

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Source. and e.vironme.tal fate.of pyroge.ic polycyclic aromatic hydrocarbons(PAHs)in the.Arctic

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e.e.ging Contaminants 2019年第1期5卷 128-142页

作者： jennifer e.Balme. Hayle. Hung Yong Yu Robe.t J.Le.che. De.e. C.G.Muir Arctic Monitoring and Asse.sme.t Programme Fram CentrePO Box 6606 Langnes9296TromsøNorway De.artme.t of Biology The Citadel171 Moultrie StreetCharlestonSC29409USA Air Quality Proce.se. Re.e.rch Se.tion Environment and Climate Change Canada4905 Dufferin StreetTorontoOntarioM3H 5T4Canada Northe.st Institute.of Ge.graphy and Agroe.ology Chinese Academy of SciencesChangchun130102China e.otoxicology and Wildlife.He.lth Division Environment and Climate Change CanadaNational Wildlife Research CentreCarleton UniversityRaven RoadOttawaOntarioK1A 0H3Canada e.vironme.t and Climate.Change.Canada Canada Centre for Inland Waters867 Lakeshore RoadBurlingtonONL7S 1A1Canada

Polycyclic aromatic hydrocarbons(PAHs)are.large.class of hydrophobic,se.i-volatile.organic contaminants that may e.te. the.e.vironme.t from both natural source. and anthropoge.ic *** PAHs arise.from the.incomple.e.combustion of fossil fue.s and organic matte. and following dispe.sal via long-range.transport and may subse.ue.tly de.osit in surface.wate.s,soils and se.ime.ts of re.ote.re.ions,including the.*** curre.t re.ie. summarize. and discusse. Arctic data that is available.for combustion-de.ive. PAHs be.we.n 2004 and e.rly 2018,focusing large.y on data colle.te. from re.ote.une.ploite. Arctic re.ions and from studie. that provide.some.e.ide.ce.of a pyroge.ic *** incre.sing use.of attribution ratios,which aid in discriminating PAHs from pe.roge.ic or pyroge.ic source.,sugge.t PAHs found in Arctic marine.wate.s and se.ime.t pre.ominantly originate.from natural unde.wate. se.ps,while.those.me.sure. in air,fre.hwate.,and te.re.trial e.vironme.ts are.like.y to have.originate. from atmosphe.ic and combustion-de.ive. *** e.forts indicate.that atmosphe.ic PAHs in the.Canadian and Norwe.ian Arctic are.like.y to have.originate. in the.northe.n he.isphe.e.e.pre.ominantly from We.te.n Russia,northe.n e.rope.and North *** Asia appe.rs to be.a minor source.of PAHs to the.Arctic,de.pite.contributing more.than 50%of global PAH *** comparison to the.growing data for atmosphe.ic PAHs,e.vironme.tal data for the.e.compounds in te.re.trial and fre.hwate. e.vironme.ts re.ain *** have.be.n de.e.te. in Arctic biota from te.re.trial,fre.hwate. and marine.e.vironme.ts,indicating e.posure.howe.e.,le.e.s are.ge.e.ally low,as most organisms e.ficie.tly me.abolize.pare.t ***,PAH e.issions are.e.pe.te. to de.line.in the.future.howe.e. mode.s sugge.t the.Arctic may not e.pe.ie.ce.the.same.magnitude.of de.line.proje.te. for othe. world ***,future.change. in climate.may contribute.to a re.volatilizati

关键词： Contaminants Air Biota Pyroge.ic Pe.roge.ic Re.ie.

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Post-fire.re.e.e.ation dynamics in white.ark pine.Pinus albicaulis) fore.ts in Wind Rive. and Absaroka Mountains,Wyoming, USA

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Journal of Fore.try Re.e.rch 2015年第3期26卷 719-733页

作者： jennifer G.Klutsch Be.sy A.Goodrich William R.Jacobi De.artme.t of Bioagricultural Scie.ce. and Pe.t Manage.e.t Colorado State University Ft. CollinsCO 80523-1177 USA De.artme.t of Re.e.able.Re.ource. University of Alberta 442 Earth Science BuildingEdmonton AB T6G 2E3 Canada School of Fore.try Northern Arizona University PO Box 15018 Flagstaff AZ 86011 USA

White.ark pine.（Pinus albicaulis） populations are.in de.line.across the.spe.ie.＇ range.due.to historic wildfire.e.clusion, mountain pine.be.tle.（De.droctonus ponde.osae. MPB） outbre.ks, and an invasive.fungal pathoge. causing the.dise.se.white.pine.bliste. rust （Cronartium ribicola, WPBR）. De.pite.re.iance.on stand- re.lacing fire., information on white.ark pine.re.e.e.ation occurre.ce.is limite. and the.traje.tory of future.fore.ts is large.y unknown in some.are.s of the.range. Re.e.e.ation de.sitie. we.e.asse.se. in burne. and adjace.t non-burne. are.s at six high e.e.ation locations in northwe.t Wyoming whe.e.stand-re.lacing fire. occurre. 8-32 ye.rs be.ore.the.urve.s. In the.e.locations at the.e.ste.n e.te.t of the.spe.ie. range. we.asse.se. what site.factors we.e.associ- ate. with re.e.e.ation succe.s. White.ark pine.re.e.- e.ation de.sity was gre.te. and se.dlings we.e.olde. in non-burne. compare. to burne. are.s. Within burns, north aspe.ts had more.re.e.e.ation than south aspe.ts. Pote.tial se.d source.de.sitie. and othe. spe.ie.＇ re.e.e.ation we.e.positive.y re.ate. to white.ark p^ne.re.e.e.ation de.sitie. in burne. are.s. South facing slope. or grass cove.e. are.s may have.e.the. de.aye. or no re.e.e.ation of white.ark pine.without the.he.p of artificial planting.

关键词： Re.ruitme.t Age.structure White.pine.liste. rust - Mountain pine.be.tle Re.toration

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He.achlorobutadie.e.HCBD)contamination in the.Arctic e.vironme.t:A re.ie.

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e.e.ging Contaminants 2019年第1期5卷 116-122页

作者： jennifer e.Balme. Hayle. Hung Katrin Vorkamp Robe.t J.Le.che. De.e. C.G.Muir Arctic Monitoring and Asse.sme.t Programme Fram CentrePO Box 6606 Langnes9296TromsøNorway De.artme.t of Biology The Citadel171 Moultrie StreetCharlestonSC29409USA Air Quality Proce.se. Re.e.rch Se.tion Environment and Climate Change Canada4905 Dufferin StreetTorontoOntarioM3H 5T4Canada Aarhus Unive.sity Department of Environmental ScienceArctic Research CentreFrederiksborgvej 3994000RoskildeDenmark e.otoxicology and Wildlife.He.lth Division Environment and Climate Change CanadaNational Wildlife Research CentreCarleton UniversityRaven RoadOttawaOntarioK1A 0H3Canada e.vironme.t and Climate.Change.Canada Canada Centre for Inland Waters867 Lakeshore RoadBurlingtonONL7S 1A1Canada

He.achlorobutadie.e.HCBD)is a haloge.ate. hydrocarbon that is primarily produce. as an uninte.tional byproduct in the.manufacture.of chlorinate. *** be.we.n HCBD and othe. pe.siste.t organic pollutants(POPs)le. to its listing in 2015 for global re.ulation unde. the.Stockholm Conve.tion on ***'s toxicity and prope.sity for long-range.transport me.ns the.e.is spe.ial conce.n for its pote.tial impacts on Arctic *** pre.e.t re.ie. compre.e.sive.y summarize. all available.information of the.occurre.ce.of HCBD in the.Arctic e.vironme.t,including its atmosphe.ic,te.re.trial,fre.hwate. and marine.e.osyste.s and ***,re.orts of HCBD in Arctic e.vironme.tal me.ia are.*** has be.n me.sure. in Arctic air colle.te. from monitoring stations in Finland and Canada,ye. the.e.is a de.rth of data for othe. abiotic matrice.(***,se.ime.ts,glacie. ice.fre.hwate.s and se.wate.).Low HCBD conce.trations have.be.n me.sure. in Arctic te.re.trial and marine.biota,which is consiste.t with laboratory studie. that indicate.that HCBD has the.pote.tial to bioaccumulate.but not to *** data for Arctic biota sugge.t that te.re.trial birds and mammals and se.birds,have.comparative.y highe. HCBD conce.trations than fish and marine.mammals,warranting additional *** spatial and te.poral tre.ds in HCBD conce.trations in the.Arctic are.curre.tly limite.,future.monitoring of HCBD in the.Arctic will be.important for asse.sing the.impact of global re.ulations ne.ly-impose. by the.Stockholm Conve.tion on POPs.

关键词： POPs Air Biota Contaminants Long-range.transport Re.ie.

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Association be.we.n Pre.e.ce.of Urovirule.ce.Factors, Phyloge.e.ic Class, and Antimicrobial Re.istance.Patte.ns in 159 Uropathoge.ic <i>e.che.ichia coli</i>Sample. Isolate. from Dogs

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Ope. Journal of Ve.e.inary Me.icine 2013年第2期3卷 199-203页

作者： jennifer e. We.ls Jose.h W. Bartge. Ste.he. A. Kania David A. Be.is Te. Gluhak De.artme.t of Small Animal Clinical Scie.ce. The University of Tennessee Knoxville USA

The.purpose.of this study was to e.amine.four urovirule.ce.factors (UVFs) and the.r phyloge.e.ic classe. and compare.the.r le.e.s of re.istance.to antimicrobial drug classe. in 159 canine.uropathoge.ic e. coli (UPe.) isolate. submitte. to the.Clinical bacte.iology and Mycology Laboratory of The.Unive.sity of Te.ne.se. Ve.e.inary Me.ical Ce.te. in 2007. Multiple. polyme.ase.chain re.ction was use. to de.e.t the.following UVFs: cytotoxic ne.rotizing factor (cnf), he.olysin (hly), S-fimbrial adhe.ion ge.e.(sfa), and Pilus associate. with pye.one.hritis ge.e.G alle.e.III (pap);polyme.ase.chain re.ction was use. to de.e.mine.phyloge.e.ic group. In vitro susce.tibility to antimicrobial classe. was e.aluate., and re.istance.was compare. to UVF pre.e.ce.as we.l as phyloge.e.ic class. UVFs we.e.pre.e.te. in 48% of UPe. and we.e.ne.ative.y corre.ate. with antimicrobial re.istance. Of the.159 sample., the.numbe. of UVFs e.pre.se. pe. isolate.was 0 = 82 (52%), 1 = 24 (15%), 2 = 2 (1%), 3 = 18 (11%), and 4 = 33 (21%). The.following UVFs we.e.e.pre.se.: sfa (33%), hly (24%), cnf (25%), and pap (18%). Pre.e.ce.of all four UVFs, hly, cnf, and sfa toge.he., and sfa alone. was associate. with le.s re.istance.(P e.most common phyloge.e.ic class and containe. the.highe.t numbe. of UVFs (P e.n antimicrobial re.istance.was the.highe.t in class A (P e.lowe.t in B2 (P e.e.ic class A containe. the.lowe.t numbe. of UVFs.

关键词： Antimicrobials Cystitis Dog e.che.ichia coli

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Prone.Transpsoas Approach for Adjace.t Se.me.t Dise.se.and Flatback De.ormity: Te.hnical Note.and Case.Re.ort

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Ope. Journal of Mode.n Ne.rosurge.y 2021年第1期11卷 20-28页

作者： Timothy e. O’Connor Mary Margare. O’He.ir jennifer Z. Mao Je.fre. P. Mullin John Pollina De.artme.t of Ne.rosurge.y Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo Buffalo NY USA De.artme.t of Ne.rosurge.y Buffalo General Medical Center Kaleida Health Buffalo NY USA Jacobs School of Me.icine.and Biome.ical Scie.ce. at the.Unive.sity at Buffalo Buffalo NY USA

The.prone.transpsoas approach is a re.ative.y ne. te.hnique.to corre.t se.me.tal kyphosis and global sagittal imbalance.in a minimally invasive.fashion. He.e. we.provide.a de.aile. case.re.ort using the.prone.transpsoas approach to addre.s adjace.t se.me.t dise.se.and flatback de.ormity. This te.hnique.allows conside.able.re.toration of se.me.tal lordosis with late.al inte.body place.e.t and poste.ior de.ompre.sion and fusion using a single.position approach. Our e.pe.ie.ce.with the.surgical te.hnique.and the.advantage. and challe.ge. unique.to this approach are.discusse..

关键词： Prone.Transpsoas Adjace.t Se.me.t Dise.se Flatback De.ormity

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Compute. Tomographic Asse.sme.t of Body Fat in Dach-shunds: A Pilot Study

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Ope. Journal of Ve.e.inary Me.icine 2013年第1期3卷 1-5页

作者： Je.fre. F. Comstock jennifer L. Wardlaw e.in L. Brinkman-Fe.guson De.nis e. Rowe De.artme.t of Clinical Scie.ce. College of Veterinary Medicine Mississippi State University Mississippi USA

Obe.ity has not be.n linke. to causing inte.ve.te.ral disc de.e.e.ation, but has be.n shown to influe.ce.time.to ambulation, a strong long-te.m prognostic indicator in dogs with inte.ve.te.ral disc dise.se. Howe.e., monitoring obe.ity to date.is impre.ise.and subje.tive.in the.clinical se.ting. Having an obje.tive.formula base. on morphome.ric me.sure.e.ts would pote.tially be.more.pre.ise.to track our patie.ts’ we.ghts. Dogs have.be.n shown to gain we.ght along the.r lumbar spine.more.rapidly than othe. are.s. Varying body conformations make.e.trapolation from nonchondrodystrophic dogs to Dachshunds difficult. This study aime. to e.tablish the.re.ion of fat accumulation along the.thoracolumbar spine.in Dachshunds. Re.rospe.tive.compute. tomographic (CT) analysis was pe.forme. on he.lthy Dachshunds that pre.e.te. for inte.ve.te.ral disc dise.se.(IVDD). Fat are. me.sure. at L3 and L5 using atte.uation range. ﹣135/﹣105 Hounsfie.d units (HU) was the.most de.e.de.t on body we.ght (p = 0.05). The.e.appe.re. to be.no diffe.e.ce.be.we.n subcutane.us, visce.al or total pe.ce.t body fat with we.ght agre.me.t. T13, L3 and L5 all had line.r re.ationships with patie.t we.ght and will like.y be.he.pful for body mass inde. (BMI) formula cre.tion (p 0.01). This study indicate. that any consiste.t location be.we.n L3 and L5 will give.an accurate.re.re.e.tation of the.abdominal circumfe.e.ce.and most obe.e.are. of the.Dachshund with the.umbilicus use. as a landmark.

关键词： Compute. Tomography Body Fat Dachshund

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